Patents by Inventor Elizabeth Jane Lawlor

Elizabeth Jane Lawlor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 6303124
    Abstract: The invention provides lysS polypeptides and DNA (RNA) encoding lysS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 13, 2000
    Date of Patent: October 16, 2001
    Assignee: SmithKline Beecham Corporation
    Inventor: Elizabeth Jane Lawlor
  • Compounds
    Patent number: 6294175
    Abstract: The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: September 25, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Compounds
    Patent number: 6284489
    Abstract: The invention provides tyrS polypeptides and DNA (RNA) encoding tyrS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tyrS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: September 4, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Elizabeth Jane Lawlor, John Edward Hodgson
  • Compounds
    Patent number: 6270999
    Abstract: The invention provides lysS polypeptides and DNA (RNA) encoding lysS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: August 7, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • RatC
    Patent number: 6248557
    Abstract: The invention provides ratC polypeptides and DNA (RNA) encoding ratC polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratC polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 21, 1998
    Date of Patent: June 19, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • Polynucleotides encoding glutamyltrna synthetase from staphylococcus aureus
    Patent number: 6238900
    Abstract: The invention provides glutamyl tRNA from Staphylococcus aureus synthetase polypeptides and DNA (RNA) encoding glutamyl tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glutamyl tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: May 29, 2001
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Arginyl tRNA synthetase polynucleotides
    Patent number: 6232097
    Abstract: The invention provides argS polypeptides and DNA (RNA) encoding argS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing argS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: May 15, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Glutamyl-tRNA synthetase from Staphylococcus aureus
    Patent number: 6218159
    Abstract: The invention provides glutamyl-tRNA synthetase polypeptides and DNA (RNA) encoding glutamyl-tRNA synthetase polypeptides from Staphylococcus aureus. The invention also provides methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides for protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: April 17, 2001
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Compounds
    Patent number: 6210940
    Abstract: The invention provides aspS polypeptides and DNA (RNA) encoding aspS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aspS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: April 3, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Compounds
    Patent number: 6200774
    Abstract: The invention provides ratB polypeptides and DNA (RNA) encoding ratB polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratB polypeptides to screen for antibacteria, compounds.
    Type: Grant
    Filed: January 21, 1998
    Date of Patent: March 13, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • Phenylalanyl tRNA synthetase polypeptides from streptococcus pneumoniae
    Patent number: 6200787
    Abstract: The invention provides phenylalanyl tRNA synthetase (pheS) (beta) and pheS (alpha) polypeptides and DNA (RNA) encoding pheS (beta) and pheS (alpha) polypetides from Streptoccus pneumoniae and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pheS (beta) and pheS (alpha) polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: March 13, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Tryptophanyl tRNA synthetase polypeptides of streptococcus
    Patent number: 6165759
    Abstract: The invention provides Tryptophanyl tRNA Synthetase polypeptides and DNA (RNA) encoding Tryptophanyl tRNA Synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Tryptophanyl tRNA Synthetase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: December 26, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Phenylalanyl tRNA synthetase from streptococcus pneumoniae
    Patent number: 6162625
    Abstract: The invention provides phenylalanyl tRNA synthelase, pheS, (alpha) polypeptides and DNA (RNA) encoding pheS (alpha) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pheS (alpha) polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: December 19, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Deborah Dee Jaworski, Elizabeth Jane Lawlor, Min Wang
  • RNA-dependent amidotransferase from Staphylococcus aureus
    Patent number: 6150340
    Abstract: The invention provides ratA polypeptides and DNA (RNA) encoding ratA polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: November 21, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • Amidotransferase, ratB, of streptococcus pneumoniae
    Patent number: 6136560
    Abstract: The invention provides ratB polypeptides and DNA (RNA) encoding ratB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: October 24, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • DNA encoding streptococcus pneumoniae trigger factor polypeptides
    Patent number: 6100069
    Abstract: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 20, 1998
    Date of Patent: August 8, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Katz, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong
  • Valyl tRNA synthetase from Staphylococcus aureus
    Patent number: 6090600
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: July 18, 2000
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Valyl tRNA synthetase from streptococcus pneumoniae
    Patent number: 6087142
    Abstract: The invention provides valS polypeptides and DNA (RNA) encoding valS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing valS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: July 11, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Becham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Cysteinyl-tRNA synthetase from Staphylococcus aureus
    Patent number: 6080717
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptides to screen for antibacterial compounds and methods for treatment of individuals having a need to inhibit tRNA synthetase polypeptides.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: June 27, 2000
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Cysteinyl TRNA synthetase from Streptococcus pneumoniae
    Patent number: 6074858
    Abstract: The invention provides cysS polypeptides and DNA (RNA) encoding cysS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing cysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: June 13, 2000
    Assignee: SmithKline Beecham Corporation
    Inventor: Elizabeth Jane Lawlor