Abstract: A faucet assembly includes a faucet body having a mounting axis in a direction the faucet body projects from a mounting point. The assembly further includes a valve housing projecting from the faucet body and a valve disposed in the valve housing. The valve is configured to rotate about an axis parallel to and offset from the mounting axis.

Abstract: Embodiments are directed to a tie layer composition comprising functionalized polyethylene, styrene block copolymer, base polyethylene, and antioxidant co-stabilizers, wherein the antioxidant co-stabilizers comprise at least one oxygen scavenger, at least one peroxy free radical scavenger, and at least one alkyl free radical scavenger. Further embodiments are directed to multilayer films or sheets which include the tie layer composition.

Abstract: Cancer cells with defects in DNA repair are highly susceptible to DNA-damaging agents, but delivery of therapeutic agents into cell nuclei can be challenging. A sub-set of autoantibodies having nucleolytic activity are capable of nuclear penetration. These antibodies can be used as therapeutic agents targeted towards DNA repair-deficient malignancies.

Abstract: A system for performing exothermic operations or oxygen delivery uses a rod and handle configuration to create a flowpath of oxygen. The rod includes cables having stainless steel fibers that burn using the oxygen within a hollow center area. While burning, the rod cuts through material. A sheath covers the covers to contain the gases and prevent unraveling of the cables. The handle attaches to the rod and provides control of the flow of oxygen to the rod. A manifold fixing in place bottles of oxygen connects to the handle and can be fixed to provide different mixtures from different bottles. The rod is disconnected when needed to fix a mask thereto for delivering breathable oxygen to a patient.

Abstract: A pressurized metered dose dispenser (100) for dispensing an aerosol formulation comprising particles of a medicament suspended in liquefied propellant, optionally in combination with one or more excipients, the dispenser comprising an aerosol container (1) equipped with a metered dose valve (10), where a formulation chamber is defined in part by the internal walls of the container, and wherein the dispenser further comprises a porous, fluid permeable, particulate semi-permeable body (40) located within the formulation chamber adjacent to the metered dose valve.

Abstract: Implantable medical devices including interconnections having strain-relief structure. The interconnections can take the form of flexible circuits. Strain relief gaps and shapes are integrated in the interconnections to relieve forces in each of three dimensions. In some examples, the region of an interconnection which couples with a component of the implantable medical device is separated by a strain relief gap from a connection to a second component and/or a location where the flex bends around a corner.

Abstract: A high-pressure passthrough apparatus and protective suit having a high-pressure passthrough is provided. A high-pressure passthrough having a penetrator body is connected to a protective suit, wherein a first half of the penetrator body is positioned exterior of the protective suit and a second half of the penetrator body is positioned interior of the suit. A high-pressure passthrough valve is positioned on the second half of the penetrator body, wherein high-pressured air is supplied to an interior space of the protective suit. Releasing the quantity of high-pressure air to the interior of the protective suit with the high-pressure passthrough valve may act to cool the interior of the protective suit.

Abstract: A method for controlling touchless operation of a faucet that includes turning on a sensor of the faucet in response to receiving a signal that a mechanical valve of the faucet is in an open position, wherein the mechanical valve is movable between the open position and a closed position; shifting an electronic valve of the faucet from a closed state, in which a fluid does not flow from the faucet, to an open state, in which the fluid is configured to flow from the faucet, in response to a first interruption of a field of detection of the sensor; and shifting the electronic valve to the closed state in response to a second interruption of the field of detection of the sensor, so long as the second interruption follows the first interruption within a predetermined period of time.

Abstract: Embodiments disclosed herein related to superalloy compositions and applications using the same. The superalloy compositions disclosed herein including at least one ternary intermelallic compound having a general chemical composition of AZ[BXCY]. Base element A is selected from the group consisting of cobalt, iron, and nickel; and element B and element C are independently selected from different members of a group consisting 40 elements of the periodic table. Base element A, element B, and clement C are each different elements. Z is about 2.1 to about 3.9. X and Y are about 0.1 to about 1.9. Additionally, the at least one ternary intermelallic compound of each of the superalloy compositions exhibits the face-centered cubic structure L12. The at least one ternary intermetallic compound of each of the ternary superalloy compositions may exhibit a theoretical formation enthalpy and a decomposition energy less than Co3[Al, W].

Abstract: An integrated manifold system is disclosed that combines in a single, compact, unitary assembly a one-piece, machined manifold for connecting air supply cylinders with a first stage regulator and recharge port. The manifold body has at least one bottle port configured to removably receive a bottle of pressurized air, a first stage regulator chamber, a quick disconnect fitting port, an air channel in fluid communication with the at least one bottle port and the first stage regulator chamber, and an outlet channel in fluid communication with the first stage regulator chamber.

Abstract: Cancer cells with defects in DNA repair are highly susceptible to DNA-damaging agents, but delivery of therapeutic agents into cell nuclei can be challenging. A sub-set of autoantibodies having nucleolytic activity are capable of nuclear penetration. These antibodies can be used as therapeutic agents targeted towards DNA repair-deficient malignancies.

Abstract: Implantable medical devices including interconnections having strain-relief structure. The interconnections can take the form of flexible circuits. Strain relief gaps and shapes are integrated in the interconnections to relieve forces in each of three dimensions. In some examples, the region of an interconnection which couples with a component of the implantable medical device is separated by a strain relief gap from a connection to a second component and/or a location where the flex bends around a corner.

Abstract: The present invention provide for solutions of a defined composition useful in a staining protocol, such as a hematoxylin and eosin staining protocol, when used at certain points of the staining protocol. The formulations of these defined solutions are such that carry-over of the solutions will not negatively impact, or preferably, will stabilize or favorably modify staining reagent solutions coming in contact with the solutions. In certain embodiments of the invention, solutions are buffered to maintain a specific pH that when carried-over—such as carried-over into hematoxylin—will not significantly influence the pH of the next staining reagent.

Abstract: The present disclosure relates to a system of modular functional blocks that may be used to facilitate easy assembly of a welding head assembly in any one of a wide variety of configurations to allow for distribution of welding wire, gas, cooling fluid and other media throughout an interconnected assembly of the modular functional blocks. As such, the modular functional blocks can be mixed and matched into any desired configuration as needed depending on the welding process being undertaken. The modular functional blocks may be in the form of one or more different welding wire delivery blocks, gas delivery blocks, cooling water delivery blocks, shim plates, end plates, shield cup, cover plates, insulating plates, etc.

Abstract: System and techniques for a virtual detent bezel device are described herein, a configuration that specifies a detent pattern and an output pattern corresponding to the detent pattern may be received receiving by the virtual detent bezel device. A physical portion of the virtual detent bezel device may sense a rotational action of a user interacting with a physical portion of the virtual detent bezel device. The rotational action may be compared to a present rotational position to determine a rotational change. The rotational change may be thresholded against the detent pattern to determine that a detent is crossed. A haptic feedback device may be activated in response to determining that the detent is crossed. A portion of the output pattern that corresponds to the detent that is crossed may be output by the virtual detent bezel device.

Abstract: A system for performing exothermic operations or oxygen delivery uses a rod and handle configuration to create a flowpath of oxygen. The rod includes cables having stainless steel fibers that burn using the oxygen within a hollow center area. While burning, the rod cuts through material. A sheath covers the covers to contain the gases and prevent unraveling of the cables. The handle attaches to the rod and provides control of the flow of oxygen to the rod. A manifold fixing in place bottles of oxygen connects to the handle and can be fixed to provide different mixtures from different bottles. The rod is disconnected when needed to fix a mask thereto for delivering breathable oxygen to a patient.

Abstract: It has been established that cancer cells with oncogenic mutants in the small GTPase K-Ras are susceptible to antibodies that bind intracellular guanosine, but delivery of antibodies into cells can be challenging. A subset of lupus autoantibodies is associated with anti-guanosine activity, and is capable of cellular penetration. These antibodies have potential as therapeutic agents targeted towards K-Ras associated malignancies.

Abstract: A faucet assembly includes a valve housing having a first side defining first and second openings, the second opening configured to receive a valve. The valve housing further includes a second side defining a third opening configured to receive at least one fluid inlet line and at least one fluid outlet line therethrough. The assembly further includes a cap configured to cover at least a portion of the third opening.

Abstract: The invention provides for a fusion protein comprising a 3E10 Fv joined to a Hsp-70, Hsp-27, Hsp-90 or GRP-78 or portion thereof, and optionally, the 3E10 Fv comprising an amino acid sequence AGIH at its amino terminus.

Abstract: A fitting for a faucet handle includes a body having an interior wall disposed within the body, the interior wall having a plurality of apertures. Each aperture has at least a first opening and a second opening fluidly connected by a channel, and the first opening is angularly offset relative to the second opening.