Patents by Inventor Fumihisa Kitawaki
Fumihisa Kitawaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20080293074Abstract: A sample solution including blood components is processed with a denaturalization reagent comprising a nonionic surface-activating agent and an oxidizing agent to denaturalize a hemoglobin derivative in the sample solution, and thereafter, an immunoassay is performing utilizing an antibody that is specific to a denaturalized site of the hemoglobin derivative to measure the amount of the hemoglobin derivative in the sample. Therefore, when performing assay of hemoglobin derivative, denaturalization of hemoglobin can be performed speedily and reliably while minimizing adverse effects of the denaturalization reagent on immune reaction.Type: ApplicationFiled: April 12, 2006Publication date: November 27, 2008Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.Inventors: Hirotaka Tanaka, Masanori Tanaka, Fumihisa Kitawaki
-
Publication number: 20080292502Abstract: Herein disclosed is a liquid homogenizer which can evenly mix liquids with small space. There is provided a liquid homogenizer for mixing two or more liquids, comprising: a rotator (1) rotatable around a rotation axis; at least two liquid-mixing chambers (6, 10) formed in the rotator, and being different from each other in distance from the rotation axis; and at least two channels (8) through which one of the liquid-mixing chambers is communicated with the other of the liquid-mixing chambers (6, 10), wherein the liquid-mixing chambers (6, 10) include an outer liquid-mixing chamber (10) and an inner liquid-mixing chamber (6) close to the rotation axis in comparison with the outer liquid-mixing chamber, when the rotator (1) is rotating around the rotation axis, the liquids are shifted by a centrifugal force to the outer liquid-mixing chamber from the inner liquid-mixing chamber through the channels (8), and agitated to be mixed by turbulent flows in the outer liquid-mixing chamber.Type: ApplicationFiled: March 24, 2006Publication date: November 27, 2008Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.Inventors: Fumihisa Kitawaki, Hirotaka Tanaka, Kenji Watanabe
-
Publication number: 20080105566Abstract: A sensor capable of measuring a plurality of measuring items quickly and accurately, a measuring device, and a measuring method are provided. The sensor includes a sample-holding unit for holding a sample containing an analyte; a sample-supplying port for supplying the sample to the sample-holding unit; a detecting unit for carrying out an electrochemical measurement, the unit being provided in the sample-holding unit; an optical measuring unit for carrying out an optical measurement, the unit being provided in the sample-holding unit; and a reagent-holding unit for holding a reagent for the optical measurement, the unit being provided in the sample-holding unit; wherein in the flowing direction of the sample supplied from the sample-supplying port in sample-holding unit, the sample-supplying port, the detecting unit, and the reagent-holding unit are positioned in the order recited.Type: ApplicationFiled: April 22, 2005Publication date: May 8, 2008Inventors: Fumihisa Kitawaki, Akihito Kamei, Tatsurou Kawamura
-
Publication number: 20080083619Abstract: According to the biosensor and the blood component analytical method of the present invention, in a biosensor that is made of a single layer or plural layers of a porous material as shown in FIG. 1, having a reagent holding part and utilizing chromatography, a cell shrinkage reagent is carried on at least part of the reagent holding part, or at least part of a chromatographically developed part that is upstream of the reagent holding part. According to the biosensor having the above-mentioned structure and the blood component analytical method, even when whole blood is a sample, a high-accuracy blood component analysis can be performed easily and quickly with less cost.Type: ApplicationFiled: December 5, 2007Publication date: April 10, 2008Applicant: Matsushita Electric Industrial Co. Ltd.Inventors: Mie Takahashi, Masataka Nadaoka, Hirotaka Tanaka, Fumihisa Kitawaki
-
Publication number: 20080085561Abstract: According to the biosensor and the blood component analytical method of the present invention, in a biosensor that is made of a single layer or plural layers of a porous material as shown in FIG. 1, having a reagent holding part and utilizing chromatography, a cell shrinkage reagent is carried on at least part of the reagent holding part, or at least part of a chromatographically developed part that is upstream of the reagent holding part. According to the biosensor having the above-mentioned structure and the blood component analytical method, even when whole blood is a sample, a high-accuracy blood component analysis can be performed easily and quickly with less cost.Type: ApplicationFiled: December 5, 2007Publication date: April 10, 2008Applicant: Matsushita Electric Industrial Co., Ltd.Inventors: Mie Takahashi, Masataka Nadaoka, Hirotaka Tanaka, Fumihisa Kitawaki
-
Publication number: 20070292964Abstract: Herein disclosed is a measuring equipment, comprising: a light source (13); a light receiving unit (14) disposed in spaced relationship with the light source (13); a device (11) disposed between the light source (13) and the light receiving unit (14); the device (11) having a reaction part (12) for accommodating therein a solid phase support (121), a test substance in a specimen, and a test reagent operative to react with any one of the solid phase support (121) and the test substance, the solid phase support (121) having a surface having a specific binding substance fixed thereon, the specific binding substance being specifically reactive with the test substance, in which, the specific binding substance is adapted to have a plurality of concavities and convexities (123) formed on the solid phase support with the test reagent and the test substance introduced into the reaction part (12) and reacted with each other, the light source (13) is operative to produce a light to transmit through the solid phase suppoType: ApplicationFiled: September 8, 2005Publication date: December 20, 2007Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.Inventors: Fumihisa Kitawaki, Hirotaka Tanaka
-
Publication number: 20070172961Abstract: A method capable of stirring a liquid sample and a reagent promptly and easily includes the following steps (A) and (B). In step (A), using a cell including: a liquid sample retaining section having a plurality of particles; and a liquid sample supply inlet, a liquid sample containing an analyte is supplied from the liquid sample supply inlet to the liquid sample retaining section. In step (B), the liquid sample and a specific binding substance capable of specifically binding to the analyte are stirred by the movement of the particles caused by the flow of the liquid sample in the cell resulting from the supply of the liquid sample, to obtain a liquid mixture. The electric charge of at least the surface of the particles and the electric charge of the specific binding substance have the same polarity in the liquid mixture.Type: ApplicationFiled: March 23, 2005Publication date: July 26, 2007Inventors: Akihito Kamei, Fumihisa Kitawaki, Tatsurou Kawamura, Hiroshi Nakayama, Nobuyuki Shigetou
-
Publication number: 20070105170Abstract: The present invention provides an extracorporeal diagnostic used for measurement of a substance to be tested in a specimen. The extracorporeal diagnostic comprises a reagent which specifically binds to the substance to be tested, and a hydrophilic material (a sugar or a sugar derivative). More particularly, the present invention relates to an extracorporeal diagnostic for measuring a substance to be tested in a specimen. The extracorporeal diagnostic comprises 1) a reagent which specifically binds to the substance to be tested and 2) a compound comprising at least one hydroxyl group and at least one aldehyde group or ketone group.Type: ApplicationFiled: August 31, 2006Publication date: May 10, 2007Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.Inventors: Fumihisa KITAWAKI, Masataka NADAOKA, Mie TAKAHASHI, Hirotaka TANAKA, Hiroshi NAKAYAMA
-
Publication number: 20060281132Abstract: In the present invention, there is provided a method for measuring, under an acidic pH condition, a subject substance in a specimen. The method includes: step A for forming a reaction system by mixing the specimen and an antibody against the subject substance in the specimen; and step B for measuring an antigen-antibody reaction in the reaction system, wherein a pH of the reaction system is set to be acidic, and the relationship between a pI of the antibody and the pH of the reaction system is set to be pI>pH. According to the present invention, a measurement accuracy can be enhanced in an immune measurement reaction system basically using an acidic buffer solution, particularly in a region of low concentration for an antigen.Type: ApplicationFiled: September 22, 2004Publication date: December 14, 2006Inventors: Fumihisa Kitawaki, Akihito Kamei, Tatsurou Kawamura
-
Publication number: 20060275921Abstract: A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an inspection target solution is applied or the downstream of the sample application area in the direction of the inspection target solution permeating, in a development layer. In the so-constituted biosensor, a colored component in the inspection target solution can be faded by the bleaching reagent, so that the color in parts other than a reactive area is reduced in consequence, whereby a visual judgment is possible and a more accurate measurement result in which a reading error by a measuring device is extremely suppressed can be obtained.Type: ApplicationFiled: July 24, 2006Publication date: December 7, 2006Applicant: Matsushita Electric Industrial Co., Ltd.Inventors: Mie Takahashi, Masataka Nadaoka, Hirotaka Tanaka, Fumihisa Kitawaki
-
Publication number: 20060240467Abstract: In order to simplify the pretreatment such as collection of an analyte, treatment of the analyte, introduction of the analyte into a measurement system (reaction system) and dilution of the analyte and to improve operability in examinations using large-sized automatic analyzers and POCT devices, the present invention provides an analyte sampling element including a first region capable of quantitatively collecting and temporarily retaining the analyte and a second region on which a dynamic effect is acted from the outside to move the first region.Type: ApplicationFiled: June 22, 2006Publication date: October 26, 2006Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.Inventors: Fumihisa Kitawaki, Tatsurou Kawamura
-
Patent number: 7112451Abstract: A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an inspection target solution is applied or the downstream of the sample application area in the direction of the inspection target solution permeating, in a development layer. In the so-constituted biosensor, a colored component in the inspection target solution can be faded by the bleaching reagent, so that the color in parts other than a reactive area is reduced in consequence, whereby a visual judgment is possible and a more accurate measurement result in which a reading error by a measuring device is extremely suppressed can be obtained.Type: GrantFiled: June 28, 2001Date of Patent: September 26, 2006Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Mie Takahashi, Masataka Nadaoka, Hirotaka Tanaka, Fumihisa Kitawaki
-
Patent number: 7109309Abstract: It is intended to provide an antibody specific to HbA1c, antibody-producing cells capable of supplying the antibody in a stable state in the future, and a method of constructing the antibody-producing cells without any probability factors, and a method which comprises fusing mouse spleen cells, which have been sensitized with an immunogen composed of a compound containing the following structural formula (I) and a binding protein, with a myeloma-origin cell line, obtaining monoclonal antibody-producing cells by cloning, and then purifying and acquiring the monoclonal antibody produced by these cells into the culture supernatantType: GrantFiled: July 13, 2001Date of Patent: September 19, 2006Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Nobuyuki Shigetoh, Hiroshi Nakayama, Keiko Yugawa, Fumihisa Kitawaki
-
Publication number: 20060144802Abstract: Herein discloses is a testing device, comprising therein an inlet port introducing a blood specimen thereinto, a blood separating chamber held in fluid communication with the inlet port through a fluid passageway to receive a blood specimen, and a hemolyzed blood chamber having accommodated therein a hemolyzed blood fluid. The testing device is operative to be rotated around a rotation center and stop from being rotated to have the blood specimen accommodated in the blood separating chamber into blood cells and a blood plasma fluid, and the blood separating chamber is held in fluid communication with the passageway merging area through a fluid passageway to have the blood plasma fluid separated from the blood specimen flowed through the fluid passageway, in such a manner that the hemolyzed blood fluid is mixed and diluted with the blood plasma fluid in the passageway merging area at a predetermined dilution ratio.Type: ApplicationFiled: December 23, 2005Publication date: July 6, 2006Applicant: Matsushita Electric Industrial Co., Ltd.Inventors: Fumihisa Kitawaki, Toshihiko Yoshioka, Hirotaka Tanaka, Hirofumi Sugimoto, Masanori Tanaka
-
Publication number: 20050228242Abstract: A vital data utilization system that stores and utilizes measured vital data, including: a vital data measurement unit 101 that measures the vital data of a subject; a time measurement unit 102 that stores the information on the measurement date and time at which the vital data was measured; a subject information storage unit 103 on which subject information including the vital data and the information on the measurement date and time that are associated with each other are stored; a reference information storage unit 104 on which reference information including the vital data and the information on the measurement date and time are stored; a subject variation pattern generation unit that extracts, from the subject information storage unit, the subject information in a specific period that lasts until the vital data that satisfies a first predetermined condition is measured, in the case of the measured vital data satisfies the first predetermined condition; a reference variation pattern generation unit 116 thType: ApplicationFiled: April 1, 2005Publication date: October 13, 2005Inventors: Tatsurou Kawamura, Nobuyuki Shigetoh, Akihito Kamei, Fumihisa Kitawaki
-
Publication number: 20050014275Abstract: A blood processing method according to the present invention includes Step St1 of preparing a blood specimen sample and a hemolyzing agent, and Step St2 of mixing the blood specimen sample and the hemolyzing agent to prepare a mixture sample. In this case, the hemolyzing agent is a solid reagent for destroying erythrocyte membranes.Type: ApplicationFiled: March 31, 2003Publication date: January 20, 2005Inventors: Fumihisa Kitawaki, Nobuyuki Shigetoh, Tatsurou Kawamura
-
Publication number: 20040191793Abstract: A fluorescence polarization assay is a method for measuring a subject substance, which includes the steps of: (a) preparing a first solid support body on which a binding substance capable of specifically binding to the subject substance is immobilized and a fluorescent labeled substance which is capable of specifically binding to the subject substance and is labeled with a fluorescent dye; (b) bringing the fluorescent labeled substance and the binding substance into contact with the subject substance; and (c) measuring the polarization degree of fluorescent light from the fluorescent labeled substance.Type: ApplicationFiled: December 17, 2003Publication date: September 30, 2004Inventors: Fumihisa Kitawaki, Tatsurou Kawamura
-
Publication number: 20040161774Abstract: In order to simplify the pretreatment such as collection of an analyte, treatment of the analyte, introduction of the analyte into a measurement system (reaction system) and dilution of the analyte and to improve operability in examinations using large-sized automatic analyzers and POCT devices, the present invention provides an analyte sampling element including a first region capable of quantitatively collecting and temporarily retaining the analyte and a second region on which a dynamic effect is acted from the outside to move the first region.Type: ApplicationFiled: October 2, 2003Publication date: August 19, 2004Inventors: Fumihisa Kitawaki, Tatsurou Kawamura
-
Publication number: 20040161857Abstract: As shown in FIG. 1, an immunochromatography test strip 10 of the present embodiment is made of a base material 11 which includes a sample introduction section 12, a labeling section 13 and an immobilization section 14. The base material 11 is made of a material that is capable of being impregnated with a solvent of a sample solution containing a detection target substance. The material allows migration of a solvent of a sample solution by capillary action. The sample introduction section 12 is a region where a sample solution containing a detection target substance is introduced (e.g., dripped). The sample introduction section 12 contains a metal salt supported thereon. The labeling section 13 contains a labeled antibody 15, which is labeled with a labeling substance, in a state such that the labeled antibody 15 can be eluted into the sample solution. The labeled antibody 15 used herein specifically binds to a detection target substance. The immobilization section 14 contains an immobilized antibody 16.Type: ApplicationFiled: December 17, 2003Publication date: August 19, 2004Inventors: Keiko Yugawa, Fumihisa Kitawaki, Tatsurou Kawamura
-
Publication number: 20040029177Abstract: In a biosensor having a developing layer for developing a sample solution, including a reagent part immobilized to a portion of the developing layer and a marked reagent part which is held in a dry state by a portion of the developing layer, and is dissolvable by developing the sample solution, and qualitatively or quantitatively analyzing an analyte in the sample solution by measuring the amount of the marker reagent bound to the reagent immobilization part; wherein plural reagent immobilization parts exist, and the respective reagent immobilization parts have different affinities for the analyte in the sample solution or the marker reagent, whereby a prozone phenomenon can be detected. Further, a biosensor with a high precision of measurement, which has a wider dynamic range for the concentration of the analyte in the sample solution, can be provided.Type: ApplicationFiled: May 9, 2003Publication date: February 12, 2004Inventors: Masataka Nadaoka, Mie Takahashi, Hirotaka Tanaka, Fumihisa Kitawaki