Patents by Inventor Fang Xie

Fang Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7576205
    Abstract: A threading intercalator of general formula I: IG1-DG-IG2-(DG-IG3)n??(I) wherein IG1, IG2, and IG3 are the same or different and represent an intercalating group comprising a planar polyaromatic group; wherein DG represents an electrochemical, a chemiluminescent, a catalytic or an electrochemiluminescent detectable group; and wherein n represents 0 or 1. This invention also relates to a process of detecting a double strand nucleic acid molecule using the threading intercalator.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: August 18, 2009
    Assignee: Agency for Science, Technology & Research
    Inventors: Zhiqiang Gao, Hong Xie, Fang Xie
  • Patent number: 7563588
    Abstract: An electrically non-conductive, nanoparticulate membrane comprising nanoparticles of at least one inorganic oxide of an element selected from Group IA, IIA, IIIA, IVA, IB, IIB, IIIB, IVAB, VB, VIB, VIIB or VIIIB of the Periodic Table, and wherein an oxidoreductase enzyme and a polymeric redox mediator capable of transferring electrons are diffusibly dispersed in said nanoparticulate membrane.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: July 21, 2009
    Assignee: Agency for Science, Technology and Research
    Inventors: Zhiqiang Gao, Guolin Xu, Yi-Ru Jackie Ying, Mohamed Shariff Mohamed Arshad, Fang Xie
  • Publication number: 20090095726
    Abstract: Traditional temperature-control products have the problem that the temperature of the working surface reaches the setting temperature too slowly when heating up or recovering from a temperature drop. A traditional temperature control circuit and temperature-settings selector components are modified to solve this problem. When heating begins, the modified circuit increases the initial setting temperature to be above the target setting temperature. The modified circuit then adjusts the setting temperature by measuring the heating power consumption. Once the working surface of the temperature control product reaches the initial setting temperature, the heating power consumption drops and the modified circuit reduces the temperature setting to the target setting temperature. The temperature control product can rapidly achieve the target temperature. A positive-temperature-coefficient heating component is used in the temperature control product.
    Type: Application
    Filed: October 10, 2007
    Publication date: April 16, 2009
    Applicant: PERICOM TECHNOLOGY (SHANGHAI) CO. LTD.
    Inventors: Qun Song, Fang Xie, Qi Wu, Zeyu Huang
  • Patent number: 7479557
    Abstract: The invention is directed to a compound having the general formula (I): wherein each of La and Lb is an independently selected from a linking moiety comprising 0 to 10 main chain atoms, optionally substituted; each of Za and Zb is an independently selected complexing moiety comprising at least one nitrogen atom; either both or one of Za and/or Zb is coordinatively bonded to a respective transition metal complex MaVa and MbVb through said nitrogen atom, wherein each of Ma and Mb is an independently selected transition metal, and each of Va and Vb is an independently selected valence group.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: January 20, 2009
    Assignee: Agency for Science, Technology +Research
    Inventors: Zhiqiang Gao, Fang Xie
  • Publication number: 20090015316
    Abstract: A semiconductor integrated circuit (IC) acts as a controller of a heating-controlled device or appliance. A heating body has a positive temperature coefficient and acts as both a heating element and a temperature sensor. A Silicon-Controlled Rectifier (SCR) switches AC current to the heating body to increase its temperature. When the SCR switches off, temperature sensing is performed using a sampling resistor, isolation diode, voltage comparator, and switch for a low-voltage DC supply are formed on an integrated circuit that has a first circuit branch and a second circuit branch. A compensation diode and a compensation resistor can be added in parallel to reference resistors. The compensation diode compensates for the forward voltage drop of the isolation diode that would otherwise create an inaccurate temperature measurement. The diodes have the same temperature response, allowing for a more accurate temperature measurement over a full temperature range of the sensorless appliance.
    Type: Application
    Filed: July 13, 2007
    Publication date: January 15, 2009
    Applicant: PERICOM TECHNOLOGY (SHANGHAI) CO. LTD.
    Inventors: Qun Song, Qi Wang, Fang Xie, De-Song Huang, Qi Xu
  • Patent number: 7462720
    Abstract: Compositions and methods for electrochemical detection of nucleic acid are disclosed. The compositions comprise electrocatalytic intercalators that bind to double-stranded nucleic acid and oxidize nucleic acid. Methods of detecting nucleic acid in a sample comprise forming double-stranded nucleic acid that is bound by electrocatalytic intercalators wherein the intercalators catalyze oxidation of the nucleic acid at the surface of an electrode.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: December 9, 2008
    Inventors: Fang Xie, Hong Xie, Zhiqiang Gao
  • Publication number: 20080098111
    Abstract: An application portal selectively provides a user access to items of a plurality of remote applications. At least one of the items is related to more than one of the remote applications. An authorization layer is included in the portal and includes a map indicating that the user is permitted to access at least one of the items.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 24, 2008
    Applicant: Verizon Business Financial Management Corporation
    Inventors: Marcial Montes de oca, Chi-Hwei Julie Lin, Manuel Ledesma, Yunyan Wang, Fang Xie, Tsehsin Jason Liu
  • Publication number: 20070191263
    Abstract: Molecules comprising aminooxy groups are provided, wherein the aminooxy groups provide attachment sites for the covalent attachment of other molecules. In one embodiment, polyoxyethylene molecules comprising aminooxy groups are provided that can be conjugated to wide variety of biologically active molecules including poly(amino acids). In another embodiment, valency platform molecules comprising aminooxy groups are provided. The aminooxy groups can be used to form covalent bonds with biological molecules such as poly(amino acids). The aminooxy groups can, for example, react with poly(amino acids) modified to contain carbonyl groups, such as glyoxyl groups, to form a conjugate of the valency platform molecule and the biologically active molecule via an oxime bond. The valency platform molecules comprising aminooxy groups are advantageously reactive in the formation of conjugates, and they also can be readily synthesized to form a composition with very low polydispersity.
    Type: Application
    Filed: March 26, 2007
    Publication date: August 16, 2007
    Applicant: La Jolla Pharmaceutical Company
    Inventors: David Jones, Huong-Thu Ton-Nu, Fang Xie, Anping Tao, Tong Xu, Jeffrey Hammaker
  • Publication number: 20070042377
    Abstract: A sensor for determining the presence of an analyte in a test sample, said sensor comprising a nanoparticulate membrane comprising nanoparticles of at least one inorganic oxide of an element selected from Group IA, IIA, IIIA, IVA, IB, IIB, IIIB, IVAB, VB, VIB, VIII3 or VIIII3 of the Periodic Table, and wherein an oxidoreductase and an electrochemical activator are diffusibly dispersed in said nanoparticulate membrane.
    Type: Application
    Filed: October 25, 2004
    Publication date: February 22, 2007
    Inventors: Zhiqiang Gao, Guolin Xu, Yi-Ru Ying, Mohamed Mohemed Arshad, Fang Xie
  • Publication number: 20060281922
    Abstract: A threading intercalator of general formula I: IG1-DG-IG2-(DG-IG3)n ??(I) wherein IG1, IG2, and IG3 are the same or different and represent an intercalating group comprising a planar polyaromatic group; wherein DG represents an electrochemical, a chemiluminescent, a catalytic or an electrochemiluminescent detectable group; and wherein n represents 0 or 1. This invention also relates to a process of detecting a double strand nucleic acid molecule using the threading intercalator.
    Type: Application
    Filed: June 13, 2005
    Publication date: December 14, 2006
    Inventors: Zhiqiang Gao, Hong Xie, Fang Xie
  • Publication number: 20060160100
    Abstract: There is provided an electrochemical assay method for detecting a target molecule, for example a protein, in a sample, which involves the use of a protective monolayer and a redox polymer to form a bilayer immobilized on an electrode. The monolayer protects the electrode from non-specific adherence of reagents, particular proteins, to the electrode while simultaneously providing a surface that can be functionalized to immobilize a capture molecule and that can interact with the redox polymer.
    Type: Application
    Filed: January 19, 2005
    Publication date: July 20, 2006
    Inventors: Zhiqiang Gao, Ponnampalam Gopalakrishnakone, Van Le, Fang Xie
  • Publication number: 20060141597
    Abstract: Molecules comprising aminooxy groups are provided, wherein the aminooxy groups provide attachment sites for the covalent attachment of other molecules. In one embodiment, polyoxyethylene molecules comprising aminooxy groups are provided that can be conjugated to wide variety of biologically active molecules including poly(amino acids). In another embodiment, valency platform molecules comprising aminooxy groups are provided. The aminooxy groups can be used to form covalent bonds with biological molecules such as poly(amino acids). The aminooxy groups can, for example, react with poly(amino acids) modified to contain carbonyl groups, such as glyoxyl groups, to form a conjugate of the valency platform molecule and the biologically active molecule via an oxime bond. The valency platform molecules comprising aminooxy groups are advantageously reactive in the formation of conjugates, and they also can be readily synthesized to form a composition with very low polydispersity.
    Type: Application
    Filed: December 16, 2005
    Publication date: June 29, 2006
    Inventors: David Jones, Huong-Thu Ton-Nu, Fang Xie, Anping Tao, Tong Xu, Jeffrey Hammaker
  • Patent number: 7030257
    Abstract: Disclosed herein are novel high oxidation state metallocene compounds, processes for preparing these compounds and uses of these compounds.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: April 18, 2006
    Assignee: Agency for Science, Technology and Research
    Inventors: Zhiqiang Gao, Fang Xie, Hong Xie
  • Publication number: 20060046254
    Abstract: Compositions and methods for electrochemical detection of nucleic acid are disclosed. The compositions comprise electrocatalytic intercalators that bind to double-stranded nucleic acid and oxidize nucleic acid. Methods of detecting nucleic acid in a sample comprise forming double-stranded nucleic acid that is bound by electrocatalytic intercalators wherein the intercalators catalyze oxidation of the nucleic acid at the surface of an electrode.
    Type: Application
    Filed: September 2, 2004
    Publication date: March 2, 2006
    Inventors: Fang Xie, Hong Xie, Zhiqiang Gao
  • Publication number: 20050277120
    Abstract: The invention is directed to a compound having the general formula (I): wherein each of La and Lb is an independently selected from a linking moiety comprising 0 to 10 main chain atoms, optionally substituted; each of Za and Zb is an independently selected complexing moiety comprising at least one nitrogen atom; either both or one of Za and/or Zb is coordinatively bonded to a respective transition metal complex MaVa and MbVb through said nitrogen atom, wherein each of Ma and Mb is an independently selected transition metal, and each of Va and Vb is an independently selected valence group.
    Type: Application
    Filed: June 10, 2004
    Publication date: December 15, 2005
    Applicant: Agency for Science, Technology and Research
    Inventors: Zhiqiang Gao, Fang Xie
  • Publication number: 20050228189
    Abstract: Disclosed herein are novel high oxidation state metallocene compounds, processes for preparing these compounds and uses of these compounds.
    Type: Application
    Filed: April 13, 2004
    Publication date: October 13, 2005
    Applicant: Agency for Science, Technology and Research
    Inventors: Zhiqiang Gao, Fang Xie, Hong Xie
  • Patent number: 6369517
    Abstract: An electronic switch can replace a standard mechanical light switch for 110-240 volt alternating-current (A.C.) devices. A triac switches the A.C. current to an A.C. device such as a light. A rectifier bridge generates a direct-current (D.C.) voltage that is applied to a special current limiter. The special current limiter generates a large current peak at low voltages, but limits current at high voltages. The large current peak from the special current limiter charges a capacitor when voltage is low at the beginning of each A.C. half-cycle, before the triac turns on. The capacitor has enough charge to supply D.C. current to an Infrared detector and trigger control logic for the rest of the A.C. half-cycle. When the detector detects a person nearby, it signals the trigger control logic. The D.C. voltage from the rectifier bridge is filtered to generate a sync pulse to the trigger control logic when adds a phase delay to the sync pulse which triggers the triac.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: April 9, 2002
    Assignee: Pericom Technology (Shanghai) Co., Ltd.
    Inventors: Qun Song, Jian Li, Fang Xie
  • Publication number: 20020000758
    Abstract: An electronic switch can replace a standard mechanical light switch for 110-240 volt alternating-current (A.C.) devices. A triac switches the A.C. current to an A.C. device such as a light. A rectifier bridge generates a direct-current (D.C.) voltage that is applied to a special current limiter. The special current limiter generates a large current peak at low voltages, but limits current at high voltages. The large current peak from the special current limiter charges a capacitor when voltage is low at the beginning of each A.C. half-cycle, before the triac turns on. The capacitor has enough charge to supply D.C. current to an Infrared detector and trigger control logic for the rest of the A.C. half-cycle. When the detector detects a person nearby, it signals the trigger control logic. The D.C. voltage from the rectifier bridge is filtered to generate a sync pulse to the trigger control logic when adds a phase delay to the sync pulse which triggers the triac.
    Type: Application
    Filed: March 12, 2001
    Publication date: January 3, 2002
    Inventors: Qun Song, Jian Li, Fang Xie
  • Patent number: 5173460
    Abstract: This invention relates to a piezoelectric ceramic material of a quarternary system, formulated on the basis of ternary system materials (PCM and PMN). Said quarternary system piezoelectric ceramic material consists of lead niobate with Mg (Pb (Mg.sub.1/3 Nb.sub.2/3)O.sub.3, lead niobate with Mn (Pb(Mn.sub.1/3 Nb.sub.2/3)O.sub.3), lead zirconate (PbZrO3) and lead titanate (PbTiO3), and possesses excellent properties for large power output purposes, and is suitable for making piezoelectric transformers of large power output. A single piece piezoelectric transformer (dimensions 100.times.25.times.36 mm3) using the material of the present invention is found to have a maximum output power of 50 W. The material according to this invention has a simple preparing process, a wider and lower sintering temperature range, is fine and compact in ceramic structure, and has a high rate of success of finished products.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: December 22, 1992
    Assignee: Hubei University
    Inventors: An-Xiang Kuang, Tao-Shen Zhou, Chang-Xin He, Li-Ying Chai, Ju-Fang Xie