Abstract: An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

Abstract: A method of identifying an object in an image is disclosed. At least one feature map for each of a plurality of cells in the image is determined. A self-dissimilarity between a first feature map associated with a first one of said cells and a second feature map associated with a second cell, is determined. The self-dissimilarity is determined by determining a sum over thresholds of a difference in area between the first feature map and the second feature map. An appearance signature for the object is formed based on the determined self-dissimilarity. A distance between the appearance signature of the object in the image and appearance signatures of each of a plurality of further objects is determined. The object in the image is identified based on the determined distances.

Abstract: A method of determining a vertical medial axis of an object in an input image, is disclosed. A measure of horizontal symmetry is determined for each pixel of the image. First and second vertical bounds within the image are determined. A continuous path between the first and second vertical bounds is determined based on the horizontal symmetry measure, the continuous path representing the vertical medial axis of the object.

Abstract: 6-Amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically effective amounts of the 6-aminoisoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, obesity and glaucoma are also provided.

Abstract: The disclosure provides for methods, compositions, and kits for multiplex nucleic acid analysis of single cells. The methods, compositions and systems may be used for massively parallel single cell sequencing. The methods, compositions and systems may be used to analyze thousands of cells concurrently. The thousands of cells may comprise a mixed population of cells (e.g., cells of different types or subtypes, different sizes).

Abstract: A method of detecting a supporting surface region in an image captured by a camera is disclosed. An object in the image is detected. One or more regions of the image in which a lower part of the detected object exists are determined. A degree of confidence for each of the regions is determined. The degree of confidence indicates likelihood of a corresponding region being a supporting surface region. One or more of the regions are selected based on each corresponding degree of confidence. Similarity of other regions in the image to at least one of the selected regions is determined. The supporting surface region is detected based on the determined similarity.

Abstract: A method of identifying, with a camera, an object in an image of a scene, by determining the distinctiveness of each of a number of attributes of an object of interest, independent of the camera viewpoint, determining the detectability of each of the attributes based on the relative orientation of a candidate object in the image of the scene, determining a camera setting for viewing the candidate object based on the distinctiveness of an attribute, so as to increase the detectability of the attribute, and capturing an image of the candidate object with the camera setting to determine the confidence that the candidate object is the object of interest.

Abstract: A method of determining a boundary of an obstacle which occludes an object in an image, is disclosed. At least one object in the image and a further image captured by a camera is determined. A plurality of regions in which the at least one object is detected, is determined from the images. Locations of edges of the plurality of regions are determined A common location is determined from the determined edges. The boundary of the obstacle is determined, where the boundary comprises a part of the edges at the common location.

Abstract: A method and system of providing a mist in a grocery display that injects biocidal solution into a misting line of water during a phase of the misting cycle.

Abstract: The disclosure provides for methods, compositions, and kits for multiplex nucleic acid analysis of single cells. The methods, compositions and systems may be used for massively parallel single cell sequencing. The methods, compositions and systems may be used to analyze thousands of cells concurrently. The thousands of cells may comprise a mixed population of cells (e.g., cells of different types or subtypes, different sizes).

Abstract: An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

Abstract: The disclosure provides for methods, compositions, and kits for multiplex nucleic acid analysis of single cells. The methods, compositions and systems may be used for massively parallel single cell sequencing. The methods, compositions and systems may be used to analyze thousands of cells concurrently. The thousands of cells may comprise a mixed population of cells (e.g., cells of different types or subtypes, different sizes).

Abstract: An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

Abstract: A bone fixation device (1) comprising: A) a first bone implant (2) with at least one through hole (11) having an upper opening (3) with the area A and a lower opening (4) in the case of a bone plate (10) as the first bone implant (2); or an outer opening with the area A and an inner opening in the case of a hollow intramedullary nail as the first bone implant (2); B) at least one second bone implant (5) with a head (6) and a shaft for insertion into one or more of said through holes (11); and C) at least one closing cover (7) for closing said upper opening (3) or outer opening of said through hole (11) for preventing bone and soft tissue ingrowth and/or bacterial invasion into said through hole (11) and into said second bone implant (5) wherein said closing cover (7) is D) removably attachable to said first bone implant (2); and E) dimensioned and shaped in such a way that upon attachment to said first bone implant (2) it is apt to cover at least the entire area A of said upper opening (3) or outer opening an

Abstract: 6-Amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically effective amounts of the 6-aminoisoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, obesity and glaucoma are also provided.

Abstract: A method of determining a property of an image (176) captured by a camera (127), is disclosed. Vanishing points (320, 330, 340) in the image (176). Each pixel of the image (176) is associated with one or more of the vanishing points (320, 330, 340) based on an orientation of the image gradient at the pixel. The image is partitioned into a set of regions associated with a pair of the determined vanishing points based on the vanishing point associations for pixels in the image (176). Boundaries of the regions are aligned with the associated vanishing points. For at least one of the plurality of regions, a confidence value is determined for the property of the image based on pixels in the region. The property of the image is determined for one or more pixels within the image (176) based on the confidence value.

Abstract: An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

Abstract: 6-Amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically effective amounts of the 6-aminoisoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, obesity and glaucoma are also provided.

Abstract: 6- and 7-amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically effective amounts of the 6- and 7-aminoisoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, obesity and glaucoma are also provided.

Abstract: Data traffic, such as wireless data traffic egressing to the Internet, is aggregated at one or more regional aggregation hubs, and a portion(s) of data traffic associated with a subscriber(s) of interest is captured at the regional aggregation hub(s). Data traffic associated with subscribers can be aggregated at an access concentrator(s) and respective public Internet Protocol (IP) addresses can be given to respective subscribers. The data traffic can be aggregated at the regional aggregation hub(s) and data traffic associated with a subscriber(s) of interest can be identified based at least in part on the public IP address(es) of the respective subscriber(s) of interest. The data traffic associated with a subscriber(s) of interest can be captured and provided to a consumer (e.g., law enforcement, service provider) who desires such data.