Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: Methods and compositions to controllably regulate cells at a target site. A quantum dot-targeting agent complex is administered to a patient in need of therapy, and the complex is stimulated using an implanted fiber optic system. In embodiments, the system includes an electrical sensor that detects and monitors electrical activity of the stimulated controllably regulated cells, and relays this information to a controller that can regulate further stimulation.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: A vitreous cutter sleeve is disclosed herein. The vitreous cutter sleeve includes an elongate tubular body with a peripheral sidewall and a central passageway disposed through the elongate tubular body, the central passageway of the elongate tubular body configured to receive a vitreous cutter therein, at least a portion of the elongate tubular body being formed from a material that is transparent to visible light, the material being further configured to conduct at least one of infrared radiation, radiofrequency radiation, and an electrical current; and an illumination device operatively coupled to the elongate tubular body such that the illumination device is capable of providing illumination to an inside portion of an eye through at least a portion of the peripheral sidewall of the elongate tubular body. A vitreous cutter system that includes a vitreous cutter and a vitreous cutter sleeve is also disclosed herein.

Abstract: An integral laser imaging and coagulation apparatus, and associated systems and methods that allow a physician (e.g., a surgeon) to perform laser surgical procedures on an eye structure or a body surface with an integral laser imaging and coagulation apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. In some embodiments, communication between the integral laser imaging and coagulation apparatus and control system is achieved via the Internet®.

Abstract: Methods and compositions to controllably regulate cells at a target site. A quantum dot-targeting agent complex is administered to a patient in need of therapy, and the complex is stimulated using an implanted fiber optic system. In embodiments, the system includes an electrical sensor that detects and monitors electrical activity of the stimulated controllably regulated cells, and relays this information to a controller that can regulate further stimulation.

Abstract: A fundus camera includes three fluidic lenses, each fluidic lens having a chamber configured so as to capable of having a fluid inserted therein or removed therefrom, such that the shape of each of the three fluidic lenses is capable of being changed based on an amount of fluid therein, a refractive or diffractic telescopic system, a Shack-Hartmann sensor configured to automatically control of the amount of the fluid in the chamber of each of the three fluidic lenses, so as to be capable of correcting refractive errors in an eye, and a multifunction camera configured for precision of fundus photography.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: A vitrectomy or needle made of a hard resistance metal glass alloy. The wall of the outer tubing or the entire needle can be illuminated when connected to a light source. The instrument, when inserted inside the tissue or the eye, provides illumination, thereby illuminating the surrounding tissue structure and eliminating the need for additional internal or external illumination.

Abstract: An automated camera system is disclosed herein. The automated camera system includes a camera configured to capture an image of an object; at least one fluidic lens disposed between the camera and the object, the at least one fluidic lens having a chamber that receives a fluid therein; a fluid control system operatively coupled to the at least one fluidic lens, the fluid control system configured to insert, or remove, an amount of the fluid into, or from, the chamber of the at least one fluidic lens; and a Shack-Hartmann sensor assembly operatively coupled to the fluid control system, the Shack-Hartmann sensor assembly by means of the fluid control system configured to automatically control the amount of the fluid in the chamber of the at least one fluidic lens, thereby automatically focusing the camera so that the image captured of the object is in focus.

Abstract: Methods and compositions to controllably regulate cells at a target site. A quantum dot-targeting agent complex is administered to a patient in need of therapy, and the complex is stimulated using an implanted fiber optic system. In embodiments, the system includes an electrical sensor that detects and monitors electrical activity of the stimulated controllably regulated cells, and relays this information to a controller that can regulate further stimulation.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells. In one embodiment, the method is administered in combination with localized internal ionizing radiation therapy.

Abstract: An integral laser imaging and coagulation apparatus, and associated systems and methods that allow an ophthalmologist to perform laser retinal surgical procedures with an integral laser imaging and coagulation apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. In some embodiments, communication between the integral laser imaging and coagulation apparatus and control system is achieved via the Internet®.

Abstract: Methods and compositions to controllably regulate cells at a target site. A quantum dot-targeting agent complex is administered to a patient in need of therapy, and the complex is stimulated using an implanted fiber optic system. In embodiments, the system includes an electrical sensor that detects and monitors electrical activity of the stimulated controllably regulated cells, and relays this information to a controller that can regulate further stimulation.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.

Abstract: A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles.

Abstract: A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles. The heat (temperature) and photoacoustic sound wave production inside the target tissue is measured. The desired temperature is achieved using a laser and photoacoustic imaging technique. Hyperthermia treatment of tissue applies a heat source to kill cells without protein denaturation. The hyperthermia treatment may further comprise platelet-derived treatment. The method introduces an encapsulated dye that is released at a selected temperature in the target site to indicate that a threshold temperature has been reached to hyperthermally treat the tissue. The temperature to which the target site is treated ranges from about 39° C. to about 58° C., and may last from about 5 seconds to about 30 minutes. The composition which can be a liposome composition encapsulating the dye can be introduced to the bloodstream to flow through the target site.

Abstract: A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells. In one embodiment, the method provides a synergetic effect with chemotherapy.