Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A hanger for a turbine engine can include a first surface confronting a cooling airflow, a second surface facing a heated airflow, and a third surface radially outward of the first surface. The hanger can also include a cyclonic separator with a dirty air inlet and a clean air outlet, as well as a cooling air circuit extending through the cyclonic separator.

Abstract: A method, system and computer program product for managing a calendar application. A need to optimize a calendar is identified. Furthermore, a period of time to optimize the calendar is received or identified. All the scheduled events (e.g., scheduled meetings) in the calendar are then selected during that period of time. The attendees, topics and flags, if any, for each of the selected scheduled events during the period of time are extracted. Prior collaborations with the user involving the extracted attendees and/or topics of the selected scheduled events are identified. Collaboration data (e.g., participants/senders/attendees, topics) is then extracted from the identified prior collaborations. A list of actions (e.g., delegate scheduled event to another user) is generated to be performed on a selected scheduled event based on the extracted collaboration data. The generated list of actions to be performed on the selected scheduled event is then presented to the user.

Abstract: Provided here are sensors characterized by strain-insensitivity, the sensors comprising: a sheet in electrical communication with a positive electrode and a negative electrode; wherein the sheet comprises: an electrically conductive primary layer in electrical communication with the positive electrode and the negative electrode; at least one active-sensing region comprising at least one sensor-portion of the primary layer and in electrical communication with the positive electrode and the negative electrode; wherein the sensor is configured to perform sensing during use at the at least one active-sensing region; and at least one perforated region having a perforation design configured to provide for the sensor's strain-insensitivity.

Abstract: The present invention provides Ras modulators including inhibitors and/or antagonists of Ras, Ras binding, and Ras-dependent cell signaling activity. Also provided are methods of utilizing the Ras modulators as therapeutics.

Abstract: An apparatus and method for a component for a turbine engine, which generates a hot gas flow, and provides a cooling fluid flow, comprising a wall separating the hot gas flow from the cooling fluid flow and having a heated surface along which the hot gas flows and a cooled surface facing the cooling fluid flow and at least one cooling hole comprising a connecting passage extending between an inlet at the cooled surface and an outlet located at the heated surface, with the connecting passage comprising a diffusing section.

Abstract: Technologies are described image a treatment area during laser treatment using a time-gated image capture device and an electronic display. During laser treatment, a physician may monitor a treatment area to ensure efficacy and to prevent over-treatment. Light reflected from the area that includes treatment area may be detected by an image capture component and converted to a signal. An image processor may then generate image data based on the signal and provide the image data to be displayed on an electronic device. A gating component may send instructions to the image capture component and/or the image processor to prevent inclusion of light from one or more laser pulses generated during treatment. Excluding light from the laser pulses may prevent glare in captured images allow a monitoring physician to safely and accurately monitor the treatment area.

Abstract: A beverage can end has an arcuate panel wall and a chuck wall having a curved transition wall portion. Configuration of the seaming panel and panel wall is provided.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: Apparatuses for controlling gas flow are important components for delivering process gases for semiconductor fabrication. These apparatuses for controlling gas flow frequently rely on flow restrictors which can provide a known flow impedance of the process gas. In one embodiment, a flow restrictor is disclosed, the flow restrictor constructed of a plurality of layers, one or more of the layers having a flow passage therein that extends from a first aperture at a first end of the flow restrictor to a second aperture at a second end of the flow restrictor.

Abstract: Apparatuses for controlling gas flow are important components for delivering process gases for semiconductor fabrication. These apparatuses for controlling gas flow frequently rely on effectively sealed flow restrictors which can eliminate leakage of process gas around the flow restrictors. In one embodiment, a seal for a flow restrictor is disclosed, the seal comprising a plastic cylinder which is shrink fit onto a sealing portion of the flow restrictor. In another embodiment, a seal for a flow restrictor is disclosed, the seal having a first sealing ring with a flow aperture, a flow restrictor installed into the flow aperture.

Abstract: A method, system and computer program product for managing a calendar application. A need to optimize a calendar is identified. Furthermore, a period of time to optimize the calendar is received or identified. All the scheduled events (e.g., scheduled meetings) in the calendar are then selected during that period of time. The attendees, topics and flags, if any, for each of the selected scheduled events during the period of time are extracted. Prior collaborations with the user involving the extracted attendees and/or topics of the selected scheduled events are identified. Collaboration data (e.g., participants/senders/attendees, topics) is then extracted from the identified prior collaborations. A list of actions (e.g., delegate scheduled event to another user) is generated to be performed on a selected scheduled event based on the extracted collaboration data. The generated list of actions to be performed on the selected scheduled event is then presented to the user.

Abstract: A mass flow control apparatus having a monolithic base. The monolithic base has a gas inlet, a gas outlet, a first flow component mounting region, a second flow component mounting region, and a third flow component mounting region. The first flow component mounting region has a first inlet port and a first outlet port, the first inlet port being fluidly coupled to the gas inlet of the monolithic base. The third flow component mounting region has a first sensing port fluidly coupled to the gas outlet of the monolithic base.

Abstract: Pin probes and pin probe arrays are provided that allow electric contact to be made with selected electronic circuit components. Some embodiments include one or more compliant pin elements located within a sheath. Some embodiments include pin probes that include locking or latching elements that may be used to fix pin portions of probes into sheaths. Some embodiments provide for fabrication of probes using multi-layer electrochemical fabrication methods.

Abstract: Methods, devices and systems are provided for harmonizing output display characteristics of one component with those of other components onboard a vehicle, such as an aircraft. A line-replaceable unit (LRU) suitable includes a display driver to be coupled to a display command bus, a data storage element to maintain calibration information for the display driver, and a control module coupled to the display driver and the data storage element to identify a current state of an input command signal from the display command bus, identify an adjustment for the display driver based on the calibration information using the current state of the input command signal, and automatically operate the display driver in accordance with the adjustment.

Abstract: Technologies are generally described for replayable hacktraps for intruder capture with reduced impact on false positives. An example system may generate a replayable set of actions such as scripts and/or file system differences upon detecting the actions being forwarded to a deception network as potentially malicious actions. If the actions are determined not to be malicious, they may be executed on the protected network. Retroactively executing sequestered actions may allow deception countermeasures to be made more aggressive because false positive detections may have fewer negative impacts.

Abstract: A single plant which comprises a differential altitude and distributed root system; a foliage system; and at least one stem connecting between said root system and said foliage system. Methods of making same. Living facade including same.

Abstract: The present invention relates to methods of drug-assisted psychotherapy with cathinone, particularly methods employing 3-methyl methcathinone (3-MMC). The present invention also relates to kits comprising 3-MMC for use in the treatment of subjects undergoing psychotherapeutic intervention. In particular, methods and kits for drug-assisted psychotherapy with 3-MMC for a variety of disorders and/or conditions, including PTSD, GAD and relationship distress are provided.

Abstract: An apparatus and method for cooling an airfoil tip for a turbine engine can include an airfoil, such as a cooled turbine blade, having a tip rail extending beyond a tip wall enclosing an interior for the airfoil at the tip. A plurality of cooling holes can be provided in the tip rail at the tip. A flow of cooling fluid can be provided through the cooling holes from the interior of the airfoil to cool the tip of the airfoil.

Abstract: Technologies are generally described for normalized standard deviation transition based dosimetry monitoring for laser treatment. In some examples, a response signal may be generated based on a physical response to a laser pulse detected through acoustic or optical means. Each response signal may be a time series of data with a number of points. Standard deviation may be determined for each response signal and normalized using a mean or comparable normalization factor. Thus, a robust distribution may be computed from the response to each laser pulse. A change in the normalized standard deviation from each single pulse's time domain response data may be used to determine how many laser pulses remain before completion of the treatment (similar to event onset response). Thus, laser treatment may be continued based on an estimation of remaining pulses for completion or ceased if completion is reached.