Patents by Inventor Feng Shi

Feng Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230405543
    Abstract: The present invention relates to a preparation system of ethylene by ethanol dehydration and device thereof. The device includes an ethanol dehydration reaction system, a quenching compression system, an alkaline washing system, a molecular sieve drying system, an ethylene purification system and a propylene refrigeration cycle system. Part of ethylene produced by the ethylene purification system are used as circulating ethylene in the molecular sieve drying system for desorption regeneration of molecular sieve drying towers. The molecular sieve drying system includes the steps: (1) feeding crude ethylene and water from the alkaline washing system into the molecular sieve drying system, and after removing the water therefrom, feeding the obtained crude ethylene into the ethylene purification system; and (2) feeding part of the products of ethylene, as the circulating ethylene, produced by the ethylene purification system into the molecular sieve drying system.
    Type: Application
    Filed: June 8, 2023
    Publication date: December 21, 2023
    Inventors: Minhua ZHANG, Hao GONG, He DONG, Feng SHI, Yingzhe YU
  • Publication number: 20230389588
    Abstract: A consumable is provided. The consumable includes (a) at least one sweetener, and (b) a sweetness modifier comprising an extract or fraction from Stelmatocrypton khasianum or at least one caffeoylquinic acid or tormentic acid compound. The at least one sweetener is present is a sweetening amount.
    Type: Application
    Filed: December 15, 2021
    Publication date: December 7, 2023
    Inventors: Feng SHI, Moises GALANO, Laura H LUCAS, Yosuke ONUMA, Matthew Steven ROACH, loana Maria UNGUREANU, Wei YUAN
  • Patent number: 11832638
    Abstract: A flavour composition comprising a compound according to the formula (I) edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and m is 0 or 1.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: December 5, 2023
    Assignee: GIVAUDAN SA
    Inventors: Feng Shi, Harry Renes, Esther Van Ommeren, Susanna Magdalena Vorster, Yili Wang, Adri De Klerk, Chris Winkel
  • Publication number: 20230355764
    Abstract: Provided are novel fusion proteins, nucleic acids encoding said proteins, vectors comprising said nucleic acids, compositions comprising said nucleic acids or vectors, host cells comprising said nucleic acids, vectors or compositions or pharmaceutical compositions. Provided are methods of reducing (down regulating) a target membrane-bound protein (MBP) level in a cell, methods of producing a cell having a reduced target membrane-bound protein level, or methods of treating a disease, or methods of reducing or preventing GvHD in a subject associated with the administration of one or more CAR T-cells to the subject.
    Type: Application
    Filed: September 13, 2021
    Publication date: November 9, 2023
    Inventors: Li Zhou, Feng Shi, Michael Harris
  • Publication number: 20230321740
    Abstract: The invention provides an electrochemical discharge-assisted micro-grinding device for micro-components of brittle and hard materials. The device includes a micro-grinding tool, grinding fluid, a workpiece, an auxiliary electrode, a processing groove, and a pulsed DC power supply; the processing groove is filled with grinding fluid; the micro-grinding tool, the workpiece, and the auxiliary electrode are immersed in the grinding fluid; the micro-grinding tool is composed of a conductive grinding tool base, an electroplating layer, and insulated superabrasives. The micro-grinding tool is connected to the negative electrode of the pulsed DC power supply; the grinding fluid is composed of H2O2, Na2CO3, EDTA-Fe-Na, and deionized water; the workpiece material is brittle and hard; a large number of micro structures need to be produced on the surface of the workpiece.
    Type: Application
    Filed: April 29, 2022
    Publication date: October 12, 2023
    Inventors: Cong MAO, Ziyang CHEN, Yinghui REN, Wei LI, Yuanqiang LUO, Gang WU, Mingjun ZHANG, Kun TANG, Yongle HU, Feng SHI, Weidong TANG, Ci SONG
  • Publication number: 20230313834
    Abstract: A bearing including: a sidewall including a substrate and a low friction layer overlying the substrate, where the sidewall further includes: an unformed section; at least one slot in the unformed section; and at least one protrusion extending from the unformed section forming a generally concave or convex cross-sectional shape in the sidewall.
    Type: Application
    Filed: March 31, 2023
    Publication date: October 5, 2023
    Inventors: Jian MA, Xiaoye Liu, Timothy J. Hagan, Johanna Merluza, Feng Shi, Michael Adrian Danyluk, Florian Foerster
  • Publication number: 20230302054
    Abstract: Modified immune cells are provided, the modified immune cells expressing a heterologous polynucleotide comprising a nucleotide sequence encoding a function (e.g., at least one of persistence, proliferation, or cytotoxicity) booster, e.g., an apoptosis inhibitor. In one aspect, the modified T cells further comprise a chimeric antigen receptor. Methods, kits, and components for making and using the modified immune cells are also provided.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 28, 2023
    Applicants: DNA Twopointo, The General Hospital Corporation
    Inventors: Yifang Shui, Jeremy Minshull, Maggie Lee, Feng Shi
  • Publication number: 20230294189
    Abstract: This paper describes an invention involving an electrochemical discharge-enabled micro-grinding process for micro-components of silicon-based materials. The specific machining method is described below. A micro-grinding tool and an auxiliary electrode are respectively connected to the negative and positive electrodes of a pulsed DC power supply. When the current flows through the loop, an electrochemical hydrogen evolution reaction (HER) occurs at the micro-grinding tool in the grinding fluid, which generate multiple hydrogen bubbles. The bubbles coalesce into an insulating gas film and separate the micro-grinding tool from the grinding fluid; when the critical voltage is reached, the gas film is broken down and an electrochemical discharge occurs accompanied by discharge spark; under the action of the discharge spark, the surface material of the workpiece in the discharge-affected region is directly ablated to generate a heat-affected layer (HAL), namely, physical modification.
    Type: Application
    Filed: April 29, 2022
    Publication date: September 21, 2023
    Inventors: Cong MAO, Weidong TANG, Yuanqiang LUO, Yinghui REN, Wei LI, Mingjun ZHANG, Kun TANG, Gang WU, Yongle HU, Feng SHI, Ziyang CHEN, Zhuo WEN
  • Patent number: 11739123
    Abstract: Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: August 29, 2023
    Assignee: OnKure, Inc.
    Inventors: Anthony D. Piscopio, Xiaoyong Fu, Feng Shi, Huayan Liu, Zhifeng Li
  • Publication number: 20230266141
    Abstract: A method for automatically marking a U-turn lane line includes: obtaining information about an intersection entry point, information about an intersection exit point, and information about an obstacle at a to-be-marked intersection; and marking a U-turn lane line with a first depth. The first depth is determined based on a second depth of the obstacle. The first depth of the U-turn lane line is determined based on the second depth of the obstacle, so that a marked U-turn lane line does not collide with the obstacle, to mark a more proper U-turn lane line.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 24, 2023
    Inventors: Dawei Liu, Feng Shi
  • Patent number: 11701870
    Abstract: Provided are a composite material and a preparation method therefor. The composite material comprises: a base layer; a first plant fibre fabric located on the upper surface of the base layer; optionally, a second plant fibre fabric located on the lower surface of the base layer; and resins present in each layer. The composite material has a decorative performance and an improved mechanical performance.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 18, 2023
    Inventors: Xiaosu Yi, Yan Tan, Jianfeng Tong, Qinghua Liao, Xu Chen, Feng Shi, Hu Zhang, Le Luo, Ziqing Liang, Nengwen Liu, Lingsheng Zhong
  • Patent number: 11692186
    Abstract: The present invention provides a snake venom thrombin marker peptide of Agkistrodon Halys Pallas and an application of the snake venom thrombin-like enzyme in identifying species of Hemocoagulase for Injection. The application includes the following steps of: dissolving a to-be-detected sample and a reference substance of the marker peptide respectively to prepare a test solution and a reference solution, and conducting alkylation reduction on the test solution and the reference solution with dithiothreitol and iodoacetamide; after diluting products with an ammonium bicarbonate solution, adding enzyme for hydrolysis; and after enzymolysis is finished, conducting centrifugation at a high speed, and injecting a supernatan into a liquid chromatography-mass spectrometer for analysis. This method is simple, convenient and rapid, is strong in specificity, fills the gap in identifying the source of species of the snake venom thrombin-like enzyme of Agkistrodon Halys Pallas and improves the quality control level.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: July 4, 2023
    Assignees: Shandong University, Shandong Institute for Food and Drug Control, Avanc Pharmaceutical Co., Ltd
    Inventors: Ruiqing Xian, Feng Shi, Liping Gong, Lianli Chi, Qunye Zhang, Weijian Wang, Hongming Du, Congcong Wang, Baojian Hang, Fengshan Wang
  • Publication number: 20230201998
    Abstract: A jet polishing device capable of stably forming a Gaussian removal function includes: an auxiliary mounting mechanism; a jet machining mechanism. The jet machining mechanism is connected with the auxiliary mounting mechanism, the jet machining mechanism includes a rotation driving assembly, a positioning assembly and a jet machining assembly, the positioning assembly includes a linear guide rail, a slide mass, a first laser and a second laser, the rotation driving assembly is connected with the linear guide rail, the slide mass is slidably connected to the linear guide rail, the first laser is fixedly arranged relative to the linear guide rail, the jet machining assembly includes a mounting bracket fixedly connected with the slide mass, a nozzle mounting body rotatably connected to the mounting bracket and a nozzle arranged on the nozzle mounting body, and the second laser is connected with the nozzle mounting body.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 29, 2023
    Inventors: Ci SONG, Guipeng TIE, Zhiqiang ZHANG, Feng SHI, Ye TIAN
  • Patent number: 11680947
    Abstract: Disclosed are specifically a marker polypeptide of a Bothrops atrox-like thrombin and a method thereof for detecting species source and content of a snake venom-like thrombin and an application, relating to the technical field of snake venom detection. An amino acid sequence of the marker polypeptide is EAYNGLPAK (SEQ ID NO:1), and the marker polypeptide may be used to detect the species source and content of the snake venom-like thrombin in a sample. The marker polypeptide of the present disclosure may play an important role in characterizing the species source and content of the snake venom-like thrombin in the sample, and fill in the blank of a quality standard of snake venom of the Bothrops atrox.
    Type: Grant
    Filed: September 15, 2022
    Date of Patent: June 20, 2023
    Assignees: Shandong Institute for Food and Drug Control, Penglai Nuokang Pharmaceutical Co., Ltd.
    Inventors: Feng Shi, Weijian Wang, Ruiqing Xian, Liping Gong, Congcong Wang, Baojian Hang, Jing Dong, Honghai Li
  • Patent number: 11658005
    Abstract: The present disclosure provides a system and method for controlling a dynamically controllable ultrawide-amplitude and high-response ion source, including: resolving dwell time of ion beam machining during iterative machining; selecting an appropriate velocity V of a movable shaft of a machine tool according to a calculation result of the dwell time; and dynamically calculating process parameters of an ion source according to an initial surface error of an optical component and the velocity V of the movable shaft, and generating a corresponding numerical control (NC) program to machine the optical component. The present disclosure can control the removal function of the ion beam polishing in real time, improve the precision and efficiency of the ion beam polishing, and further reduce the requirement on a movement system of the machine tool and the depth of a damaged layer.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: May 23, 2023
    Assignee: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY, PEOPLE'S LIBERATION ARMY OF CHINA
    Inventors: Ye Tian, Feng Shi, Guangqi Zhou, Ci Song, Guipeng Tie, Gang Zhou
  • Publication number: 20230151825
    Abstract: A compressor for an aircraft engine. A rotor includes blades rotatable about an axis. Blade tips extend between leading and trailing edges. A shroud surrounds the rotor, with an inner surface surrounding the tips. Grooves are defined in the shroud inner surface adjacent the tips. The grooves extend circumferentially about the shroud and radially from inlet openings to closed end surfaces. Groove sidewalls extend circumferentially about the axis. The grooves are axially spaced-apart, the most upstream inlet opening having an upstream end disposed upstream of the leading edges of the blades. The grooves have a swept angle from the inner surface, with a center of the inlet openings is axially offset of a center of the closed-end surfaces. The grooves span an overall axial distance corresponding to 30% or more of the blades’ chord length. The grooves have circumferential interruptions defined by baffles, and extend non-continuously around a shroud circumference.
    Type: Application
    Filed: November 17, 2021
    Publication date: May 18, 2023
    Inventors: Feng SHI, Jason NICHOLS, Hong YU
  • Patent number: 11624736
    Abstract: The present application is related to a method for identifying whether porcine heparin is adulterated with heparin from ruminants, comprising: (1) respectively detecting the contents of trisaccharide(4S) and ?UA2S-GlcNAc6S (?IA) in a sample and at least three batches of porcine heparin standards; (2) calculating a ratio of the trisaccharide(4S) to the ?IA as well as a standard deviation (SD) of the ratio in the porcine heparin standards; when the ratio of the trisaccharide(4S) to the ?IA in the sample exceeds a maximum value of the ratio in the porcine heparin standards+3SD, where the sample is considered to be mixed or adulterated with heparin from ruminants; wherein the detection method used is hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) or multiple reaction monitoring (MRM). The method can distinguish porcine heparin from ovine and bovine heparin based on the structural differences, regardless of the production process the heparin has undergone.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: April 11, 2023
    Assignees: Shandong University, Shandong Institute for Food and Drug Control
    Inventors: Lianli Chi, Deling Shi, Bin Zhang, Feng Shi, Mengmeng Li, Baojian Hang
  • Patent number: 11615535
    Abstract: A method for assessing a condition of an organ or tissue of a target object is provided. The method may include: obtaining a target image of the target object; segmenting a target region from the target image, the target region of the target image corresponding to a sub-region of the organ or tissue; determining a morphological characteristic value of the target region in the target image; obtaining a reference standard associated with a sample organ or tissue of a plurality of sample objects, the sample organ or tissue being of a same type as the organ or tissue of the target object; and assessing the condition of the organ or tissue of the target object by comparing the morphological characteristic value of the target region in the target image with the reference standard.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: March 28, 2023
    Assignee: SHANGHAI UNITED IMAGING INTELLIGENCE CO., LTD.
    Inventors: Quan Huo, Feng Shi, Qingfeng Li, Bokai Li, Yiqiang Zhan
  • Publication number: 20230092234
    Abstract: Disclosed are specifically a marker polypeptide of a Bothrops atrox-like thrombin and a method thereof for detecting species source and content of a snake venom-like thrombin and an application, relating to the technical field of snake venom detection. An amino acid sequence of the marker polypeptide is EAYNGLPAK (SEQ ID NO:1), and the marker polypeptide may be used to detect the species source and content of the snake venom-like thrombin in a sample. The marker polypeptide of the present disclosure may play an important role in characterizing the species source and content of the snake venom-like thrombin in the sample, and fill in the blank of a quality standard of snake venom of the Bothrops atrox.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 23, 2023
    Applicants: Shandong Institute for Food and Drug Control, Penglai Nuokang Pharmaceutical Co., Ltd.
    Inventors: Feng Shi, Weijian Wang, Ruiqing Xian, Liping Gong, Congcong Wang, Baojian Hang, Jing Dong, Honghai Li
  • Patent number: D997731
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: September 5, 2023
    Assignee: The Coca-Cola Company
    Inventors: Jeffrey Alan Klok, Eric Robine, Feng Shi