Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, Y3, Y4 R1, R2, R4a, R4b, R5a, R5b, R6a and R6b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.

Abstract: According to various embodiments, techniques and mechanisms described herein facilitate the editing of computer programming tags associated with a website. A user interface displaying a representation of a website may be presented on a display screen. The representation may include a plurality of webpage identifiers that each identifies a respective webpage associated with the website. The representation may also include a plurality of active tag indicators that are each associated with a respective one of the webpages. Each active tag indicator may identify a respective portion of computer programming code included in the respective webpage with which the active tag indicator is associated. User input indicating an editing action to be performed with respect to one or more of the computer programming code portions may be received, and a message identifying the editing action may be transmitted via a communications interface.

Abstract: A locomotive engine control system includes one or more processors operably connected to fuel supply devices. The fuel supply devices are configured to supply fuel into different corresponding cylinders of an engine. The one or more processors are configured to monitor a fuel quantity injected into the cylinders of the engine before and after communication of an overfuel control signal. The overfuel control signal commands the fuel supply device corresponding to a first cylinder of the cylinders to supply excess fuel into the first cylinder. Responsive to the fuel quantity that is monitored not decreasing after the communication of the overfuel control signal, the one or more processors are configured to determine that the fuel supply device corresponding to the first cylinder is defective, and may generate one or more control signals indicative of the fuel supply device corresponding to the first cylinder being defective.

Abstract: A computing device and method for use in enabling contextual ink annotation in a mapping interface are disclosed. In one aspect, the computing method may include receiving a map view request to render a map view of map data based upon a current map rendering context, determining that a previously created virtual ink annotation is associated with a location within the map view, the virtual ink annotation having a previous map rendering context captured at a time of creation of the virtual ink annotation, and comparing the current map rendering context to the previous map rendering context associated with the virtual ink annotation. The method may further include, based on a result of the comparison, controlling display of the virtual ink annotation in a rendered map view.

Abstract: According to various embodiments, techniques and mechanisms described herein facilitate the storage of an image of a rendered webpage on a storage medium. A first message including a request for a webpage may be transmitted to a web server via a communications interface. The webpage request may generate an advertising opportunity bid request for bids to place an advertisement on the requested webpage. A second message to place a bid on the generated advertising opportunity bid request may be transmitted. Information for rendering the webpage is received in response to the webpage request, and an image of the rendered webpage may be stored on a storage medium.

Abstract: Systems, methods, and software can be used to share content. In some aspect, an enterprise mobility management (EMM) server receives a command for provisioning a user for an enterprise service at an identity provider (IDP). The EMM server sends a user provisioning request to the IDP. The user provisioning request includes a user identity attribute and a user entitlement attribute, the user identity attribute identifies the user, and the user entitlement attribute indicates an access level associated with the user for the enterprise service. The EMM server receives a user provisioning response from the IDP. The user provisioning response indicates that the user is provisioned at the IDP for the enterprise service.

Abstract: A computer-implemented method according to one embodiment includes identifying a plurality of documents associated with a predetermined subject, where each of the plurality of documents contains textual data, analyzing the textual data of each of the plurality of documents to identify one or more categories within the plurality of the documents, and returning the one or more categories identified within the plurality of the documents.

Abstract: Systems and methods for providing a document are described. In one described method, a document comprising a portion selected by a first member of a social network is hoisted for the first member. The portion is dynamically updated with content. An audience criterion for the portion and a type of relationship between the first member and a second member of the social network are identified. If the type of relationship between the first member and the second member satisfies the audience criterion, the second member is provided access to at least the portion.

Abstract: Structural devices for energy dissipation can be designed to provide asymmetrical responses to cyclic axial loading. The energy dissipation devices can be designed to provide a known or predictable response to tensile loading, along with a different known or predictable response to compressive loading. The devices may include a filament which bears a portion of both tensile and compressive loads and a bracing device which provides lateral support to the filament to prevent buckling. Interlocks or a similar restraining mechanism can be used to resist part of either a compressive or tensile load. These components can be configured in such a manner as to provide an asymmetric response.

Abstract: Embodiments provide a system and method for semantic distance calculation. The method can involve receiving a plurality of documents having a set of subjects extracted through the use of latent dirichlet allocation; for each document in the plurality of documents, generating a classification list comprising a ranking of the one or more subjects based on the relevance of each subject to the document; for each classification list, calculating the semantic distance between each subject present on the classification list; aggregating the plurality of classification lists; and creating a distance matrix containing the relative semantic distances between each member of the set of subjects.

Abstract: A method and apparatus provides for user authentication. In an example, the method and apparatus includes establishing a very short range wireless communication link between the first apparatus and the second apparatus and authenticating a user of the first apparatus by the second apparatus directly using a different and short range peer to peer wireless communication link between the first apparatus and the second apparatus in response to establishing the very short range wireless communication link.

Abstract: Embodiments provide a system and method for semantic distance calculation. The method can involve ingesting a plurality of documents; extracting a set of subjects from the plurality of documents using latent dirichlet allocation; for each document in the plurality of documents, generating a classification list comprising a ranking of the one or more subjects based on the relevance of each subject to the document; for each classification list, calculating the semantic distance between each subject present on the classification list; aggregating the plurality of classification lists; and creating a distance matrix containing the relative semantic distances between each member of the set of subjects.

Abstract: Systems and methods for providing a document are described. In one described method, a document comprising a portion selected by a first member of a social network is hosted for the first member. The portion is dynamically updated with content. An audience criterion for the portion and a type of relationship between the first member and a second member of the social network are identified. If the type of relationship between the first member and the second member satisfies the audience criterion, the second member is provided access to at least the portion.

Abstract: Various embodiments for failure recovery in a computing environment following a data restoration are provided. A catalog locate is performed for each of a plurality of data sets on a base catalog structure (BCS), identifying a plurality of BCS entries. If a first BCS entry is cataloged incorrectly, the first BCS entry is designated to be re-cataloged. The plurality of BCS entries is compared with a plurality of volume table of contents and a plurality of VSAM volume data set (VTOC/VVDS) entries. If a second BCS entry found in the plurality of BCS entries is not found in the plurality of VTOC/VVDS entries, and the second BCS entry indicates that a data set associated with the second BCS entry is located on a volume, an attempt is made to vary on the volume. If the volume cannot be varied on, a request is created to restore the volume.

Abstract: A high performance sealant for repairing punctures in tires includes a highly filtered natural rubber latex, an ultra-fine inorganic powder, a polyamide suspension, and an antifreeze agent that includes water and at least one of ethylene glycol and propylene glycol. The high performance sealant can readily pass through a valve stem of a tire without removing the core and seal, and provides a strong and durable sealing of the puncture.

Abstract: A method, computer program product, and computing system for receiving content from a third-party; processing the content to predict the disclosure of sensitive information; and obscuring the sensitive information from a platform user.

Abstract: A vehicle includes an engine and alternator having a field coil and a plurality of output windings, a field current controller configured to receive an AC input and convert the AC input into a regulated DC output that is supplied to the field coil of the alternator, and a controller configured to monitor at least one operating parameter of the field current controller and to compare a monitored value of the at least one operating parameter to a threshold range.

Abstract: An apparatus, which may be a tillage apparatus, is disclosed that may have a flexible frame. The frame may be made from open members. The frame may support ground engagers and may be supported on wheel assemblies. The ground engagers may be connected to a spring trip mechanism. The ground engagers may be mounted to open members of the frame with a clamping style mechanism. The clamp mechanism may include wedge devices. The frame may be lowered and raised relative to wheels of the wheel assemblies with a lift mechanism. One row of ground engagers may be raised or lowered relative to the frame independent of another row of ground engagers. An anti-skid or skew control system may be employed in association with the independent height adjustment of one row of ground engagers. A system may be provided to maintain and control the height of a tow hitch forming part of the apparatus.

Abstract: A method and apparatus provides for user authentication. In an example, the method and apparatus includes receiving a selected signal strength for smart card emulation authentication. The method and apparatus also includes receiving a signal from a portable wireless device radio transceiver. The method also includes measuring the signal strength of the signal. The method and apparatus also includes, if the signal is at or above the selected signal strength, transmitting one or more signals to the portable radio device radio transceiver requesting user authentication, and if the signal is not at or above a selected signal strength, refusing a request to authenticate by the portable radio device radio transceiver. The method and apparatus also includes receiving one or more authentication response signals from the portable radio device in response to the request for user authentication, the one or more response signals including at least authentication information unique to a user.