Abstract: Disclosed herein are compounds or pharmaceutically acceptable salts thereof that are useful as inhibitors for activity of a BAF complex. Also disclosed are pharmaceutical compositions comprising such compounds, and methods of using such compounds or compositions to treat BAF complex-related disorders.

Abstract: Techniques for creating an interest graph include obtaining content items from multiple content sources and applying tailored (e.g., source-specific) preprocessing to the content items based on their respective content source. Text is extracted and salient keywords and key phrases are identified using unsupervised machine learning models. The keywords and key phrases become nodes in an interest graph, each node comprising an embedding of a keyword or key phrase in a common embedding space, with edges representing semantic similarity based on embeddings or co-engagement patterns. The graph provides an expansive, granular, and dynamic taxonomy easily adaptable to emerging interests. The interest graph overcomes limitations of conventional taxonomies that lack depth, fail to capture niche interests, and cannot adapt to reflect evolving user preferences. The described techniques construct a rich interest graph from diverse content for improved content understanding.

Abstract: A construction method for reconstructing and expanding a ship lock in suit is provided. A flood gate in an upper lock head section of a constructed ship lock is used as a water-retaining cofferdam during a construction period. A remaining part of the constructed ship lock is cut off downstream from a target cutting surface located in a lock chamber section of the constructed ship lock, and a new ship lock is constructed downstream. A bank-side pier structure between the upper lock head section of the constructed ship lock and the new ship lock is cut to a first preset elevation, and two water-retaining and seepage control lines are added, and a cutoff buttress is constructed. An upper navigation wall section of the constructed ship lock and the upper lock head section of the constructed ship lock are reconstructed, and another water-retaining and seepage control line is added.

Abstract: A combined display method includes: the mobile device broadcasts a first message in response to receiving a first input, where the first message indicates that the combined display needs to be performed; the mobile device obtains a first image, where the first image includes a first display and a second display, the first display displays first information, and the second display displays second information; the mobile device sends a second message to a first electronic device, where the second message includes the first information, the second information, orientation information of the first display and the second display, a size proportion relationship between the first display and the second display, and a correspondence between the first information and the first display; and the first electronic device controls, in response to receiving the second message, a plurality of electronic devices to perform combined display.

Abstract: Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.

Abstract: Techniques for creating an interest graph include obtaining content items from multiple content sources and applying tailored (e.g., source-specific) preprocessing to the content items based on their respective content source. Text is extracted and salient keywords and key phrases are identified using unsupervised machine learning models. The keywords and key phrases become nodes in an interest graph, each node comprising an embedding of a keyword or key phrase in a common embedding space, with edges representing semantic similarity based on embeddings or co-engagement patterns. The graph provides an expansive, granular, and dynamic taxonomy easily adaptable to emerging interests. The interest graph overcomes limitations of conventional taxonomies that lack depth, fail to capture niche interests, and cannot adapt to reflect evolving user preferences. The described techniques construct a rich interest graph from diverse content for improved content understanding.

Abstract: A power line communication-based pairing method and device for an air conditioner, and a storage medium are provided. Based on a pairing request instruction, A CCO module on an indoor side selects an STA module to be paired, in a power line network, for use as a pairing object. The CCO module sends pairing request information to the power line network. The STA module receives the pairing request information. If the STA module determines that identification information thereof exists in the pairing request information, the STA module establishes a pairing relationship with the CCO module. The STA module sends pairing feedback information to the power line network. The CCO module receives the pairing feedback information. If the CCO module determines that the identification information thereof exists in the pairing feedback information, the CCO module determines that the pairing is successful and establishes a pairing relationship with the STA module.

Abstract: Techniques for creating an interest graph include obtaining content items from multiple content sources and applying tailored (e.g., source-specific) preprocessing to the content items based on their respective content source. Text is extracted and salient keywords and key phrases are identified using unsupervised machine learning models. The keywords and key phrases become nodes in an interest graph, each node comprising an embedding of a keyword or key phrase in a common embedding space, with edges representing semantic similarity based on embeddings or co-engagement patterns. The graph provides an expansive, granular, and dynamic taxonomy easily adaptable to emerging interests. The interest graph overcomes limitations of conventional taxonomies that lack depth, fail to capture niche interests, and cannot adapt to reflect evolving user preferences. The described techniques construct a rich interest graph from diverse content for improved content understanding.

Abstract: Techniques for automated tagging of visual content are described. A pairwise model is used to encode images and videos with a vision encoder, and encode keywords and phrases from an interest graph with a text encoder. Similarity layers compare these cross-modality embeddings by calculating distance in a shared embedding space. Scores indicate the association between visual features and text. A pairwise loss function brings together matched pairs while separating non-matches during training. Scores exceeding a threshold tag content with relevant keywords and phrases. The pairwise architecture relates images and text despite limited associated text. It leverages vision-to-text understanding for accurate tagging without per-class labels. Contrastive similarity techniques associate visual patterns with textual concepts. Automated tagging organizes user-generated content by topics using this scalable cross-modality approach.

Abstract: At least one device can be classified based on user activity. At least one telemetry variable with respect to time may be received for the at least one device. The at least one telemetry variable with respect to time may be used to determine an activity model for the at least one device. Based on the activity model, a probability of the at least one device belonging to a profile or to a type of user may be determined. Based on the type of user of the at least one device, a setting associated with the at least one device may be changed.

Abstract: At least one device can be classified based on user activity. At least one telemetry variable with respect to time may be received for the at least one device. The at least one telemetry variable with respect to time may be used to determine an activity model for the at least one device. Based on the activity model, a probability of the at least one device belonging to a profile or to a type of user may be determined. Based on the type of user of the at least one device, a setting associated with the at least one device may be changed.

Abstract: The present application relates to novel substituted imidazo[4,5-c]cinnolin-2-one compounds and pharmaceutically acceptable salts thereof, which selectively modulate ataxia telangiectasia mutated (“ATM”) kinase. The present application also relates to pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and to the use of the compounds and salts thereof in the treatment of ATM-associated diseases or conditions, including cancers.

Abstract: It is disclosed crystalline forms of (R)-N-(4-([1, 2, 4]triazolo [1, 5-c]pyrimidin-7-yloxy)-3-methylphenyl)-5-((3, 3-difluoro-1-methylpiperidin-4-yl)oxy)-6-methoxyquinazolin-4-amine, methods for the preparation thereof, pharmaceutical compositions comprising one or more of the crystalline forms as an active ingredient, and use of the crystalline forms in the treatment of hyperproliferative diseases.

Abstract: Provided novel compounds useful as KRAS G12D inhibitors, as well as pharmaceutical compositions comprising these compounds and methods of treatment by administration of these compounds or the pharmaceutical compositions.

Abstract: Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.

Abstract: A combined display method includes: the mobile device broadcasts a first message in response to receiving a first input, where the first message indicates that the combined display needs to be performed; the mobile device obtains a first image, where the first image includes a first display and a second display, the first display displays first information, and the second display displays second information; the mobile device sends a second message to a first electronic device, where the second message includes the first information, the second information, orientation information of the first display and the second display, a size proportion relationship between the first display and the second display, and a correspondence between the first information and the first display; and the first electronic device controls, in response to receiving the second message, a plurality of electronic devices to perform combined display.

Abstract: The specification relates to imidazo [4,5-c] cinnolin-2-one compounds and pharmaceutically acceptable salts thereof, which selectively modulate ataxia telangiectasia mutated (“ATM”) kinase. The specification also relates to pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and to the use of the compounds and salts thereof in the treatment of ATM-associated diseases or conditions, including cancers.

Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

Abstract: A power line communication-based pairing method and device for an air conditioner, and a storage medium are provided. Based on a pairing request instruction, A CCO module on an indoor side selects an STA module to be paired, in a power line network, for use as a pairing object. The CCO module sends pairing request information to the power line network. The STA module receives the pairing request information. If the STA module determines that identification information thereof exists in the pairing request information, the STA module establishes a pairing relationship with the CCO module. The STA module sends pairing feedback information to the power line network. The CCO module receives the pairing feedback information. If the CCO module determines that the identification information thereof exists in the pairing feedback information, the CCO module determines that the pairing is successful and establishes a pairing relationship with the STA module.

Abstract: Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.