Abstract: The present invention relates to a needle including: a needle hub having a needle with a distal tip; a ring for protecting the needle in one of a storage condition or end-of-use condition of the needle assembly; a foldable element for moving the protective ring; a biasing element for urging the foldable element from its folded configuration to an unfolded configuration; a retainer for maintaining the biasing element in an intermediate stressed state at least in the storage condition of the needle assembly; and a deactivating element for releasing said retainer at least at the end of the injection step. The invention also relates to an injection device including such a needle assembly and a container.

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

Abstract: The present invention relates to an injection assistance device including a body with a needle, grasping arrangement and first elastic return arrangement to dampen limited movement of the grasping arrangement, in at least one of the two directions, respectively distal or proximal, during an injection phase, and to maintain the body in its insertion position and the needle at a constant insertion length during the injection step, when the user increases, respectively releases, a distal pressure on the grasping arrangement. The invention also relates to an injection set including an injection device and the assistance device.

Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, the features on the plunger and features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose.

Abstract: The present invention relates to an automatic injection device (1) comprising: a container (2) having a longitudinal axis A and movable between a first position and a second position, in which the needle is inserted, biasing means (8), for moving the container to its second position, retaining means (70, 74, 74b) for maintaining said biasing means in a first stressed state, triggering means (90, 91e) for releasing said retaining means, said retaining means comprising a lever member having a rotatable cylinder part and a radial projection extending therefrom, said radial projection being in a first angular position when said retaining means is in its passive condition, said radial projection being in a second angular position, different from said first angular position, when said retaining means is in its active condition, said rotatable cylinder part being included in a transversal plane of said longitudinal axis A.

Abstract: The present invention relates to an injection device including a container, intended for receiving a product and provided with an injection needle and a housing receiving the container. The container is movable relative to the housing between an initial position, an insertion position, and a final position. A collapsible chamber is defined within the housing outside of the container. The chamber is collapsible with the container in the insertion position. The chamber is at least partially defined by a proximal wall and a seal element, wherein, with the container in the initial position, the proximal wall is spaced proximally from the seal element, wherein, with the container in the insertion position, the proximal wall is caused to engage the seal element, and, wherein, with the proximal wall engaging the seal element, the container is caused to move from the insertion position to the final position.

Abstract: A pre-filled syringe assembly having a tamper evident tip cap is provided for indicating if the contents of the syringe assembly have been compromised. The syringe barrel has an interior chamber which defines a pressure therein and is sealed at the proximal and distal ends by a first and second seal, respectively, to maintain this pressure. The second seal is formed of a deformable material and a tip cap is located about the second seal and distal end of the syringe barrel. This tip cap includes a viewable indicator representing a change in state of the syringe contents. The indicator has a portion positioned in contact with the second seal such that the first distinguishing feature is viewable through a portion of the cap. Tampering of the contents within the interior chamber causes a change in pressure and movement of the indicator indicating tampering of the syringe assembly.

Abstract: An assembly having an adaptor for coupling with a medical container having a septum. The adaptor includes a gripping member for securing the adaptor to the medical container; a pierceable elastomeric piece which, in an inactive state of the adaptor, does not contact the septum outer surface with pressure, and, in an active state of the adaptor, contacts the septum outer surface with pressure; a blister comprising a shell and a removable closing membrane forming a housing receiving the adaptor; a retaining system having a first retaining portion on the adaptor and a second retaining portion on the shell, the first retaining portion adapted, in a locked position of the retaining system, to cooperate with the second retaining portion, when the adaptor is not in the active state; and an unlocking portion adapted to transition the retaining system to an unlocked position, when the adaptor is in the active state.

Abstract: A package for a container including a tubular barrel having open distal and proximal ends, the proximal end being sized and shaped to receive a plunger, and the distal end being sized and shaped to receive an injection needle, the package including a plunger rod for the container, a part of the plunger rod being shaped complementarily to at least a part of the external shape of the tubular barrel, and a tray connectable to the plunger rod, the tray and the plunger rod forming the package when they are connected to each other.

Abstract: The present invention relates to a needle assembly (1) to be used in combination with a storing device (200) comprising a barrel (8) defining a chamber (9) receiving a product (4) and a piston (2), the assembly (1) comprising: —needle-bearing portion (7) in a first material, movable between an exposed and a retracted positions of the needle (5), —engaging means (8a, 10, 11, 18,) for securing said needle-bearing portion (7) to said barrel (8) in the exposed position, characterized in that it comprises: —sealing means (15) in a second material for tightly sealing the distal end (9a) of said chamber (9) to said needle-bearing portion (7), —a breakable portion (7a) located between said engaging means (8a, 10, 11, 18,) and said needle-bearing portion (7), which, when broken, allows independent proximal displacement of said needle-bearing portion (7) relative to said engaging means (8a, 10, 11, 18,) between said exposed and said retracted positions, said first material being more rigid than said second material.

Abstract: The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member (20) for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece (50) having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess (51) with a proximal opening and an outer wall (54) in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum.

Abstract: An adaptor for coupling with a medical container filled with a number N of doses of a product including a gripping member for securing the adaptor to the medical container. The gripping member has at least one needle access port intended to face the outer surface of the septum of the medical container. The adaptor also includes a marking-device coupled to the needle access port, for designating to a user a not yet pierced area of said outer surface, for completing the next of the N successive piercings.

Abstract: An adaptor for coupling with a medical container having a collar closed by a septum including: a tubular body closed at a distal end with a transversal wall from which extends a hollow spike, and at a proximal end by a pierceable elastomeric piece including a cavity having a plurality of circumferentially distributed chambers, each chamber being connected to the hollow spike by a radial channel, the tubular body further receiving an intermediate piece including a plurality of through holes aligned on the chambers, a selecting member having a closure wall provided with one opening, capable of rotating so that the opening is successively aligned with each of the through holes, and a gripping member for securing the adaptor to the medical container. Also, an assembly including the adaptor and a medical container.

Abstract: A piston rod for an injection device, including first and second legs, each leg being foldable on itself and including a proximal region. The piston rod is capable of transitioning from a folded position to an unfolded position, and includes a mechanism for coupling the proximal regions of the legs when the piston rod is in the unfolded position. The invention also relates to a kit which includes the piston rod.

Abstract: The present invention relates to a prefillable drug delivery device having a housing receiving a needle hub which is movable with respect to said needle hub between a retracted position and a protection position. The device also includes a tubular barrel intended to receive a drug that is pre-mountable on said housing so that said needle hub closes its distal end. The device further includes a sealing member actionable once said tubular barrel is pre-assembled on said housing, capable of transitioning from an inactive state where no sealing contact is present between said needle hub and said tubular barrel, to an active state, in which sealing contact is performed. In the active state of said sealing member, said tubular barrel is movable in translation with respect to said needle hub between a proximal position and a distal position, for realizing delivery of the drug.

Abstract: The invention relates to a closing system for a container to be held with a single hand. The closing system includes a cap having a skirt and a transversal wall provided with an access port, and a cover substantially parallel to the cap and with a guiding member intended to be used by a user to manipulate the cover. A hinge allows a planar rotation of the cover regarding the cap from a first position to close the access port to a second position to access the access port.

Abstract: The present invention relates to an automatic injection device (1) comprising: a container (2) having a longitudinal axis A and movable between a first position and a second position, in which the needle is inserted, biasing means (8), for moving the container to its second position, retaining means (70, 74, 74b) for maintaining said biasing means in a first stressed state, triggering means (90, 91e) for releasing said retaining means, said retaining means comprising a lever member having a rotatable cylinder part and a radial projection extending therefrom, said radial projection being in a first angular position when said retaining means is in its passive condition, said radial projection being in a second angular position, different from said first angular position, when said retaining means is in its active condition, said rotatable cylinder part being included in a transversal plane of said longitudinal axis A.

Abstract: The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.