Patents by Inventor Fang Hu

Fang Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220296785
    Abstract: A degradable regenerative medical material for promoting tissue in-situ regeneration and a preparation method therefor. The degradable regenerative medicine material is formed by means of chemically bonding Si, P, O and metallic elements containing calcium, and is a regular three-dimensional net structure the material of which having a nano-scale mesoporous structure is framework, and pores and micron-scale macropores that communicate with the pores are uniformly distributed in the regular three-dimensional net structure. The preparation method for the degradable regenerative medical material comprises the steps of mixing a sol, foaming, curing and calcining. The degradable regenerative medicine material has a huge specific surface area, powerful biological activity and high biological safety, has the effect of promoting cell proliferation, may induce the rapid regeneration of its own damaged tissue cells, and achieve an in-situ tissue repair function.
    Type: Application
    Filed: September 19, 2019
    Publication date: September 22, 2022
    Applicant: BEST LIFE REGENERATIVE MEDICINE TECHNOLOGY CO. LTD
    Inventors: Chuangzhou GUO, Fang HU, Yuexiu QIU, Xiaoli YU
  • Patent number: 11446345
    Abstract: The present disclosure provides therapeutic agents and uses thereof for drugs for treatment of tumors and/or cancers. The active ingredients of the therapeutic agents comprise an oncolytic virus that selectively replicate in tumor cells and comprise NK cells.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: September 20, 2022
    Assignee: HANGZHOU CONVERD CO., LTD.
    Inventors: Fang Hu, Lin Chen, Ronghua Zhao
  • Publication number: 20220292895
    Abstract: The present disclosure relates to a method for monitoring and alarming hydrogen leakage of a fuel-cell vehicle and a system thereof. The method comprises the steps of: acquiring the current hydrogen concentration of a fuel-cell vehicle; judging whether the current hydrogen concentration is 0, if not, acquiring the measured hydrogen concentration, the hydrogen pressure drop value and the normal pressure range generated when the current hydrogen concentration of the fuel-cell vehicle is 0; judging whether the hydrogen pressure drop value exceeds the normal pressure range, if so, determining the predicted hydrogen concentration according to the measured hydrogen concentration and the hydrogen pressure drop value; judging whether the predicted hydrogen concentration exceeds the hydrogen leakage alarm threshold, and if not, determining the hydrogen leakage and issuing an alarm.
    Type: Application
    Filed: May 9, 2022
    Publication date: September 15, 2022
    Inventors: Meilin Ren, Tianyou Wang, Fang Wang, Yuntang He, Dong Hao, Zhizhao Che, Zhen Lu, Cheng Wang, Chenshu Hu, Hao Lan
  • Publication number: 20220293597
    Abstract: A circuit structure is provided. The circuit structure may include a first die area including an output gate, a second die area including a circuit and an input gate and a die-to-die interconnect. The input gate may include a transistor. The circuit may be connected between the die-to-die interconnect and a gate region of the transistor. The circuit may include a PMOS transistor and an NMOS transistor. A first source/drain region of the PMOS transistor may be connected to a first source/drain region of the NMOS transistor and the die-to-die interconnect.
    Type: Application
    Filed: June 24, 2021
    Publication date: September 15, 2022
    Inventors: CHANG-FEN HU, SHAO-YU LI, KUO-JI CHEN, CHIH-PENG LIN, CHUEI-TANG WANG, CHING-FANG CHEN
  • Publication number: 20220244121
    Abstract: An apparatus for testing a pressure change rate of a component in an electro-pneumatic braking system of a commercial vehicle includes a pressure change rate test bench, a pneumatic loop configured to implement on-off control of air and detection on a pressure change rate of a tested component in an electro-pneumatic braking system of a commercial vehicle, a signal processing unit configured to acquire a pressure signal and a differential pressure signal and perform analog-digital conversion on the signals to provide signals recognizable by an upper controller and a lower execution component, and a control unit configured to communicate with the pneumatic loop and drive the components in the pneumatic loop to act by setting a control parameter to obtain test data of the tested component in the electro-pneumatic braking system of the commercial vehicle in the pneumatic loop.
    Type: Application
    Filed: April 20, 2022
    Publication date: August 4, 2022
    Applicant: Wuhan University Of Technology
    Inventors: Jian HU, Yi CHENG, Hanwei BAO, Fang YANG, Gangyan LI
  • Publication number: 20220216396
    Abstract: A memory device and a manufacturing method thereof are provided. The memory device includes a magnetic tunneling junction (MTJ) and a spin Hall electrode (SHE). The MTJ includes a free layer, a reference layer and a barrier layer lying between the free layer and the reference layer. The SHE is in contact with the MTJ, and configured to convert a charge current to a spin current for programming the MTJ. The SHE is formed of an alloy comprising at least one heavy metal element and at least one light transition metal element. The heavy metal element is selected from metal elements with one or more valence electrons filling in 5d orbitals, and the light transition metal element is selected from transition metal elements with one or more valence electrons partially filling in 3d orbitals.
    Type: Application
    Filed: November 4, 2021
    Publication date: July 7, 2022
    Inventors: Yen-Lin Huang, MingYuan Song, Chien-Min Lee, Shy-Jay Lin, Chi-Feng Pai, Chen-Yu Hu, Chao-Chung Huang, Kuan-Hao Chen, Chia-Chin Tsai, Yu-Fang Chiu, Cheng-Wei Peng
  • Patent number: 11357804
    Abstract: Provided is the use of selectively replicating oncolytic viruses in the preparation of immunostimulants for treatment of tumors and/or cancers, wherein the oncolytic viruses do not carry exogenous immunoregulatory genes.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: June 14, 2022
    Assignee: HANGZHOU CONVERD CO., LTD.
    Inventors: Ronghua Zhao, Yanjun Zheng, Fang Hu
  • Publication number: 20220180090
    Abstract: The present disclosure provides a neural network-based visual detection and tracking method of an inspection robot, which includes the following steps of: 1) acquiring environmental images of a dynamic background a movement process of the robot; 2) preprocessing the acquired images; 3) detecting human targets and specific behaviors in the images in the robot body, and saving the sizes, position information and features of the human targets with the specific behaviors; 4) controlling the orientation of a robot gimbal by using a target tracking algorithm to make sure that a specific target is always located at the central positions of the images; and 5) controlling the robot to move along with a tracked object. The neural network-based visual detection and tracking method of an inspection robot in the present disclosure has a quite high adaptive ability, achieves better detection and tracking effects on targets in a dynamic background scene.
    Type: Application
    Filed: June 16, 2021
    Publication date: June 9, 2022
    Inventors: Yongduan Song, Li Huang, Shilei Tan, Junfeng Lai, Huan Liu, Ziqiang Jiang, Jie Zhang, Huan Chen, Jiangyu Wu, Hong Long, Fang Hu, Qin Hu
  • Publication number: 20220171395
    Abstract: A method for obstacle detection and recognition for an intelligent snow sweeping robot is disclosed, comprising: 1) disposing ultrasonic sensors at a front end of the snow sweeping robot to detect distance information from an obstacle ahead; and disposing radar sensors at the front and rear of the snow sweeping robot to detect whether a creature suddenly approaches; 2) processing signals detected by each of the ultrasonic sensors and radar sensors, and calculating a forward distance of the snow sweeping robot; and 3) determining a snow cover extent of a working road, detecting a change of the distance from the obstacles, and recognizing the obstacles for conditions of an ultrasonic ranging variation ratio and a variation of the forward distance of the snow sweeping robot, a change of the signal detected by radar sensors, and a descriptive statistic of the snow cover extent within a specific time period.
    Type: Application
    Filed: July 22, 2021
    Publication date: June 2, 2022
    Applicant: Chongqing University
    Inventors: Yongduan Song, Ziqiang Jiang, Shilei Tan, Junfeng Lai, Huan Liu, Li Huang, Jie Zhang, Huan Chen, Hong Long, Fang Hu, Jiangyu Wu, Qin Hu, Wenqi Li
  • Publication number: 20220103660
    Abstract: A protocol processing method and apparatus, and a storage medium are provided. The method includes: carrying a leaf-transfer capability identifier in an RIFT protocol, the leaf-transfer capability identifier being configured to indicate that a first node that carries the leaf-transfer capability identifier supports other leaf nodes within a network to access the network through the first node.
    Type: Application
    Filed: January 21, 2020
    Publication date: March 31, 2022
    Inventors: Benchong XU, Fang HU, Huilai WANG
  • Publication number: 20210393686
    Abstract: A therapeutic agent comprising a nucleic acid and a TCR modified immune cell and use thereof. The therapeutic agent comprises a first composition comprising a first active ingredient and a second composition comprising a second active ingredient. The first active ingredient includes or contains a nucleic acid having a labeling polypeptide coding sequence for being introduced into a tumor cell and/or a cancer cell. The labeling polypeptide has one or more epitope polypeptides which can be presented on a surface of the tumor cell and/or cancer cell by MHC class I molecules. The second composition comprises a second active ingredient in a second pharmaceutically acceptable carrier and the second active ingredient comprises a T cell receptor modified immune cell which can specifically recognize and bind to the epitope polypeptide presented by MHC class I molecules. The therapeutic agent achieves synergistic treatment effect and provides a new route for tumor treatment.
    Type: Application
    Filed: August 26, 2019
    Publication date: December 23, 2021
    Inventors: Fang HU, Yafei HOU, Jipo SHENG, Xiankui TAN
  • Publication number: 20210322288
    Abstract: An oral care composition with silica and polyvinylpyrrolidone showing an increased in viscosity after a shear event, viscosity recovery, of at least about 1.5× within approximately 348 seconds. A low-water oral care composition with improved rheology. A low-water oral care composition that does not leak from a toothpaste tube if inverted. An oral care composition with low water, silica, surface active polymer, and optionally polyphosphate.
    Type: Application
    Filed: April 19, 2021
    Publication date: October 21, 2021
    Inventors: Larissa Azirbayeva, Jessica Ong Meza, Marco Caggioni, Matthew Frazier Laird, Yuri Volodymyrovych Roiter, Christopher Medley, Fang Hu, William Handy Hartt, Setareh Shahsavari
  • Patent number: 10980859
    Abstract: The invention provides an in vivo individualized systemic immunotherapeutic method and device. The method includes, in a non-sequential manner: (1) increasing release amount of tumor antigens at a tumor site; (2) at the tumor site, increasing level of proteins capable of adhering to and/or wrapping the tumor antigens; (3) at the tumor site, increasing level of dedicated antigen-presenting cells involved in immunity, and establishing, between the dedicated antigen-presenting cells and immune effector cells, a close connection capable of activating the immune effector cells; and (4) at the tumor site, increasing level and improving function of the immune effector cells. The steps (1)-(4) each reaches a maximum value at a respective time which overlaps with each other maximally, as well as at a respective site which overlaps with each other maximally. The invention combines oncolytic therapy and immunotherapy, in individualized systemic immunotherapy, and provides significantly improved therapeutic effect.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: April 20, 2021
    Assignee: Hangzhou Converd Co., Ltd.
    Inventors: Fang Hu, Ronghua Zhao, Siyi Chen, Bo Wu, Huiqun Xia, Yanjun Zheng
  • Publication number: 20200394937
    Abstract: The present invention discloses a simulation device for characterizing aerodynamics of dry powder inhalation in respiratory system comprising: a constant temperature-and-humidity chamber, a steam and vacuum generating device and a respiratory system model arranged in the constant temperature and humidity chamber, and the constant temperature and humidity chamber and the respiratory system model are both connected with the steam and vacuum generating device; a temperature and humidity sensor is arranged in the constant temperature-and-humidity chamber and electrically connected with the steam and vacuum generating device; the respiratory system model comprises an oral cavity receiver and sample collectors, wherein inner walls of the respiratory system model are coated with a coating, the sample collectors includes a first sample collector and a second sample collector, each of the collectors is provided with 8 collecting trays.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 17, 2020
    Inventors: Yongqi CHEN, Fang HU
  • Patent number: 10828397
    Abstract: Disclosed are a regenerative medical material for promoting the repair of soft and hard tissues, a preparation method therefor, and the use thereof. The regenerative medical material has a three-dimensional network structure and is a composite material composed of inorganics and organics, wherein the mass ratio of the inorganics to the organics is 2:1-4:1. Based on the total mass of the inorganics, the inorganics contain 12-38% SiO2, 3-5% Na2O, 15-29% CaO, 10-32.5% P2O5, 1-5% inositol hexaphosphate, 1-5% cyclohexanhexol phosphate, and the balance of impurities, with the content of impurities being less than 0.5%. Based on the total mass of the organics, the organics contain 30-60% carboxymethyl chitosan and 30-60% sodium hyaluronate. The regenerative medical material has a composition and properties better suited to the human body and plays a key role in cell repair and bonding, cell proliferation, and promoting the growth of hair follicles.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: November 10, 2020
    Inventor: Fang Hu
  • Publication number: 20200289567
    Abstract: A therapeutic agent and method of administering the therapeutic agent for the treatment of tumors and/or cancers of a subject, the therapeutic agent comprising a first pharmaceutical composition comprising a first active ingredient in a first druggable vehicle, wherein the first active ingredient comprises a nucleic acid encoding a labelling polypeptide comprising one or more antigenic epitope peptides and/or encoding a MHC protein; a second pharmaceutical composition comprising a second active ingredient in a second druggable vehicle, wherein the second active ingredient comprises immune cells purified from peripheral blood or from tumor tissue and are cultured in vitro; wherein the nucleic acid when administered to the subject as part of the pharmaceutical composition causes the tumor cells and/or cancer cells of the subject to express the one or more antigenic epitope peptides to elicit an immune response of the immune cells.
    Type: Application
    Filed: February 24, 2020
    Publication date: September 17, 2020
    Inventors: Yafei Hou, Fang Hu, Jipo Sheng, Xiankui Tan, Can Chen
  • Publication number: 20200289591
    Abstract: The invention provides an isolated recombinant oncolytic vaccinia virus, pharmaceutical compositions and uses thereof for drugs for treatment of tumors and/or cancers. The isolated recombinant oncolytic vaccinia virus is functionally deficient in the TK gene and the VGF gene, and the genome of the recombinant oncolytic vaccinia virus is integrated with an exogenous IL-21 gene, and wherein the IL-21 gene is capable of being expressed in tumor cells. The recombinant oncolytic vaccinia virus can selectively replicate in tumor cells, and can also fully exert the anti-tumor immune effect of the exogenous IL-21, such that the oncolytic killing effect of the oncolytic virus and the anti-tumor immune stimulation effect of IL-21 achieve a synergic effect.
    Type: Application
    Filed: June 28, 2018
    Publication date: September 17, 2020
    Inventors: Jin Fu, Ronghua Zhao, Rong Zhang, Tingting Wang, Lin Chen, Fang Hu
  • Publication number: 20200276252
    Abstract: The present disclosure provides an isolated recombinant oncolytic adenovirus, a pharmaceutical composition, and uses thereof for drugs for treatment of tumors and/or cancers. The recombinant oncolytic adenovirus is a selectively replicating oncolytic adenovirus, and the genome of the recombinant oncolytic adenovirus is integrated with a coding sequence of exogenous shRNA capable of inhibiting PDL1 expression in tumor cells. The replication capability of the virus in normal primary cells is much lower than the replication capability of the virus in tumor cells. Moreover, the expressed shPDL1 can significantly reduce the level of PDL1 protein highly expressed in tumor cells. Thus, the oncolytic killing effect of the oncolytic virus and the anti-tumor immunostimulatory effect of immune cells produce a synergistic effect.
    Type: Application
    Filed: July 3, 2018
    Publication date: September 3, 2020
    Inventors: Jipo SHENG, Jin FU, Ronghua ZHAO, Yun QIN, Lin CHEN, Sanmao KANG, Fang HU
  • Patent number: D901214
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: November 10, 2020
    Inventor: Fang Hu
  • Patent number: D914394
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: March 30, 2021
    Inventor: Fang Hu