Abstract: The invention relates to a topical nanoparticulate spironolactone formulation comprising nanoparticles having a mean diameter, measured by a photon correlation spectroscopy, in the range of from about 300 nm to about 900 nm. The nanoparticles are incorporated into a crystalline network system comprising a dispersion of solid crystals of polar lipids, said lipids exposing their hydrophilic side outwards and their hydrophobic side inwards towards the spironolactone nanoparticles.

Abstract: An LMDS system including a base station, subscriber units and subscriber modems. Transmission frequencies between the base station and the subscriber units are specified by the Federal Frequency Commission. Signal frequencies between the subscriber units and the subscriber modems are specified by industry standards. The subscriber units couple and frequency translate modulated signals between the base stations and the subscriber modems. The frequency translation requires an intermediate transmit oscillator and a local oscillator. The intermediate transmit oscillator, however, can also be used to frequency translate a local oscillator signal within each subscriber unit down to a lower frequency which allows a low cost phase locked loop chip to be used to phase lock the local oscillator in each subscriber unit to a reference source. A pilot tone can be coupled onto modulated signals transmitted from the base station to the subscriber units.

Abstract: Transmit and receive programmable band select/transfer modules provide low cost means for selecting and translating spectral segments within sectors of a LMDS basestation. The modules are programmable to select spectral segments and translate the frequency of the selected segments to designated spectral positions in the sector's output signal. Each module shifts the frequency of an applied uwave signal to dispose a predetermined spectral segment about an IF frequency. The predetermined spectral segment is then selected using a fixed frequency filter at the IF frequency. The spectral segment has one of several bandwidths, selected by one of multiple fixed frequency filters in the modules. The module translates the frequency of the filtered spectral segment to dispose the selected spectral segment about an output frequency to provide the sector's output signal. An optional pilot signal or service channel may be summed with the filtered spectral segment prior to the frequency translation.

Abstract: Apparatus and method for extending the effective dynamic range of pulse measure and pulse display devices by providing dynamic gain switching, with an associated gain or attenuation coefficient that assumes one of a plurality of two or more values, depending on the instantaneous magnitude of the signal received or upon the choice of an external controller. The amplification path may be one of a plurality of mutually exclusive parallel paths. Alternatively, the amplification path may be a serial combination of an arbitrary subset of a collection of amplification paths. The choice of amplification path may be made automatically by a fast-acting sensor such as a signal comparator or may be made by an external control provided by a human operator or computer and may be overridden by an externally produced control override signal.