Abstract: The present invention relates to a drug delivery device defining a reservoir for containing a product, having a distal end comprising an end-piece defining a channel for the transfer of the product from the reservoir, said drug delivery device comprising means for coupling said end-piece with a connector, said coupling means comprising a collar defined around a portion of the end-piece and extending from the distal end, said coupling means comprising connection means connectable to said collar, said connection means comprising a tubular wall portion having an interface defined thereon for engagement with an internal face of said collar, and a retaining hook having engagement means engageable with at least part of an external face of said collar when said connection means is connected to said collar.

Abstract: The present invention relates to an injection device (1) comprising: —a container (5) receiving a product, and provided with an injection needle (6), —a housing (9, 11) receiving said container, said container being movable relative to said housing between an initial position, an insertion position, and a final position, —retaining means (12, 15), for maintaining said container in said insertion position, —deactivating means (20), for releasing said retaining means, said device being characterized in that it comprises: —temporizing means (19, 26, 27), for controlling the release of said retaining means until substantially all of the product contained within said container has passed through said injection needle before said container moves to said final position, and —a needle shield (2) coupled with said housing (9, 11) removal of said needle shield being with limited or no rotation of said needle shield. The invention also concerns a kit comprising such a device.

Abstract: According to the invention, first and second locking means (16, 12) are conformed to engage with each other and to permit the locking of an activation means (4) in at least one intermediate position between first and second positions of the activation means (4). The first and second locking means (12, 16) are conformed to be disengaged from each other when the protection member (3) is in a first position, in which a movement of a vessel contained in the device (1) is possible from an initial position to a position for inserting a needle contained in the vessel, and to be engaged with each other when the protection member (3) leaves said first position.

Abstract: The present invention relates to an injection assistance device (1) for an injection device (3) comprising one body (2), one needle (7), and one piston plunger (26), characterized in that it comprises: a hollow sleeve (4) receiving the body (2), coupling arrangement (10) for moving the piston plunger (26) from an end-of-insertion position to an end of injection position the coupling arrangement being maintained in a passive state until the end-of-insertion position, spacer arrangement (8) to maintain the piston plunger (26) and the body (2) in an initial position, disengaging arrangement (22, 14, 15, 16) linked with the spacer arrangement (8), the spacer arrangement (8) and/or disengaging arrangement (22, 14, 15, 16; 25, 31) being arranged in order not to free the distal displacement of the piston plunger (26) before the one of the body (2).

Abstract: A prefilled ready-to-use syringe, including a tubular body having, at its distal end, a tip to take a needle and, at its proximal end, a flange, a piston able to slide inside the tubular body and defining, with the tubular body, an internal working volume at least partially filled with a liquid, a rod for actuating the piston extending beyond the proximal end of the tubular body, characterized in that a rigid cover is attached and fixed in a definitive way to the flange and has a central opening for the free translational passage of the actuating rod, and the said cover forms a stop for the actuating rod in the proximal direction, and a plug is arranged to translate freely in the tubular body between the piston and the proximal end of the body, the plug being resistant to puncturing with a needle.

Abstract: The present invention relates to an injection device (1) comprising: —a container (5) receiving a product, and provided with an injection needle (6), —a housing (9, 11) receiving said container, said container being movable relative to said housing between an initial position, an insertion position, and a final position, —retaining means (12, 15), for maintaining said container in said insertion position, —deactivating means (20), for releasing said retaining means, said device being characterized in that it comprises: —temporizing means (19, 26, 27), for controlling the release of said retaining means until substantially all of the product contained within said container has passed through said injection needle before said container moves to said final position, and —a needle shield (2) coupled with said housing (9, 11) removal of said needle shield being with limited or no rotation of said needle shield. The invention also concerns a kit comprising such a device.

Abstract: The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.

Abstract: The present invention relates to an injection assistance device (1) comprising a body (2) with a needle (7), grasping means (4) and first elastic return means (9) to dampen limited movement of said grasping means (4), in at least one of the two directions, respectively distal or proximal, during an injection phase, and to maintain said body (2) in its insertion position and said needle (7) at a constant insertion length during the injection step, when the user increases, respectively releases, a distal pressure on the grasping means (4). The invention also relates to an injection set (100) comprising an injection device (3) and the said assistance device (1).

Abstract: An assembly for oral administration of a medicinal product to be reconstituted from an active principle in dry or liquid form and from a diluent, A device including a prefilled syringe with said diluent, able by itself to receive a parenteral injection member is provided. A support including a body of elongate form is fastened to the syringe, the support includes a device for fixing to the syringe and, at its distal end a device for preventing the connecting of the needle to the tip of the syringe. A bottle including the active principle and a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe, the transfer system being separate from the support.

Abstract: The present invention relates to a device (1) for automatic injection comprising a container (2), a piston (8) and: a piston rod (9) coupled to said piston (8) during the injection, biasing means (18) for causing distal movement of said piston rod (9) with respect to said container (2), a housing (14; 214) receiving said container (2), said piston rod (9) and said biasing means (18), controlling means (13, 22) for producing an audible indicator at the end of injection, characterized in that: said controlling means comprise one first element (13), flexible or breakable and coupled to said housing (14), or to said piston rod (9), during the injection, and one second element (22), coupled to said piston rod (9), or to said housing (14), during the injection, said first and second elements cooperating with each other at the end of injection under the effect of the said biasing means (18) to produce said audible indicator.

Abstract: The present invention relates to an injection device (1) comprising:—a container (5) receiving a product, and provided with an injection needle (6),—a housing (9, 11) receiving said container, said container being movable relative to said housing between an initial position, an insertion position, and a final position,—retaining means (12, 15), for maintaining said container in said insertion position,—deactivating means (20), for releasing said retaining means, said device being characterized in that it comprises:—temporizing means (19, 26, 27), for controlling the release of said retaining means until substantially all of the product contained within said container has passed through said injection needle before said container moves to said final position, and—a needle shield (2) coupled with said housing (9, 11) removal of said needle shield being with limited or no rotation of said needle shield. The invention also concerns a kit comprising such a device.

Abstract: The present invention relates to a device (1) for automatic injection of a product (3) and a needle (6).

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab radially moveable between a first radial position, in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position and then allow it to return to the first radial position. The pusher or the casing further includes at least one stop between the pusher and casing to delineate the end of a first stroke corresponding to a first dose of medicament, and the beginning of a second stroke corresponding to a second dose of medicament.

Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing the plunger. The plunger (30) has features which divide the dose into discrete intervals. As the plunger is moved during delivery, features on the plunger and features connected to the barrel interact to provide for intermittent stops to the injection process. Other aspects of the device provide-for reduced dead space, safety and selective interconnection with other devices. Thus, the delivery device divides the dose.

Abstract: A pre-filled syringe assembly having a tamper evident tip cap is provided for indicating if the contents of the syringe assembly have been compromised. The syringe barrel has an interior chamber which defines a pressure therein and is sealed at the proximal and distal ends by a first and second seal, respectively, to maintain this pressure. The second seal is formed of a deformable material and a tip cap is located about the second seal and distal end of the syringe barrel. This tip cap includes a viewable indicator representing a change in state of the syringe contents. The indicator has a portion positioned in contact with the second seal such that the first distinguishing feature is viewable through a portion of the cap. Tampering of the contents within the interior chamber causes a change in pressure and movement of the indicator indicating tampering of the syringe assembly.

Abstract: According to the invention, the accessory (1) comprises a body (15) of roughly semi-tubular shape, first means of holding the syringe comprising a distal transverse wall (20) connected to one end of said body (15), and pierced with a hole (22) for the passage of the needle (7) through it, and second means of holding the syringe comprising a bearing zone (61) against which the proximal flange (10) or the lateral lugs that the syringe body (5) comprises is or are intended to bear so as to provide support for the user's fingers; the distance between said distal transverse wall (20) and said bearing zone (61) is such that the adapter (8) connecting the needle (7) to the syringe body (5) is kept bearing against said distal transverse wall (20) when said flange (10) or said lateral lugs are bearing against said bearing zone (61).

Abstract: The present invention relates to a needle assembly (1) to be used in combination with a storing device (200) comprising a barrel (8) defining a chamber (9) receiving a product (4) and a piston (2), the assembly (1) comprising: —needle-bearing portion (7) in a first material, movable between an exposed and a retracted positions of the needle (5), —engaging means (8a, 10, 11, 18,) for securing said needle-bearing portion (7) to said barrel (8) in the exposed position, characterized in that it comprises: —sealing means (15) in a second material for tightly sealing the distal end (9a) of said chamber (9) to said needle-bearing portion (7), —a breakable portion (7a) located between said engaging means (8a, 10, 11, 18,) and said needle-bearing portion (7), which, when broken, allows independent proximal displacement of said needle-bearing portion (7) relative to said engaging means (8a, 10, 11, 18,) between said exposed and said retracted positions, said first material being more rigid than said second material.

Abstract: A process for decontamination by radiation of a product. The process comprises at least one exposing step during which at least a first part of the product is exposed to a first radiation level, and at least a second part of the product is exposed to a second radiation level. The invention also relates to an equipment suitable for such a process.

Abstract: The invention relates to a device (1) for automatic injection of a product into an injection site, said device (1) further comprising a needle (6) and a needle shield (2) for protection of said needle (6) prior to use of said device, and a housing (300) receiving the container (50) and a deshielder (8) for removing said needle shield (2) from said device (1), said deshielder (8) being coupled to said needle shield (2) and being mounted on the housing (300) in a separable manner, for example through breakable or snap-fit means, said deshielder (8) comprising tamper evidence means that are activated by the removal of at least one part of said deshielder (8). Said at least one part of said deshielder (8) can be removed from the housing (300) by exerting a traction force equal or less to 30 N.

Abstract: The invention relates to an autoinjector (1) comprising: a housing (30, 30a, 30b), a container movable within said housing between an initial position and an insertion position, said movement being prevented when the container is in its passive state, and permitted when the container is in its active state, and a safety shield (40) movable with respect to said housing between a first position and a second position, said movement placing the container in its active state, first retaining means (61, 52) for maintaining said container in its passive state, characterized in that it comprises first deactivating means (50, 51), capable of rotating with respect to said first retaining means from a first position, in which said first retaining means maintain said container in its passive state, to a second position, in which said first retaining means allow the passage of said container in its active state, said rotation being caused by movement of said safety shield from its first position to its second position