Abstract: Methods and apparatus in a partitionable computing system. A first link controller is associated with a first partition. A second link controller is associated with a second partition. A computing element communicated with link controllers to establish or deny communication between the partitions.

Abstract: Compounds of formula I: inhibit gamma-secretase and hence find use in treatment or prevention of Alzheimer's disease.

Abstract: Distributing communications between paths, comprises providing a plurality of destinations, providing a plurality of communications paths such that each of the plurality of destinations can be accessed over each of the plurality of communications paths, defining destination addresses interleaved over the plurality of destinations, sending communications from a source to a plurality of the interleaved addresses, and selecting different ones of the plurality of paths for successive communications that are sent to addresses on different destinations, wherein the path for a communication is selected using at least a part of the address of the communication.

Abstract: The present invention relates to compounds of formula (Ia) wherein A, B, n, m, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are defined herein, and pharmaceutically acceptable salts thereof; the compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Abstract: Methods and apparatus in a partitionable computing system. The system can include a computer readable medium comprising instructions configured to move an element of a first partition to a second partition.

Abstract: A resonator for a vehicle air intake system is disclosed, wherein the resonator is variable tuned to militate against the emission of sound waves caused by the engine and other sources at a wide range of engine speeds.

Abstract: A system and methods for handling financial document returns and processing exceptions are disclosed. Embodiments of the invention provide a returns and exceptions platform to image enable check returns and exceptions within a financial institution. This capability can be in part enabled by a system that provides both for decisioning based on images, and dispatching or exporting images and data in a plurality of formats from the system into which they are first loaded, so that paper items need not be referenced again. The plurality of formats for export can include X9.37i files, external and internal cash letters, and image replacement documents. The image-based processes of the invention can be implemented by a plurality of application servers and a plurality of database servers interconnected by a network.

Abstract: Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.

Abstract: A multi-processor system architecture comprises: a cabinet; a plurality of processor cell modules disposed within the cabinet; a plurality of link router modules disposed within the cabinet; and a plurality of cables connecting the plurality of processor cell modules through the plurality of link router modules.

Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.

Abstract: Methods and apparatus in a partitionable computing system. A processor communicates with a packet former. The packet former can be configured to construct a data packet that can include security status information related to a partition or processor.

Abstract: A novel process for preparing cyclohexanone derivatives of formula (I) is described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.

Abstract: The present invention relates compounds of the formula (I); wherein R1, R2, R3, R4, R5, R6, R7, R8, and R10 represent a variety of substituents; A represents NR9 or O; B represents a bond, CH2, NR9 or O, wherein one or both hydrogen atoms in said CH2 moiety may be replaced with one or both of R7 and R8, or alternatively, one of the hydrogen atoms in said CH2 moiety together with a hydrogen atom from an adjacent carbon are replaced by a double bond; with the proviso that when A is O, then B is NR9; n is zero, 1 or 2; and pharmaceutically acceptable salts thereof.

Abstract: A valve assembly comprising a valve body, a first movable pressure responsive element, and a second pressure responsive movable element, wherein the valve assembly further comprises a resilient biasing element and a movable third pressure responsive element, the resilient biasing element extending between the third pressure responsive element and the valve body and the third pressure responsive element being adapted to act on both the first and second pressure responsive elements to transmit the biasing force of the resilient biasing element to both the first and second pressure responsive elements.

Abstract: The present invention relates compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 represent a variety of substituents, ring A is a phenyl or pyridyl ring; d is zero, 1 or 2; and pharmaceutically acceptable salts and N-oxides thereof.

Abstract: A partitionable computer system and method of operating the same is disclosed. The partitionable computer system has a state machine, a processor, and a device controller. The state machine can be configured to monitor the status of a partition of the partitionable computer system. The information provided by the state machine can be used to provide security within the partitionable computing system.

Abstract: The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Abstract: Compounds of formula I: wherein Ar1 and Ar2 are optionally substituted aryl or heteroaryl, L is a bond, ?CH— or —(CHRa)n—, and X is SCN, SR1, S(O)R1, (CRaRb)mSO2R1, SO2N(R2)2, SO2NHCOR1, SO2NHN(R2)2, OSO2N(R2)2, OS(O)N(R2)2, OSO2NHCOR1, COR4, NHCOR1, NHCO2R1, NHCON(R2)2, NHSO2R1 or NHSO2N(R2)2, inhibit the processing of APP by gamma secretase, and hence are useful in treatment of Alzheimer's disease.

Abstract: A valve assembly comprising a chamber, the chamber having an inlet which is adapted to be connected to a source of relatively high pressure fluid, and an outlet which is adapted to be connected to a source of relatively low pressure fluid, and a switch valve which is switchable between a first configuration in which the valve closes the outlet and opens the inlet, and a second configuration in which the valve closes the inlet and opens the outlet, characterised in that a flow control device is provided between the outlet and the volume of relatively low pressure fluid, the flow control device including a restrictor portion which restricts flow of fluid through the flow control device, the extent to which fluid flow is restricted decreasing as the fluid pressure in the chamber increases.

Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.