Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, the features on the plunger and the features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose.

Abstract: The present invention relates to a device for automatic injection including a container, a piston and a piston rod coupled to the piston during the injection. A biasing element is provided for causing distal movement of the piston rod with respect to the container, with a housing receiving the container, the piston rod and the biasing element. The device further including a controlling arrangement for producing an audible indicator at the end of injection.

Abstract: The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.

Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, the features on the plunger and features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose.

Abstract: An adaptor for coupling with a medical container having a collar closed by a septum including: a tubular body closed at a distal end with a transversal wall from which extends a hollow spike, and at a proximal end by a pierceable elastomeric piece including a cavity having a plurality of circumferentially distributed chambers, each chamber being connected to the hollow spike by a radial channel, the tubular body further receiving an intermediate piece including a plurality of through holes aligned on the chambers, a selecting member having a closure wall provided with one opening, capable of rotating so that the opening is successively aligned with each of the through holes, and a gripping member for securing the adaptor to the medical container. Also, an assembly including the adaptor and a medical container.

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

Abstract: The present invention pertains to a stackable packaging unit (1) for the packaging of products (100), the said packaging unit (1) comprising at least one encircling wall (2) provided at least with a corner ridge (3) dividing it into at least two retaining panels (2a) Partially folded down towards one another about the said corner ridge (3) so as to hold the said products (100) to be packaged, at least one end of the said corner ridge (3) being connected to the corresponding edges of the said retaining panels (2a) by at least one inclined centring profile. The stackable packaging unit (1) also comprises an intermediate element. The invention also pertains to a packaging comprising at least one such packaging unit (1).

Abstract: The invention relates to a device for injection of a product into an injection site. The device including a needle shield for protection of a needle prior to use of the device; a housing; and a deshielder for removing the needle shield from the device. The deshielder is coupled to the needle shield and mounted on the housing in a separable manner. The deshielder may include tamper evidence features that are activated by the removal of at least one part of said deshielder. At least one part of the deshielder may be configured to be removed from the housing by exerting a force equal or less to 30 N.

Abstract: The present invention relates to a container comprising: a body; a pusher movable with respect to the body between an initial position and an end-of-use position; a locker located on the pusher and forming an abutment so as to be able to abut against the body between the initial position and the end-of-use position, wherein, the abutment abuts against the body to limit distal movement of the pusher relative to the body to a pusher locking position located between the initial position and the end-of-use position; a locking arrangement capable of, temporarily, locking the locker on the pusher so as to define a locker locking position of the locker on the pusher, the locker locking position establishing the position of the abutment relative to the pusher so as to set the pusher locking position; and, an unlocking arrangement designed so that, with triggering, the locking arrangement is released so as to allow the locker to be displaced relative to the pusher and for the pusher to be moved past the pusher locking

Abstract: The present invention relates to a drug delivery device defining a reservoir for containing a product, having a distal end comprising an end-piece defining a channel for the transfer of the product from the reservoir, said drug delivery device comprising means for coupling said end-piece with a connector, said coupling means comprising a collar defined around a portion of the end-piece and extending from the distal end, said coupling means comprising connection means connectable to said collar, said connection means comprising a tubular wall portion having an interface defined thereon for engagement with an internal face of said collar, and a retaining hook having engagement means engageable with at least part of an external face of said collar when said connection means is connected to said collar.

Abstract: The present invention relates to an injection assistance device including a body with a needle, grasping arrangement and first elastic return arrangement to dampen limited movement of the grasping arrangement, in at least one of the two directions, respectively distal or proximal, during an injection phase, and to maintain the body in its insertion position and the needle at a constant insertion length during the injection step, when the user increases, respectively releases, a distal pressure on the grasping arrangement. The invention also relates to an injection set including an injection device and the assistance device.

Abstract: The invention relates to a device (1) for automatic injection of a product into an injection site, said device (1) further comprising a needle (6) and a needle shield (2) for protection of said needle (6) prior to use of said device, and a housing (300) receiving the container (50) and a deshielder (8) for removing said needle shield (2) from said device (1), said deshielder (8) being coupled to said needle shield (2) and being mounted on the housing (300) in a separable manner, for example through breakable or snap-fit means, said deshielder (8) comprising tamper evidence means that are activated by the removal of at least one part of said deshielder (8). Said at least one part of said deshielder (8) can be removed from the housing (300) by exerting a traction force equal or less to 30 N.

Abstract: The present invention relates to an injection assistance device (1) comprising a body (2) with a needle (7), grasping means (4) and first elastic return means (9) to dampen limited movement of said grasping means (4), in at least one of the two directions, respectively distal or proximal, during an injection phase, and to maintain said body (2) in its insertion position and said needle (7) at a constant insertion length during the injection step, when the user increases, respectively releases, a distal pressure on the grasping means (4). The invention also relates to an injection set (100) comprising an injection device (3) and the said assistance device (1).

Abstract: The present invention relates to a needle including: a needle hub having a needle with a distal tip; a ring for protecting the needle in one of a storage condition or end-of-use condition of the needle assembly; a foldable element for moving the protective ring; a biasing element for urging the foldable element from its folded configuration to an unfolded configuration; a retainer for maintaining the biasing element in an intermediate stressed state at least in the storage condition of the needle assembly; and a deactivating element for releasing said retainer at least at the end of the injection step. The invention also relates to an injection device including such a needle assembly and a container.

Abstract: The present invention relates to a prefillable drug delivery device having a housing receiving a needle hub which is movable with respect to said needle hub between a retracted position and a protection position. The device also includes a tubular barrel intended to receive a drug that is pre-mountable on said housing so that said needle hub closes its distal end. The device further includes a sealing member actionable once said tubular barrel is pre-assembled on said housing, capable of transitioning from an inactive state where no sealing contact is present between said needle hub and said tubular barrel, to an active state, in which sealing contact is performed. In the active state of said sealing member, said tubular barrel is movable in translation with respect to said needle hub between a proximal position and a distal position, for realizing delivery of the drug.

Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, features on the plunger and features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose.

Abstract: The invention relates to an autoinjector (1) comprising: a housing (30, 30a, 30b), a container movable within said housing between an initial position and an insertion position, said movement being prevented when the container is in its passive state, and permitted when the container is in its active state, and a safety shield (40) movable with respect to said housing between a first position and a second position, said movement placing the container in its active state, first retaining means (61, 52) for maintaining said container in its passive state, characterized in that it comprises first deactivating means (50, 51), capable of rotating with respect to said first retaining means from a first position, in which said first retaining means maintain said container in its passive state, to a second position, in which said first retaining means allow the passage of said container in its active state, said rotation being caused by movement of said safety shield from its first position to its second position

Abstract: The present invention relates to a package for a container comprising a tubular barrel having open distal and proximal ends, the proximal end being sized and shaped to receive a plunger, and the distal end being sized and shaped to receive an injection needle, said package comprising a plunger rod for said container, a part of said plunger rod being shaped complementarily to at least a part of the external shape of said tubular barrel, and a tray connectable to said plunger rod, said tray and said plunger rod forming said package when they are connected to each other. The invention further relates to a drug delivery device comprising a container and such a package.

Abstract: The invention relates to a piston rod for an injection device, comprising a first and a second legs, each leg being foldable on itself and comprising a proximal region, said piston rod being in one of a folded position and an unfolded position, said piston rod comprising coupling means for coupling the proximal region of the first leg to the proximal region of the second leg when said piston rod is in said unfolded position. The invention also relates to a kit comprising said piston rod.

Abstract: The present invention relates to an injection device including a container, intended for receiving a product and provided with an injection needle and a housing receiving the container. The container is movable relative to the housing between an initial position, an insertion position, and a final position. A collapsible chamber is defined within the housing outside of the container. The chamber is collapsible with the container in the insertion position. The chamber is at least partially defined by a proximal wall and a seal element, wherein, with the container in the initial position, the proximal wall is spaced proximally from the seal element, wherein, with the container in the insertion position, the proximal wall is caused to engage the seal element, and, wherein, with the proximal wall engaging the seal element, the container is caused to move from the insertion position to the final position.