Patents by Inventor Dorte Strobaek

Dorte Strobaek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS
    Publication number: 20100087496
    Abstract: This invention relates to novel cinnamic amide derivatives that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of ion channels.
    Type: Application
    Filed: December 17, 2007
    Publication date: April 8, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Joachim Demnitz, Thomas Diness Jensen, Palle Christophersen, David Spencer Jones, Elsebet Ostergaard Nielsen, Dorte Strobaek, Lars Siim Madsen
  • NOVEL 2-AMINIO-PYRIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100056584
    Abstract: This invention relates to novel 2-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: November 12, 2007
    Publication date: March 4, 2010
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm, Palle Christophersen
  • 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
    Publication number: 20100035951
    Abstract: This invention relates to 2-amino benzimidazole derivatives of Formula 1a or 1b: which are useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: July 5, 2007
    Publication date: February 11, 2010
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL 4-AMINO-PYRIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100035924
    Abstract: This invention relates to novel 4-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: November 13, 2007
    Publication date: February 11, 2010
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • Novel Quinazoline Derivatives and Their Medical Use
    Publication number: 20090291973
    Abstract: This invention relates to novel quinazoline derivatives having medical utility, to use of the quinazoline derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the quinazoline derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: November 17, 2006
    Publication date: November 26, 2009
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Lene Teuber, Tino Dyhring, Dorte Strøbæk, Carsten Jessen
  • COMBINATIONS OF MONOAMINE REUPTAKE INHIBITORS AND POTASSIUM CHANNEL ACTIVATORS
    Publication number: 20090239880
    Abstract: This invention provides pharmaceutical compositions comprising therapeutically effective amounts of a monoamine reuptake inhibitor and an SK inhibitor. In another aspect the invention provides novel benzoimidazole derivatives for use according to the invention.
    Type: Application
    Filed: July 2, 2007
    Publication date: September 24, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen, John Paul Redrobe
  • Novel Pyrimidine-2,4-Diamine Derivatives and their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090124645
    Abstract: This invention relates to novel pyrimidine-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: October 13, 2006
    Publication date: May 14, 2009
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL GUANIDINE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090099208
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 22, 2007
    Publication date: April 16, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels
    Publication number: 20090076106
    Abstract: This invention relates to novel 2-(phenylamino)benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 21, 2006
    Publication date: March 19, 2009
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Novel Quinazoline-2,4-Diamine Derivatives and Their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090048278
    Abstract: This invention relates to novel quinazoline-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 6, 2006
    Publication date: February 19, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090036473
    Abstract: This invention relates to novel quinazolinone derivatives having medical utility, to use of the quinazolinone derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the quinazolinone derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: March 9, 2007
    Publication date: February 5, 2009
    Inventors: William Dalby Brown, Carsten Jessen, Joachim Demnitz, Tino Dyhring, Dorte Strobaek
  • Novel 2-Amino Benzimidazole Derivatives and Their Use As Modulators Of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20080200529
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: January 10, 2006
    Publication date: August 21, 2008
    Applicant: NEURO SEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Publication number: 20070197618
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: August 3, 2005
    Publication date: August 23, 2007
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Johansen, Karin Nielsen, Palle Christophersen
  • Erg channel openers for the treatment of cardiac arrhythmias
    Publication number: 20060281794
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Application
    Filed: September 6, 2004
    Publication date: December 14, 2006
    Inventors: Soren Olesen, Morten Grunnet, Palle Christophersen, Dorte Strobaek, Joachim Demnitz, Rie Hansen
  • Ion channel modulating agents
    Patent number: 7012146
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SK Ca, IK Ca and BK Ca channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, for methods of therapy, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: March 14, 2006
    Assignee: Poseidon Pharmaceuticals A/S
    Inventors: Bo Skaaning Jensen, Dorte Strobaek, Palle Christophersen, Lene Teuber, Jurgen Beyer
  • Use of isatin derivatives as ion channel activating agents
    Patent number: 6969729
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: November 29, 2005
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jørgensen, Philip K. Ahring, Palle Christophersen, Dorte Strøbaek, Lene Teuber, Søren Peter Olesen
  • Potassium channel blocking agents
    Patent number: 6878701
    Abstract: Compounds of Formula I: wherein A and B are linking groups; R1, R2, R3 and R4 are defined moieties. An exemplary compound is: These compounds function as potassium channel blocking agents, and can be used in a wide variety of pharmaceutical compositions for the treatment of a wide variety of diseases.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: April 12, 2005
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Soren Peter Olesen, Dorte Strobaek
  • Ion channel modulating agents
    Patent number: 6759422
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: July 6, 2004
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents
    Publication number: 20040029937
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: July 1, 2003
    Publication date: February 12, 2004
    Applicant: NEUROSEARCH A/S.
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators
    Publication number: 20030181507
    Abstract: The present invention relates to a novel method of treating of pain or anxiety, using compounds that modulate KCNQ potassium channels and currents.
    Type: Application
    Filed: February 24, 2003
    Publication date: September 25, 2003
    Inventors: Bo Skaaning Jensen, Rikke Schroder, Dorte Strobaek, Soren Peter Olesen