Patents by Inventor Elizabeth Jane Lawlor

Elizabeth Jane Lawlor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histidyl tRNA synthetase from streptococcus pneumoniae
    Patent number: 6071731
    Abstract: The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: June 6, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Tyrosyl tRNA synthetase polynucleotides
    Patent number: 6071892
    Abstract: The invention provides tyrS polypeptides and DNA (RNA) encoding tyrS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tyrS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: June 6, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Elizabeth Jane Lawlor, John Edward Hodgson
  • Alanyl tRNA synthetase from Staphylococcus aureus
    Patent number: 6060294
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: May 9, 2000
    Assignee: SmithKline Beecham, p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Cysteinyl tRNA synthetase from Staphylococcus aureus
    Patent number: 6057138
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 15, 1998
    Date of Patent: May 2, 2000
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Glycyl tRNA synthetase from streptococcus pneumoniae
    Patent number: 6051412
    Abstract: The invention provides glyS (beta) and glyS (alpha) polypeptides and DNA (RNA) encoding glyS (beta) and glyS (alpha) polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glyS (beta) and glyS (alpha) polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: April 18, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Leucyl tRNA synthetase from Streptococcus pneumoniae
    Patent number: 6048716
    Abstract: The invention provides leuS polypeptides and DNA (RNA) encoding leuS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing leuS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: April 11, 2000
    Assignees: SmithKline Beecham Corp., SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Tryptophanyl tRNA synthetase, trpS, of Streptococcus pneumoniae
    Patent number: 6046174
    Abstract: The invention provides trpS polypeptides and DNA (RNA) encoding trpS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing trpS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: April 4, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Daniel Robert Gentry, Rebecca Claire Greenwood, Elizabeth Jane Lawlor
  • Histidyl tRNA synthetase from Streptococcus pneumoniae
    Patent number: 6040162
    Abstract: The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: March 21, 2000
    Assignee: Smithkline Beecham Corporation
    Inventors: Daniel Robert Gentry, Rebecca Claire Greenwood, Elizabeth Jane Lawlor
  • Asparaginyl tRNA synthetase from streptococcus pneumoniae
    Patent number: 6040163
    Abstract: The invention provides asnS polypeptides and DNA (RNA) encoding asnS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing asnS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: March 21, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • DNA encoding serS polypeptides
    Patent number: 6008021
    Abstract: The invention provides serS polypeptides and DNA (RNA) encoding serS polypeptide and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing serS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: December 28, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Methionyl tRNA synthetase polynucleotides
    Patent number: 6001601
    Abstract: The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: December 14, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Leucyl tRNA synthetase from staphylococcus aureus
    Patent number: 5994111
    Abstract: The invention provides novel tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: November 30, 1999
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding spo-rel polypeptides
    Patent number: 5989864
    Abstract: Spo-rel polypeptides and DNA (RNA) encoding such spo-rel and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spo-rel for the treatment of infection, particularly bacterial infections. Antagonists against such spo-rel and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spo-rel nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding the relA/spoT gene family and for detecting the polypeptide in a host.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: November 23, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Martin Karl Russel Burnham, Daniel Robert Gentry, John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding seryl t-RNA synthetase
    Patent number: 5968777
    Abstract: The invention provides serS polypeptides and DNA (RNA) encoding serS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing serS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: October 19, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Daniel Robert Gentry, Rebecca Claire Greenwood, Elizabeth Jane Lawlor
  • Arginyl tRNA synthetase from staphyloccus aureus
    Patent number: 5965416
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: October 12, 1999
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Threonyl tRNA synthetase polynucleotides
    Patent number: 5958733
    Abstract: The invention provides thrS polypeptides and DNA (RNA) encoding thrS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing thrS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: September 28, 1999
    Assignee: SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Polynucleotides encoding gluS polypeptides of streptococcus pneumoniae
    Patent number: 5958734
    Abstract: The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: September 28, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Prolyl tRNA synthetase polynucleotides
    Patent number: 5952196
    Abstract: The invention provides proS polypeptides and DNA (RNA) encoding proS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing proS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: September 14, 1999
    Assignee: SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Phenylalanyl-tRNA synthetase from Staphylococcus aureus
    Patent number: 5948657
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly baterial infections.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: September 7, 1999
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Seryl tRNA synthetase from Staphylococcus aureus
    Patent number: 5932461
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: August 3, 1999
    Assignee: SmithKline Beecham, plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor