Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.

Abstract: An implantable medical device (IMD) includes a housing that is configured to enclose internal components including at least a processor and a power source. The housing defines two major surfaces that are generally parallel to each other and one or more channels that are each configured to receive a lead and electrically couple the respective lead to the internal components, where each of the channels extend substantially straight in to the housing along an axis generally parallel to the two major surfaces. The housing may be configured to be mounted to a cranium of a patient such that at least one of the two major surfaces approximates a curvature of the cranium. The IMD may include one or more funneling walls that define a rounded and smooth transition from a sidewall of the housing to a surface that defines one or more mouths to the channels.

Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a first housing portion, a second housing portion and a joint coupling the first housing portion to the second housing portion. A polymer seal is positioned in the joint in various embodiments. Other embodiments of an IMD housing are disclosed.

Abstract: An external medical device generates a drive signal inductively coupled to an implantable coil from an external coil. A regulator module coupled to the implantable coil generates an output signal in response to the inductively coupled signal and a feedback signal correlated to an amplitude of the inductively coupled signal. A signal generator receives the output signal for generating a therapeutic electrical stimulation signal. The control module adjusts the drive signal in response to the feedback signal to control the electrical stimulation signal.

Abstract: A method of charging a battery includes applying a charging voltage to a lithium-ion battery for a period of time after the battery is fully charged. The battery includes a positive electrode having a positive active material, a negative electrode having a negative active material, and an electrolyte. The negative active material includes a lithium titanate material and has a capacity that is less than that of the positive electrode. The charging voltage is greater than a fully charged voltage of the battery, and applying the charging voltage for the period of time is sufficient to cause a zero volt crossing potential of the battery to increase to above a decomposition potential of the positive active material.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: In some examples, a system includes one or more ultrasound transducers, one or more temperature sensors, a user interface, and one or more processors. The one or more processors are configured to control the one or more ultrasound transducers to deliver ultrasound to a target point of tissue of a patient to heat the target point of tissue, control the one or more temperature sensors to sense a temperature of other tissue of the patient proximate to the target point of tissue a plurality of times over a period of time after the target point of tissue has been heated, and present, via the user interface, information indicating flow of heat from the target point of tissue to the other tissue over the period of time based on the sensed temperatures to facilitate characterization of at least one of anatomy or function of the tissue.

Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.

Abstract: Devices, systems, and techniques are configured for cooling tissue during recharge of an implantable medical device (IMD) battery. In one example, a method includes charging, by an inductive charger, a rechargeable battery of an implantable medical device (IMD) within a patient, wherein the IMD comprises a housing that houses the rechargeable battery, and wherein a primary coil of the inductive charger is positioned above a region of skin of the patient proximate to the IMD. The example method further includes cooling, by a heat exchanger, the region of skin below a normal ambient surface temperature of the region of skin, wherein the heat exchanger is interposed between the primary coil and the region of skin.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: An external medical device generates a drive signal inductively coupled to an implantable coil from an external coil. A regulator module coupled to the implantable coil generates an output signal in response to the inductively coupled signal and a feedback signal correlated to an amplitude of the inductively coupled signal. A signal generator receives the output signal for generating a therapeutic electrical stimulation signal. The control module adjusts the drive signal in response to the feedback signal to control the electrical stimulation signal.

Abstract: A method for producing a battery includes providing a battery having a positive electrode, a negative electrode, and an electrolyte that includes a solvent and a salt. The capacity of the negative electrode is less than that of the positive electrode and the negative electrode includes an active material having an average potential versus a lithium reference electrode of greater than approximately 0.2 volts. The method also includes applying an initial charge to the battery at a voltage that is greater than a fully charged voltage of the battery for a sufficient amount of time to cause at least a portion of the solvent to undergo a reduction reaction. The step of applying an initial charge to the battery acts to increase the irreversible capacity loss of the battery during the initial charge and provides the battery with enhanced tolerance to deep discharge conditions.

Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.

Abstract: An external medical device generates a drive signal inductively coupled to an implantable coil from an external coil. A regulator module coupled to the implantable coil generates an output signal in response to the inductively coupled signal and a feedback signal correlated to an amplitude of the inductively coupled signal. A signal generator receives the output signal for generating a therapeutic electrical stimulation signal. The control module adjusts the drive signal in response to the feedback signal to control the electrical stimulation signal.

Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.

Abstract: In some examples, an implantable medical device includes an implantable housing, a neurostimulator within the housing, a plurality of electrodes, an implantable lead coupled to the housing, and an actuator formed with the housing. The implantable lead includes at least one electrode of the plurality of electrodes and one or more conductors coupling the at least one electrode to the neurostimulator. The actuator is configured to cause at least a portion of the implantable lead to deflect.

Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.

Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.

Abstract: In some examples, a system includes a flexible ultrasound device configured to be attached to an external surface of a patient proximate to an organ of the patient to deliver ultrasound configured to modulate nerve tissue of the patient at the organ. The system further comprises one or more sensors configured to sense one or more physiological parameters indicative of at least one of a symptom treatable by, or a side effect of, the neuromodulation, and processing circuitry configured to control the delivery of ultrasound during an ambulatory period of the patient, and monitor the least one of the symptom or the side effect during the ambulatory period, based on the one or more physiological parameters. The organ may be the spleen and the ultrasound may at least one of regulate the autoimmune system of the patient, or reduce an inflammation response of the patient.

Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a first housing portion, a second housing portion and a joint coupling the first housing portion to the second housing portion. A polymer seal is positioned in the joint in various embodiments. Other embodiments of an IMD housing are disclosed.