Abstract: A search system associates contextual metadata with search terms and/or stored terms to facilitate identification of relevant information. In one implementation, a search term is identified (4304) from a received search request. The search term is then rewritten (4306) in standard form and the standard form term is then set (4308) as the current search parameter. A source database is then searched (4310) using the current search parameter. If any results are obtained (4312) these results may be output (4320) to the user. If no results are obtained, a parent classification of the search term is set (4316) as the current search parameter and the process is repeated. The invention thereby provides the ease of use of term searching with the comprehensiveness of category searching.

Abstract: A machine based tool and associated logic and methodology are used in converting data from an input form to a target form using context dependent conversion rules, and in efficiency generating an index that may be utilized to access the converted data in a database. Once the data has been converted, an index data structure for each data object may be automatically generated that encodes one or more characteristics or attributes of the converted data so that an entity may access the data using the index structure. As an example, the one or more characteristics may include categories, subcategories, or other attributes of the data.

Abstract: The present invention provides a flow apparatus (10) having a flow control valve (12) having a housing (14), an aperture (16), an aperture obturator (18) and an actuator (20) for moving said obturator (16) between a first closed position and multiple open positions (B-L), characterised by a valve position monitor (21) for monitoring the position of the valve (12) and comprising a plurality of discrete sensors (28a to 28e) associated with a plurality of open positions (B-L) of said valve for monitoring the presence or absence of one or more members (26) movable with said valve (12). The arrangement may be used to monitor the valve position and such monitoring may be of use in the prediction of the amount of fluid remaining within a cylinder (32) to which it has been attached.

Abstract: A string analysis tool for calculating a similarity metric between a source string and a plurality of target strings. The string analysis tool may include optimizations that may reduce the number of calculations to be carried out when calculating the similarity metric for large volumes of data. In this regard, the string analysis tool may represent strings as features. As such, analysis may be performed relative to features (e.g., of either the source string or plurality of target strings) such that features from the strings may be eliminated from consideration when identifying target strings for which a similarity metric is to be calculated. The elimination of features may be based on a minimum similarity metric threshold, wherein features that are incapable of contributing to a similarity metric above the minimum similarity metric threshold are eliminated from consideration.

Abstract: Computer-based tools and methods for conversion of data from a first form to a second form without reference to the context of data to be converted. The conversion may be facilitated by matching source data with external information (e.g., public and/or private schema) that contain rules (e.g., context specific rules) for conversion of the data. The matching may be performed based on an optimized index string matching technique that may be operable to match source data to external information that is context dependent without specific identification of the context of either the source data or the external information identified. Accordingly, the conversion of data may be performed in an unsupervised machine learning environment.

Abstract: The present invention provides novel selective androgen receptor modulators and their salts and pharmaceutical compositions thereof.

Abstract: A medical device is described having a handle and an end effector coupled to the handle. The end effector has at least one electrode for providing electrical signals to a tissue or vessel to be treated. An RF drive circuit is provided for generating an RF drive signal that is applied to the end effector electrode. The RF drive circuit includes a resonant circuit and a frequency controller is used to vary the frequency of a signal passed through the resonant circuit in order to control the power supplied to the end effector electrode.

Abstract: This invention relates to methods for removing chewing gum and residues thereof from substrates using chewing gum modifying compositions comprising ionic liquids. In one embodiment, the chewing gum modifying composition may be used together with one or more oxidising reagents. In another embodiment, the chewing gum removal compositions further comprise one or more enzymes and one or more enzyme mediator compounds. The invention further relates to novel ionic liquid and enzyme compositions that are suitable for use in removing chewing gum residues.

Abstract: A search system associates contextual metadata with search terms and/or stored terms to facilitate identification of relevant information. In one implementation, a search term is identified (4304) from a received search request. The search term is then rewritten (4306) in standard form and the standard form term is then set (4308) as the current search parameter. A source database is then searched (4310) using the current search parameter. If any results are obtained (4312) these results may be output (4320) to the user. If no results are obtained, a parent classification of the search term is set (4316) as the current search parameter and the process is repeated. The invention thereby provides the ease of use of term searching with the comprehensiveness of category searching.

Abstract: A machine based tool and associated logic and methodology arc used in converting data from an input form to a target form using context dependent conversion rules. A frame-slot architecture is utilized where a frame represents an intersection between a contextual cue recognized by the machine tool, associated content and related constraint information to specific to that conversion environment. A slot represents an included chunk of information. An exemplary conversion system (400) includes a parser (402) for use in parsing and converting an input stream (403) to provide an output stream (411) in a form for use by a target system (412). The parser (402) uses information from a public schema (406), a private schema (408) and a grammar (410). The public schema (406), private schema (408) and grammar (410) may include conversion rules applicable to less than the whole of a subject matter area including the input stream (403).

Abstract: This invention relates to ethanol production as a product of bacterial fermentation.

Abstract: A machine based tool and associated logic and methodology are used in converting data from an input form to a target form using context dependent conversion rules. In particular, a frame-slot architecture is utilized where a frame represents an intersection between a contextual cue recognized by the machine tool, associated content and related constraint information to specific to that conversion environment, whereas a slot represents an included chunk of information. An exemplary conversion system (400) includes a parser (402) for use in parsing and converting an input stream (403) from a source (404) to provide an output stream (411) in a form for use by a target system (412). To accomplish the desired conversion, the parser (402) uses information from a public schema (406), a private schema (408) and a grammar (410). The public schema (406), private schema (408) and grammar (410) may include conversion rules applicable to less than the whole of a subject matter area including the input stream (403).

Abstract: The present invention relates to the production of ethanol as a product of bacterial fermentation. In particular this invention relates to a novel method of gene inactivation and gene expression based upon homologous recombination. The method is particularly useful in connection with species of Bacillus such as B. stereothermophilus, B. calvodelox, B. caldotenax, B. thermoglucosidasius, B. coagulans, B. licheniformis, B. thermodenitrificans, and B. caldolyticus.

Abstract: This invention relates to methods for removing chewing gum and residues thereof from substrates using chewing gum modifying compositions comprising ionic liquids. In one embodiment, the chewing gum modifying composition may be used together with one or more oxidising reagents. In another embodiment, the chewing gum removal compositions further comprise one or more enzymes and one or more enzyme mediator compounds. The invention further relates to novel ionic liquid and enzyme compositions that are suitable for use in removing chewing gum residues.

Abstract: The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly reduced bones mass, osteoporosis, osteopenia, or reduced muscle mass or strength, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof. X-17142.

Abstract: The invention relates to a process for producing organic acids, acid derivatives thereof and/or organic alcohols. In particular, the invention relates to a process for culturing a butyric acid-producing micro-organism in a culture vessel; transferring a portion of the butyric acid which is produced in the culture vessel to a separate compartment; and then reintroducing a portion of the acids from the second compartment in a controlled manner into the culture vessel. The invention also relates to a process for making butanol. The invention further relates to a process for culturing a butyrate-producing micro-organism in a first compartment of an electrochemical reactor, passing a direct current electric field across the electrochemical reactor and harvesting butyric acid or acid derivatives thereof in a second compartment of the reactor. The invention further relates to a process for producing butanol from the butyric acid.

Abstract: The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of formula (I).

Abstract: The present invention relates to methods for making recombinant thermophilic bacteria of the family Bacillaceae. In particular, recombinant thermophilic Bacillaceae are provided which have been engineered to produce butanol and/or butyrate. Preferably, heterologous nucleic acid molecules encoding one or more butanol or butyrate biosynthetic pathway enzymes are introduced into a thermophilic Bacillaceae in order to produce a recombinant thermophilic Bacillaceae which is capable of producing butanol. The Bacillaceae is preferably of the genus Geobacillus or Ureibacillus. The invention also relates to a method of producing butanol using the Bacillaceae of the invention.

Abstract: In connection with a machine-based system for transforming data from a source form to a target form, a tool is provided for sharing information established in developing a transformation model. The shared information may relate to rules for mapping source collection terms to standardized terms, rules for ordering or syntax, rules for classifying terms or other transformation rules. Such information defines a knowledge base for the project. The knowledge base is divided into domains and subdomains that define a hierarchy that includes dependencies and references. These dependencies and references are used for domain management such that any conflicts and inconsistencies can be identified and arbitrated. In this manner, information sharing is accommodated, for example, for efficient knowledge base creation and multi-user functionality.

Abstract: This invention relates to ethanol production as a product of bacterial fermentation.