Abstract: A software artifact is scored for a user. Metadata associated with an artifact about project activity of how active an artifact project is to which the artifact belongs, a security risk indicated in the metadata of the artifact, or a license indicated in the metadata of the artifact, is collected from a software repository. A weighting of the artifact alone is determined from the metadata associated with the artifact that indicates desirability of the project activity, the security risk, or the license. The metadata associated with the artifact is compared to appropriateness with a metadata of a user project to which the user belongs as indicated by a profile of the user, so as to provide a score considering the determined weighting of the artifact and a appropriateness of the artifact for the user with respect to an intended use of the artifact by the user.

Abstract: In one aspect, the present invention provides a housing system for conducting high throughput animal experiments. The housing system includes a home cage, at least one rotatable turnstile enclosed by housing to form two or more isolation chambers, a means for animal identification, and one or more action stations functionally coupled to one or more isolation chambers. The turnstile includes a plurality of one or more separation members rotatable about a vertical axis, each isolation chamber bounded by one or more separation members. The action stations contain one or more devices facilitating completion of at least one animal-directed or experimentor-initiated action. In a preferred embodiment, the home cage is sufficiently sized to house a plurality of small animals, such as mice. Tunnel passageways may be connected to the home cage, including one or more tunnel passageways containing a rotatable turnstile.

Abstract: Embodiments of the present invention comprise an apparatus for laser marking individual objects with indicia at a marking station wherein a predetermined window exists during which each object can be marked as the objects are conveyed along at least one path at a predetermined speed, the apparatus comprising, at least first and second lasers positioned adjacent one or more paths configured to direct a laser beam onto the objects to mark the same with indicia as the objects pass through the marking station, with each of the first and second lasers marking alternate following objects as they pass through the marking station.

Abstract: An inkjet printhead (10) has at least one electrode, with exposed metal region(s) (16) of the electrode surface having a coating of inert metal, In use of the printhead, the inert metal coating functions to protect the underlying metal surface of the electrode, and in particular protects the electrode from corrosion to aqueous or other ion-containing inks. The invention is of particular benefit in piezoelectric printheads.

Abstract: Methods and apparatus for laser marking individual objects with indicia at a marking station wherein a predetermined window exists during which each object can be marked as the objects are conveyed along at least one path at a predetermined speed. In some embodiments, at least first and second lasers positioned adjacent one or more paths are configured to direct a laser beam onto the objects to mark the same with indicia as the objects pass through the marking station, with each of the first and second lasers marking alternate following objects as they pass through the marking station.

Abstract: Methods and compositions for the diagnosis of cancer susceptibilities, defective DNA repair mechanisms and treatments thereof are provided. Among sequences provided here, the FANCD2 gene has been identified, and probes and primers are provided for screening patients in genetic-based tests and for diagnosing Fanconi Anemia and cancer. The FANCD2 gene can be targeted in vivo for preparing experimental mouse models for use in screening new therapeutic agents for treating conditions involving defective DNA repair. The FANCD2 polypeptide has been sequenced and has been shown to exist in two isoforms identified as FANCD2-S and the monoubiquinated FANCD-L form. Antibodies including polyclonal and monoclonal antibodies have been prepared that distinguish the two isoforms and have been used in diagnostic tests to determine whether a subject has an intact Fanconi Anemia/BRCA pathway.

Abstract: The present invention relates to molecules and molecular complexes which comprise the active site binding pockets of JNK3 or close structural homologues of the active site binding pockets.

Abstract: A device for separating and purifying useful quantities of particles comprises: (a) an anolyte reservoir connected to an anode, the anolyte reservoir containing an electrophoresis buffer; (b) a catholyte reservoir connected to a cathode, the catholyte reservoir also containing the electrophoresis buffer; (c) a power supply connected to the anode and to the cathode; (d) a column having a first end inserted into the anolyte reservoir, a second end inserted into the catholyte reservoir, and containing a separation medium; (e) a light source; (f) a first optical fiber having a first fiber end inserted into the separation medium, and having a second fiber end connected to the light source; (g) a photo detector; (h) a second optical fiber having a third fiber end inserted into the separation medium, and having a fourth fiber end connected to the photo detector; and (i) an ion-exchange membrane in the anolyte reservoir.

Abstract: A device for separating and purifying useful quantities of particles comprises: a. an anolyte reservoir connected to an anode, the anolyte reservoir containing an electrophoresis buffer; b. a catholyte reservoir connected to a cathode, the catholyte reservoir also containing the electrophoresis buffer; c. a power supply connected to the anode and to the cathode; d. a column having a first end inserted into the anolyte reservoir, a second end inserted into the catholyte reservoir, and containing a separation medium; e. a light source; f. a first optical fiber having a first fiber end inserted into the separation medium, and having a second fiber end connected to the light source; g. a photo detector; h. a second optical fiber having a third fiber end inserted into the separation medium, and having a fourth fiber end connected to the photo detector; and i. an ion-exchange membrane in the anolyte reservoir.

Abstract: A method for electroless plating of metal on a laser-patterned substrate. A substrate is provided on which both a thermal imaging layer and catalytic layer are deposited. On exposure to a laser beam, sufficient levels of radiation are converted to heat in the thermal imaging layer to render the exposed regions of the adjacent catalytic layer inactive. The laser-patterned substrate is then exposed to a reaction solution which initiates the growth of a metal film on the unexposed regions of the catalytic layer.

Abstract: A surfactant selected from an acrylate-modified polydimethylsiloxane or a polyether-modified polydimethylsiloxane is used, together with at least a colorant and a UV-curable organic diluent, in a non-aqueous UV-curable ink composition suitable for ink jet printing. The use of this type of surfactant prevents the ink composition from causing the loss of more than 5% of the nozzles in an ink jet print head and enables the composition to provide a hole to area ratio of no more than 0.05. The present ink compositions have particular application in the printing of packaging for foodstuffs.

Abstract: A system and method enhancing source code management with existing virus detection methods in a library management system to detect potentially malicious code. Malicious code that is introduced into a software product may be detected before the code is able to damage stored data and other software by preventing a product build with the malicious code. Source code received at a code management library system from a set of software developers in a collaborative development environment is moved into a staging area. A determination is made in the staging area as to whether malicious code exists in the source code. If malicious code exists, the library management system does not forward the source code to the software product build and notifies a system administrator of the presence of the malicious code.

Abstract: The present invention is a hollow body stringed musical instrument that utilizes a low mass, soundboard having a 12 to 25 foot radius dome configuration. The soundboard is made of a three ply torsion box design utilizing a honeycomb stiffening layer as the central core. Linear adjustable tuning braces are incorporated in the hollow body. The side and back of the instrument are also of a three ply construction having a polymer ir inorganic foam as the central layer. (Preferably this will be a closed cell foam.) The back also has a domed configuration with a 12 to 15 foot radius. All structural braces are eliminated from the interior of the instrument's body.

Abstract: A device for separating and purifying useful quantities of particles comprises: a. an anolyte reservoir connected to an anode, the anolyte reservoir containing an electrophoresis buffer; b. a catholyte reservoir connected to a cathode, the catholyte reservoir also containing the electrophoresis buffer; c. a power supply connected to the anode and to the cathode; d. a column having a first end inserted into the anolyte reservoir, a second end inserted into the catholyte reservoir, and containing a separation medium; e. a light source; f. a first optical fiber having a first fiber end inserted into the separation medium, and having a second fiber end connected to the light source; g. a photo detector; h. a second optical fiber having a third fiber end inserted into the separation medium, and having a fourth fiber end connected to the photo detector; and i. an ion-exchange membrane in the anolyte reservoir.

Abstract: A repair mechanism within a code management library system for repairing build code that is infected with malicious code. When a virus pattern is detected in a component of a source code, other components in the source code containing dependencies upon the first component are identified. This identification may be based on rules defined from relationships between the infected component and the other components in the source code. The component and the other components that are identified as having dependencies upon the infected component are retracted from the software product build. The infected component and the other identified components are then replaced with a previous archive of the code build. The software product build of the source code may then be performed.

Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of JNK3. A computer comprising such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to JNK3 or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of JNK3 or close structural homologues of the active site binding pockets.

Abstract: A method for electroless plating of metal on a laser-patterned substrate. A substrate is provided on which both a thermal imaging layer and catalytic layer are deposited. On exposure to a laser beam, sufficient levels of radiation are converted to heat in the thermal imaging layer to render the exposed regions of the adjacent catalytic layer inactive. The laser-patterned substrate is then exposed to a reaction solution which initiates the growth of a metal film on the unexposed regions of the catalytic layer.

Abstract: Embodiments of the present invention comprise an apparatus for laser marking individual objects with indicia at a marking station wherein a predetermined window exists during which each object can be marked as the objects are conveyed along at least one path at a predetermined speed, the apparatus comprising, at least first and second lasers positioned adjacent one or more paths configured to direct a laser beam onto the objects to mark the same with indicia as the objects pass through the marking station, with each of the first and second lasers marking alternate following objects as they pass through the marking station.

Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site-binding pockets of JNK3. A computer comprising such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to JNK3 or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of JNK3 or close structural homologues of the active site binding pockets.

Abstract: A method and system for ranking objects based on relationships with objects of a different object type is provided. The ranking system defines an equation for each attribute of each type of object. The equations define the attribute values and are based on relationships between the attribute and the attributes associated with the same type of object and different types of objects. The ranking system iteratively calculates the attribute values for the objects using the equations until the attribute values converge on a solution. The ranking system then ranks objects based on attribute values.