Abstract: Embodiments described herein provide techniques to enable the dynamic reconfiguration of memory on a general-purpose graphics processing unit. One embodiment described herein enables dynamic reconfiguration of cache memory bank assignments based on hardware statistics. One embodiment enables for virtual memory address translation using mixed four kilobyte and sixty-four kilobyte pages within the same page table hierarchy and under the same page directory. One embodiment provides for a graphics processor and associated heterogenous processing system having near and far regions of the same level of a cache hierarchy.

Abstract: An assembly and joining table, such as with weld splatter protection features, are disclosed along with systems and methods for operating the same in at least partially automated fashion. The table includes holders positioned about platform providing a work surface. Parts are placed within at least certain of the holders for joining to create an assembly. The holders include conductive surfaces and may include a sinuous recessed channels for wiring connecting the conductive surfaces to an electrical ground. A controller may operate motors of the table and command operations of robots for material handling and/or joining, such as based on data from a machine vision system viewing the table.

Abstract: Methods, systems, and computer programs are presented for creating a query template optimized for recall and precision to be used in database searches. One method includes operations for identifying a training set for training a model, generating subqueries based on features associated with the training set, and performing iterations to create a query template. Each iteration comprises performing a search for each subquery based on a disjunction of the subquery and the query template, calculating a precision of each subquery, and adding the subquery with the highest precision to the query template. The method further includes operations for receiving a search query from a device of a first user, customizing the query template based on the search query and information of the first user to obtain a search selection query, and performing a search utilizing the search selection query. The search results are presented on a display.

Abstract: The present invention relates to methods of designing kinase mutants for reprogramming the sensitivity of a target kinase to some specific inhibitors, methods of reprogramming the sensitivity of a target kinase to some specific inhibitors, wherein those kinase inhibitors have little or no affinity for the wild-type target kinase, vectors or cells expressing said mutated kinases, composition and uses thereof for the prevention and/or treatment of a disease or disorder, in particular cancer.

Abstract: A client device is provided with access to an electronic document using a user interface (UI) for a first application. The electronic document includes a reference to data associated with a second application. Upon detection of a first user interaction with a UI element associated with the reference to the data, the UI for the first application is updated to include, in the electronic document, at least a portion of the data associated with the second application. A request is received to modify data associated with the second application based on a second user interaction with the at least the portion of the data included in the electronic document. An instruction is transmitted to a computing system associated with the second application to modify the at least the portion of the data in accordance with the request.

Abstract: A spinal rod anchoring device is disclosed comprising a body comprising a distal end and a proximal end, wherein a threaded bone anchor is positioned toward the distal end, and a U-shaped head portion is positioned toward the proximal end. The head portion and the threaded bone anchor are fixedly attached. The spinal rod anchoring device also comprises a saddle comprising a concave interior region wherein the interior region has an open channel. The saddle is moveably seated within the base of the head portion, and a spinal connection element is disposed on the saddle. The spinal rod anchoring device further comprises a retaining pin configured to be inserted through the channel in the saddle and secured in a groove, wherein the groove is centrally positioned within the head portion, wherein the retaining pin secures the saddle to the head portion.

Abstract: Systems and methods for rearranging tags on a graphical user interface (GUI) based on known and unknown levels of web traffic are disclosed. To provide users with real estate listings that have popular home attributes with respect to a given region, the system uses known user interaction information to determine predicted user interaction information for real estate listing phrases (e.g., tags) that are associated with unknown user interaction information. The system then ranks the real estate listing phrases based on each real estate listing phrase's user interaction information. Based on the ranked real estate listing phrases, the system generates for display the highest ranked real estate listing phrase in association with a real estate listing being associated with the real estate listing phrase.

Abstract: A patient support includes a height adjustable patient support deck, at least one guard structure mounted for movement relative to the patient support deck, and a latch operable to lock the position of the guard structure in a raised position. The patient support further includes a CPR release operable to lower the head deck section of the patient support deck to place the patient support in an emergency state and further operable to release the latch to allow the guard rail structure to lower or be lowered from the raised position.

Abstract: Various implementations disclosed herein include systems, apparatuses, and methods to determine, for a category, a plurality of first values and a plurality of second values, wherein respective first values from the plurality of the first values and respective second values from the plurality of the second values are associated with respective permutations of parameters associated with the category, determine, based on the plurality of first values and the plurality of second values, a plurality of third values, determine, based on the plurality of third values, a minimum value and a maximum value, obtain, via a user interface, first data associated with the category, determine, based on the minimum value, the maximum value, and the first data, a scale factor, adjust, based on the scale factor, the plurality of third values to obtain a plurality of fourth values, and output the plurality of fourth values.

Abstract: The present disclosure provides PROTAC compounds represented by Formula (A): D-L-DSM (A), or an enantiomer, a diastereoisomer, and/or a pharmaceutically acceptable salt of any one of the foregoing, wherein: DSM is a degradation signaling compound {e.g., an E3 ubiquitin ligase recruitment ligand, such as a CRBN ligand or a VHL ligand) covalently attached to a linker L; L is a linker that covalently attaches DSM to D; and D is a Bcl-xL inhibitor compound of Formula (I) or Formula (II) covalently attached to the linker L: (I); (II) wherein the definitions for the variables are described herein. Also provided are pharmaceutical compositions comprising the PROTAC compounds of the present disclosure and methods of use and methods of making thereof.

Abstract: A system for cosmetic inspection of a test object is disclosed that includes a movable platform for receiving a test object. The movable platform is capable of positioning the test object within a dome. A plurality of cameras arranged oriented to capture different views of a plurality of surfaces of the test object. A plurality lights arranged are outside the dome, the plurality of lights selectively enabled or disabled according to which of the plurality of surfaces of the test object is to be captured.

Abstract: Processes for conversion of propylene polyol feed into useful petrochemical products, including olefin monomers, are described. Such processes comprise: adding a feed stream comprising one or more propylene polyols, hydrogen, and optionally water, to a catalytic conversion reaction zone in the presence of a first solid acid catalyst component and a hydrogenation catalyst component and reacting at a pressure and temperature sufficient to form a first product stream comprising a propanol component. The first product stream can be added to a dehydration reaction zone in the presence of a dehydration catalyst and reacted at a pressure and temperature sufficient to form a second product stream comprising propylene.

Abstract: The present disclosure provides a generative modeling framework for generating highly realistic and privacy preserving synthetic records for heterogenous time-series data, such as electronic health record data, financial data, etc. The generative modeling framework is based on a two-stage model that includes sequential encoder-decoder networks and generative adversarial networks (GANs).

Abstract: The present disclosure relates to the fields of a method a kit for molecular diagnostics and genomics. More particularly, this disclosure relates to a method and a kit fir detecting a DNA fragment joining event or distinguishing an alternative splicing event. The present disclosure also relates to a method for administering a subject with proper treatment by steps of determining the risk of a particular cancer type or genotype.

Abstract: A system and method employ vibration sensors on board a vehicle to effectively identify and implement voice commands. The vibration sensors provide vibration signals corresponding to the speech of vehicle occupants to a controller. The controller may verify the content of the voice commands and identify a speaker of the voice commands with the vibration signals. The voice command may be implemented by operating a controlled device in a specific passenger zone of the vehicle. In some implementations, the speech of a specific occupant may be designated as voice commands to be transmitted over a videoconference or voice call and the speech of surrounding vehicle occupants may be designated as noise to be excluded from transmission. Further, driver voice commands may be given priority when conflicting commands are given by other vehicle passengers.

Abstract: Devices and methods for restricting the flow of blood through tissue of a human face, such as for the treatment of epistaxis, which include an insertion body configured for insertion into a human mouth; an external body configured for placement against an outer surface of the human mouth; and a structure configured to reversibly position the insertion body and external body towards and away from one another.

Abstract: A substrate processing method including: providing a substrate containing an etch mask over a metallic molybdenum layer in a recessed feature; exposing the substrate to a plasma-excited deposition gas that forms an etch protection layer on a sidewall of the recessed feature; and exposing the substrate to a plasma-excited etching gas that etches the metallic molybdenum layer according to the etch mask, where the exposing steps are alternatingly performed a plurality of times.

Abstract: An article for use as part of a non-combustible aerosol provision system, wherein the article includes at least one aerosol outlet and at least one airflow channel, wherein the at least one aerosol outlet is arranged in fluid communication with the at least one airflow channel, wherein the at least one airflow channel has a longitudinal section and a lateral section connected together via a joint section, wherein the joint section has a curved outer wall.

Abstract: Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

Abstract: Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors.