Abstract: An imaging agent for detecting analytes in a biological environment includes functionalized, silicon vacancy center-containing nanodiamonds. Individual nanodiamonds of the imaging agent include at least one silicon vacancy center. The at least one silicon vacancy center can emit light having a wavelength in a narrow band in response to illumination having any wavelength in a wide range of wavelengths. The nanodiamonds are functionalized to selectively interact with an analyte of interest. The nanodiamonds can additionally include other color centers, and the imaging agent can include a plurality of sets of nanodiamonds having detectably unique ratios of silicon vacancy centers to other color centers. The silicon vacancy centers in the nanodiamonds can have a preferred orientation enabling orientation tracking of individual nanodiamonds or other applications. A method for detecting properties of the analyte of interest by interacting with the imaging agent is also provided.

Abstract: A system for use with a drug delivery device includes a sensor unit and a deactivation unit operatively coupled to an output of the sensor unit and to a drug-retaining region of the drug delivery device, wherein the drug-retaining region contains a drug. The sensor unit is configured to detect a characteristic of a local environment and generate an output corresponding to a value of the detected characteristic. The deactivation unit is configured to render the drug ineffective when the output of the sensor unit satisfies a predetermined condition.

Abstract: A key fob includes a transceiver to send and receive signals, a memory to store a key fob identification (KFID), and a processor coupled to said transceiver and memory. The processor is to execute, along with a pairing device, an identification (ID) authenticated key agreement protocol based on the KFID to authenticate a pairing device and to generate a common secret encryption key known only by the processor and the pairing device. The Processor receives a control unit identification (CUID) encrypted by the pairing device with the common secret encryption key, execute along with the control unit associated with the CUID an ID authenticated key agreement protocol based on the CUID to authenticate the control unit, generates a second common secret encryption key known only by the processor and the control unit, and receives an operation key encrypted by the control unit with the second common secret encryption key.

Abstract: Devices are provided to automatically inject drugs or other payloads into or beneath skin. These devices include an injector configured to drive a hollow needle into the skin and subsequently to deliver the payload through the hollow needle. Applied suction acts to draw blood from the puncture formed in the skin through the hollow needle, into the device, and to a sensor, blood storage element, or other payload. In some examples, the blood is drawn through the hollow needle when the hollow needle is penetrating the skin. In some examples, these devices are additionally configured to retract the hollow needle from the skin and/or to perform some other functions. These devices can be wearable and configured to automatically access blood or deliver a payload into skin, for example, to operate at one or more points in time while a wearer of a device is sleeping.

Abstract: Devices are provided to automatically access blood from beneath or within skin. These devices include an injector configured to drive a needle into the skin and subsequently to retract the needle from the skin. These devices additionally include a seal to which suction is applied. To drive the needle into the skin, the needle is first driven through the seal, creating at least one hole in the seal. The suction applied to the seal acts to draw blood from the puncture formed in the skin by the needle, through the at least one hole in the seal, and to a sensor, blood storage element, or other payload. These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time while a wearer of a device is sleeping.

Abstract: An imaging agent for detecting analytes in an environment includes functionalized nanodiamonds and functionalized magnetic particles that can selectively interact with an analyte. Each functionalized nanodiamond contains at least one color center configured emit light in response to illumination. At least one property of the light emitted by the color centers is related to the proximity of the functionalized magnetic particles to the color centers. This property can be detected to determine that the functionalized nanodiamonds are proximate to the functionalized magnetic particles, to determine that the functionalized nanodiamonds and the functionalized magnetic particles are interacting with the analyte, or other applications. Devices and methods for detecting properties of the analyte by interacting with the functionalized nanodiamonds and functionalized magnetic particles are also provided.

Abstract: Embodiments described herein may relate to an unmanned aerial vehicle (UAV) navigating to a target in order to provide medical support. An illustrative method involves a UAV (a) determining an approximate target location associated with a target, (b) using a first navigation process to navigate the UAV to the approximate target location, where the first navigation process generates flight-control signals based on the approximate target location, (c) making a determination that the UAV is located at the approximate target location, and (d) in response to the determination that the UAV is located at the approximate target location, using a second navigation process to navigate the UAV to the target, wherein the second navigation process generates flight-control signals based on real-time localization of the target.

Abstract: Embodiments described herein may help to provide support via a fleet of unmanned aerial vehicles (UAVs). An illustrative medical-support system may include multiple UAVs, which are configured to provide support for a number of different situations. Further, the medical-support system may be configured to: (a) identify a remote situation, (b) determine a target location corresponding to the situation, (c) select a UAV from the fleet of UAVs, where the selection of the UAV is based on a determination that the selected UAV is configured for the identified situation, and (d) cause the selected UAV to travel to the target location to provide support.

Abstract: Embodiments described herein may help to provide support via a fleet of unmanned aerial vehicles (UAVs). An illustrative medical-support system may include multiple UAVs, which are configured to provide support for a number of different situations. Further, the medical-support system may be configured to: (a) identify a remote situation, (b) determine a target location corresponding to the situation, (c) select a UAV from the fleet of UAVs, where the selection of the UAV is based on a determination that the selected UAV is configured for the identified situation, and (d) cause the selected UAV to travel to the target location to provide support.

Abstract: Embodiments described herein may relate to an unmanned aerial vehicle (UAV) navigating to a target in order to provide medical support. An illustrative method involves a UAV (a) determining an approximate target location associated with a target, (b) using a first navigation process to navigate the UAV to the approximate target location, where the first navigation process generates flight-control signals based on the approximate target location, (c) making a determination that the UAV is located at the approximate target location, and (d) in response to the determination that the UAV is located at the approximate target location, using a second navigation process to navigate the UAV to the target, wherein the second navigation process generates flight-control signals based on real-time localization of the target.

Abstract: A method and apparatus for gesture interaction with an image displayed on a painted wall is described. The method may include capturing image data of the image displayed on the painted wall and a user motion performed relative to the image. The method may also include analyzing the captured image data to determine a sequence of one or more physical movements of the user relative to the image displayed on the painted wall. The method may also include determining, based on the analysis, that the user motion is indicative of a gesture associated with the image displayed on the painted wall, and controlling a connected system in response to the gesture.

Abstract: A display tile includes a display panel and a fused fiber bundle overlay. The display panel includes display pixels and a bezel surrounding the display pixels. The fused fiber bundle overlay includes an input side mounted adjacent to the display panel and optically aligned with the display pixels to receive image light, an emission side opposite the input side to emit the image light, and an array of fused fibers each extending from the input side to the emission side and each including an input end and an emission end. At least a portion of the fused fibers are tapered.

Abstract: A method for pairing a key fob with a vehicle is provided. A pairing device and a key fob execute an ID authenticated key agreement protocol based on a KFID to authenticate one another and to generate an encryption key DHKey1. The pairing device encrypts a control unit identification (CUID) with DHKey1. The pairing device transmits the encrypted CUID to the key fob. The key fob and a control unit executes an ID authenticated key agreement protocol based on the CUID to authenticate one another and to generate an encryption key DHKey2. The control unit encrypts an operation key with DHKey2 and transmits the encrypted operation key to the key fob.

Abstract: A key fob includes a transceiver to send and receive signals, a memory to store a key fob identification (KFID), and a processor coupled to said transceiver and memory. The processor is to execute, along with a pairing device, an identification (ID) authenticated key agreement protocol based on the KFID to authenticate a pairing device and to generate a common secret encryption key known only by the processor and the pairing device. The Processor receives a control unit identification (CUID) encrypted by the pairing device with the common secret encryption key, execute along with the control unit associated with the CUID an ID authenticated key agreement protocol based on the CUID to authenticate the control unit, generates a second common secret encryption key known only by the processor and the control unit, and receives an operation key encrypted by the control unit with the second common secret encryption key.

Abstract: An imaging agent for detecting analytes in an environment includes functionalized nanodiamonds and functionalized magnetic particles that can selectively interact with an analyte. Each functionalized nanodiamond contains at least one color center configured emit light in response to illumination. At least one property of the light emitted by the color centers is related to the proximity of the functionalized magnetic particles to the color centers. This property can be detected to determine that the functionalized nanodiamonds are proximate to the functionalized magnetic particles, to determine that the functionalized nanodiamonds and the functionalized magnetic particles are interacting with the analyte, or other applications. Devices and methods for detecting properties of the analyte by interacting with the functionalized nanodiamonds and functionalized magnetic particles are also provided.

Abstract: Embodiments described herein may help to provide support via a fleet of unmanned aerial vehicles (UAVs). An illustrative medical-support system may include multiple UAVs, which are configured to provide support for a number of different situations. Further, the medical-support system may be configured to: (a) identify a remote situation, (b) determine a target location corresponding to the situation, (c) select a UAV from the fleet of UAVs, where the selection of the UAV is based on a determination that the selected UAV is configured for the identified situation, and (d) cause the selected UAV to travel to the target location to provide support.

Abstract: Devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs.

Abstract: A system for needle-free drawing of blood is disclosed. A device can include an evacuated negative-pressure barrel with a membrane sealing an aperture at a distal end, and a housing affixed to a proximal end. An accelerator barrel can be positioned within the negative-pressure barrel and fixed to the housing, with an open proximal end in a chamber in the housing, and an open distal end aligned with the aperture. The chamber can be filled with pressurized gas, and a trigger valve can hydrostatically separate the chamber from the open proximal end of the accelerator barrel. A micro-particle positioned within the accelerator barrel can be accelerated to high speed by an abrupt surge of gas by releasing the trigger valve. The micro-particle can attain enough momentum to pierce the aperture membrane and penetrate adjacent dermal tissue. A resulting micro-emergence of blood can be drawn into the negative pressure barrel.

Abstract: A method and apparatus for generating dynamic signage using a painted surface display system is described. The method may include capturing image data with at least a camera of a painted surface display system. The method may also include analyzing the image data to determine a real-world context proximate to a painted surface, wherein the painted surface is painted with a photo-active paint. The method may also include determining electronic signage data based on the determined real-world context. The method may also include generating a sign image from the determined electronic signage data based on the determined real-world context, and driving a spatial electromagnetic modulator to emit electromagnetic stimulation in the form of the sign image to cause the photo active paint to display the sign image.

Abstract: A method and apparatus for gesture interaction with a photo-active painted surface is described. The method may include driving a spatial electromagnetic modulator to emit electromagnetic stimulation in the form of an image to cause photo-active paint to display the image. The method may also include capturing, with at least a camera of a painted surface display system, image data of the image displayed on the photo-active paint applied to a surface and a user motion performed relative to the image. The method may also include analyzing the captured image data to determine a sequence of one or more physical movements of the user relative to the image displayed on the photo-active paint. The method may also include determining, based on the analysis, that the user motion is indicative of a gesture, and driving the spatial electromagnetic modulator to update.