Patents by Inventor Dominique Charmot

Dominique Charmot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LINEAR POLYOL STABILIZED POLYFLUOROACRYLATE COMPOSITIONS
    Publication number: 20100111891
    Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: August 22, 2009
    Publication date: May 6, 2010
    Applicant: RELYPSA, INC.
    Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
  • TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES
    Publication number: 20100104527
    Abstract: The present invention is directed to methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio.
    Type: Application
    Filed: August 22, 2009
    Publication date: April 29, 2010
    Applicant: RELYPSA, INC.
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Werner Strüver
  • Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors
    Patent number: 7666898
    Abstract: Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: February 23, 2010
    Assignee: Ilypsa, Inc.
    Inventors: Han-Ting Chang, Dominique Charmot, Tomasz Glinka, Michael James Cope, Elizabeth Goka, Jun Shao, Damien Cartigny, Shiah-yun Chen, Jerry M. Buysse
  • ANION-BINDING POLYMERS AND USES THEREOF
    Publication number: 20100029897
    Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.
    Type: Application
    Filed: May 22, 2009
    Publication date: February 4, 2010
    Applicant: Ilypsa, Inc.
    Inventors: Eric Connor, Dominique Charmot, Han-Ting Chang, Florence Roger, Gerrit Klaerner, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
  • INDOLE COMPOUNDS HAVING C4-ACIDIC SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
    Publication number: 20090318492
    Abstract: Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.
    Type: Application
    Filed: November 3, 2006
    Publication date: December 24, 2009
    Inventors: Han-Ting Chang, Dominique Charmot, Tomasz Glinka, Michael James Cope, Elizabeth Goka, Jun Shao, Shiah-yun Chen, Jerry M. Buysse
  • INDOLE COMPOUNDS HAVING C4-AMIDE SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
    Publication number: 20090306171
    Abstract: Indole and indole-related compounds according to the formula (I) or (II) optionally having additional heteroatoms, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject. Formula (I), formula (II). R4 being a moiety represented by formula (C4-II-C), R3 being a moiety represented by formula (C3-I or C3-II).
    Type: Application
    Filed: November 3, 2006
    Publication date: December 10, 2009
    Inventors: Han-Ting Chang, Dominique Charmot, Tomasz Glinka, Michael James Cope, Elizabeth Goka, Jun Shao, Shiah-yun Chen, Jerry M. Buysse
  • Pharmaceutical compositions comprising cross-linked small molecule amine polymers
    Patent number: 7608674
    Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.
    Type: Grant
    Filed: November 3, 2004
    Date of Patent: October 27, 2009
    Assignee: Ilypsa, Inc.
    Inventors: Eric Connor, Dominique Charmot, Han-Ting Chang, Florence Roger, Gerrit Klaerner, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
  • AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
    Publication number: 20090239896
    Abstract: Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject. The compounds include azaindoles of the formula below [insert FIG. 6c] in which at least one of CR4, CR5, CR6 and CR7 is replaced by N, and the groups R1-R7 are defined as in claim 1.
    Type: Application
    Filed: November 3, 2006
    Publication date: September 24, 2009
    Inventors: Han-Ting Chang, Dominique Charmot, Tomasz Glinka, Michael James Cope, Elizabeth Goka, Jun Shao, Tony Kwok-Kong Mong, Shiah-yun Chen, Jerry M. Buysse
  • Treatment of hyperphosphatemia using crosslinked small molecule amine polymers
    Patent number: 7589238
    Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: September 15, 2009
    Assignee: Ilypsa, Inc.
    Inventors: Eric Connor, Dominique Charmot, Han Ting Chang, Florence Roger, Gerrit Klaemer, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
  • METHODS FOR PREPARING CORE-SHELL COMPOSITES HAVING CROSS-LINKED SHELLS AND CORE-SHELL COMPOSITES RESULTING THEREFROM
    Publication number: 20090186093
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such core-shell composites. In particular, the invention provides core-shell particles and compositions comprising potassium binding polymers, and core-shell particles and compositions comprising sodium binding polymers, and in each case, pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are also disclosed. The compositions and methods of the invention offer improved approaches for treatment of hyperkalemia and other indications related to potassium ion homeostasis, and for treatment of hypertension and other indicates related to sodium ion homeostasis.
    Type: Application
    Filed: October 2, 2006
    Publication date: July 23, 2009
    Applicant: RELYPSA, INC.
    Inventors: Futian Liu, Han-Ting Chang, Dominique Charmot, Eric Connor, Paul Mansky, Mingjun Liu
  • Ion binding polymers and uses thereof
    Patent number: 7556799
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: July 7, 2009
    Assignee: Relypsa, Inc.
    Inventors: Dominique Charmot, Han Ting Chang, Gerrit Klaerner, Michael J. Cope, Mingjun Liu, Futian Liu, Jerry M. Buysse
  • METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL
    Publication number: 20090155370
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such core-shell composites. In particular, the invention provides core-shell particles and compositions comprising potassium binding polymers, and core-shell particles and compositions comprising sodium binding polymers, and in each case, pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are also disclosed. The compositions and methods of the invention offer improved approaches for treatment of hyperkalemia and other indications related to potassium ion homeostasis, and for treatment of hypertension and other indicates related to sodium ion homeostasis.
    Type: Application
    Filed: October 2, 2006
    Publication date: June 18, 2009
    Applicant: RELYPSA, INC.
    Inventors: Michael J. Cope, Paul Mansky, Futian Liu, Han-Ting Chang, Dominique Charmot, Eric Connor, Kalpesh Biyani, Mingjun Liu, Tony Kwok-Kong Mong, Yan Chen
  • ION BINDING COMPOSITIONS
    Publication number: 20090148533
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
    Type: Application
    Filed: September 26, 2008
    Publication date: June 11, 2009
    Applicant: Relypsa, Inc.
    Inventors: Dominique Charmot, Han-Ting Chang, Eric Connor, Mingjun Liu, Gerrit Klaerner
  • Photoresist polymers
    Patent number: 7517634
    Abstract: The present invention is directed to the preparation of photoresist polymers via living free radical polymerization techniques. Sterically bulky ester monomers are utilized as the polymerization components. Use of chain transfer agents is included in polymerization processing conditions. Cleavage of polymer terminal end groups that include a heteroatom are described.
    Type: Grant
    Filed: December 12, 2005
    Date of Patent: April 14, 2009
    Assignee: JSR Corporation
    Inventors: Didier Benoit, Adam Safir, Han-Ting Chang, Dominique Charmot, Kenji Okamoto, Isao Nishimura, Yong Wang
  • Photoresist polymer compositions
    Patent number: 7510817
    Abstract: The present invention is directed to the preparation of photoresist polymers via living free radical polymerization techniques. Sterically bulky ester monomers are utilized as the polymerization components. Use of chain transfer agents is included in polymerization processing conditions. Cleavage of polymer terminal end groups that include a heteroatom are described.
    Type: Grant
    Filed: December 12, 2005
    Date of Patent: March 31, 2009
    Assignee: JSR Corporation
    Inventors: Didier Benoit, Adam Safir, Han-Ting Chang, Dominique Charmot, Isao Nishimura, Akimasa Soyano, Kenji Okamoto, Yong Wang
  • Ion binding polymers and uses thereof
    Patent number: 7488495
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: February 10, 2009
    Assignee: Relypsa, Inc.
    Inventors: Dominique Charmot, Han Ting Chang, Gerrit Klaerner, Michael James Cope, Mingjun Liu, Futian Liu, Jerry Buysse, Eric Connor, Tony Kwok-Kong Mong, Jun Shao, Deidre Madsen
  • Home and personal care compositions comprising silicon-based lubricants
    Patent number: 7465439
    Abstract: A composition for personal, home, or laundry treatment comprising a polymer made up of one or more crosslinked rake or comb silicone copolymer segments. A process for making copolymers for use in such compositions involves hydrosilylation in the presence of a catalyst.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: December 16, 2008
    Assignee: Conopco, Inc.
    Inventors: Andrew Richard Avery, Dominique Charmot, Jean M Frechet, Damian Hajduk, Ezat Khoshdel, Mingjun Liu
  • Pharmaceutical compositions comprising crosslinked polyamine polymers
    Patent number: 7459502
    Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: December 2, 2008
    Assignee: Ilypsa, Inc.
    Inventors: Eric Connor, Dominique Charmot, Han Ting Chang, Florence Roger, Gerrit Klearner, Son Hoai Nguyen
  • Crosslinked amine polymers
    Patent number: 7449605
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked amine polymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases and hyperphosphatemia.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: November 11, 2008
    Assignee: Ilypsa, Inc.
    Inventors: Han Ting Chang, Dominique Charmot, Eric Connor, Florence Roger
  • Crosslinked amine polymers
    Patent number: RE41316
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked amine polymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases and hyperphosphatemia.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: May 4, 2010
    Inventors: Han Ting Chang, Dominique Charmot, Eric Connor, Florence Roger