Abstract: The invention provides methods, apparatuses, and compositions for high-throughput amplification sequencing of specific target sequences in one or more samples. In some aspects, barcode-tagged polynucleotides are sequenced simultaneously and sample sources are identified on the basis of barcode sequences. In some aspects, sequencing data are used to determine one or more genotypes at one or more loci comprising a causal genetic variant.

Abstract: The present invention is a class of highlighting devices that contain radiocontrast agents and a carrier medium. These devices may be used to highlight, mark, identify, or map external, but radiotransparent or radiolucent structures so that they are indicated in x-ray radiographic images.

Abstract: Provided herein are methods, systems, and devices for genetic screening. The genetic screening of two or more individuals can be utilized to predict the phenotype of a child from the group of individuals. Also disclosed is prediction of a phenotype of a child from a subset of biological relatives, such as a potential mother and father, before conception. In many instances, the methods, systems and devices herein are utilized to predict the probability of a child developing a rare genetic disease.

Abstract: A system is provided for easily and efficiently managing a compliance monitoring process and for dynamically generating an inspection report. The system includes a database that contains data that identifies specific information about a device, system or environmental element that is located and to be inspected at a particular site. The database also contains data that identifies specific information to be obtained during an inspection of the specific devices, systems or environmental elements at a particular site. Furthermore, the database can be easily updated to correspond with changes in the laws and/or regulations applicable to a particular site, or to correspond with changes to the devices, systems or environmental elements located at a particular site. The inspection report includes the data from the database, and is dynamically generated soon before an inspector inspects a device, system or environmental element at a particular site.

Abstract: A method and system of identifying individual aerosol particles in real time. Sample aerosol particles are compared against and identified with substantially matching known particle types by producing positive and negative test spectra of an individual aerosol particle using a bipolar single particle mass spectrometer. Each test spectrum is compared to spectra of the same respective polarity in a database of predetermined positive and negative spectra for known particle types and a set of substantially matching spectra is obtained. Finally the identity of the individual aerosol particle is determined from the set of substantially matching spectra by determining a best matching one of the known particle types having both a substantially matching positive spectrum and a substantially matching negative spectrum associated with the best matching known particle type.

Abstract: A method and system of identifying individual aerosol particles in real time. Sample aerosol particles are compared against and identified with substantially matching known particle types by producing positive and negative test spectra of an individual aerosol particle using a bipolar single particle mass spectrometer. Each test spectrum is compared to spectra of the same respective polarity in a database of predetermined positive and negative spectra for known particle types and a set of substantially matching spectra is obtained. Finally the identity of the individual aerosol particle is determined from the set of substantially matching spectra by determining a best matching one of the known particle types having both a substantially matching positive spectrum and a substantially matching negative spectrum associated with the best matching known particle type.

Abstract: A network security system provides a complete, reactive, Network Intrusion Detection System (NIDS) designed to stop a would-be hacker from gaining unauthorized access by blocking their connectivity to a protected network at the first sign of malicious activity. The network security system utilizes a commercially available or open source NIDS that can detect patterns in TCP/IP activity as well as examining packet headers to detect probes and attempts to compromise systems. The network security system then modifies the return route from the “victim” protected network so that outbound packets are never returned to the attacker.

Abstract: A test kit for determining the “volatile ammonia content” of biological samples comprising any wet or dry compost, manure, plasma or soil sample. The kit includes a transparent container for holding the sample, and a reactant chemistry gel system, located within the container in the space not occupied by the sample. The reactant mass includes an acidic pH reactant material, and a color change indicator material, responsive to pH changes in the reactant material. Ammonia vapors diffuse into the reactant material, reacting chemically with the acidic pH reactant material so as to produce a color change. The nature of the color change is an indication of the quantity of NH3 in the test-jar atmosphere, which in combination with the known pH of the sample, indicates the total ammonium in the biological sample.

Abstract: An ultrasound imaging probe assembly (2) has control cables (13, 14) extending along an inner core (5) of a cable assembly (1), an ultrasound imaging transducer assembly (1') connected with signal transmitting conductors (10) in the inner core (5), the cable assembly (1) having a compression resistant armor (6) slidably receiving the inner core (5), the inner core (5) having respective sheaths (11) receiving the control cables (13, 14) and the signal transmitting conductors (10) in the inner core (5) urge the control cables (14) along respective orthogonal axes centered on a central axis of the cable assembly (1).

Abstract: An ultrasound imaging probe assembly (3) has articulation control cables (4) and a rotating cable (6) enclosed by sheaths (16) in a signal transmitting cable (40), and the sheaths (16) extend inside a portion of the cable (40) to contain insulated wires (51) that supply power to reversible motors (10, 10a) that drive the cables (4 and 6).

Abstract: In a multiple-board computer system, diagnostics are primarily performed by highly reliable microcontroller units (MCUs) on each processor (and memory) board. Operated separately from the board central processing units so that board failure will not prohibit diagnostic routines, the MCUs are serially connected to a bus separate from the main bus. Redundant diagnostic processor board MCUs constantly monitor the other MCUs and the serial bus, and oversee the operation of an MCUs on a malfunctioning board. In an alternate embodiment the diagnostic processor boards are replaced by a microcomputer serving as a monitor.