Patents by Inventor Dorte Strobaek

Dorte Strobaek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ion channel modulating agents comprising novel benzimidazolone derivatives
    Patent number: 6624186
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: September 23, 2003
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20030114513
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 19, 2003
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Bis(benzimidazole) derivatives serving as potassium blocking agents
    Patent number: 6569880
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: May 27, 2003
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbæk
  • Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
    Patent number: 6545028
    Abstract: This invention relates to treatment or alleviation of a disease, condition or disorder selected from inflammatory bowel disease, Chron's disease, colitis ulcerosa, Coeliac disease, dermatitis herpetiformis, dermatomyositis, enteritis allergia, erytherma nodosum leprosum, ileitis regionalis, psoriasis, purpura, scleritis or scleroderma by administering to a living body certain imidazole, triazole, or 1,4-dihydropyridine derivatives.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: April 8, 2003
    Assignee: NeuroSearch A/S
    Inventors: Bo S. Jensen, Søren-Peter Olsen, Tino D. Jørgensen, Dorte Strøbæk, Palle Christophersen, Niels Ødum
  • Use of ion channel modulating agents
    Patent number: 6525043
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: February 25, 2003
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20030008906
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 9, 2003
    Applicant: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20020169203
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SK Ca, IK Ca and BK Ca channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, for methods of therapy, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: May 15, 2001
    Publication date: November 14, 2002
    Inventors: Bo Skaaning Jensen, Dorte Strobaek, Palle Christophersen, Lene Teuber, Jurgen Beyer
  • Ion channel modulating agents
    Patent number: 6458846
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of oxime derivatives represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: October 1, 2002
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Palle Christophersen, Dorte Strobaek, Lene Teuber
  • Potassium channel blocking agents
    Publication number: 20020137784
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: February 28, 2002
    Publication date: September 26, 2002
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Soren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strobaek
  • Potassium channel blocking agents
    Publication number: 20020128279
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: December 28, 2001
    Publication date: September 12, 2002
    Inventors: Lene Teuber, Soren Peter Olesen, Dorte Strobaek
  • Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
    Publication number: 20020119989
    Abstract: The present invention relates to chemical compounds having inhibitory activity on an intermediate conductance Ca 2+ activated potassium channel (IK Ca), and the use of such compounds for the treatment or alleviation of diseases or conditions relating to immune dysfunction. Moreover, the invention relates to a method of screening a chemical compound for inhibitory activity on an intermediate conductance Ca 2+ activated potassium channel (IK Ca).
    Type: Application
    Filed: April 14, 2000
    Publication date: August 29, 2002
    Inventors: Bo S. Jensen, Soren-Peter Olsen, Tino D. Jorgensen, Dorte Strobaek, Palle Christophersen
  • Ion channel modulating agents
    Publication number: 20020065315
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general Formula (I) and a pharmaceutically acceptable salt or an oxide or a hydrate thereof, that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Use of ion channel modulating agents
    Publication number: 20020065266
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: October 25, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20020061914
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 23, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20020058700
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of oxime derivatives represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: May 15, 2001
    Publication date: May 16, 2002
    Inventors: Bo Skaaning Jensen, Palle Christophersen, Dorte Strobaek, Lene Teuber
  • Benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents
    Publication number: 20020055526
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: May 15, 2001
    Publication date: May 9, 2002
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Potassium channel blocking agents
    Patent number: 6380180
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: April 30, 2002
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbaek
  • Potassium channel blocking agents
    Publication number: 20020049246
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: December 29, 2000
    Publication date: April 25, 2002
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Soren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strobaek
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20020016354
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: May 15, 2001
    Publication date: February 7, 2002
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Bis (benzimidazole) derivatives serving as potassium blocking agents
    Patent number: 6194447
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: February 27, 2001
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbæk