Patents by Inventor G. Anderson

G. Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified alginates for cell encapsulation and cell therapy
    Patent number: 11337930
    Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: May 24, 2022
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Arturo J. Vegas, Minglin Ma, Kaitlin M. Bratlie, Daniel G. Anderson, Robert S. Langer
  • Total contact cast system and methods for safe and easy removal thereof
    Patent number: 11331733
    Abstract: A cast system, which includes: a padding layer configured to be disposed within a cast and support a portion of a patient's limb; a casting material which hardens around the padding layer and form an outer shell of the cast surrounding the patient's limb; and a wire saw configured to be disposed within the cast and extend along a longitudinal axis of the cast. The wire saw has a cutting surface which is at least partly enclosed by a plastic sheath. By enclosing the wire saw cutting surface in a plastic sheath, the saw does not lock up during the cutting operation, cutting is facilitated, allowing for easy and safe removal of the cast by pulling at least one end of the wire saw so as to cut through the outer shell of the cast.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: May 17, 2022
    Assignee: Woundkair Concepts, Inc.
    Inventors: Danny E. Anderson, Kimberly G. Anderson, Thomas E. Serena, Timothy A. Mayhugh, James R. Wilcox, Cameron B. Morton, Stephen C. Morvel, Jr.
  • Anti-inflammatory coatings to improve biocompatibility of neurological implants
    Patent number: 11318231
    Abstract: Neurological implants whose surfaces have been chemically and covalently modified to impart beneficial properties to the neurological implants are described. The neurological implants possess improved biocompatibility compared to a corresponding neurological implant that lacks the chemical modification. Following implantation in a subject, the surface-modified neurological implants induce a lower-foreign body response, compared to a corresponding unmodified product.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: May 3, 2022
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, SEATTLE CHILDREN'S HOSPITAL
    Inventors: Omid Veiseh, Robert S. Langer, Daniel G. Anderson, William Shain, Brian W. Hanak, Samuel R. Browd, Robert F. Hevner
  • MULTI-FUNCTION AIR DATA PROBE HAVING MULTI-HOLE PORTS USED FOR DETERMINING ANGLE OF ATTACK, TOTAL AND STATIC PRESSURE VALUES
    Publication number: 20220120780
    Abstract: A multi-function air data probe comprises a probe stem having an outer surface that extends between a first end and an opposite second end, with the probe stem having a first cross-sectional diameter; and a probe head having an outer surface that extends between a proximal end and a distal end, wherein the proximal end of the probe head is coupled to the first end of the probe stem. The probe head has a second cross-sectional diameter that is larger than the first cross-sectional diameter of the probe stem. A plurality of multi-hole ports is located in the probe head, with the multi-hole ports extending into and through the probe stem. The air data probe is operative to make measurements used to determine one or more of angle of attack values, total pressure values, and static pressure values.
    Type: Application
    Filed: December 27, 2021
    Publication date: April 21, 2022
    Applicant: Honeywell International Inc.
    Inventors: Morris G. Anderson, Grant A. Gordon
  • EMBOSSING PATTERN WITH A CONTINUOUS CONTOUR PLATEAU HAVING EMBOSS ELEMENTS THEREON AND PRODUCTS AND METHODS OF USING THE SAME
    Publication number: 20220112665
    Abstract: Embossed tissue products having improved strength and softness are disclosed. The products as described have a continuous curvilinear emboss element which carries discrete emboss elements, thereby providing the product with the softness and handfeel benefits associated with the long linear elements, but the visual appearance of discrete emboss elements.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 14, 2022
    Inventors: Brian J. Schuh, Steven R. Olson, Peter G. Anderson, Luke J. Van Den Plas, Michael D. Wishneski
  • Lightweight particles and compositions containing them
    Patent number: 11292937
    Abstract: Disclosed are particles that have an exterior surface coated with a thin polymeric coating, such as a coating that includes a sulfur-containing polymer. Also disclosed are compositions, such as fuel-resistant sealant and coating compositions, which include such particles. Aerospace vehicles having an aperture at least partially sealed with a sealant deposited from such a sealant composition are also disclosed.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: April 5, 2022
    Assignee: PPG Industries Ohio, Inc.
    Inventors: Lawrence G. Anderson, Chester J. Szymanski
  • Heat shield for a marine engine exhaust system
    Patent number: 11293325
    Abstract: A heat shield includes an outer jacket including a fluid inlet port and a fluid outlet port, and an inner jacket nested within the outer jacket and spaced apart therefrom to define a fluid passageway therebetween. The fluid passageway is in fluid communication with the fluid inlet port and the fluid outlet port for directing a cooling fluid from the fluid inlet port to the fluid outlet port through the fluid passageway. The inner jacket at least partially defines a main cavity configured to at least partially protect a turbocharger of the marine engine.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: April 5, 2022
    Assignee: Indmar Products Company, Inc.
    Inventor: Timothy G. Anderson
  • MOWER DECK TRANSPORT LOCK
    Publication number: 20220087100
    Abstract: A mower deck transport lock for a parallelogram lift linkage supporting a mower deck at any of a plurality of cutting heights where a striker plate contacts a height of cut selection knob. A transport bracket pivots into engagement with the striker plate only at a transport height above the plurality of cutting heights. A transport lock indicator is activated when the transport bracket pivots into engagement with the striker plate.
    Type: Application
    Filed: September 21, 2020
    Publication date: March 24, 2022
    Inventors: Jorge Cavazos Garcia, Maxwell G. Anderson, Sebastian Baena, Wesley E. Clontz
  • Compositions comprising nucleic acids and methods of using the same
    Patent number: 11279928
    Abstract: The disclosure relates to compositions comprising and methods for chemical modification of single guide RNA (sgRNA), tracrRNA and/or crRNA used individually or in combination with one another or Cas system components. Compositions comprising modified ribonucleic acids have been designed with chemical modification for even higher efficiency as unmodified native strand of sgRNA. Administration of modified ribonucleic acids will allow decreased immune response when administered to a subject, increased stability, increased editing efficiency and facilitated in vivo delivery of sgRNA via various delivery platforms. The disclosure also relates to methods of decreasing off-target effect of CRISPR and a CRISPR complex.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: March 22, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Hao Yin, Daniel G. Anderson, Robert Samuel Langer
  • Modified alginates for anti-fibrotic materials and applications
    Patent number: 11266606
    Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: March 8, 2022
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Arturo J. Vegas, Joshua C. Doloff, Omid Veiseh, Minglin Ma, Robert S. Langer, Daniel G. Anderson
  • NON-ROLL STICK PRODUCT CONTAINERS
    Publication number: 20220063878
    Abstract: The present invention relates to three stick product containers. One has a removable top cap with a crown and a hollow base, such that the top cap can be removed and inserted into the hollow base. The top cap has associated with it a thumb lever push ring to prevent the stick from rolling when laid horizontal. The other container is more suitable, for example, for a lip balm that has a top cap with a living hinge that can be flipped all the way back, inserted into a plug insert hole in the base of the cap, and then the cap is used to support the container in an at rest position to prevent it from rolling.
    Type: Application
    Filed: August 25, 2020
    Publication date: March 3, 2022
    Inventor: Raymond G. Anderson
  • MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS
    Publication number: 20220031913
    Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
    Type: Application
    Filed: July 15, 2021
    Publication date: February 3, 2022
    Inventors: Arturo Vegas, Joshua C. Doloff, Omid Veiseh, Minglin Ma, Robert S. Langer, Daniel G. Anderson
  • Circular RNA For Translation In Eukaryotic Cells
    Publication number: 20220025395
    Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.
    Type: Application
    Filed: October 1, 2021
    Publication date: January 27, 2022
    Inventors: Daniel G. Anderson, Robert Alexander Wesselhoeft, Piotr S. Kowalski
  • Multi-function air data probe having multi-hole ports used for determining angle of attack, total and static pressure values
    Patent number: 11215631
    Abstract: A multi-function air data probe comprises a probe stem having an outer surface that extends between a first end and an opposite second end, with the probe stem having a first cross-sectional diameter; and a probe head having an outer surface that extends between a proximal end and a distal end, wherein the proximal end of the probe head is coupled to the first end of the probe stem. The probe head has a second cross-sectional diameter that is larger than the first cross-sectional diameter of the probe stem. A plurality of multi-hole ports is located in the probe head, with the multi-hole ports extending into and through the probe stem. The air data probe is operative to make measurements used to determine one or more of angle of attack values, total pressure values, and static pressure values.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: January 4, 2022
    Assignee: Honeywell International Inc.
    Inventors: Morris G. Anderson, Grant A. Gordon
  • Drive-over mower deck with retractable front rollers
    Patent number: 11212961
    Abstract: A drive-over mower deck includes at least one retractable front roller which is pivotable between a lowered position extending forwardly and downwardly from a rim at a front and center of the drive-over mower deck, and a retractable position in which the front roller pivots freely between the lowered position and a retracted position when the drive-over mower deck lays flat on a ground surface.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: January 4, 2022
    Assignee: DEERE & COMPANY
    Inventors: Maxwell G. Anderson, Travis S. Mergener
  • Circular RNA For Translation In Eukaryotic Cells
    Publication number: 20210403944
    Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 30, 2021
    Inventors: Daniel G. Anderson, Robert Alexander Wesselhoeft, Piotr S. Kowalski
  • IONIZERS HAVING CARBON NANOTUBE ION EMITTING HEADS
    Publication number: 20210394202
    Abstract: Ionizers having carbon nanotube (CNT) ion emitting heads of the present invention include ionization circuitry supplying voltage at ionization potential and carbon nanotube (CNT) ion emitters operatively connected thereto. The carbon nanotube (CNT) ion emitters are mechanically and electrically stable, provide good ion flows for air purification and/or air invigoration when actuated at ionization potential and are capable of prolonged use in highly polluted environments.
    Type: Application
    Filed: June 18, 2021
    Publication date: December 23, 2021
    Inventors: Troy G. Anderson, Thomas A. Rounds, Andres A. Arrocha-Arcos
  • Circular RNA for translation in eukaryotic cells
    Patent number: 11203767
    Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f.) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: December 21, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Daniel G. Anderson, Robert Alexander Wesselhoeft, Piotr S. Kowalski
  • Curable Compositions Containing 1,1-Di-Activated Vinyl Compounds and Related Coatings and Processes
    Publication number: 20210371668
    Abstract: Curable compositions comprising 1,1-di-activated vinyl compounds are provided herein. Also provided are coatings formed from 1,1-di-activated vinyl compounds. Also provided are processes for coating substrates and articles. Curable compositions including 1,1-di-activated vinyl compounds that function as crosslinking agents are described.
    Type: Application
    Filed: August 12, 2021
    Publication date: December 2, 2021
    Applicant: PPG Industries Ohio, Inc.
    Inventors: Scott J. Moravek, Adam B. Powell, Lawrence G. Anderson, Scott W. Sisco, Davina J. Schwartzmiller, Aditya Gottumukkala
  • CIRCULAR RNA COMPOSITIONS AND METHODS
    Publication number: 20210371494
    Abstract: Circular RNA and transfer vehicles, along with related compositions and methods are described herein. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes a chimeric antigen receptor (CAR). In some embodiments, circular RNA of the invention has improved expression, functional stability, immunogenicity, ease of manufacturing, and/or half-life when compared to linear RNA. In some embodiments, inventive methods and constructs result in improved circularization efficiency, splicing efficiency, and/or purity when compared to existing RNA circularization approaches.
    Type: Application
    Filed: July 23, 2021
    Publication date: December 2, 2021
    Inventors: Alexander Wesselhoeft, Daniel G. Anderson, Shinichiro Fuse, Brian Goodman, Allen T. Horhota, Raffaella Squilloni