Patents by Inventor Fabrice Piu

Fabrice Piu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders
    Patent number: 8349353
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with cytotoxic agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: January 8, 2013
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Jeffrey P. Harris, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary
  • Controlled release antimicrobial compositions and methods for the treatment of otic disorders
    Patent number: 8318817
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: November 27, 2012
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Jeffrey P. Harris
  • Modulation of Gel Temperature of Poloxamer-Containing Formulations
    Publication number: 20120277199
    Abstract: Disclosed herein are methods for modulation of gel temperature of poloxamer-containing formulations. Also described herein are sustained release pharmaceutical formulations that gel upon contact with the body and are administered by direct application of these compositions and formulations onto or via perfusion into the targeted structure(s).
    Type: Application
    Filed: October 19, 2010
    Publication date: November 1, 2012
    Applicant: Otonomy, Inc.
    Inventors: Qiang Ye, Luis A. Dellamary, Fabrice Piu
  • Controlled-Release CNS Modulating Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20120190671
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: March 20, 2012
    Publication date: July 26, 2012
    Applicants: The Regents of the University of California, Otonomy, Inc.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319377
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Andrew M. Trammel, Sergio G. Durón, Fabrice Piu, Luis A. Dellamary, Qiang Ye, Carl Lebel, Michael Christopher Scaife, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319375
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Durón, Michael Christopher Scaife, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Andrew M. Trammel, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319373
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Andrew M. Trammel, Sergio G. Durón, Fabrice Piu, Luis A. Dellamary, Qiang Ye, Carl Lebel, Michael Christopher Scaife, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319374
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Durón, Michael Christopher Scaife, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Andrew M. Trammel, Jeffrey P. Harris
  • Controlled release corticosteroid compositions and methods for the treatment of OTIC disorders
    Patent number: 8030297
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: October 4, 2011
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Jeffrey P. Harris, Fabrice Piu, Carl Lebel, Qiang Ye, Luis A. Dellamary
  • COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS
    Publication number: 20110046237
    Abstract: Disclosed herein are methods of treatment and prevention of diseases and disorders related to estrogen receptors comprising administering novel di-aromatic compounds to patients in need thereof.
    Type: Application
    Filed: October 29, 2010
    Publication date: February 24, 2011
    Applicant: ACADIA PHARMACEUTICALS INC.
    Inventors: Roger OLSSON, Lene HYLDTOFT, Fabrice PIU, Magnus GUSTAFSSON, Vladimir SHERBUKHIN, Birgitte WINTHER LUND
  • Compounds with activity at estrogen receptors
    Patent number: 7825265
    Abstract: Disclosed herein are novel di-aromatic compounds and methods for using various di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: November 2, 2010
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Roger Olsson, Lene Hyldtoft, Fabrice Piu, Magnus Gustafsson, Vladimir Sherbukhin, Birgitte Winther Lund
  • CONTROLLED RELEASE AURIS SENSORY CELL MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100273864
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with auris sensory cell modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: April 26, 2010
    Publication date: October 28, 2010
    Applicant: OTONOMY, INC.
    Inventors: Jay LICHTER, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL
  • CONTROLLED RELEASE ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100036000
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 20, 2009
    Publication date: February 11, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED-RELEASE OTIC STRUCTURE MODULATING AND INNATE IMMUNE SYSTEM MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100021416
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with otic structure modulating compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 20, 2009
    Publication date: January 28, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED-RELEASE APOPTOSIS MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100016218
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with anti-apoptotic agent or pro-apoptotic agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 9, 2009
    Publication date: January 21, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice PIU, Qiang Ye, Luis A. Dellamary, Michael Christopher Scaife, Andrew M. Trammel, Jeffrey P. Harris
  • CONTROLLED RELEASE DELIVERY DEVICES FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100016450
    Abstract: Disclosed herein are delivery devices for use in the treatment of otic disorders wherein the delivery device is administered locally to an individual afflicted with an otic disorder, through direct application or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 21, 2009
    Publication date: January 21, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • CONTROLLED RELEASE AURIS SENSORY CELL MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100015263
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with auris sensory cell modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 16, 2009
    Publication date: January 21, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED RELEASE ION CHANNEL MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100015228
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with ion channel modulators. In these methods, the ion channel modulator compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the ion channel modulator compositions and formulations onto the auris interna target areas, or via perfusion into the auris interna structures.
    Type: Application
    Filed: July 21, 2009
    Publication date: January 21, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED RELEASE CORTICOSTEROID COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100009952
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: May 14, 2009
    Publication date: January 14, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Michael Christopher SCAIFE, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Carl LEBEL, Andrew M. TRAMMEL, Jeffrey P. Harris
  • CONTROLLED RELEASE AURAL PRESSURE MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100004225
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with aural pressure modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: June 17, 2009
    Publication date: January 7, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Michael Christopher SCAIFE, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Carl LEBEL, Andrew M. TRAMMEL, Jeffrey P. HARRIS