Abstract: Provided are a compound of formula (I), a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or a eutectic thereof, or a pharmaceutical composition comprising same, and use thereof as a ketohexokinase inhibitor in the preparation of drugs for treating related diseases. Each group in formula (I) is as defined in the description.

Abstract: Disclosed is a high ultraviolet blocking polylactic acid composite material reinforced by POSS modified bamboo powder. The preparation method therefor includes steps of carrying out chemical grafting modification of bamboo powder with proper particle size by using POSS containing specific organic groups, and then adding the modified bamboo powder to polylactic acid for melting and co-extrusion to obtain POSS modified bamboo powder. The present disclosure makes full use of the 30% lignin in the bamboo powder, having the advantages of wide source, biological metabolizability and low price; the present disclosure does not need the traditional inorganic ultraviolet blocking agent, nor need to extract refined lignin from natural materials, but directly takes inexpensive and easy-to-obtain bamboo powder as main raw material. The composite material prepared in the present disclosure can greatly improve the UV blocking performance, mechanical properties and thermal stability of the PLA.

Abstract: A structure multi-dimensional loading test system considering real complex boundary conditions considering real complex boundary conditions comprises a main part of machine, a base part, a hydraulic power supply and a control system. The system can simulate the load borne by a structure in a real working environment better and more accurately, realize multi-dimensional loading of the structure with six degrees of freedom in space and provide more real and valuable experimental data for the research on damage of reinforced concrete materials, components and structures under the action of an earthquake, and the research results will help researchers further reveal the damage mechanism of reinforced concrete structures, put forward the corresponding damage criteria and develop the corresponding seismic design methods.

Abstract: A lipid delivery system, a virus-like structure (VLS) vaccine constructed therefrom, and a lipid particle capable of encapsulating an mRNA molecule encoding a SARS-CoV-2-specific antigen are provided. After the lipid particle encapsulates an mRNA molecule encoding a SARS-CoV-2 antigen, a SARS-CoV-2 S1 antigen protein can be embedded on a surface of an envelope structure of the lipid under specific buffer conditions to produce a VLS vaccine with an antigen-encoding mRNA molecule encapsulated inside and an outer membrane presenting a required viral antigen protein. The vaccine has a superior specific antibody-inducing ability to a SARS-CoV-2 mRNA vaccine and a polypeptide vaccine, can maintain a long-lasting high antibody level, and can also exhibit excellent immune binding abilities for the emerging different variants.

Abstract: A low-power pulse output circuit comprises first to third PMOS transistors, first NMOS to third NMOS transistors, a resistor regulation module, a capacitor regulation module, an inverter and a buffer. Drains of the first PMOS and first NMOS transistors, gates of the first NMOS, second PMOS, second NMOS, and third NMOS transistors are connected. Drain of the second PMOS transistor, gate of the third PMOS transistor and one terminal of the resistor regulation module are connected. The other terminal of the resistor regulation module and drain of the second NMOS transistor are connected. Drain of the third PMOS transistor, drain of the third NMOS transistor and an input terminal of the inverter are connected. An output terminal of the inverter, the other terminal of the capacitor regulation module and an input terminal of the buffer are connected.

Abstract: A method for determining at least one object information item of at least one target object (18) which is sensed with a radar system (12) of a vehicle (10), a radar system (12) and a driver assistance system (12) are described. Transmission signals (32a, 32b, 32c) are transmitted into a monitoring range (14) of the radar system (12) with three transmitters (Tx1, Tx2, Tx3). Echoes, which are reflected at the at least one target object (18), of the transmission signals (32a, 32b, 32c) are received as received signals (34a, 34b, 32c) with at least two receivers (RxA, RxB, RxC, RxD). The received signals (34a, 34b, 34c) are subjected to at least one multi-dimensional discrete Fourier transformation. At least one target signal is determined from the result of the Fourier transformation. An object information item is determined from the target signal.

Abstract: A divisible device and a method for sand production and sand control experiment for natural gas hydrate exploitation. The experimental device includes a reactor system, a feeding system, a separation and measurement system, a water-bath jacket system, a support and safety system, and a software recording and analyzing system. In the reactor system, the reactor units can be combined in different ways depending on the experimental conditions and purposes. The reactor units include: left/right reactor units, secondary reactor units, central reactor units, and caps. The combination of a left/right reactor unit with a cap gives a hydrate formation reactor without sand control screens. Combining the left/right reactor unit, secondary left/right reactor units and central reactor units with other accessories allows the reactor system to carry out the simulation experiments with either zero, one, or two view zones, and with either one or two wells.

Abstract: For determining rotation of a de-energized electric machine without accessing the machine, wherein the machine in the energized state rotates in a reference direction, a computer system determines, for at least one waveform of at least one set of multi-phase electrical power indicia measured remotely from the machine, that a first time segment of the at least one waveform corresponds to an energized state of the machine and that a second time segment of the at least one waveform corresponds to a de-energized state of the machine. The computer system also determines that the machine in the de-energized state has rotated in a direction reverse to the reference direction, wherein the determining that the machine in the de-energized state has rotated in a direction reverse to the reference direction includes comparing the first and second time segments of the at least one waveform.

Abstract: A process for producing solid carbon and gaseous oxygen from CO2 via electrolysis using an electrolysis apparatus is disclosed. The apparatus includes a chamber with an electrolyte inlet, an electrolyte outlet, a liquid electrolyte containing CO2 in the chamber, at least one cathode-anode pair, with the cathode including a liquid metal capable of catalysing reduction of CO2 to solid carbon at a selected operating temperature of the process. The process includes causing the electrolyte to flow from the inlet to the outlet in fluid communication with the cathode-anode pair, applying a voltage between the cathode-anode pair and causing solid carbon to form on the cathode from CO2 in the electrolyte and gaseous oxygen to be evolved at the anode from CO2 in the electrolyte.

Abstract: An invention provides a lens assembly. The lens assembly includes a first substrate, a lens, a first memory alloy wire and a second memory alloy wire, wherein the lens is placed in the first substrate, and the first substrate includes a first side plate and a second side plate that are placed on both sides of the lens. The optical image stabilization lens assembly has the advantages of a simple structure for realizing optical image stabilization and being able to realize miniaturized design. In addition, an optical image stabilization method for the lens assembly is provided.

Abstract: Provided is a display method for A-pillar-mounted display assemblies of a vehicle. The method includes: acquiring facial posture information of a driver of the vehicle in a camera coordinate system by any one driver monitoring assembly of at least one driver monitoring assembly, determining a visual field of the driver based on a gaze direction of the driver and the eye position of the driver, acquiring coordinates of the two display assemblies in a world coordinate system, converting the coordinates of the two display assemblies in the world coordinate system into coordinates in the camera coordinate system based on a first conversion relationship, determining whether any one display assembly of the two display assemblies is within the visual field, and capturing an external image of the vehicle captured by the imaging assembly.

Abstract: Disclosed are a salt form used as a CDC7 inhibitor and a crystal form thereof, and specifically disclosed is a compound represented by formula (II), a crystal form thereof, a preparation method thereof, and an application thereof in the preparation of a drug for preventing or treating tumors.

Abstract: A comprehensive three-dimensional exploitation experimental system for large-scale and full-sized exploitation wells includes a reactor, configured to prepare a natural gas hydrate sample, for simulating an environment for forming a natural gas hydrate reservoir in seafloor sediments. The reactor includes a reactor body, an upper cover disposed at an upper surface of the reactor body, and a lower cover disposed at a lower surface of the reactor body; a gas introducing module, configured to introduce gas to the reactor during hydrate formation; a liquid introducing module, configured to introduce liquid to the reactor during hydrate formation; a temperature regulating module, configured to regulate a temperature in the reactor; a data collecting-processing-displaying module, configured to collect, store, process and display data of the comprehensive three-dimensional exploitation experimental system during an experiment.

Abstract: An ultrasonic-assisted heat press machine, includes a frame, a material tank, an extruder, an ultrasonic wave generator, and a heater. The material tank is disposed on the frame and includes a cavity for accommodating an oil-bearing raw material. The extruder is extended in the cavity. The ultrasonic wave generator is disposed on the frame and adjacent to the material tank. The heater is disposed on the frame and adjacent to the material tank. The heater is configured to produce heat to heat the cavity and the ultrasonic wave generator, and regulate the working frequency of the ultrasonic wave generator. When in use, the heater, the extruder, and the ultrasonic wave generator cooperate to separate oil from the oil-bearing raw material in the material tank.

Abstract: This application discloses a map generation method and apparatus, an electronic device, and a computer storage medium. The method includes: selecting a plurality of sub-level maps from a sub-level map library; sequentially placing first M sub-level maps of the plurality of sub-level maps in a predetermined map region, the first M sub-level maps being all located in the map region, and the first M sub-level maps not overlapping with each other; and sequentially placing the remaining sub-level maps not to overlap with the sub-level maps placed in the map region and to be connected to at least one of the sub-level maps placed in the map region, to obtain a target map.

Abstract: A modular rapping dust remover, comprising: a dust-air chamber, wherein at least one air inlet is provided in the top of the dust-air chamber, and at least one dust outlet is provided in the bottom of the dust-air chamber; an air intake pipeline, wherein an air output end of the air intake pipeline is in communication with the air inlet of the dust-air chamber; a plurality of filtering members, wherein the plurality of filtering members are arranged inside the dust-air chamber, and a gap is provided between two adjacent filtering members; at least one rapping device arranged in the dust-air chamber, wherein the rapping device can drive the plurality of filtering members to vibrate; at least one air purification chamber; and an air output pipeline, an air intake end of the air output pipeline being in communication with an air outlet of the air purification chamber.

Abstract: A tidal current energy converter including an infinitely variable transmission (IVT) control system and a hybrid vertical axis wind (or water) turbine (VAWTs) apparatus. The hybrid VAWT apparatus includes a modified-Savonius (MS) rotor in the central region and a straight bladed H-type Darrieus rotor in the surrounding annular region. The IVT control system includes a nonlinear closed-loop control combined with an integral time-delay feedback control to adjust a speed ratio of the IVT. A speed ratio control for an IVT system involves a forward speed controller and/or a crank length controller for different speed ranges. The time-delay control is designed to reduce speed fluctuations of the output speed of an IVT with an accurate speed ratio. The speed ratio of an IVT with the disclosed control strategy can achieve an excellent tracking response for the desired constant output speed and reduce speed fluctuations of the output speed of an IVT by the time-delay feedback control.

Abstract: A casting and outputting system is provided. The system includes a casting machine, a disc body, a transfer device, a special fixture, a cooling tank, a collection device and a waste plate rack. The transfer device is configured to drive the special fixture to take out anode plates cast on the disc body, place a qualified one of the anode plates in the cooling tank, place an unqualified one of the anode plates on the waste plate rack, lift the anode plate cooled in the cooling tank, and place the cooled anode plate on the collection device for stacking.

Abstract: A display device includes an optical diffuser configured to, in response to receiving image light, output diffused image light having a same polarization as the image light. The optical diffuser is also configured to transmit ambient light. The display device also includes an optical assembly that includes a substrate, a reflector coupled to the substrate, and a beam splitter coupled to the substrate. The optical assembly is configured to transmit the diffused image light at a first optical power by reflecting the diffused image light at the reflector and at the beam splitter and to transmit the transmitted ambient light at a second optical power that is less than the first optical power without reflection at the reflector or the beam splitter. A method for transmitting light through the display device is also disclosed.

Abstract: Provided is a prism device applied to a periscope lens module. The prism device includes: a bearing frame; a supporting-restoring assembly; a prism; and shape memory alloy wires. The bearing frame includes a horizontal support plate, a vertical support plate, and two side plates. The shape memory alloy wires are connected to the supporting-restoring assembly and the bearing frame from the two side plates, respectively, so as to drive the supporting-restoring assembly to drive the prism to rotate about a first rotation center axis, and are connected to the supporting-restoring assembly and the bearing frame from the horizontal support plate and the vertical support plate, respectively, so as to drive the supporting-restoring assembly to drive the drive the prism to rotate about a second rotation center axis. The present invention replaces the electromagnetic driving with the shape memory alloy wire, thereby reducing a manufacturing cost.