Abstract: The present invention refers to a method for inducing tumor apoptosis by influencing the ROS (reactive oxygen species) signaling pathway in tumor cells. Increasing the level of ROS leads to the selective inactivation of a tumor cell catalase and subsequently to an apoptosis of these cells. The level of ROS can be increased by increasing the level of nitric oxide through inhibition of the enzymes nitric oxide dioxygenase or arginase. According to the present invention inhibitors of the nitric oxide dioxygenase or arginase can be used for the manufacture of a medicament for the treatment of cancer. The present invention further provides a method for identifying compounds which can be used for the treatment of cancer, wherein the method allows to specifically identify compounds which induce apoptosis through the ROS signaling pathway. The present invention also provides a kit for identifying compounds which induce tumor apoptosis by inactivating a catalase on the tumor cell surface.

Abstract: A driver information system is provided for a vehicle having at least one instrument, which has a front plate and an illumination device. At least one light-transmitting area is arranged in the front plate and the illumination device is arranged behind the front plate, the illumination device being able to emit light through the at least one light-transmitting area of the front plate. A polarization filter is arranged between the front plate and the illumination device. The polarization filter is oriented opposite to a polarization direction of a windshield of the vehicle.

Abstract: A third brake light for a motor vehicle includes, but is not limited to a light source, a light-guiding element with a decoupling structure defining a decoupling side of the light-guiding element, and an LCD-shutter. The LCD-shutter is arranged on a side of the light-guiding element facing away from the decoupling side.

Abstract: A tamper-proof security element includes at least one polymer spacer layer and two metal cluster layers. One or more of the layers, in addition to their function, fulfills a security feature in their color-shift set-up.

Abstract: The invention relates to a method for producing tamper-proof identification elements, and to tamper-proof identification elements produced according to said method and consisting respectively of at least one layer (2) reflecting electromagnetic waves (3), a spacer layer, and a layer consisting of metallic clusters (4). According to said method, a partial or all-over layer reflecting electromagnetic waves is applied to a carrier substrate (1), followed by at least one partial and/or all-over polymer layer having a defined thickness (3), and a layer consisting of metallic clusters which is produced by means of a method using vacuum technology or from systems based on solvents is then applied to said spacer layer(s).

Abstract: The invention relates to a platelike color effect pigment having the following structure: a) a metallic reflective core; b) a spacer layer made of a dielectric material, and; c) an, all in all, semitransparent absorber layer comprising, in essence, discrete metal particles that have an average diameter of 1 to 100 nm and optionally at least one other protective layer.

Abstract: The present invention relates to the field of analyzing the age and/or quality of certain natural products, for example foods. The invention also relates to devices for analyzing said age and/or quality as well as to methods for preparing such devices, to methods for analyzing natural products and to their use.

Abstract: A sensor arrangement for determining an inside temperature in a motor vehicle having a climate control device and at least a panel is at least a part of a control part of the climate control device, where the sensor arrangement includes a housing with at least a front wall and a rear wall, the housing is filled with a heat-insulating material, a first temperature sensor attached to a rear of the front wall and a second temperature sensor attached to an inner side of the rear wall, said inner side facing a rear of the front wall, and where the front wall is a part of the panel of the motor vehicle.

Abstract: A medical supply unit includes a bus system for transmitting instructions of control elements to actuators. The bus system is provided with transmitters and receivers being connected to each other by a transmission system. Via the transmission system, commands of the transmitters are transmitted, which are controlled by the control elements, and the responsive receiver transfers the command to a switching instruction at an output of the responsive receiver so as to control an actuator.

Abstract: A medical supply unit is provided including at least one carrier provided with coupling devices with fixing rails. In the fixing rails, fixing elements of an adapter engage, which are locked in the fixing rail by an operating means actuated by hand by means of a locking means.

Abstract: The present invention relates to the field of analyzing the age and/or quality of certain natural products, for example foods. The invention also relates to devices for analyzing said age and/or quality as well as to methods for preparing such devices, to methods for analyzing natural products and to their use.

Abstract: A sensor arrangement is provided for determining an interior temperature in a motor vehicle, which sensor arrangement is at least one part of an air-conditioning operating part, comprising a closed housing having at least one front wall and one rear wall, wherein the front wall is manufactured from a material which ensures satisfactory thermal transfer and the housing and is filled with a thermally insulating means, further comprising a first temperature sensor which is fastened to a rear side of the front wall and a second temperature sensor which interacts with the first temperature sensor at least in relation to an evaluation of the interior temperature, wherein the at least second temperature sensor is fastened on an inner side of the rear wall which faces the rear side of the front wall.

Abstract: A medical supply unit including a carrier with longitudinal edges and longitudinal faces is provided such that the longitudinal faces are provided with openings at the faces of which resilient fastener elements are provided. These resilient fastener elements engage in built-in modules forming a part of one of the longitudinal faces in order to form a positive connection with the built-in modules.

Abstract: The invention relates to a device for checking the authenticity of an anti-forgery marking with colors which change depending on the angle of observation, comprising a) several first light sources, emitting in a given spectral range, whereby the light sources are different from each other with regard to the wavelength of the emission maximum thereof and the first light sources (1) are housed in a housing (5) such as to irradiate the surface (O), with the housing (5) placed thereon, at a given first angle (?1), b) a first means (2) for measuring the intensity of the light reflected from the surface (O) arranged at a second angle (?2) and c) a means (7) for the automatic comparison of measured intensities with the reference intensities stored for at least one given color for each light source (1).

Abstract: The invention relates to a method of producing a flat facing material (6) with a gliding surface (5) for a running sole of a winter sports device, whereby a base structure (7) is produced from a continuously open-pored plastic material (8) with an initial thickness (10). At least one additive (13) is introduced into the pores (9) of the base structure (7). The base structure (7) together with the additive (13) is then reduced from its initial thickness (10) by am amount within a lower limit of 20% and an upper limit of 90% in a hot pressing operation. The invention further relates to a facing material (6) produced by the method and a winter sports device with such a facing material (6).

Abstract: In an airbag for a motor vehicle, with a flow passage via which two pressure chambers are connected to one another, a flow medium, in particular gas, flows from one pressure chamber through the flow passage into the other pressure chamber in a passage direction. To increase the suitability of the airbag for, for example, side impact loads, the flow passage includes a backflow safeguard that allows the flow medium to flow in the passage direction, whereas the flow of the flow medium in a blocking direction opposite to the passage direction is largely prevented.

Abstract: The power semiconductor element has an emitter region and a stop zone in front of the emitter region. The conductivities of the emitter region and of the stop zone are opposed to one another. In order to reduce not only the static but also the dynamic loss of the power semiconductor foreign atoms are used in the stop-zone. The foreign atoms have at least one energy level within the band gap of the semiconductor and at least 200 meV away from the conduction band and valence band of the semiconductor.

Abstract: The present invention refers to a method for inducing tumor apoptosis by influencing the ROS (reactive oxygen species) signaling pathway in tumor cells. Increasing the level of ROS leads to the selective inactivation of a tumor cell catalase and subsequently to an apoptosis of these cells. The level of ROS can be increased by increasing the level of nitric oxide through inhibition of the enzymes nitric oxide dioxygenase or arginase. According to the present invention inhibitors of the nitric oxide dioxygenase or arginase can be used for the manufacture of a medicament for the treatment of cancer. The present invention further provides a method for identifying compounds which can be used for the treatment of cancer, wherein the method allows to specifically identify compounds which induce apoptosis through the ROS signaling pathway. The present invention also provides a kit for identifying compounds which induce tumor apoptosis by inactivating a catalase on the tumor cell surface.

Abstract: A side impact protection device with a pelvic airbag module having a pelvic airbag which, in the inoperative state, is in a side part of a vehicle seat and, in the event of an impact of the vehicle, can be inflated and can be deployed through an outlet opening in the side part of the vehicle seat. In order to provide a side impact protection device constructed in a simple manner and produced cost-effectively, the outlet opening for the pelvic airbag in the side part of the vehicle seat is directed upward and forward with respect to the direction of travel of the vehicle.

Abstract: A medical care unit provides power supply or data transmission in medical apparatuses. In particular, current consumers and data transmission apparatuses are slidable along a coupling device of the medical care unit. The medical care unit includes an oblong support that includes the coupling device, which extend along the support and include at least two electrically insulated bus bars continuously extending in the coupling device. At least two bus bars are formed as power supply bus bars, at least one bus bar is formed as a data transmission bus bar, the coupling device as a hollow bar is formed with an opening along its longitudinal direction, and the power supply bus bars and the data transmission bus bars are arranged inside the hollow bar.