Abstract: A method comprises performing a pattern recognition process to determine a geometry of a superconducting quantum device comprising one or more Josephson junctions, determining, based on the geometry determined by the pattern recognition process, a laser beam illumination pattern for laser annealing the one or more Josephson junctions of the superconducting quantum device, and configuring a laser microscope to generate the laser beam illumination pattern.

Abstract: Define a plurality of qubit collision types and a plurality of constraints. For a group of qubits, use a computerized mixed-integer programming solver to, subject to the constraints, iteratively minimize collisions by minimizing a sum of products of weights multiplied by an amount of frequency collisions for given ones of the constraints of each one of the collision types. Output a frequency tuning plan for the group of qubits, based on the iterative minimization. Facilitate tuning physical qubits in accordance with the frequency tuning plan.

Abstract: With a computerized frequency plan generator, for each node in a quantum lattice: determine a list of possible frequencies subject to at least one of nearest neighbor and next nearest neighbor collision constraints; and assign a highest possible frequency; apply a collision cleaning routine to the quantum lattice with the assigned frequencies until at least one of a condition where there are no remaining collisions and a condition where collision count ceases to improve; and apply a frequency perturbation routine to the collision-cleaned quantum lattice to move apart at least one of a high-risk nearest neighbor collision and a high risk next nearest neighbor collision.

Abstract: A calibration process comprises performing laser annealing calibration operations on first Josephson junctions using different combinations of at least laser power settings and anneal times, determining junction resistance shifts of the first Josephson junctions as a result of the laser annealing calibration operations, and utilizing the determined junction resistance shifts of the first Josephson junctions to determine calibration data for configuring laser annealing operations for bidirectional laser tuning of second Josephson junctions corresponding to the first Josephson junctions.

Abstract: The present disclosure is directed to novel bispecific Fc fusion proteins with an IF-15 domain, an Interleukin-15 receptor alpha (IF-15R?) sushi domain, an Fc domain and a soluble PD-1 (sPD-1) variant domain, polynucleotides encoding said bispecific Fc fusion proteins, methods of making and using thereof.

Abstract: The present disclosure relates to extracellular vesicles comprising one or more antigens from a coronavirus (e.g., SARS-CoV-1 or SARS-CoV-2) and optionally an adjuvant. Also provided herein are methods for producing the EVs and methods for using the EVs to treat and/or prevent diseases or disorders, e.g., infectious diseases.

Abstract: A system comprises a prober unit, and a control unit. The prober unit comprises electrical probes. The control unit configured to: cause the prober unit to make contact between the electrical probes and contact pads of a target device; cause the prober unit to increment a contact overdrive by a specified amount to increase a contact pressure between the electrical probes and the contact pads of the target device; measure a contact resistance between the electrical probes and the contact pads of the target device, subsequent to incrementing the contact overdrive; compare the measured contact resistance with a contact resistance threshold; and determine whether to perform an electrical characterization measurement of the target device, based on a result of comparing the measured contact resistance with the contact resistance threshold.

Abstract: An apparatus comprises a memory configured to store program instructions and a processor operatively coupled to the memory to execute the program instructions to centrally manage a plurality of computer systems configured to respectively perform a laser annealing process on a plurality of quantum computing-based devices configured to function as a modular quantum device.

Abstract: Generate an initial tuning plan for a quantum computing device based on an initial screening; determine whether yield rate according to the initial tuning plan is acceptable, based on real-time analytics; facilitate carrying out tuning based on the initial tuning plan based on the determining indicating that the yield rate according to the tuning plan is acceptable; and repeat the determining and facilitating carrying out tuning steps based on tuning being incomplete and the yield rate according to the initial tuning plan being acceptable.

Abstract: An apparatus comprises optical apparatus, and electrical characterization apparatus. The optical apparatus and the electrical characterization apparatus comprise an integrated configuration to perform laser annealing operations for tuning junction resistances of superconducting tunnel junction devices on a quantum chip, and to perform in-situ resistance measurements to measure the junction resistances of the superconducting tunnel junction devices on the quantum chip.

Abstract: An optical microscope device comprises an optically integrated configuration of components for imaging a target device within a field of view of the optical microscope device, and for laser annealing the target device by generating a laser beam spot pattern from a laser beam received on an optical fiber from a remote laser source, and for controlling a duration of exposure of the laser beam spot pattern for laser annealing the target device.

Abstract: Identify a plurality of candidate quantum computing chips to be arranged in a multi-chip quantum processor. Generate a current optimized tuning plan for the arrangement of the plurality of candidate quantum computing chips in the multi-chip quantum processor. Obtain results of tuning in accordance with the optimized tuning plan from at least one tuning system. Carry out tuning yield assessment based on results of the obtained tuning results. Repeat the steps of obtaining results and carrying out tuning yield assessment, based on tuning being incomplete and the current optimized tuning plan remaining viable.

Abstract: A method for performing a calibration process comprises performing laser annealing operations on a set of test superconducting tunnel junction devices using different combinations of laser power and anneal time, determining junction resistance shifts of the test superconducting tunnel junction devices as a result of the laser annealing operations, and utilizing the determined junction resistance shifts of the test superconducting tunnel junction to determine calibration data for configuring laser annealing operations for laser tuning superconducting tunnel junction devices corresponding to the test superconducting tunnel junction devices.

Abstract: A method is disclosed for manufacturing a fuel cell that includes a membrane electrode assembly, a sealing frame surrounding the membrane electrode assembly, and bipolar plates. The method includes (i) placing a prepared membrane electrode assembly into a pre-designed mold, (ii) injecting a sealing material composed of a first component and a second component into the mold and cooling it to solidify thereby forming the sealing frame, wherein the sealing frame has an inner peripheral region and an outer peripheral region, and wherein the first component in the inner peripheral region has a first proportion different from a second proportion of the second component in the outer peripheral region, and (iii) assembling the bipolar plates on both sides of the membrane electrode assembly and the sealing frame. Also disclosed is a corresponding fuel cell which enables cost-effective and rapid mass production while improving moldability and mechanical strength.

Abstract: The present disclosure relates to extracellular vesicles (e.g., exosomes) comprising a biologically active molecule covalently linked to the extracellular vesicle via an optimized linker and an anchoring moiety, which may be useful as an agent for the prophylaxis or treatment of cancer or other diseases. Also provided herein are methods for producing the extracellular vesicles and methods for using the extracellular vesicles to treat diseases or disorders.

Abstract: The present disclosure relates to extracellular vesicles (EVs), e.g., exosomes, which can be rapidly modified to comprise an antigen of interest, and the uses of such EVs as vaccines for the treatment of wide range of diseases or disorders. Also provided herein are methods for preparing and manufacturing such EVs for use as vaccines.

Abstract: A method and apparatus for managing liquidity when processing transactions are disclosed. In some embodiments, the method is implemented by a computing device and comprises: receiving data for a plurality of transactions; continuously reading in and aggregating, with an aggregator implemented at least partially in hardware of the computing device, transactions to produce one or more netted currency positions based on a plurality of properties of the transactions and on a plurality of netting constraints; generating one or more tasks, using a trade generator implemented at least partially in hardware of the computing device, to route cash movements as one or more batched fund transfers based on one or more trading policies; and sending the one or more tasks via network communications to one or more entities to execute the batched fund transfers.

Abstract: Techniques regarding selectively tuning the operating frequency of superconducting Josephson junction resonators are provided. For example, one or more embodiments described herein can comprise a method that can include chemically altering a Josephson junction of a Josephson junction resonator via a plasma treatment. The method can also comprise selectively tuning an operating frequency of the Josephson junction resonator based on a property of the plasma treatment.

Abstract: A midsole for an article of footwear includes an embroidered structure partially embedded in an exterior surface portion of the midsole. A method of forming the midsole includes combining the embroidered structure with a polymer material in a molding process to form the midsole.

Abstract: A gas circuit control system of a pneumatic cardiopulmonary resuscitation pressing device comprises a gas control valve (3) communicating with a piston cylinder (2) of the pneumatic cardiopulmonary resuscitation pressing device, and a spool of the gas control valve (3) controls gas charging and discharging of the piston cylinder (2) when reciprocating; and at least one end of the spool of the gas control valve (3) is provided with a gas cavity, the gas cavity communicates with a gas source through a miniature electronic control valve (4), and the miniature electronic control valve controls gas charging and discharging of the gas cavity to drive the spool of the gas control valve (3) to reciprocate.