Patents by Inventor Feng Shi

Feng Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230313834
    Abstract: A bearing including: a sidewall including a substrate and a low friction layer overlying the substrate, where the sidewall further includes: an unformed section; at least one slot in the unformed section; and at least one protrusion extending from the unformed section forming a generally concave or convex cross-sectional shape in the sidewall.
    Type: Application
    Filed: March 31, 2023
    Publication date: October 5, 2023
    Inventors: Jian MA, Xiaoye Liu, Timothy J. Hagan, Johanna Merluza, Feng Shi, Michael Adrian Danyluk, Florian Foerster
  • Publication number: 20230302054
    Abstract: Modified immune cells are provided, the modified immune cells expressing a heterologous polynucleotide comprising a nucleotide sequence encoding a function (e.g., at least one of persistence, proliferation, or cytotoxicity) booster, e.g., an apoptosis inhibitor. In one aspect, the modified T cells further comprise a chimeric antigen receptor. Methods, kits, and components for making and using the modified immune cells are also provided.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 28, 2023
    Applicants: DNA Twopointo, The General Hospital Corporation
    Inventors: Yifang Shui, Jeremy Minshull, Maggie Lee, Feng Shi
  • Publication number: 20230294189
    Abstract: This paper describes an invention involving an electrochemical discharge-enabled micro-grinding process for micro-components of silicon-based materials. The specific machining method is described below. A micro-grinding tool and an auxiliary electrode are respectively connected to the negative and positive electrodes of a pulsed DC power supply. When the current flows through the loop, an electrochemical hydrogen evolution reaction (HER) occurs at the micro-grinding tool in the grinding fluid, which generate multiple hydrogen bubbles. The bubbles coalesce into an insulating gas film and separate the micro-grinding tool from the grinding fluid; when the critical voltage is reached, the gas film is broken down and an electrochemical discharge occurs accompanied by discharge spark; under the action of the discharge spark, the surface material of the workpiece in the discharge-affected region is directly ablated to generate a heat-affected layer (HAL), namely, physical modification.
    Type: Application
    Filed: April 29, 2022
    Publication date: September 21, 2023
    Inventors: Cong MAO, Weidong TANG, Yuanqiang LUO, Yinghui REN, Wei LI, Mingjun ZHANG, Kun TANG, Gang WU, Yongle HU, Feng SHI, Ziyang CHEN, Zhuo WEN
  • Patent number: 11739123
    Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: August 29, 2023
    Assignee: OnKure, Inc.
    Inventors: Anthony D. Piscopio, Xiaoyong Fu, Feng Shi, Huayan Liu, Zhifeng Li
  • Publication number: 20230266141
    Abstract: A method for automatically marking a U-turn lane line includes: obtaining information about an intersection entry point, information about an intersection exit point, and information about an obstacle at a to-be-marked intersection; and marking a U-turn lane line with a first depth. The first depth is determined based on a second depth of the obstacle. The first depth of the U-turn lane line is determined based on the second depth of the obstacle, so that a marked U-turn lane line does not collide with the obstacle, to mark a more proper U-turn lane line.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 24, 2023
    Inventors: Dawei Liu, Feng Shi
  • Patent number: 11701870
    Abstract: Provided are a composite material and a preparation method therefor. The composite material comprises: a base layer; a first plant fibre fabric located on the upper surface of the base layer; optionally, a second plant fibre fabric located on the lower surface of the base layer; and resins present in each layer. The composite material has a decorative performance and an improved mechanical performance.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 18, 2023
    Inventors: Xiaosu Yi, Yan Tan, Jianfeng Tong, Qinghua Liao, Xu Chen, Feng Shi, Hu Zhang, Le Luo, Ziqing Liang, Nengwen Liu, Lingsheng Zhong
  • Patent number: 11692186
    Abstract: The present invention provides a snake venom thrombin marker peptide of Agkistrodon Halys Pallas and an application of the snake venom thrombin-like enzyme in identifying species of Hemocoagulase for Injection. The application includes the following steps of: dissolving a to-be-detected sample and a reference substance of the marker peptide respectively to prepare a test solution and a reference solution, and conducting alkylation reduction on the test solution and the reference solution with dithiothreitol and iodoacetamide; after diluting products with an ammonium bicarbonate solution, adding enzyme for hydrolysis; and after enzymolysis is finished, conducting centrifugation at a high speed, and injecting a supernatan into a liquid chromatography-mass spectrometer for analysis. This method is simple, convenient and rapid, is strong in specificity, fills the gap in identifying the source of species of the snake venom thrombin-like enzyme of Agkistrodon Halys Pallas and improves the quality control level.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: July 4, 2023
    Assignees: Shandong University, Shandong Institute for Food and Drug Control, Avanc Pharmaceutical Co., Ltd
    Inventors: Ruiqing Xian, Feng Shi, Liping Gong, Lianli Chi, Qunye Zhang, Weijian Wang, Hongming Du, Congcong Wang, Baojian Hang, Fengshan Wang
  • Publication number: 20230201998
    Abstract: A jet polishing device capable of stably forming a Gaussian removal function includes: an auxiliary mounting mechanism; a jet machining mechanism. The jet machining mechanism is connected with the auxiliary mounting mechanism, the jet machining mechanism includes a rotation driving assembly, a positioning assembly and a jet machining assembly, the positioning assembly includes a linear guide rail, a slide mass, a first laser and a second laser, the rotation driving assembly is connected with the linear guide rail, the slide mass is slidably connected to the linear guide rail, the first laser is fixedly arranged relative to the linear guide rail, the jet machining assembly includes a mounting bracket fixedly connected with the slide mass, a nozzle mounting body rotatably connected to the mounting bracket and a nozzle arranged on the nozzle mounting body, and the second laser is connected with the nozzle mounting body.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 29, 2023
    Inventors: Ci SONG, Guipeng TIE, Zhiqiang ZHANG, Feng SHI, Ye TIAN
  • Patent number: 11680947
    Abstract: Disclosed are specifically a marker polypeptide of a Bothrops atrox-like thrombin and a method thereof for detecting species source and content of a snake venom-like thrombin and an application, relating to the technical field of snake venom detection. An amino acid sequence of the marker polypeptide is EAYNGLPAK (SEQ ID NO:1), and the marker polypeptide may be used to detect the species source and content of the snake venom-like thrombin in a sample. The marker polypeptide of the present disclosure may play an important role in characterizing the species source and content of the snake venom-like thrombin in the sample, and fill in the blank of a quality standard of snake venom of the Bothrops atrox.
    Type: Grant
    Filed: September 15, 2022
    Date of Patent: June 20, 2023
    Assignees: Shandong Institute for Food and Drug Control, Penglai Nuokang Pharmaceutical Co., Ltd.
    Inventors: Feng Shi, Weijian Wang, Ruiqing Xian, Liping Gong, Congcong Wang, Baojian Hang, Jing Dong, Honghai Li
  • Patent number: 11658005
    Abstract: The present disclosure provides a system and method for controlling a dynamically controllable ultrawide-amplitude and high-response ion source, including: resolving dwell time of ion beam machining during iterative machining; selecting an appropriate velocity V of a movable shaft of a machine tool according to a calculation result of the dwell time; and dynamically calculating process parameters of an ion source according to an initial surface error of an optical component and the velocity V of the movable shaft, and generating a corresponding numerical control (NC) program to machine the optical component. The present disclosure can control the removal function of the ion beam polishing in real time, improve the precision and efficiency of the ion beam polishing, and further reduce the requirement on a movement system of the machine tool and the depth of a damaged layer.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: May 23, 2023
    Assignee: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY, PEOPLE'S LIBERATION ARMY OF CHINA
    Inventors: Ye Tian, Feng Shi, Guangqi Zhou, Ci Song, Guipeng Tie, Gang Zhou
  • Publication number: 20230151825
    Abstract: A compressor for an aircraft engine. A rotor includes blades rotatable about an axis. Blade tips extend between leading and trailing edges. A shroud surrounds the rotor, with an inner surface surrounding the tips. Grooves are defined in the shroud inner surface adjacent the tips. The grooves extend circumferentially about the shroud and radially from inlet openings to closed end surfaces. Groove sidewalls extend circumferentially about the axis. The grooves are axially spaced-apart, the most upstream inlet opening having an upstream end disposed upstream of the leading edges of the blades. The grooves have a swept angle from the inner surface, with a center of the inlet openings is axially offset of a center of the closed-end surfaces. The grooves span an overall axial distance corresponding to 30% or more of the blades’ chord length. The grooves have circumferential interruptions defined by baffles, and extend non-continuously around a shroud circumference.
    Type: Application
    Filed: November 17, 2021
    Publication date: May 18, 2023
    Inventors: Feng SHI, Jason NICHOLS, Hong YU
  • Patent number: 11624736
    Abstract: The present application is related to a method for identifying whether porcine heparin is adulterated with heparin from ruminants, comprising: (1) respectively detecting the contents of trisaccharide(4S) and ?UA2S-GlcNAc6S (?IA) in a sample and at least three batches of porcine heparin standards; (2) calculating a ratio of the trisaccharide(4S) to the ?IA as well as a standard deviation (SD) of the ratio in the porcine heparin standards; when the ratio of the trisaccharide(4S) to the ?IA in the sample exceeds a maximum value of the ratio in the porcine heparin standards+3SD, where the sample is considered to be mixed or adulterated with heparin from ruminants; wherein the detection method used is hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) or multiple reaction monitoring (MRM). The method can distinguish porcine heparin from ovine and bovine heparin based on the structural differences, regardless of the production process the heparin has undergone.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: April 11, 2023
    Assignees: Shandong University, Shandong Institute for Food and Drug Control
    Inventors: Lianli Chi, Deling Shi, Bin Zhang, Feng Shi, Mengmeng Li, Baojian Hang
  • Patent number: 11615535
    Abstract: A method for assessing a condition of an organ or tissue of a target object is provided. The method may include: obtaining a target image of the target object; segmenting a target region from the target image, the target region of the target image corresponding to a sub-region of the organ or tissue; determining a morphological characteristic value of the target region in the target image; obtaining a reference standard associated with a sample organ or tissue of a plurality of sample objects, the sample organ or tissue being of a same type as the organ or tissue of the target object; and assessing the condition of the organ or tissue of the target object by comparing the morphological characteristic value of the target region in the target image with the reference standard.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: March 28, 2023
    Assignee: SHANGHAI UNITED IMAGING INTELLIGENCE CO., LTD.
    Inventors: Quan Huo, Feng Shi, Qingfeng Li, Bokai Li, Yiqiang Zhan
  • Publication number: 20230092234
    Abstract: Disclosed are specifically a marker polypeptide of a Bothrops atrox-like thrombin and a method thereof for detecting species source and content of a snake venom-like thrombin and an application, relating to the technical field of snake venom detection. An amino acid sequence of the marker polypeptide is EAYNGLPAK (SEQ ID NO:1), and the marker polypeptide may be used to detect the species source and content of the snake venom-like thrombin in a sample. The marker polypeptide of the present disclosure may play an important role in characterizing the species source and content of the snake venom-like thrombin in the sample, and fill in the blank of a quality standard of snake venom of the Bothrops atrox.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 23, 2023
    Applicants: Shandong Institute for Food and Drug Control, Penglai Nuokang Pharmaceutical Co., Ltd.
    Inventors: Feng Shi, Weijian Wang, Ruiqing Xian, Liping Gong, Congcong Wang, Baojian Hang, Jing Dong, Honghai Li
  • Publication number: 20230075532
    Abstract: The present disclosure discloses a method for making an ice surface of an ice rink and an ice rink including the ice surface. In the method, a salt solution is applied to an ice surface. The salt solution contains anions. A concentration of the anions is in a range from about 0.63 mmol/L to about 10 mmol/L. The anions in the salt solution are selected from the group consisting of chloride ions, nitrate ions, bromide ions, iodide ions, chlorate ions, perchlorate ions, thiocyanate ions, and any combination thereof. The ice surface is maintained at a temperature of about ?4° C. to about 14° C. to naturally freeze the salt solution.
    Type: Application
    Filed: March 4, 2022
    Publication date: March 9, 2023
    Inventors: LI-RAN MA, CHANG DONG, YUAN LIU, ZHI-FENG SHI, ZHI-TAO HUANG, HAO-YU WANG, JIA-DAO WANG
  • Patent number: 11584948
    Abstract: The present invention relates to the technical field of chemical analysis and quantitative detection, in particular to a quantitative detection method for snake venom thrombin-like enzyme (SVTLE) from Agkistrodon halys pallas. The quantitative detection method for the SVTLE includes the following steps of taking a reference substance of marker peptide for the SVTLE from Agkistrodon halys pallas with an amino acid sequence of LDSPVSNSAHIAPLSLPSSAPSVGSVCR, and preparing a series of reference solutions with different concentrations; adding the reference solutions in test solutions respectively for enzymolysis, and then taking a supernatant after enzymolysis as a series of solutions to be detected; and adding the solutions to be detected in a liquid chromatogram-mass spectrometer, and then selecting a qualitative ion pair and a quantitative ion pair to detect contents of marker peptide in the solutions to be detected.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: February 21, 2023
    Assignees: Shandong Institute for Food and Drug Control, Shandong University, Avanc Pharmaceutical Co., Ltd
    Inventors: Feng Shi, Liping Gong, Ruiqing Xian, Lianli Chi, Weijian Wang, Baojian Hang, Congcong Wang, Pengfei You, Hongming Du
  • Publication number: 20230024978
    Abstract: A method of providing improved mouthfeel in consumables having a fat content of about 20% or less is provided. The method includes the step of adding to a consumable composition base from about 0.02 parts per billion to about 25 parts per million based on the total weight of the consumable composition of an Amadori compound, without any subsequent heating. The Amadori compound is a reaction product of glucose with proline.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 26, 2023
    Inventors: Feng SHI, Yosuke ONUMA, Yili WANG, Uwe KOHRS
  • Patent number: 11559071
    Abstract: The use of a compound according to formula (I) or the edible salts thereof in an edible composition to mask or modulate an undesired taste or off-taste contained in the edible composition wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: January 24, 2023
    Assignee: GIVAUDAN SA
    Inventors: Feng Shi, Harry Renes, Esther Van Ommeren, Susanna Magdalena Vorster, Yili Wang, Adri De Klerk, Jenifer Augelli
  • Patent number: 11524933
    Abstract: A flavour composition comprising a compound according to the formula (I) or edible salts thereof, wherein R1 is alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl to which it is attached is a residue carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: December 13, 2022
    Assignee: Givaudan SA
    Inventors: Feng Shi, Harry Renes, Esther Van Ommeren, Susanna Magdalena Vorster, Yili Wang, Adri De Klerk, Xiaogen Yang
  • Patent number: D997731
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: September 5, 2023
    Assignee: The Coca-Cola Company
    Inventors: Jeffrey Alan Klok, Eric Robine, Feng Shi