Abstract: A system includes a radio configured to transmit and receive voice transmissions to and from air traffic control (ATC), the radio installed onboard an aircraft. The system includes a processor communicatively coupled to the radio and installed onboard the aircraft. The processor is configured to: receive an ATC voice command via the radio; transcribe the ATC voice command into an ATC command; and when the ATC command includes an aircraft identification associated with the aircraft, categorize the ATC command into components, each of the components being categorized based on a criticality level associated with said component, wherein the criticality level is or is associated with a required accuracy confidence level of transcribed speech for a given component.

Abstract: A system includes a radio configured to transmit and receive voice transmissions to and from air traffic control (ATC), the radio installed onboard an aircraft. The system includes a processor communicatively coupled to the radio and installed onboard the aircraft. The processor is configured to: receive an ATC voice command via the radio; transcribe the ATC voice command into an ATC command; and when the ATC command includes an aircraft identification associated with the aircraft, categorize the ATC command into components, each of the components being categorized based on a criticality level associated with said component, wherein the criticality level is or is associated with a required accuracy confidence level of transcribed speech for a given component.

Abstract: A system and method are disclosed for design of a suite of multispectral (MS) sensors and processing of enhanced data streams produced by the sensors for autonomous aircraft flight. The onboard suite of MS sensors is specifically configured to sense and use a MS variety of sensor-tuned objects, either strategically placed objects and/or surveyed and sensor significant existing objects to determine a position and verify position accuracy. The received MS sensor data enables an autonomous aircraft object identification and positioning system to correlate MS sensor data output with a-priori information stored onboard to determine and verify position and trajectory of the autonomous aircraft. Once position and trajectory are known, the object identification and positioning system commands the autonomous aircraft flight management system and autopilot control of the autonomous aircraft.

Abstract: A physiological state screening system may include a temperature sensor, a blood oxygen saturation sensor, a cardiorespiratory sensor unit, a communication circuitry, and one or more controllers. The one or more controllers may include one or more processors communicatively coupled to the temperature sensor and the cardiorespiratory sensor unit. The one or more processors may be configured to execute a set of program instructions maintained in one or more memory units, where the set of program instructions is configured to cause the one or more processors to receive one or more signals, determine one or more physiological states of a subject, determine one or more physiological interventions, and transmit one or more signals instructive of the one or more physiological interventions.

Abstract: A system and method are disclosed for design of a suite of multispectral (MS) sensors and processing of enhanced data streams produced by the sensors for autonomous aircraft flight. The suite of MS sensors is specifically configured to produce data streams for processing by an autonomous aircraft object identification and positioning system processor. Multiple, diverse MS sensors image naturally occurring, or artificial features (towers buildings etc.) and produce data streams containing details which are routinely processed by the object identification and positioning system yet would be unrecognizable to a human pilot. The object identification and positioning system correlates MS sensor output with a-priori information stored onboard to determine position and trajectory of the autonomous aircraft. Once position and trajectory are known, the object identification and positioning system sends the data to the autonomous aircraft flight management system for autopilot control of the autonomous aircraft.

Abstract: A system and method operate to leverage high assurance positioning systems to determine a hybrid deviation from an expected position, altitude, and path to generate a lateral and vertical signal indicating deviation from a desired position. As a filtered or alternative to conventional precision landing systems, the hybrid positioning system receives sensor data from a plurality of sensors and compares the received sensor data to known values to determine a deviation of position and trajectory. Extending the capability of existing auto-land systems, relative-to-runway sensors and/or filtered high assurance hybrid solutions are employed as an alternative to conventional precision landing systems. The sensors provide position data that is compared to an expected position and path to provide deviations in lateral, vertical, and speed augmenting traditional RF-based systems.

Abstract: A head wearable device, a method, and a system. The head wearable device may include a transparent display and a non-transparent display. The transparent display may be implemented in or on the head wearable device. The transparent display may be configured to present first content to a user of the head wearable device. The non-transparent display may be implemented in or on the head wearable device. The non-transparent display may be configured to present second content to the user of the head wearable device. The non-transparent display may be viewable at least in part through the transparent display.

Abstract: A system and method are disclosed for design of a suite of multispectral (MS) sensors and processing of enhanced data streams produced by the sensors for autonomous aircraft flight. The onboard suite of MS sensors is specifically configured to sense and use a MS variety of sensor-tuned objects, either strategically placed objects and/or surveyed and sensor significant existing objects to determine a position and verify position accuracy. The received MS sensor data enables an autonomous aircraft object identification and positioning system to correlate MS sensor data output with a-priori information stored onboard to determine and verify position and trajectory of the autonomous aircraft. Once position and trajectory are known, the object identification and positioning system commands the autonomous aircraft flight management system and autopilot control of the autonomous aircraft.

Abstract: Systems and methods provide providing predictive radio tuning for an aircraft. The systems and methods electronically receive data from an off aircraft source and integrate with aircraft sourced data. The information is related to frequencies for aircraft radios at one or more locations. The systems and methods electronically determine a location of the aircraft, electronically provide a predicted frequency in response to the location and the information using a radio tuning application, and display the predicted frequency on a radio tuning panel on an electronic display.

Abstract: A head wearable device, a method, and a system. The head wearable device may include a transparent display and a non-transparent display. The transparent display may be implemented in or on the head wearable device. The transparent display may be configured to present first content to a user of the head wearable device. The non-transparent display may be implemented in or on the head wearable device. The non-transparent display may be configured to present second content to the user of the head wearable device. The non-transparent display may be viewable at least in part through the transparent display.

Abstract: A head wearable device, a method, and a system. The head wearable device may include a display, a head tracking system, a user input system, and a processor. The processor may be configured to output a stream of image data to the display for presentation to the user, the image data associated with images aligned with a determined position and a determined orientation of the head of the user relative to an environment, the images including a user-selectable depiction of a teamed asset. The processor may be further configured to receive user input data from the user input system, wherein the user input data includes user selection data associated with a selected teamed asset. The processor may be further configured to update the stream of image data associated with the images such that the images further include a depiction of information associated with the selected teamed asset.

Abstract: Head-worn displays are disclosed. A head-worn display may include at least one processor configured to determine a location of the head-worn display with respect to a real-world environment and to generate a conformal indicator conforming to an element in the real-world environment. The at least one processor may also be configured to generate a non-conformal indicator unconstrained by elements in the real-world environment. The head-worn display may include at least one display in communication with the at least one processor. The at least one display may be configured to display the conformal indicator and/or the non-conformal indicator generated by the at least one processor to a user.

Abstract: An on aircraft computer system records and analyzes biometric data to identify indicia of impaired performance, such as pilot fatigue, attention tunneling, or cognitive overload. Such impairment is identified by alterations in pilot gaze or eye movement, head movement, facial parameters, eye lid position, heart rate, breathing, or brain wave patterns. Appropriate corrective action is applied based on the type of impaired performance identified, including altering a level of automation, contacting a ground dispatcher or ground pilot, or contacting a co-pilot or other crew member. Biometric data is continuously logged and correlated with data from other avionics systems to refine formulas relating biometric data to states of alertness and crew rest procedures.

Abstract: A head wearable device, a method, and a system. The head wearable device may include a display, a head tracking system, a user input system, and a processor. The processor may be configured to output a stream of image data to the display for presentation to the user, the image data associated with images aligned with a determined position and a determined orientation of the head of the user relative to an environment, the images including a user-selectable depiction of a teamed asset. The processor may be further configured to receive user input data from the user input system, wherein the user input data includes user selection data associated with a selected teamed asset. The processor may be further configured to update the stream of image data associated with the images such that the images further include a depiction of information associated with the selected teamed asset.

Abstract: A system and method for an interactive avionics display system integrates a large-format primary avionics display, a secondary avionics display capable of mirroring the display of electronic flight bag mobile devices, a format selector panel, and a keyboard panel. Background displays and foreground multifunction windows generated by the display system house applications and display relevant avionics data. The multifunction windows can be resized or repositioned on the display surface using finger contacts and gestures. Format selector panels include control selectors corresponding to the multifunction windows, the control selectors responsive to finger contact with the format selector panels or the corresponding multifunction windows. Keyboard panels provide touch-sensitive radio and communications controls as well as an alphanumeric keyboard responsive to finger contact with text fields generated by the display.

Abstract: The present disclosure is directed to a method for managing a graphical interface viewable on a display. The method may include the step of presenting a plurality of layout options, a layout option is at least one of a full window layout or a divided window layout. The method may also include the step of receiving a selection of a layout option from the plurality of layout options. A further step of the method includes presenting a preview of the selected layout option on the display. The method also includes the step of presenting a plurality of icons, each icon corresponding to an application. A further step of the method includes receiving a selection of an icon for display within the selected layout option, the selected icon being compatible for display in the selected layout option.

Abstract: The present invention is a flight deck situational awareness communication system for providing integrated controller to pilot data link communication (CPDLC) message function for an aircraft. The system includes a memory configured for receiving and storing a CPDLC message from a communicatively coupled remote CPDLC communication system. The flight deck system further includes a processor. The processor is communicatively coupled with the memory and configured for receiving the CPDLC message stored in the memory. The processor is further configured for generating an image including a depiction of the content of the received CPDLC message overlaid onto an application depiction. The processor is communicatively coupled with a display and provides the image to the display. The display is configured for receiving and displaying the image.

Abstract: A first aspect of the invention relates to a method of treating a proliferative disorder in a subject, said method comprising administering to the subject a therapeutically effective amount of (i) sapacitabine, or a metabolite thereof; and (ii) seliciclib; in accordance with a dosing regimen comprising at least one first treatment cycle and at least one second treatment cycle, wherein said first treatment cycle comprises: (a) administering a therapeutically effective amount of sapacitabine, or a metabolite thereof, for 3 to 5 consecutive days for 2 weeks, starting on day d, where d is the first day of treatment with sapacitabine, or the metabolite thereof, in said first treatment cycle; and (b) optionally administering a therapeutically effective amount of seliciclib for 3 to 5 consecutive days for 2 weeks, starting on day (d?1) relative to the administration of sapacitabine or the metabolite thereof, in said first treatment cycle; followed by a rest period of at least 2 weeks, or until treatment-related toxi