Abstract: A conveyor system comprising a synchronization unit having a first conveyor belt, a second conveyor belt disposed adjacent to the first conveyor belt, an inlet end and an outlet end. The system further comprises a joint shuttle disposed between the first conveyor belt and the second conveyor belt, each of the first and second conveyor belts having a variable length while the distance between the inlet end and the outlet end is fixed. A discharge conveyor belt is disposed upstream the inlet end and is operating at a first velocity (VD). At a time T1, the velocity of the first conveyor belt (V1T1) is equal to the velocity of the discharge conveyor belt (VD) and, at a time T2, the velocity of the first conveyor belt (V1T2) is equal to the velocity of the second conveyor belt (Vm), without relative movement between the conveyor belts and objects conveyed thereon.

Abstract: The invention describes peptide ligands specific for human plasma Kallikrein.

Abstract: The invention provides a method for conjugating a peptide displayed on a genetic display system to a molecular scaffold performed on an ion exchange resin.

Abstract: The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4, R3 is C1-6-alkyl which is substituted by R5 and R6, R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl, R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond and wherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen, and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well a

Abstract: The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4, R3 is C1-6-alkyl which is substituted by R5 and R6, R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl, R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond and wherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen, and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pha

Abstract: A gum massaging mouthpiece includes a main body having a generally C-shaped base member that is in communication with an integrally formed inner and outer wall. A plurality of nubs are disposed along the mouthpiece so as to make contact with the gums of a user, and a plurality of electrically controlled vibrating elements provide a vibration force to the nubs for massaging the gums of a user.

Abstract: The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4, R3 is C1-6-alkyl which is substituted by R5 and R6, R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl, R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond and wherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen, and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as wel

Abstract: Process for producing a ceramic composite structure includes impregnating a reinforcing material with a suitable precursor slurry composition including thermosetting resin, a suitable curing agent, a ceramic component, a carbonaceous solids component, and optionally, a suitable solvent. Exemplary thermosetting resins include polyesters, vinyl esters, epoxy resins, bismaleimide resins, and polyimide resins. The carbonaceous solids component provides a suitable amount of carbon char upon pyrolization. The preform may be dried prior to curing to remove solvents and thereby provide a working material comprising up to 70 volume % solids. The preform is cured, pyrolized, and infiltrated with molten silicon to form a composite article. The thermosetting resin is selected for processibility, green strength, and relatively fast cure cycle.

Abstract: A conveyor system comprising a synchronization unit having a first conveyor belt, a second conveyor belt disposed adjacent to the first conveyor belt, an inlet end and an outlet end. The system further comprises a joint shuttle disposed between the first conveyor belt and the second conveyor belt, each of the first and second conveyor belts having a variable length while the distance between the inlet end and the outlet end is fixed. A discharge conveyor belt is disposed upstream the inlet end and is operating at a first velocity (VD). At a time T1, the velocity of the first conveyor belt (V1T1) is equal to the velocity of the discharge conveyor belt (VD) and, at a time T2, the velocity of the first conveyor belt (V1T2) is equal to the velocity of the second conveyor belt (Vm), without relative movement between the conveyor belts and objects conveyed thereon.

Abstract: The present invention describes a receptacle (10) for a personal care composition comprising a container (12), a separate closure member (14), at least one applicator means (22) for the application of the composition to a user and at least one removal means (24) for the removal of the composition from a user, wherein: the container comprises a reservoir means for retaining a quantity of composition and an aperture (18) in an upper portion of said container; and wherein the closure member has a hollow construction and a releasably sealable lid member (16), and the interior of the closure member is configured to house the at least one applicator means and the at least one removal means; and wherein securing means (20) are provided to permit the closure member to be releasably engagable with the container to close the aperture when engaged. The present invention also describes a method of applying a personal care composition.

Abstract: The invention provides a method for conjugating a peptide displayed on a genetic display system to a molecular scaffold performed on an ion exchange resin.

Abstract: The invention describes peptide ligands specific for human plasma Kallikrein.

Abstract: The invention describes a method for selecting a polypeptide ligand having a desired level of specificity for a target, wherein the polypeptide ligand comprises a polypeptide comprising at least three reactive groups, separated by at least two loop sequences, and a molecular scaffold which forms covalent bonds with the reactive groups of the polypeptide such that at least two polypeptide loops are formed on the molecular scaffold, comprising (i) screening at least two different sets of polypeptide ligands against the target, and selecting one or more ligands from each library which interact with the target; (ii) comparing the activity of the selected ligands with one or more paralogues or orthologues of the target; and (iii) further selecting one or more ligands according to their activity towards said one or more paralogues or orthologues; wherein said two or more different sets of ligands differ in the length of the polypeptide loops formed on the molecular scaffold.

Abstract: A system and method are disclosed for providing a mobile persona environment hosted by a network accessible server that can be activated by network connected client device. The client device points the portion of its file system used by the operating system to configure the desktop environment to a persona container hosted by the server. The persona container includes user data, applications and operating system settings or policies that are used to configure the operating system of the client device to provide the mobile persona environment. The client device obtains user profile information and connection information from a persona reference object stored on the client device. Applications are executed locally on the client device while the data remains secure in the network accessible server.

Abstract: A theft deterrent enclosure that eliminates unauthorized access is disclosed. The enclosure includes a front and back cover. A key lock cylinder is mounted in a lock opening of the front cover such that it blocks the lock opening in a locked position. A keyed interface operates a clamp mounted on a threaded shaft such that the clamp secures the front and hack covers in a closed position. The keyed interface is positioned on an interior side of the enclosure that is opposite and aligned with the lock opening. The theft deterrent enclosure can only he opened from a locked position by engaging the key lock cylinder with a key, removing the key lock cylinder tumbler, inserting the security keyed tool adapted to engage the keyed interface through the lock opening and disengaging the mounting clamp.

Abstract: A theft deterrent enclosure that eliminates unauthorized access is disclosed. The enclosure includes a door assembly having three sides and a wrapper assembly having three sides that mate to form a lockable enclosure. A key lock cylinder is mounted in a lock opening of the door assembly such that it blocks the lock opening in a locked position. A keyed interface operates a fastener, such as a compression latch, threaded coupling or lock plate, which is mounted on the door assembly such that the fastener secures the door assembly and the wrapper assembly in a closed position. The keyed interface is positioned on an interior side of the enclosure that is opposite and aligned with the lock opening. A guide sleeve is positioned inside the enclosure that guides a security keyed tool inserted through the lock opening toward the keyed interface.

Abstract: A hand-held dispensing device having a dispenser incorporating: (i) a dispenser body defining a dispensing chamber for holding a substance; (ii) an outlet communicating with the dispensing chamber; (iii) a dispensing mechanism for dispensing the substance through the outlet; and (iv) an actuating member resiliently mounted for movement relative to the dispenser body to actuate the dispensing mechanism. The dispenser is operably connected to and manually slidable relative to a handle between a non-use position, and an operative position. The device further comprises a locking assembly for releasably locking the dispenser body to the handle in the operative position to prevent said manual sliding movement of the dispenser body, whereby a user may grasp the handle and effect manual movement of the actuating member relative to the handle and the dispenser body, against the action of the biasing member, to actuate the dispensing mechanism and dispense the contents of the dispensing chamber.