Abstract: A protein transduction domain and a fusion compound, which are more efficient, are proposed. As a result of selecting and testing a number of candidate peptides, the present inventors found that a GK1 peptide comprising 18 amino acids and a modified sequence obtained by replacing, adding, or deleting some sequences are bonded to high-molecular-weight materials such as proteins based on the basic sequence of the peptide, thus enabling the high-molecular-weight materials to smoothly penetrate into living bodies, for example, cells, tissues, or blood. A fusion compound, oligonucleotide, or vector using the same may be applied as a pharmaceutical composition for preventing or treating diseases.

Abstract: The present disclosure relates to a method for preparation of 1,4-cyclohexanedimethanol. According to the present disclosure, two step reduction reactions are conducted using terephthalic acid as starting material, and an isomerization process for increasing the rate of trans isomers of CHDA is introduced therebetween, thereby providing a method capable of stably preparing CHDM with high rate of trans isomers.

Abstract: This invention relates to a method for preparing 1,4-cyclohexanedimethanol (CHDM), more specifically to a method for preparing 1,4-cyclohexanedimethanol having a high rate of trans isomers without an isomerization reaction step, wherein two-step hydrogenation reactions and a purification step are conducted using terephthalic acid as starting material.

Abstract: This invention relates to a method for preparing 1,4-cyclohexanedimethanol(CHDM), more specifically to a method for preparing 1,4-cyclohexanedimethanol having a high rate of trans isomers without an isomerization reaction step.

Abstract: This invention relates to a method for preparing 1,4-cyclohexane dicarboxylic acid (CHDA). More specifically, this invention relates to a method for preparing 1,4-cyclohexane dicarboxylic acid having a high rate of trans isomers, without an isomerization reaction step.

Abstract: A reactor for nanoparticle production comprising a main chamber including a first nozzle to which raw material gas is supplied, a lens housing connected to the main chamber in a fluidly movable manner and including a second nozzle for supplying flushing gas to the lens housing, a lens mounted on the lens housing, a light source for irradiating a laser, which passes through the lens to reach the raw material gas in the main chamber, and a hood for discharging nanoparticles generated in the main chamber. A cross-sectional area of at least a part of the lens housing decreases along a direction facing the main chamber.

Abstract: The present disclosure relates to a method for producing 1,4-cyclohexanedimethanol (CHDM) and, more specifically, provides a method for producing 1,4-cyclohexanedimethanol having a high proportion of trans isomers even without including an isomerization step, by adjusting the content of 1,4-cyclohexane dicarboxylic acid (CHDA) which is a reactant.

Abstract: The present disclosure relates to an isomerization method of a cyclohexane dicarboxylic acid (CHDA) and, more specifically, to a method for preparing a trans-cyclohexane dicarboxylic acid (t-CHDA) from a cis-cyclohexane dicarboxylic acid (c-CHDA) by means of catalytic isomerization. Particularly, an embodiment of the present disclosure provides a method for preparing, in high efficiency and high yield and at a low cost, a CHDA having a high t-CHDA content from a CHDA mainly containing c-CHDA, by using an isomerization catalyst containing zirconia and having a BET specific surface area of 50 m2/g or more.

Abstract: The present invention relates to a peeling device of sheet material for peeling off graphite, and the peeling device of sheet material according to the present invention is characterized in that a specific microchannel is used to apply a shear force required to peel off graphite, and simultaneously, graphene itself is not ground and the discharge flow rate of the graphene dispersion increases to increase graphene preparation efficiency.

Abstract: Provided a high-pressure homogenizer comprising a channel module comprising a microchannel through which an object for homogenization passes, wherein the microchannel is provided with a first flow channel and a second flow channel sequentially arranged along the direction through which the object passes, the first flow channel is provided with a plurality of first baffles disposed so as to partition the microchannel into a plurality of spaces, the second flow channel is provided with a plurality of second baffles disposed so as to partition the microchannel into a plurality of spaces, and at least one of the first baffles is provided to be positioned between two adjacent second baffles.

Abstract: The present invention relates to a pharmaceutical composition for administration in combination with a drug that causes acidosis. Acidosis occurs due to disrupted acid-base balance caused in a case where a large amount of acid is produced and accumulated in the body. There are many cases where acidosis occurs as a side effect associated with drugs for treating various diseases, which poses problems. The pharmaceutical composition of the present invention not only allows the intended purpose, for which a drug that causes acidosis is administered, to be maintained but also has a remarkable effect in decreasing the concentration of acid accumulated in an organism due to administration of the drug that causes acidosis. Thus, the pharmaceutical composition is expected to be widely used in the fields of medicine and health.

Abstract: The present disclosure relates to a method for preparation of 1,4-cyclohexanedimethanol. According to the present disclosure, two step reduction reactions are conducted using terephthalic acid as starting material, and an isomerization process for increasing the rate of trans isomers of CHDA is introduced therebetween, thereby providing a method capable of stably preparing CHDM with high rate of trans isomers.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating acidosis. The pharmaceutical composition has a remarkable effect in decreasing the concentration of acid accumulated in an organism and thus is expected to be widely used in the fields of medicine and health.

Abstract: A semiconductor device includes at least one trench extending into a semiconductor substrate and lined with a gate dielectric layer; a dipole inducing layer covering a lowermost portion of the lined trench; a gate electrode covering the dipole inducing layer and filled in the lined trench; and doping regions, in the semiconductor substrate, separated from each other by the lined trench and separated from the dipole inducing layer.

Abstract: A semiconductor device includes: a semiconductor device, comprising: a bit line structure including a bit line contact plug, a bit line, and a bit line hard mask that are sequentially stacked over a substrate; a storage node contact plug that is spaced apart from the bit line structure; a conformal spacer that is positioned between the bit line and the storage node contact plug and includes a low-k material; and a seed liner that is positioned between the conformal spacer and the bit line and thinner than the conformal spacer.

Abstract: Provided a high-pressure homogenizer comprising a channel module comprising a microchannel through which an object for homogenization passes, wherein the microchannel is provided with a first flow channel and a second flow channel sequentially arranged along the direction through which the object passes, the first flow channel is provided with a plurality of first baffles disposed so as to partition the microchannel into a plurality of spaces, the second flow channel is provided with a plurality of second baffles disposed so as to partition the microchannel into a plurality of spaces, and at least one of the first baffles is provided to be positioned between two adjacent second baffles.

Abstract: The present invention relates to a capsule comprising a pigment and a method for producing the same. More specifically, the present invention relates to a capsule which comprises therein a pigment inside which is likely to be discolored due to external environment, and thereby can easily crack or break and cause color development when applied to the skin, while isolating the pigment from the external environment, and a method for producing the same.

Abstract: Provided is a preparation method for a cyclohexane dimethanol (CHDM), which can have a high trans content through particular conditions, additive addition, or reactant addition, which is controlled in a cyclohexane dicarboxylic acid (CHDA) hydrogenation reaction, and a cyclohexane dimethanol prepared thereby.

Abstract: The present disclosure relates to an encapsulation film, an organic electronic device comprising the same, and a method for manufacturing an organic electronic device using the same, and provides an encapsulation film which can form a structure capable of blocking moisture or oxygen introduced from the outside into the organic electronic device, thereby effectively releasing the heat accumulated in the organic electronic device and preventing the occurrence of deterioration of the organic electronic device.

Abstract: Provided is an isomerization method of cyclohexane dicarboxylic acid using zirconia or titania as an isomerization catalyst.