Abstract: A multi-sensor non-invasive blood glucose monitoring instrument based on impedance spectroscopy-optical method, which belongs to a blood glucose measuring instrument for human body. The blood glucose monitoring instrument comprises a detection probe, a microprocessor, a display unit and a storage unit. The detection probe comprises a temperature and humidity sensor, an LED array, a photoelectric sensor, a pair of low-frequency electrodes, and a pair of high-frequency electrodes. The high-frequency electrode employs parallel electrodes, a matching inductor is directly soldered to the positive electrode or negative electrode of the electrode, and a shielding electrode is provided around the high-frequency electrode. The distance between the two low-frequency electrodes is 1 cm-2 m, and the low-frequency electrodes can test the low-frequency impedance of the tissue stably.

Abstract: The present invention relates to a crystal of cephalosporin intermediate 7?-methoxy cephalothin (I) and a method for preparing same. The crystal of 7?-methoxy cephalothin (I) undergoes Cu-Ka radiation and X-ray powder diffraction expressed in terms of angle 2?; the crystal of 7?-methoxy cephalothin (I) has characteristic absorption peaks at positions of 7.34°±0.20°, 12.71°±0.20°, 14.25°±0.20°, 14.68°±0.20°, 16.52°±0.20°, 17.99°±0.20°, 19.98°±0.20°, and 22.69°±0.20°. The crystal of 7?-methoxy cephalothin provided by the present invention is easy to prepare. Related test data shows that the crystal of 7?-methoxy cephalothin has high purity, low impurity content, and good stability. The preparation cost is low, the preparation method is simple to operate, conditions are mild and easy to control, and crystals of 7?-methoxy cephalothin can be obtained stably. The invention is applicable to industrial production.

Abstract: The present invention discloses a universal non-invasive blood glucose estimation method based on time series analysis, which comprises 5 steps, i.e., data input and preprocessing, features screening, establishment of single-feature model based on time series analysis, multi-feature fusion, and non-invasive blood glucose estimation. During non-invasive blood glucose estimation, new non-invasive test data is inputted, and the blood glucose estimation series is calculated using related feature information obtained through modeling, single-feature model, and multi-feature fusion model. The estimation method provided in the present invention is easy to execute, and can overcome the delay between changes of physiological parameters of human body and changes of blood glucose, and thereby can obtain more accurate non-invasive blood glucose test results. The estimation method is universal and is applicable to different non-invasive blood glucose monitoring methods.

Abstract: This invention relates to cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) protein compositions and their use in the mitigation of autoimmune adverse events associated with cancer immunotherapy. Specifically, the disclosure provides a CTLA-4 protein comprising a mutant extracellular domain of CTLA-4, wherein the CTLA-4 protein exhibits reduced binding to an anti-CTLA-4 antibody as compared to a wild-type extracellular domain of CTLA-4, wherein the anti-CTLA-4 antibody has anti-cancer immunotherapeutic activity.

Abstract: A multi-sensor non-invasive blood glucose monitoring instrument based on impedance spectroscopy-optical method, which belongs to a blood glucose measuring instrument for human body. The blood glucose monitoring instrument comprises a detection probe, a microprocessor, a display unit and a storage unit. The detection probe comprises a temperature and humidity sensor, an LED array, a photoelectric sensor, a pair of low-frequency electrodes, and a pair of high-frequency electrodes. The high-frequency electrode employs parallel electrodes, a matching inductor is directly soldered to the positive electrode or negative electrode of the electrode, and a shielding electrode is provided around the high-frequency electrode. The distance between the two low-frequency electrodes is 1 cm-2 m, and the low-frequency electrodes can test the low-frequency impedance of the tissue stably.

Abstract: A compressed air distributor which is mounted on a spray gun, comprising: a compressed air inlet pipe disposed within a spray gun body, an annular gas supply pipe, an adjustment screw plug, a screw, an adjustment nut, an adjustment knob, a groove, and an adjustment through hole; wherein the center line of the adjustment through hole is eccentrically disposed on the axis line of the adjustment screw plug; wherein the bottom surface of the adjustment screw plug is coupled to an enclosed base having a connecting passage communicating with the annular gas supply pipe; when the adjustment screw plug is rotated, the adjustment through hole can be communicated with the connecting passage or sealed by the enclosed base. The compressed air distributor has a simple structure, low manufacturing cost, and is able to flexibly adjust the size of the spraying flow.

Abstract: A sealing structure of a plunger pump, comprising: a pump body and a plunger rod assembly disposed in the pump body; wherein the pump body includes an upper pump and a lower pump, and the upper pump and lower pump are fixed by screw connection; a sealing ring provided between the upper pump and the lower pump; wherein the plunger rod assembly includes an annular groove disposed at a position adjacent to a lower portion of the plunger rod at an outer peripheral surface thereof; a dynamic lip seal fitted in the annular groove; and a static lip seal sleeved on the outer peripheral surface of the plunger rod; the sealing structure of the plunger pump has good sealing effect, good anti-wear and anti-wear effect, simple replacement and low maintenance cost.

Abstract: A bacterial strain of Actinoplanes sp. and and the use thereof. The bacterial strain is named Actinoplanes sp. HS-16-20, whose preservation number is CGMCC (China General Microbiological Culture Collection Center) No. 7294. The bacterial strain can be used to generate Fidaxomicin or analogs thereof or compositions containing Fidaxomicin, such as by aerobically fermenting the strain in nutrient medium containing assimilable carbon and/or nitrogen sources. Fidaxomicin has an inhibitory effect on various gram positive bacteria pathogens, and in particular, on Clostridium difficile.

Abstract: A unidirectionally bendable transmission chain. At a first side thereof, an inner stop plate is fixed between a pair of inner chain plates at both ends of pin shafts, and an outer stop plate is fixed between a pair of outer chain plates at both ends of the pin shafts. Both ends of the inner stop plate are flush with axes of pin holes provided at both ends of the inner chain plates, and both ends of the outer stop plate are respectively provided with extensions beyond the outer chain plates; the extensions of the outer stop plate form a one-sided support for the inner stop plate to prevent the transmission chain from bending toward the first side, thus the transmission chain bends unidirectionally toward a second side opposite to the first side. A hoisting mechanism and a liftable roadblock having the above transmission chain.

Abstract: This invention relates to a navigation system for integrating a number of positioning receivers to obtain a final position. The navigation system comprises an operation and control module and a unifying module. The operation and control module is being configured to receive a location data from each of the positioning receivers and transmits the location data to the unifying module. The unifying module will then determine the final position based on a statistical model. In particular, the statistical model uses normal distribution to determine the final position. This final position is then displayed on the display of the navigation system.

Abstract: A unidirectionally bendable transmission chain is provided. At a first side thereof, an inner stop plate is fixed between a pair of inner chain plates at both ends of pin shafts, and an outer stop plate is fixed between a pair of outer chain plates at both ends of the pin shafts. Both ends of the inner stop plate are flush with axes of pin holes provided at both ends of the inner chain plates, and both ends of the outer stop plate are respectively provided with extensions beyond the outer chain plates; the extensions of the outer stop plate form a one-sided support for the inner stop plate to prevent the transmission chain from bending toward the first side, thus the transmission chain bends unidirectionally toward a second side opposite to the first side. A hoisting mechanism and a liftable roadblock having the above transmission chain are further provided.

Abstract: This invention relates to a navigation system for integrating a number of positioning receivers to obtain a final position. The navigation system comprises an operation and control module and a unifying module. The operation and control module is being configured to receive a location data from each of the positioning receivers and transmits the location data to the unifying module. The unifying module will then determine the final position based on a statistical model. In particular, the statistical model uses normal distribution to determine the final position. This final position is then displayed on the display of the navigation system.

Abstract: A GaN based LED epitaxial structure and a method for manufacturing the same. The GaN based LED epitaxial structure may include: a substrate; and a GaN based LED epitaxial structure grown on the substrate, wherein the substrate is a substrate containing a photoluminescence fluorescent material. The photoelectric efficiency of the LED epitaxial structure is enhanced and the amount of heat generated from a device is reduced by utilizing a rare earth element doped Re3Al5O12 substrate; since the LED epitaxial structure takes a fluorescence material as a substrate, a direct white light emission may be implemented by such an LED chip manufactured by the epitaxial structure, so as to simplify the manufacturing procedure of the white light LED light source and to reduce production cost. The defect density of the epitaxial structure is reduced by firstly epitaxial growing, patterning the substrate and then laterally growing a GaN based epitaxial structure.

Abstract: A bacterial strain of Actinoplanes sp. and an application thereof. The bacterial strain is named Actinoplanes sp. HS-16-20, whose preservation number is CGMCC No. 7294. The bacterial strain can generate Fidaxomicin, and Fidaxomicin has an inhibitory effect on various gram positive bacteria pathogens, and in particular, on Clostridium difficile.

Abstract: A gate valve has a body, the body having a cavity and a flow passage intersecting the cavity. A seat fabricated from a ceramic and/or hardfacing alloy matrix composite substrate is mounted to the body at the intersection of the flow passage and the cavity. A gate fabricated from a ceramic and/or hardfacing alloy matrix composite substrate is installed at the cavity and has an engaging face that slidingly engages the seat while the gate is being moved between open and closed positions. The engaging faces of the gate and seats are coated with a low-friction material to facilitate sliding. The ceramic and/or hardfacing alloy matrix composite substrate construction of the gate and seats with low friction engaging surfaces enhances the gate valve's bearing stress capacity.

Abstract: A GaN based LED epitaxial structure and a method for manufacturing the same. The GaN based LED epitaxial structure may include: a substrate; and a GaN based LED epitaxial structure grown on the substrate, wherein the substrate is a substrate containing a photoluminescence fluorescent material. The photoelectric efficiency of the LED epitaxial structure is enhanced and the amount of heat generated from a device is reduced by utilizing a rare earth element doped Re3Al5O12 substrate; since the LED epitaxial structure takes a fluorescence material as a substrate, a direct white light emission may be implemented by such an LED chip manufactured by the epitaxial structure, so as to simplify the manufacturing procedure of the white light LED light source and to reduce production cost. The defect density of the epitaxial structure is reduced by firstly epitaxial growing, patterning the substrate and then laterally growing a GaN based epitaxial structure.

Abstract: A wavelength locking method, apparatus, and system are provided. The wavelength locking method includes modulating, by using scrambling signals with a same frequency and different phases, each one of a plurality of optical channel signals respectively; processing, by a combiner, a splitter, and a wavelength locker, the modulated optical signals, so as to acquire photoelectricity detector (PD) signals; performing phase discrimination on the PD signals to acquire wavelength information of the optical channels; determining different shift values corresponding to the different wavelength information; and adjusting wavelengths of the optical channels according to the corresponding shift values.

Abstract: A system and method for demand forecasting is provided. The system includes a computer system and a demand forecasting engine executed by the computer system. The demand forecasting engine permits inventory management and price optimization, with improved prediction accuracy. The system includes a nonlinear time series model which is able to simulate the market trend of a certain product in the past and make a demand forecast for the future. The system provides initial estimates for new products in a new season, and is self-adjusting with limited data points in the beginning of the season. In this way, the system provides solutions for demand forecasting of old and new products. Furthermore, pricing optimization solutions (e.g., Markov decision processed (MDP) based, etc.) can be built on the basis of the demand forecasting solutions. The system is applicable to many marketing-related problems and is particularly reliable for products which follow a certain cycle.

Abstract: Provided are a method, an apparatus, an integrated circuit, and a system for providing data samples in a measurement and control system. The method comprises obtaining one or more data samples; time stamping the one or more data samples using respective local sampling times according to a local time clock; storing time stamped data samples; time stamping at least one stored data sample using a master sampling time calculated based upon the respective local sampling time and a time clock offset between the local time clock and a backup master time clock of a master device; and sending to the master device the at least one stored data sample time stamped using the master sampling time. With the method, the apparatus, the integrated circuit, and the system, a “point-to-point” serial direct hardware connection between the master devices and A/D Converters may be eliminated, and thereby reducing construction cost significantly.

Abstract: A gate valve has a body, the body having a cavity and a flow passage intersecting the cavity. A seat fabricated from a ceramic and/or hardfacing alloy matrix composite substrate is mounted to the body at the intersection of the flow passage and the cavity. A gate fabricated from a ceramic and/or hardfacing alloy matrix composite substrate is installed at the cavity and has an engaging face that slidingly engages the seat while the gate is being moved between open and closed positions. The engaging faces of the gate and seats are coated with a low-friction material to facilitate sliding. The ceramic and/or hardfacing alloy matrix composite substrate construction of the gate and seats with low friction engaging surfaces enhances the gate valve's bearing stress capacity.