Abstract: Provided herein is a class of ionizable lipid compounds represented by formula ((IV?), or pharmaceutically acceptable salts, isotopic variants, tautomers or stereoisomers thereof. Also provided is a nanoparticle pharmaceutical composition comprising said compound, and the application of said compound and its composition in the delivery of nucleic acids.

Abstract: A cobalt-free positive electrode material, a preparation method therefor, and an application thereof. The preparation method comprises: mixing a lithium source, a cobalt-free precursor NixMny(OH)2, a nickel source, and a manganese source, performing primary sintering and secondary coating and sintering, and obtaining a cobalt-free positive electrode material, wherein the nickel source comprises nickel oxide, the manganese source comprises at least one among manganese dioxide, manganese(II,III) oxide, and manganese(II) oxide, and the molar ratio of the nickel source to the manganese source is x/y.

Abstract: Provided in the present disclosure are a fluorine-doped lithium positive electrode material, a preparation method therefore and the use thereof. The preparation method includes: step S1, mixing and reacting NH4F, LixNiyMnzO2 and water to obtain an intermediate product system, which includes fluorine-modified LixNiyMnzO2; and step S2, carrying out first calcination on the fluorine-modified LixNiyMnzO2 in a first oxygen-containing gas, so as to obtain a fluorine-doped lithium positive electrode material, wherein x=1 to 1.3, y=0.1 to 0.9, z=0.1 to 0.9, and x:(y+z)=1.4 to 1.6. Doping with fluorine in a positive electrode material results in the oxygen in the material being protected by fluorine, such that the primary efficiency of a lithium-ion battery is effectively improved.

Abstract: A composition including 2,4-dihydroxybenzoic acid and a positive allosteric modulator, a sweetened composition including at least one sweetener and a taste modifier composition including 2,4-dihydroxybenzoic acid and a positive allosteric modulator, and a method of modifying the taste of a sweetened composition by adding to the sweetened composition a taste modifier composition including 2,4-dihydroxybenzoic acid and a positive allosteric modulator.

Abstract: Disclosed in the present text are a magnetic shielding structure for wireless charging and a manufacturing method therefor, which belong to the technical field of wireless charging. The magnetic shielding structure comprises: a plurality of nanocrystalline units and a heat conduction unit, wherein the heat conduction unit is arranged between the nanocrystalline units, and is used for connecting the nanocrystalline units and conducting heat; and each nanocrystalline unit comprises a multilayer nanocrystalline material. Provided in the application are a magnetic shielding structure and a manufacturing method therefor, which magnetic shielding structure has a relatively small eddy-current loss, a good heat dissipation performance and insulation performance, high flexibility and reliability, and a small volume and a light weight, and is suitable for high-power wireless charging.

Abstract: The invention provides an electrochemical discharge-assisted micro-grinding device for micro-components of brittle and hard materials. The device includes a micro-grinding tool, grinding fluid, a workpiece, an auxiliary electrode, a processing groove, and a pulsed DC power supply; the processing groove is filled with grinding fluid; the micro-grinding tool, the workpiece, and the auxiliary electrode are immersed in the grinding fluid; the micro-grinding tool is composed of a conductive grinding tool base, an electroplating layer, and insulated superabrasives. The micro-grinding tool is connected to the negative electrode of the pulsed DC power supply; the grinding fluid is composed of H2O2, Na2CO3, EDTA-Fe-Na, and deionized water; the workpiece material is brittle and hard; a large number of micro structures need to be produced on the surface of the workpiece.

Abstract: A wireless repeater is in communication with a wireless communication device and a wireless access point (AP) and includes a packet transceiver circuit and a computing circuit. The computing circuit is configured to control the packet transceiver circuit to receive from the wireless communication device or the wireless access point a first frame that includes a first receiver address, a first transmitter address, a first destination address, and a first source address, and to control the packet transceiver circuit to send a second frame to the wireless AP or the wireless communication device, the second frame including a second receiver address, a second transmitter address, a second destination address, and a second source address. The first source address is identical to the second source address, the first destination address is identical to the second destination address, and the first receiver address is identical to the second transmitter address.

Abstract: A consumable is provided. The consumable includes (a) at least one sweetener, and (b) a sweetness modifier comprising an extract or fraction from Gnaphalium affine or at least one flavonoid compound. The at least one sweetener is present is a sweetening amount.

Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.

Abstract: The disclosure provides at compounds of Formula I, compositions comprising the same, and methods of using the same, including use in treating diseases, disorders of conditions mediated by the signaling of formyl peptide receptor 1 (FPR1).

Abstract: The present disclosure relates to a thermal coupling method for preparing ethylene by ethanol dehydration and device thereof. The device includes an ethanol dehydration reaction system, a quenching compression system, an alkaline washing system, a molecular sieve drying system and an ethylene purification and propylene refrigeration cycle system; ethanol dehydration reaction products in the ethanol dehydration reaction system serve as a heat source for preheating, vaporization and superheating of a raw material of ethanol; tower bottoms of an evaporation tower in the quenching compression system serve as a heat source for preheating of a feed stream of the evaporation tower and heating of an overhead gas of a quenching tower; products of ethylene in the alkaline washing system serve as a cold source for cooling of crude ethylene.

Abstract: This paper describes an invention involving an electrochemical discharge-enabled micro-grinding process for micro-components of silicon-based materials. The specific machining method is described below. A micro-grinding tool and an auxiliary electrode are respectively connected to the negative and positive electrodes of a pulsed DC power supply. When the current flows through the loop, an electrochemical hydrogen evolution reaction (HER) occurs at the micro-grinding tool in the grinding fluid, which generate multiple hydrogen bubbles. The bubbles coalesce into an insulating gas film and separate the micro-grinding tool from the grinding fluid; when the critical voltage is reached, the gas film is broken down and an electrochemical discharge occurs accompanied by discharge spark; under the action of the discharge spark, the surface material of the workpiece in the discharge-affected region is directly ablated to generate a heat-affected layer (HAL), namely, physical modification.

Abstract: Compounds of Formula I, compositions comprising the same, and methods of using the same, including use in treating diseases, disorders of conditions mediated by the signaling of formyl peptide receptor 1 (FPR1).

Abstract: A consumable is provided. The consumable includes (a) at least one sweetener, and (b) a sweetness modifier comprising an extract or fraction from Viscum articulatum or at least one flavan or flavanone compound. The at least one sweetener is present is a sweetening amount.

Abstract: The present invention relates to a preparation system of ethylene by ethanol dehydration and device thereof. The device includes an ethanol dehydration reaction system, a quenching compression system, an alkaline washing system, a molecular sieve drying system, an ethylene purification system and a propylene refrigeration cycle system. Part of ethylene produced by the ethylene purification system are used as circulating ethylene in the molecular sieve drying system for desorption regeneration of molecular sieve drying towers. The molecular sieve drying system includes the steps: (1) feeding crude ethylene and water from the alkaline washing system into the molecular sieve drying system, and after removing the water therefrom, feeding the obtained crude ethylene into the ethylene purification system; and (2) feeding part of the products of ethylene, as the circulating ethylene, produced by the ethylene purification system into the molecular sieve drying system.

Abstract: A consumable is provided. The consumable includes (a) at least one sweetener, and (b) a sweetness modifier comprising an extract or fraction from Stelmatocrypton khasianum or at least one caffeoylquinic acid or tormentic acid compound. The at least one sweetener is present is a sweetening amount.

Abstract: A flavour composition comprising a compound according to the formula (I) edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and m is 0 or 1.

Abstract: Provided are novel fusion proteins, nucleic acids encoding said proteins, vectors comprising said nucleic acids, compositions comprising said nucleic acids or vectors, host cells comprising said nucleic acids, vectors or compositions or pharmaceutical compositions. Provided are methods of reducing (down regulating) a target membrane-bound protein (MBP) level in a cell, methods of producing a cell having a reduced target membrane-bound protein level, or methods of treating a disease, or methods of reducing or preventing GvHD in a subject associated with the administration of one or more CAR T-cells to the subject.

Abstract: The invention provides an electrochemical discharge-assisted micro-grinding device for micro-components of brittle and hard materials. The device includes a micro-grinding tool, grinding fluid, a workpiece, an auxiliary electrode, a processing groove, and a pulsed DC power supply; the processing groove is filled with grinding fluid; the micro-grinding tool, the workpiece, and the auxiliary electrode are immersed in the grinding fluid; the micro-grinding tool is composed of a conductive grinding tool base, an electroplating layer, and insulated superabrasives. The micro-grinding tool is connected to the negative electrode of the pulsed DC power supply; the grinding fluid is composed of H2O2, Na2CO3, EDTA-Fe-Na, and deionized water; the workpiece material is brittle and hard; a large number of micro structures need to be produced on the surface of the workpiece.