Abstract: A drill bit and method for normalizing bone is provided. The drill bit has a non-round drill bit core that is adapted to cut hard bone and to not cut soft bone. The drill bit has a cutting edge which may be positioned within a compression zone of the non-round drill bit core. The rotational speed of the drill bit and the profile of the drill bit core are tuned so that hard bone recovers into a cutting zone defined by the cutting edge while soft bone remains outside of the cutting zone. The insertion torque of the drill bit can be measured to determine when the normalization is adequate.

Abstract: A dental implant (1), in particular for insertion into bone tissue of a patient, comprising: a core body (2) having an apical end (4), a coronal end (6), and an outer surface (8) extending along a longitudinal direction between said apical end (4) and said coronal end (6); and at least one thread (12) located on at least a threaded portion of said outer surface (8), should have superior properties regarding primary and secondary stability.

Abstract: A dental implant (1), in particular for insertion into bone tissue of a patient, comprising: a core body (2) having an apical end (4), a coronal end (6), and an outer surface (8) extending along a longitudinal direction between said apical end (4) and said coronal end (6); and at least one thread (12) located on at least a threaded portion of said outer surface (8), should have superior properties regarding primary and secondary stability.

Abstract: Techniques are disclosed for processing a workflow campaign. In some embodiments, a message processing service receives a first message that corresponds to a user arriving at a first node of the workflow campaign from a first message queue. The message processing service causes one or more actions associated with the first node to be performed with respect to the user. In addition, the message processing service determines that the first user should be progressed from the first node to a second node of the workflow campaign. The message processing service generates a second message that corresponds to the user arriving at the second node and determines a second message queue that is associated with the second node. The message processing service progresses the user from the first node to the second node by transmitting the second message to the second message queue.

Abstract: A drill bit and method for normalizing bone is provided. The drill bit has a non-round drill bit core that is adapted to cut hard bone and to not cut soft bone. The drill bit has a cutting edge which may be positioned within a compression zone of the non-round drill bit core. The rotational speed of the drill bit and the profile of the drill bit core are tuned so that hard bone recovers into a cutting zone defined by the cutting edge while soft bone remains outside of the cutting zone. The insertion torque of the drill bit can be measured to determine when the normalization is adequate.

Abstract: A drill bit and method for normalizing bone is provided. The drill bit has a non-round drill bit core that is adapted to cut hard bone and to not cut soft bone. The drill bit has a cutting edge which may be positioned within a compression zone of the non-round drill bit core. The rotational speed of the drill bit and the profile of the drill bit core are tuned so that hard bone recovers into a cutting zone defined by the cutting edge while soft bone remains outside of the cutting zone. The insertion torque of the drill bit can be measured to determine when the normalization is adequate.

Abstract: The present invention relates to use of expression vectors and other compounds in methods to disrupt the LInker of Nucleoskeleton and Cytoskeleton (LINC) complex, uncoupling the nucleus from its linkage to the cytoskeleton, resulting in amelioration of diseases caused by one or more Lmna mutations, so-called laminopathies. More particularly, the invention relates to the expression of dominant negative SUN domain protein and/or dominant negative KASH domain protein to disrupt, for example, the LINC complex in cardiomyocytes for suppressing disease progression in dilated cardiomyopathy (DCM).

Abstract: Method and system for implanting an implant (20, 130) in a bone (12) is provided. An osteotomy (10) having a first transverse cross-sectional shape is formed in a bone (12). An implant (20, 130) having a second transverse cross-sectional shape is inserted into the osteotomy (10), the transverse cross-sectional shape of the implant (20, 130) being different from the transverse cross-sectional shape of the osteotomy (10). The invention further relates to a preparation tool (100) for forming a non-circular cavity (10) in bone tissue (12). The preparation tool (100) comprises a proximal portion (102) and a distal portion (104). The distal portion (104) has a main body (106) and at least one bone removing element (108). At least apart of the at least one bone removing element (108) extends radially outward beyond an outer circumference of the main body (106). Moreover, the invention relates to a kit comprising the preparation tool (100) and an implant (130), such as a dental implant.

Abstract: A drill bit and method for normalizing bone is provided. The drill bit has a non-round drill bit core that is adapted to cut hard bone and to not cut soft bone. The drill bit has a cutting edge which may be positioned within a compression zone of the non-round drill bit core. The rotational speed of the drill bit and the profile of the drill bit core are tuned so that hard bone recovers into a cutting zone defined by the cutting edge while soft bone remains outside of the cutting zone. The insertion torque of the drill bit can be measured to determine when the normalization is adequate.

Abstract: A dental implant (1), in particular for insertion into bone tissue of a patient, comprising: a core body (2) having an apical end (4), a coronal end (6), and an outer surface (8) extending along a longitudinal direction between said apical end (4) and said coronal end (6); and at least one thread (12) located on at least a threaded portion of said outer surface (8), should have superior properties regarding primary and secondary stability.

Abstract: A decellularized small particle tissue derived from blood-laden tissue which has been decellularized at an acid pH in the presence of blood to remove at least a portion of the cellular material therefrom. The product contains conserved beneficial proteins originally present in the blood-laden starting tissue such as fibronectin, laminin, and elastin and comprises particle sizes in the range from 200 microns to 10 Kilo Daltons. A recycling method of filtration is taught to produce various forms of the product.

Abstract: A gas cluster ion beam (GCIB) etching method for adjusting a fin height in finFET devices is described. The method includes providing a substrate having a fin structure and a gap-fill material layer completely overlying the fin structure and filling the regions between each fin of the fin structure, wherein each fin includes a cap layer formed on a top surface thereof, and planarizing the gap-fill material layer until the cap layer is exposed on at least one fin of the fin structure. Additionally, the method includes setting a target fin height for the fin structure, wherein the fin height measured from an interface between the cap layer and the fin structure, and exposing the substrate to a GCIB and recessing the gap-fill material layer relative to the cap layer until the target fin height is substantially achieved.

Abstract: A gas cluster ion beam (GCIB) etching method for adjusting a fin height in finFET devices is described. The method includes providing a substrate having a fin structure and a gap-fill material layer completely overlying the fin structure and filling the regions between each fin of the fin structure, wherein each fin includes a cap layer formed on a top surface thereof, and planarizing the gap-fill material layer until the cap layer is exposed on at least one fin of the fin structure. Additionally, the method includes setting a target fin height for the fin structure, wherein the fin height measured from an interface between the cap layer and the fin structure, and exposing the substrate to a GCIB and recessing the gap-fill material layer relative to the cap layer until the target fin height is substantially achieved.

Abstract: A protection circuit for an alternative energy source comprises a primary path including an isolation element, e.g., diode or transistor, to prevent current backflow into the alternative energy source from the power device. A low resistance bypass path around the isolation element is also provided. In a protection mode, the bypass path is opened so current must flow through the primary path. In a bypass mode, the bypass path is closed to provide a low resistance path for current to flow from the alternative energy source to the power device.

Abstract: An on-chip decoupling capacitor (106) and method of fabrication. The decoupling capacitor (106) is integrated at the top metal interconnect level (104) and includes surface protection cladding (109) for the copper metal (104b) of the top metal interconnect.

Abstract: A process for producing a decellularized small particle tissue which involves selecting an appropriate tissue starting material from which a decellularized small particle tissue is desired to be prepared, treating the tissue with a decellularizing agent at an acid pH to remove at least a portion of the cellular material therefrom and to yield a product comprising a liquid component and a solid component, subjecting the liquid component and the solid component to a plurality of filters, F1 through Fn, wherein n may be 2, or an integer higher than 2, wherein the pore sizes of the filter F1 through Fn range from 200 microns to 10 Kilo Daltons, yielding filtrates and retentates, recycling either of said filtrates or said retentates or both, either separately or together, to any of steps b) or c) or both, at least one time, and isolating a decellularized small particle tissue from any of steps of the process. Both the product and process are novel.

Abstract: A process for producing a decellularized small particle tissue which involves selecting an appropriate tissue starting material from which a decellularized small particle tissue is desired to be prepared, treating the tissue with a decellularizing agent at an acid pH to remove at least a portion of the cellular material therefrom and to yield a product comprising a liquid component and a solid component, subjecting the liquid component and the solid component to a plurality of filters, F1 through Fn, wherein n may be 2, or an integer higher than 2, wherein the pore sizes of the filter F1 through Fn range from 200 microns to 10 Kilo Daltons, yielding filtrates and resonates, recycling either of said filtrates or said retentates or both, either separately or together, to any of steps b) or c) or both, at least one time, and isolating a decellularized small particle tissue from any of steps of the process. Both the product and process are novel.

Abstract: A method for controlling a resistive property or conductive property in a resistive element using a gas cluster ion beam (GCIB) is described. In one embodiment, the method may include controlling a resistive switching behavior in a resistive switching random-access memory device using a gas cluster ion beam (GCIB).

Abstract: A method of preparing a thin film on a substrate is described. The method comprises forming an ultra-thin hermetic film over a portion of a substrate using a gas cluster ion beam (GCIB), wherein the ultra-thin hermetic film has a thickness less than approximately 5 nm. The method further comprises providing a substrate in a reduced-pressure environment, and generating a GCIB in the reduced-pressure environment from a pressurized gas mixture. A beam acceleration potential and a beam dose are selected to achieve a thickness of the thin film less than about 5 nanometers (nm). The GCIB is accelerated according to the beam acceleration potential, and the accelerated GCIB is irradiated onto at least a portion of the substrate according to the beam dose. By doing so, the thin film is formed on the at least a portion of the substrate to achieve the thickness desired.

Abstract: Disclosed is a method of fabricating an integrated circuit comprising patterning a dielectric layer to form a hole having a sidewall and a bottom. The hole can expose an underlying material of an electrically conducting material. The method also includes exposing the sidewall and the exposed underlying material to a plasma etch, depositing a barrier layer on the bottom and the sidewall of the hole after the plasma etch clean, forming a counter-sunk cone in the underlying material by etching through the barrier layer at the bottom of the hole into the conducting metal underneath, flash depositing a thin layer of the barrier material into the hole, and finally depositing a metal seed layer in the hole covering the sidewalls and the bottom of the hole including the cone at the bottom. The hole is finally filled by depositing a metal layer in the hole.