Abstract: A pusher centrifuge includes a rotatable filter drum having a drum body and a piston that are configured to be reciprocated axially relative to one another, a filter drum drive shaft rigidly connected to the filter drum, a hydraulic push mechanism for generating an axial oscillating push force and connected to the filter drum so as to cause the relative reciprocating movement between the piston and the drum body, a hydraulic pump including a pump input shaft and is in fluid connection with the hydraulic push mechanism, and a drive motor including at least one output shaft connected to the pump input shaft and the filter drum drive shaft to actuate both the pump input shaft and the filter drum drive shaft. The at least one output shaft of the drive motor is connected to the pump input shaft in a manner without an intervening gearbox, thereby forming a direct drive.

Abstract: A vacuum and/or pressure filtration device includes a filter drum defining a drum axis and it is supported rotatably around the drum axis. The filter drum includes an outer jacket, by which a plurality of filter cells are formed, which extend along the drum axis, which are arranged adjacent to each other all around the drum axis, and which are equipped on their outer side with a filter medium; and an inner jacket, which is arranged adjacent to the outer jacket, which has an inner jacket outer surface, which limits the filter cells radially inside such that by the inner jacket outer surface a plurality of draining surfaces are formed, on which the liquid passing through the respective filter medium during filtration of the suspension can drain as a filtrate. The filtration device filters a suspension having solid and liquid components.

Abstract: The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.

Abstract: The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages. Various active ingredients may be incorporated, such as immunosuppressants, antiinfectives, antifungal agents, antiinflammatory agents, and retinoids.

Abstract: A filter drum including: a drive shaft via which the filter drum is rotatably supportable and rotatably drivable; a filter drum body which is formed in a manner separated from the drive shaft, to which the drive shaft extends centrally and which filter drum body includes a first drum end wall, a second drum end wall, and a drum jacket wall which extends along the drive shaft between the first drum end wall and the second drum end wall and connects the first drum end wall and the second drum end wall to each other; and a first clamping ring set and a second clamping ring set, corresponding to the first drum end wall and the second drum end wall, respectively, by which, in a respective manner, the first drum end wall and the second drum end wall are, via radial clamping, fixedly connected to the drive shaft such that a driving torque applied to the drive shaft is correspondingly transmittable from the drive shaft to the first drum end wall and/or the second drum end wall and, thereby, to the filter drum body vi

Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.

Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.

Abstract: The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.

Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.

Abstract: A filter drum including: a drive shaft via which the filter drum is rotatably supportable and rotatably drivable; a filter drum body which is formed in a manner separated from the drive shaft, to which the drive shaft extends centrally and which filter drum body includes a first drum end wall, a second drum end wall, and a drum jacket wall which extends along the drive shaft between the first drum end wall and the second drum end wall and connects the first drum end wall and the second drum end wall to each other; and a first clamping ring set and a second clamping ring set, corresponding to the first drum end wall and the second drum end wall, respectively, by which, in a respective manner, the first drum end wall and the second drum end wall are, via radial clamping, fixedly connected to the drive shaft such that a driving torque applied to the drive shaft is correspondingly transmittable from the drive shaft to the first drum end wall and/or the second drum end wall and, thereby, to the filter drum body vi

Abstract: A vacuum and/or pressure filtration device includes a filter drum defining a drum axis and it is supported rotatably around the drum axis. The filter drum includes an outer jacket, by which a plurality of filter cells are formed, which extend along the drum axis, which are arranged adjacent to each other all around the drum axis, and which are equipped on their outer side with a filter medium; and an inner jacket, which is arranged adjacent to the outer jacket, which has an inner jacket outer surface, which limits the filter cells radially inside such that by the inner jacket outer surface a plurality of draining surfaces are formed, on which the liquid passing through the respective filter medium during filtration of the suspension can drain as a filtrate. The filtration device filters a suspension having solid and liquid components.

Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of tacrolimus and a liquid vehicle comprising at least one semifluorinated alkane for use in a method of treating an intraocular inflammatory eye disease.

Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.

Abstract: The invention provides novel compositions of antibodies based on liquid vehicles selected from semifluorinated alkanes. The use of these vehicles provides for improved stability and shelf-life of antibodies and their derivatives. The compositions are useful for topical administration or for parenteral injection.

Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.

Abstract: The invention provides novel compositions of antibodies based on liquid vehicles selected from semifluorinated alkanes. The use of these vehicles provides for improved stability and shelf-life of antibodies and their derivatives. The compositions are useful for topical administration or for parenteral injection.

Abstract: The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.

Abstract: The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages. Various active ingredients may be incorporated, such as immunosuppressants, antiinfectives, antifungal agents, antiinflammatory agents, and retinoids.

Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.

Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.