Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths.

Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths.

Abstract: Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.

Abstract: Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.

Abstract: The present invention provides a general purpose controller chip that can be used for remotely monitoring and/or controlling plurality of devices that require current and/or voltage adjustment. In an embodiment, the general purpose controller chip is capable of performing multiple algorithmic functions such as monitoring current and voltage, adjusting and controlling them, switching power, performing detection algorithms, such as arc detection, LED dimming and the like, as well as communication functions. The general purpose controller chip provides a significantly higher level of integration and thereby makes the design of the devices simpler and dramatically reduces the cost of implementation, while providing ease of maintenance.

Abstract: Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.

Abstract: Interchangeable inserts are disclosed for use in enclosures, such as underground enclosures. The interchangeable inserts include insert bodies that are configured to house stand-alone nuts and nuts contained within removable trays.

Abstract: Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.

Abstract: The present disclosure relates to compositions comprising anti-viral therapeutics and methods of use thereof in killing parasites. Also described are methods of treating a parasitic infection; methods of screening a library for compounds effective in treating parasitic infections; and methods of diagnosing a parasitic infection.

Abstract: Interchangeable inserts are disclosed for use in enclosures, such as underground enclosures. The interchangeable inserts include insert bodies that are configured to house stand-alone nuts and nuts contained within removable trays.

Abstract: Enclosures are disclosed for use in underground applications. The enclosures include walls with end portions that are angled outward with respect to a middle of the wall such that the enclosures can be stacked on top of one another despite a draft angle of the walls. The bottom corners of the enclosures are aligned with a top surface of the enclosure to allow stacking. The enclosures include an opening in the bottom such that when multiple enclosures are stacked on top of one another, the enclosures for a single larger enclosure that can be used in underground applications.

Abstract: There is presented a spectroscopic apparatus and method wherein an input light source that inputs pump light to a photon pair source. The photon pair source converts pump photons into signal and idler photon pairs. The photon pair source is, in some of examples described herein, tuneable so that the wavelength of the signal and idler photons can be changed by application of a tuning means. At least one of the signal and idler photons is made incident upon a medium under test. A heralding detection apparatus is used to detect any signal and idler photons output from the spectroscopy apparatus, wherein at least one of the photons of the pair has interacted with or been operated upon by the medium under test.

Abstract: The present invention provides a general purpose controller chip that can be used for remotely monitoring and/or controlling plurality of devices that require current and/or voltage adjustment. In an embodiment, the general purpose controller chip is capable of performing multiple algorithmic functions such as monitoring current and voltage, adjusting and controlling them, switching power, performing detection algorithms, such as arc detection, LED dimming and the like, as well as communication functions. The general purpose controller chip provides a significantly higher level of integration and thereby makes the design of the devices simpler and dramatically reduces the cost of implementation, while providing ease of maintenance.

Abstract: There is presented a spectroscopic apparatus and method wherein an input light source that inputs pump light to a photon pair source. The photon pair source converts pump photons into signal and idler photon pairs. The photon pair source is, in some of examples described herein, tuneable so that the wavelength of the signal and idler photons can be changed by application of a tuning means. At least one of the signal and idler photons is made incident upon a medium under test. A heralding detection apparatus is used to detect any signal and idler photons output from the spectroscopy apparatus, wherein at least one of the photons of the pair has interacted with or been operated upon by the medium under test.

Abstract: Methods and apparatus for operating a remote controlled device according to various aspects of the present invention may comprise inputting a command into a controller, transmitting the command to the server and relaying the command to the remote controlled device.

Abstract: A screed corner comprises a screed base including substantially perpendicular nailing flanges and a bead leg extending away from each nailing flange. The bead has a horizontally disposed V-shaped cross section. A separate screed corner component is provided to be secured to arms of the bead and to close a gap in the screed base which is located in a volume comprising an intersection of a projection of each bead leg. The screed corner may be provided in a contour in sheet metal which can be readily bent to form a screed base. The screed corner component may comprise formed sheet metal. The corner component may comprise a sharp corner or may comprise a radius at its periphery. In one further form, the bead may comprise a substantially planar surface extending away from the nailing flange. In another, further form, the screed corner may be molded.

Abstract: A screed corner comprises a screed base including substantially perpendicular nailing flanges and a bead leg extending away from each nailing flange. The bead has a horizontally disposed V-shaped cross section. A separate screed corner component is provided to be secured to arms of the bead and to close a gap in the screed base which is located in a volume comprising an intersection of a projection of each bead leg. The screed corner may be provided in a contour in sheet metal which can be readily bent to form a screed base. The screed corner component may comprise formed sheet metal. The corner component may comprise a sharp corner or may comprise a radius at its periphery. In one further form, the bead may comprise a substantially planar surface extending away from the nailing flange. In another, further form, the screed corner may be molded.

Abstract: A multi-ply, expanded content wrap label includes a base ply and an upper ply thereon with adhesive applied to the underside of a trailing end of the base ply to form a splice between the base ply and the upper side of the upper ply when the label is applied to a container.

Abstract: A multi-ply, expanded content wrap label includes a base ply and an upper ply thereon with adhesive applied to the underside of a trailing end of the base ply to form a splice between the base ply and the upper side of the upper ply when the label is applied to a container.

Abstract: A multi-ply, expanded content wrap label includes a base ply and an upper ply thereon with adhesive applied to the underside of a trailing end of the base ply to form a splice between the base ply and the upper side of the upper ply when the label is applied to a container.