Patents by Inventor Feng He

Feng He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for centralized charging of electronic products
    Patent number: 11239675
    Abstract: Disclosed is an apparatus for centralized charging of electronic products, including a base, where charging grooves, charging racks, and a charging stand are provided on the top surface of the base in sequence from front to back; a charging head A is provided in the charging groove; a connecting piece A matching a plug-in type charging head is provided at the lower part of the charging rack; the base is further provided with connecting pieces B matching the plug-in type charging heads; the connecting pieces B are located at one side of the charging stand; and the charging head A, the connecting piece A, and the connecting piece B are electrically connected to an output end of a power adapter provided in the base, respectively.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: February 1, 2022
    Assignee: HUAIYIN INSTITUTE OF TECHNOLOGY
    Inventors: Yuwei Dong, Hongyan Ding, Feng He, Ling Wang, Zhao Zhang, Yingying Guan, Wenjin Zhao, Xin Huang, Yanshun Hou, Haifeng Zhu, Qinqin Liu
  • Bonded article of thin glass on support substrate, preparation method and use thereof
    Patent number: 11225057
    Abstract: A method for making a bonded article, wherein a thin glass substrate is bonded on a support substrate in the absence of any interlayer by an electrostatic adhesion process with the assistance of external pressure, the pressure is applied constantly or stepwise during the adhesion process by use of a tool such as a roll or a wheel or other movable device with curved surface. The bonded article has no defects, e.g. bubbles or inclusions, in the bonded interface, which benefits transportation of the thin glass substrate and its post-processing as well. Such defect-free bonded article is also disclosed. Pressure supported electrostatic adhesion, initiated by electrostatic charges adhesion of a two members, e.g. a substrate member and a support member, is enabled to minimize, prevent and exclude defects, distortion between the adhered surfaces.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 18, 2022
    Assignee: SCHOTT GLASS TECHNOLOGIES (SUZHOU) CO. LTD.
    Inventors: Pengxiang Qian, Chong Wang, Feng He, Yunfei Hou, Rainer Liebald
  • Crystal forms of oxypyridine amide derivative and preparation method therefor
    Patent number: 11225462
    Abstract: The present invention relates to crystal forms of an oxypyridine amide derivative and a preparation method therefor. In particular, the present invention relates to crystal forms A, B, C, D, E and F of a compound represented by formula (I) and a preparation method therefor. The crystal forms of the compound represented by formula (I) as described in the present invention have good crystal form stability and may be better for clinical use.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: January 18, 2022
    Assignees: JIANGSU HENGRUI MEDICINE CO., LTD., SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
    Inventors: Yahui Ma, Haoyu Zhang, Long Han, Qiyun Shao, Zhenxing Du, Jie Wang, Jun Feng, Feng He
  • FLEXIBLE GLASS ELEMENT AND METHOD FOR PRODUCING THE SAME
    Publication number: 20220002185
    Abstract: An element of an inorganic brittle material having two opposed sides and a circumferential edge includes at least three sections. The at least three sections include a first section and two second sections, the second sections adjoining the first section so that the first section is arranged between the second sections. The first section includes an arrangement of openings forming passages from one side to an opposed side of the element so that the first section has a higher flexibility than the second sections.
    Type: Application
    Filed: July 6, 2021
    Publication date: January 6, 2022
    Applicant: Schott AG
    Inventors: Andreas Ortner, Julia Weißhuhn, Fabian Wagner, Markus Heiß-Chouquet, Volker Seibert, Feng He, Vanessa Gläßer, Ning Da, Wei Xiao
  • SESQUITERPENE SYNTHASES FOR PRODUCTION OF DRIMENOL AND MIXTURES THEREOF
    Publication number: 20210395786
    Abstract: The present application relates to a method of producing drimenol and/or drimenol derivatives by comprising contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also provided are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.
    Type: Application
    Filed: August 20, 2021
    Publication date: December 23, 2021
    Inventors: Pan Li, Qi Wang, Xiu-Feng He, Olivier Haefliger
  • LETTUCE EXTRACT
    Publication number: 20210386103
    Abstract: Described herein are an extract from lettuce (Lactuca sativa), in particular of stalk lettuce (Lactuca sativa var. angustana), including 2-acetyl-1-pyrroline and, optionally, precursors of 2-acetyl-1-pyrroline as well as flavoring compositions including such an extract and a method for the preparation of such an extract. Also described herein are the use of such an extract as a taste or flavor ingredient in a consumer product and a method of enhancing, improving, modifying the taste or flavor of a consumer product by making use of such an extract.
    Type: Application
    Filed: April 23, 2020
    Publication date: December 16, 2021
    Inventors: Xiu-Feng He, Christian Starkenmann, Christoph Cerny, Yi-Min Wang
  • PYRAZOLO-HETEROARYL DERIVATIVE, PREPARATION METHOD AND MEDICAL USE THEREOF
    Publication number: 20210380593
    Abstract: Disclosed are a pyrazolo-heteroaryl derivative, a preparation method and medical use thereof. In particular, this invention relates to a new pyrazolo-heteroaryl derivative as shown in the general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative and the use thereof as a therapeutic agent, in particular as a TLR7 agonist, wherein each substituent in the general formula (I) is defined in the description.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 9, 2021
    Inventors: Guobao ZHANG, Chunfeng SHU, Qiyue HU, Feng HE, Weikang TAO
  • Salt of phenylpropionamide derivative and preparation method therefor
    Patent number: 11180530
    Abstract: A salt of a phenylpropionamide derivative and a preparation method therefor is described. Specifically, the salt of the compound of formula (I) has good stability, and can be better used in clinical treatment. The process for preparing the salt of the compound of formula (I) of the present invention is simple and easy to operate.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: November 23, 2021
    Assignees: Jiangsu Hengrui Medicine CO., LTD., Shanghai Hengrui Pharmaceutical CO., LTD
    Inventors: Lin Wang, Jingquan Ye, Qiyun Shao, Jun Feng, Feng He, Xiaoli Cao, Yahui Ma
  • LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20210353764
    Abstract: The present invention relates to a ligand-drug conjugate of an exatecan analogue, a preparation method therefor and an application thereof. Specifically, the present invention provides a ligand-drug conjugate having a structure shown in formula (-D), a preparation method therefor, a pharmaceutical composition containing same, and use thereof in preparation of drugs for treating cancers by means of receptor regulation. The definition of each substituent in formula (-D) is the same as that in the description.
    Type: Application
    Filed: September 25, 2019
    Publication date: November 18, 2021
    Inventors: Jianyan XU, Ying ZHANG, Xiaofeng CAI, Bolei QU, Jindong LIANG, Lianshan ZHANG, Feng HE, Weikang TAO
  • FUSED TRICYCLIC HETEROCYCLE COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20210300944
    Abstract: This application discloses a new class of fused tricyclic heterocycles of formula (I), preparation methods thereof, pharmaceutical compositions comprising these compounds, and pharmaceutically acceptable salts, solvates, or prodrugs thereof, and their uses for the treatment of diseases in which modulation of STING is beneficial, for example, cancers, pre-cancerous disorders, and viral infections.
    Type: Application
    Filed: June 28, 2019
    Publication date: September 30, 2021
    Inventors: Dong Liu, Lei Chen, Linghang Zhuang, Puhui Li, Xinzhu Zhang, Chunying Song, Matthew Miller, Qiyue Hu, Yuna Yan, Feng He, Weikang Tao
  • METHOD FOR PREPARING COAGULATION FACTOR XIA INHIBITOR AND INTERMEDIATE THEREOF
    Publication number: 20210292279
    Abstract: The present disclosure involves a method for preparing a coagulation factor XIa inhibitor and an intermediate thereof. Specifically, the present disclosure involves a method for preparing an oxypyridine amide derivative. The method has the advantages of high yield, good product purity, and mild reaction conditions.
    Type: Application
    Filed: July 18, 2019
    Publication date: September 23, 2021
    Inventors: Zhuoxun XI, Yingqiang FENG, Jun FENG, Feng HE, Jian HUANG, Yanli MAO, Yong WANG, Zhongjun GUAN
  • Sesquiterpene synthases for production of drimenol and mixtures thereof
    Patent number: 11124807
    Abstract: Described herein is a method of producing drimenol and/or drimenol derivatives, the method including contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. Also described herein are host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: September 21, 2021
    Assignee: Firmenich SA
    Inventors: Pan Li, Qi Wang, Xiu-Feng He, Olivier Haefliger
  • Pyrazolo-heteroaryl derivative, preparation method and medical use thereof
    Patent number: 11117898
    Abstract: Disclosed are a pyrazolo-heteroaryl derivative, a preparation method and medical use thereof. In particular, this invention relates to a new pyrazolo-heteroaryl derivative as shown in the general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative and the use thereof as a therapeutic agent, in particular as a TLR7 agonist, wherein each substituent in the general formula (I) is defined in the description.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: September 14, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Guobao Zhang, Chunfeng Shu, Qiyue Hu, Feng He, Weikang Tao
  • Heteroaryl-pyrazole derivative, and preparation method therefor and medical application thereof
    Patent number: 11111249
    Abstract: A heteroaryl-pyrazole derivative, and a preparation method therefor and a medical application thereof are described. Specifically, a new heteroaryl-pyrazole derivative as shown in formula (I), a preparation method for the derivative, a pharmaceutical composition containing the derivative, and a use of the derivative as a therapeutic agent, in particular as a TLR7 agonist, are described. The substituents in formula (I) have the same definitions as in the description.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: September 7, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Guobao Zhang, Dianqiang Ma, Huiqing Yuan, Feng He, Weikang Tao
  • PYRIDOPYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
    Publication number: 20210269439
    Abstract: Disclosed are a pyridopyrimidine derivative as shown in general formula (I), a preparation method therefor and a pharmaceutical composition containing the derivative, and the use thereof as a therapeutic agent, particularly as a TLR8 agonist, wherein each substituent of general formula (I) is the same as those defined in the description.
    Type: Application
    Filed: July 2, 2019
    Publication date: September 2, 2021
    Inventors: Guobao Zhang, Yiqian Chen, Feng He, Weikang Tao
  • CD73 INHIBITORS AND THERAPEUTIC USES THEREOF
    Publication number: 20210253621
    Abstract: This application discloses CD73 inhibitors represented by the general formula (I) and analogs thereof, pharmaceutical compositions containing these compounds, methods of preparing them, and use of these compounds as therapeutic agents for the treatment of diseases or conditions associated with CD73 activity, such as various cancers.
    Type: Application
    Filed: August 28, 2019
    Publication date: August 19, 2021
    Inventors: Jian Liu, Heping Wu, Linghang Zhuang, Suxing Liu, Rumin Zhang, Feng He, Weikang Tao
  • METHOD FOR PRODUCING ALBICANOL COMPOUNDS
    Publication number: 20210254039
    Abstract: Described herein is a method of producing a drimane sesquiterpene, such as an albicanol compound and/or derivatives thereof, by contacting at least one polypeptide with farnesyl diphosphate (FPP) with a polypeptide of the Haloacid dehalogenase-like (HAD-like) hydrolase superfamily as obtainable from plants of the genus Dryopteris, in particular of the species Dryopteris fragrans. The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. Also described herein are host cells or organisms genetically modified to express the polypeptides and useful to produce a drimane sesquiterpene such as an albicanol compound.
    Type: Application
    Filed: May 28, 2019
    Publication date: August 19, 2021
    Inventors: Didier Belorgey, Xiu-Feng He, Qi Wang, Lily Ji-Xiu Zhang
  • Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof
    Patent number: 11084808
    Abstract: The present invention relates to an oxopicolinamide derivative, a preparation method therefor and the pharmaceutical use thereof. In particular, the present invention relates to an oxopicolinamide derivative as shown in the general formula (AI), a preparation method therefor and a pharmaceutical composition comprising the derivative, and to the use thereof as a therapeutic agent, in particular as an inhibitor of blood coagulation factor XIa (Factor XIa, FXIa for short) and the use thereof in the preparation of a drug for treating diseases such as thromboembolism, wherein the definition of each substituent in the general formula (AI) is the same as defined in the description.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: August 10, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Fanglong Yang, Weimin Wang, Xiaodong Li, Gang Chen, Feng He, Weikang Tao
  • 1,2,4-TRIAZINE-3-AMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE
    Publication number: 20210230138
    Abstract: A 1,2,4-triazine-3-amine derivative, a preparation therefor, and use thereof in medicine are provided. Specifically, a 1,2,4-triazine-3-amine derivative as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and use thereof as a therapeutic agent, in particular as an A2a or A2b receptor antagonist, and use thereof in the preparation of a medicament for treating a condition or disorder that is ameliorated by means of inhibition of the A2a or A2b receptor are provided. Each substituent in general formula (I) is defined in the description.
    Type: Application
    Filed: April 6, 2021
    Publication date: July 29, 2021
    Inventors: Biao LU, Junzhen ZHANG, Fangfang JIN, Feng HE, Weikang TAO
  • Magazine bracket
    Patent number: D940812
    Type: Grant
    Filed: January 18, 2021
    Date of Patent: January 11, 2022
    Inventor: Feng He