Patents by Inventor Ehud Gazit

Ehud Gazit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide nanostructures and methods of generating and using the same
    Patent number: 8350004
    Abstract: A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: January 8, 2013
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Meital Reches, Ehud Gazit
  • Peptide nanostructures encapsulating a foreign material and method of manufacturing same
    Patent number: 8314069
    Abstract: A composition comprising a material at least partially enclosed by a tubular, spherical or planar nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: November 20, 2012
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud Gazit, Meital Reches
  • PHOTOCATALYTIC HYDROGEN PRODUCTION IN CYANOBACTERIA
    Publication number: 20120115202
    Abstract: A cyanobacterial cell comprising a PSI complex which accepts electrons from at least one respiratory cytochrome is disclosed. Methods of generating same and use of same for the production of hydrogen gas are also disclosed.
    Type: Application
    Filed: May 26, 2010
    Publication date: May 10, 2012
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Nathan Nelson, Iftach Yacoby, Ehud Gazit, Itai Benhar
  • PEPTIDE NANOSTRUCTURES AND METHODS OF GENERATING AND USING THE SAME
    Publication number: 20120063276
    Abstract: A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 15, 2012
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Meital Reches, Ehud Gazit
  • FORMATION OF ORGANIC NANOSTRUCTURE ARRAY
    Publication number: 20120021954
    Abstract: A nanostructure array is disclosed. The nanostructure array comprises a plurality of elongated organic nanostructures arranged generally perpendicularly to a plane.
    Type: Application
    Filed: December 4, 2007
    Publication date: January 26, 2012
    Inventors: Ehud Gazit, Meital Reches
  • COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20110319334
    Abstract: Isolated peptides are provided, being less than 20 amino acids in length. The peptides comprising an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimetics and/or fragment thereof, the peptides being capable of inhibiting alpha synuclein aggregation. Pharmaceutical compositions comprising same are also provided as well as uses thereof.
    Type: Application
    Filed: March 9, 2010
    Publication date: December 29, 2011
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ronit Shaltiel-Karyo, Ehud Gazit
  • Peptide nanostructures and methods of generating and using the same
    Patent number: 8053554
    Abstract: A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: November 8, 2011
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Meital Reches, Ehud Gazit
  • PEPTIDE NANOSTRUCTURES ENCAPSULATING A FOREIGN MATERIAL AND METHOD OF MANUFACTURING SAME
    Publication number: 20110266517
    Abstract: A composition comprising a material at least partially enclosed by a tubular, spherical or planar nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Application
    Filed: July 11, 2011
    Publication date: November 3, 2011
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud GAZIT, Meital Reches
  • NAPHTHOQUINONE DERIVATIVES USEFUL FOR PREVENTION OF AMYLOID DEPOSITS AND TREATMENT OF DISEASES INVOLVING AMYLOIDOGENESIS
    Publication number: 20110224184
    Abstract: The present invention provides pharmaceutical compositions comprising substituted 1,4 naphthoquinones that are effective in preventing oligomerization of beta amyloid and subsequent pathologies associated with amyloid fibrils. These compositions are useful for the treatment of disease involving amyloidogenesis including neurodegenerative diseases such as Alzheimer's Disease or senile dementia. Particularly effective compositions comprise 1,4 naphthoquinones substituted with an amino acid residue selected from a heterocyclic or aromatic amino acid.
    Type: Application
    Filed: September 6, 2009
    Publication date: September 15, 2011
    Applicant: RAMOT AT TEL AVIV UNIVERSITY LTD.
    Inventors: Roni Scherzer, Ehud Gazit, Daniel Segal
  • Peptide nanostructures encapsulating a foreign material and method of manufacturing same
    Patent number: 8017586
    Abstract: A composition comprising a material at least partially enclosed by a tubular, spherical or planar nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: September 13, 2011
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud Gazit, Meital Reches
  • Peptides directed for diagnosis and treatment of amyloid-associated diseases
    Patent number: 8012929
    Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: September 6, 2011
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud Gazit
  • USE OF A CINNAMON BARK EXTRACT FOR TREATING AMYLOID-ASSOCIATED DISEASES
    Publication number: 20110200692
    Abstract: The present application disclosed the use of a cinnamon extract in the treatment of amyloid-associated diseases and disorders, such as Alzheimer's disease.
    Type: Application
    Filed: October 11, 2009
    Publication date: August 18, 2011
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Michael Ovadia, Ehud Gazit, Anat Frydman-Marom
  • METHOD AND SYSTEM FOR EMITTING LIGHT
    Publication number: 20110174064
    Abstract: A method of predicting formation of an amyloid plaque in a peptide sample is disclosed. The method comprises determining presence of quantum confinement in the sample, and predicting that formation of an amyloid plaque is likely to occur if the sample exhibits quantum confinement.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 21, 2011
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Nadav Amdursky, Nadav Amdursky, Ehud Gazit, Gil Rosenman
  • METHOD AND SYSTEM FOR MANIPULATING ORGANIC NANOSTRUCTURES
    Publication number: 20110156109
    Abstract: A method of manipulating an organic nanostructure is disclosed. The method comprises: contacting a liquid sample having the organic nanostructure therein with an arrangement of electrodes, and applying voltage to the arrangement of electrodes to manipulate and immobilize the organic nanostructure over the electrodes by electrokinetics.
    Type: Application
    Filed: December 28, 2010
    Publication date: June 30, 2011
    Applicants: Ramot at Tel-Aviv University Ltd., Technical University of Denmark (DTU), The University of Crete
    Inventors: Ehud GAZIT, Lihi Adler-Abramovich, Jaime Alberto Castillo Leon, Maria Ioannou Dimaki, Winnie Edith Svendsen, Emmanouil Kasotakis, Anna Mitraki
  • Peptide nanostructure-coated electrodes
    Patent number: 7879212
    Abstract: An electrode coated with peptide nanostructures, composed of self-assembled peptides, is disclosed. The electrode is capable of conducting a response current resulting from an electrochemical reaction. The electrode can form a part of an electrochemical cell, a detector and a sensor array. Methods utilizing an electrochemical cell, a detector or a sensor array comprising the electrode for detecting an Analyte in a sample and kits containing same are also disclosed.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: February 1, 2011
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Miri Yemini, Meital Reches, Judith Rishpon, Ehud Gazit
  • PEPTIDE NANOSTRUCTURES CONTAINING END-CAPPING MODIFIED PEPTIDES AND METHODS OF GENERATING AND USING THE SAME
    Publication number: 20100291828
    Abstract: A nanostructure composed of a plurality of peptides, each peptide containing at least one aromatic amino acid, whereby one or more of these peptides is end-capping modified, is disclosed. The nanostructure can take a tubular, fibrillar, planar or spherical shape, and can encapsulate, entrap or be coated by other materials. Methods of preparing the nanostructure, and devices and methods utilizing same are also disclosed.
    Type: Application
    Filed: July 26, 2010
    Publication date: November 18, 2010
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Meital RECHES, Ehud Gazit
  • COMPOSITIONS FOR TREATING AMYLOID ASSOCIATED DISEASES
    Publication number: 20100240726
    Abstract: Indole derivatives, compositions including same, and methods utilizing same for the treatment of amyloid associated diseases, such as type II diabetes mellitus, Alzheimer's dementia or diseases, systemic and localized amyloidosis, and prion-related encephalopathies are provided.
    Type: Application
    Filed: June 6, 2010
    Publication date: September 23, 2010
    Applicant: Tel Aviv University Future Technology Development L.P.
    Inventors: Ehud GAZIT, Tomer Cohen
  • Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
    Patent number: 7786086
    Abstract: A nanostructure composed of a plurality of peptides, each peptide containing at least one aromatic amino acid, whereby one or more of these peptides is end-capping modified, is disclosed. The nanostructure can take a tubular, fibrillar, planar or spherical shape, and can encapsulate, entrap or be coated by other materials. Methods of preparing the nanostructure, and devices and methods utilizing same are also disclosed.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: August 31, 2010
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Meital Reches, Ehud Gazit
  • Peptides directed for diagnosis and treatment of amyloid-associated disease
    Patent number: 7781396
    Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: August 24, 2010
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud Gazit
  • VAPOR DEPOSITION OF BIOMOLECULES
    Publication number: 20100204443
    Abstract: A coating method is disclosed. The coating method comprises placing a substrate and a biomolecule in a chamber and applying a vapor deposition process within the chamber so as to form a solid deposition of the biomolecule on at least a portion of a surface of the substrate.
    Type: Application
    Filed: August 13, 2008
    Publication date: August 12, 2010
    Applicant: Ramont At Tel Aviv University Ltd.
    Inventors: Ehud Gazit, Lihi Adler-Abramovich, Daniel Aronov, Gil Rosenman