Abstract: A computer-based system and method calculates and facilitates periodic revenue accrual for making larger, less frequent payments of estimated taxes by electronic messaging. A service host enables a plurality of payers to make set-asides at various levels as needed, on an individual or batch basis. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. Automatic data links move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. The service host provides individual or batch taxpayer enrollment with the taxing authority for tax payment by electronic messages, and makes the tax payments by transmission of individual payment messages or by batch file transmission to the taxing authority.

Abstract: A light extracting device includes a dual light generating unit and a first order Bragg grating unit. The dual light generating unit is for receiving an input optical signal and a control signal, and for generating from the input optical signal first and second optical signals that have a phase difference there between. The phase difference is associated with the control signal. The first order Bragg grating unit is for receiving the first and second optical signals from the dual light generating unit, and for causing optical interference to occur between the first and second optical signals within a predetermined wavelength range to result in first and second output optical signals.

Abstract: A light extracting device includes a dual light generating unit and a first order Bragg grating unit. The dual light generating unit is for receiving an input optical signal and a control signal, and for generating from the input optical signal first and second optical signals that have a phase difference there between. The phase difference is associated with the control signal. The first order Bragg grating unit is for receiving the first and second optical signals from the dual light generating unit, and for causing optical interference to occur between the first and second optical signals within a predetermined wavelength range to result in first and second output optical signals.

Abstract: A computer-based system and method calculates and facilitates periodic revenue accrual for making larger, less frequent payments of estimated taxes by electronic messaging. A service host enables a plurality of payers to make set-asides at various levels as needed, on an individual or batch basis. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. Automatic data links move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. The service host provides individual or batch taxpayer enrollment with the taxing authority for tax payment by electronic messages, and makes the tax payments by transmission of individual payment messages or by batch file transmission to the taxing authority.

Abstract: A computer-based system and method calculates and facilitates revenue accrual, for making larger, less frequent payments of estimated taxes or other obligations. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. The system may be self-contained, handheld, or accessed remotely. Automatic datalinks move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. A service host may support a plurality of payers to make set-asides and payments at various levels as needed, on an individual or batch basis, including individual taxpayer enrollment for batch file tax payments by service providers. Some embodiments can be embedded to enhance the capabilities of other systems.

Abstract: A computer-based system and method calculates and facilitates revenue accrual, for making larger, less frequent payments of estimated taxes or other obligations. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. The system may be self-contained, handheld, or accessed remotely. Automatic datalinks move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. A service host may support a plurality of payers to make set-asides and payments at various levels as needed, on an individual or batch basis, including individual taxpayer enrollment for batch file tax payments by service providers. Some embodiments can be embedded to enhance the capabilities of other systems.

Abstract: A computer-based system and method calculates and facilitates revenue accrual, for making larger, less frequent payments of estimated taxes or other obligations. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. The system may be self-contained, handheld, or accessed remotely. Automatic datalinks move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. A service host may support a plurality of payers to make set-asides and payments at various levels as needed, on an individual or batch basis, including individual taxpayer enrollment for batch file tax payments by service providers. Some embodiments can be embedded to enhance the capabilities of other systems.

Abstract: The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are accommodated in a passage bounded by a first step, but at least some of the particles are unable to pass through a narrower passage bounded by a second step, resulting in segregation of the particles. The apparatus and methods described herein can be used to segregate particles of a wide variety of types. By way of example, they can be used to segregate fetal-like cells from a maternal blood sample such as maternal arterial blood.

Abstract: A computer-based system and method calculates and facilitates revenue accrual, for making larger, less frequent payments of estimated taxes or other obligations. Payer preferences are applied to satisfy variable payment intervals, amounts, and available resources. The obligation, required payments, and set-aside schedules are recalculated as needed, under payer and/or system control. Excess accruals are minimized; set-aside schedules are configurable. The system may be self-contained, handheld, or accessed remotely. Automatic datalinks move information and command fund transfers from the payer's bank, to accrue funds and make payments to other accounts. A service host may support a plurality of payers to make set-asides and payments at various levels as needed, on an individual or batch basis, including individual taxpayer enrollment for batch file tax payments by service providers. Some embodiments can be embedded to enhance the capabilities of other systems.

Abstract: A system and method for displaying a three-dimensional image of airspace includes a series of translucent, horizontal “pavers” that lie like stepping stones marking the selected flight path. In addition, the display includes a series of vertical rectangles—called “wickets”—which bracket the selected flight path. One or more of the wickets may include a graphical representation of the direction of the aircraft should be flying through the wicket. The system accommodates changes in course by generating a new flight path when instructed to do so. The new flight path is created in a way that assures continuous guidance for the pilot and sufficient time for the pilot to adjust to the new course. The display can include a compass rose which indicates the aircraft's present heading and direction of flight.

Abstract: Laser diodes are formed with an outcoupling grating between two separate distributed Bragg reflectors. The devices have gain regions located between the reflector gratings for pumping the active region. The outcoupling grating couples light out of the waveguide normal to the surface if the grating spacings are equal to an integer number of wavelengths of the light within the cavity. If the gratings are not such an integer number, the light is coupled out of the cavity off the normal.

Abstract: Improved transition state analog inhibitors of ricin toxin-A are provided. Methods of using those inhibitors to inhibit ricin toxin-A and to prevent the toxic effects of rich toxin-A in a mammal are also provided.

Abstract: A semiconductor device system includes a chamber, one or more semiconductor devices disposed within the chamber and operable to emit light, and an insulator fluid disposed within the chamber. The insulator fluid may be in contact with the semiconductor devices and operable to decrease the temperature of the semiconductor devices. The insulator fluid may comprise deionized water.

Abstract: The present invention relates to a new process for the preparation of compounds of general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5?-methylthioadenosine phosphorylases (MTAP), 5?-methylthioadenosine nucleosidases (MTAN) and/or nucleoside hydrolases (NH).The present invention relates to a new process for the preparation of compounds of general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5?-methylthioadenosine phosphorylases (MTAP), 5?-methylthioadenosine nucleosidases (MTAN) and/or nucleoside hydrolases (NH).

Abstract: A surface emitting semiconductor laser system having four cavities that couple light from a single aperture. Each of the four cavities overlaps at the outcoupling aperture. Each cavity is fabricated to resonate at a different central wavelength, outputting a different frequency of light, each of which can be independently modulated.

Abstract: A surface emitting semiconductor laser system having an outcoupling aperture on a central waveguide. At either end of the central waveguide are means for reflecting a plurality of different wavelengths of light such that multiple wavelengths are outcoupled through a single outcoupling aperture. Means are provided by which the different wavelengths can be independently modulated.

Abstract: A single-mode grating-outcoupled surface emitting (GSE) semiconductor laser architecture is provided. This architecture enables high speed modulation of the GSE laser, which is accomplished by only varying the relative phase of counter propagating waves in the outcoupler grating region of the lasing cavity.

Abstract: The present invention relates to compounds of the general formula (I) which are inhibitors of purine muclioside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5?-methylthioadenosine phosphorylases (MTAP), 5?-methylthioadenosine mucliosidases (MTAN) and/or nucleoside hydrolases (NH). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.

Abstract: An improved grating-outcoupled surface-emitting semiconductor laser architecture is provided. A second-order grating is placed between two distributed Bragg reflector gratings. The period of the second order grating is positively or negatively detuned from the distributed Bragg reflector selected optical wavelength at which the laser operates. Detuning of the second-order grating towards shorter or longer wavelengths allows kink-free, linear LI curves light output versus forward current) for grating-outcoupled surface-emitting lasers. Due to the detuning of the outcoupler grating, the outcoupled radiation emits two beams that deviate slightly from the normal axis. A design point may then be chosen where the power coutcoupled by symmetric and antisymmetric modes cross and where the outcoupled power is independent of the phase variation.

Abstract: Laser diodes are formed with an outcoupling grating between two separate distributed Bragg reflectors. The devices have gain regions located between the reflector gratings for pumping the active region. The outcoupling grating couples light out of the waveguide normal to the surface if the grating spacings are equal to an integer number of wavelengths of the light within the cavity. If the gratings are not such an integer number, the light is coupled out of the cavity off the normal.