Patents by Inventor Graham Holmwood

Graham Holmwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4672134
    Abstract: Oxiranes of the formula: ##STR1## in which R is ##STR2## R.sup.1 is hydrogen or halogen, R.sup.2 is halogen,R.sup.3 is alkyl with 1 to 4 carbon atoms or alkoxy with 1 to 4 carbon atoms,n is 0, 1 or 2,Y.sup.1 and Y.sup.2 each independently is hydrogen or alkyl with 1 to 4 carbon atoms,Z is halogen or alkyl with 1 to 4 carbon atoms, andm is 0 or 1.and useful as intermediates in the preparation of fungicides.
    Type: Grant
    Filed: June 14, 1985
    Date of Patent: June 9, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Jorg Stetter, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes, Hans Scheinpflug
  • Patent number: 4668660
    Abstract: The invention relates to hydroxyethylazolyl derivatives, defined herein by formula (I) and particularly to the use of said derivatives for the treatment of viral infections.
    Type: Grant
    Filed: April 10, 1984
    Date of Patent: May 26, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Arnold Paessens, Gert Streissle, Manfred Plempel, Karl H. B/u/ chel, Hans-Ludwig Elbe, Graham Holmwood, Udo Kraatz, Erik Regel
  • Patent number: 4652579
    Abstract: The invention relates to 1-hydroxylethyl-azole derivatives of formula (I) in composition form and includes the use of such compositions as antimicrobial agents.
    Type: Grant
    Filed: October 19, 1984
    Date of Patent: March 24, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Karl H. Buchel, Manfred Plempel, Ingo Haller
  • Patent number: 4645767
    Abstract: Hydroxyethyl-azole derivatives of the formula ##STR1## in which R.sup.1 represents alkyl or the grouping Ar--Y--,Ar represents optionally substituted aryl,X represents a nitrogen atom or the CH group,Y represents a direct bond or the grouping --CH.sub.2 --, --CH.sub.2 CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 --, --CH.dbd.CH-- or --C.tbd.C--,Z represents oxygen or the NOR.sup.2 group andR.sup.2 represents hydrogen, alkyl, alkenyl, alkinyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl,or addition products thereof with acids or metal salts, which possess fungicidal activity.
    Type: Grant
    Filed: September 14, 1984
    Date of Patent: February 24, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Wolfgang Kramer, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes
  • Patent number: 4639462
    Abstract: Heterocyclyl-hydroxyalkyl-azolyl derivatives of the formula ##STR1## in which Az represents 1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or imidazol-1-yl,Het represents optionally substituted dioxolanyl or 1,3-dioxanyl,R represents alkyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalky, optionally substituted phenylthioalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, alkenyl, optionally substituted phenylalkenyl, optionally substituted cyclohexylalkenyl, furyl, naphthyloxymethyl or azolylalkyl,R' represents hydrogen, optionally substituted alkyl or alkenyl andn represents the number 0 or 1,or addition products thereof with acids or metal salts, which possess fungicidal activity.
    Type: Grant
    Filed: November 1, 1983
    Date of Patent: January 27, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Graham Holmwood, Erik Regel, Paul Reinecke, Wilhelm Brandes
  • Patent number: 4632932
    Abstract: The invention concerns the provision of compound of Formula I as defined herein as well as compositions containing compound of Formula I. Said compounds and compositions are used as antimycotic agents and the invention includes such use.
    Type: Grant
    Filed: November 8, 1983
    Date of Patent: December 30, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Graham Holmwood, Erik Regel, Manfred Plempel
  • Patent number: 4626595
    Abstract: According to the present invention 1-hydroxyethyl azole compounds are provided for in a process characterized by reacting an oxirane of the general formula ##STR1## in which R represents an alkyl radical, an optionally substituted cycloalkyl radical or an optionally substituted phenyl radical,Y represents a grouping --OCH.sub.2 --, --CH.sub.2 CH.sub.2 -- or --CH.dbd.CH--,Z represents a halogen atom, an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halogenoalkylthio radical, an optionally substituted phenyl radical, an optionally substituted phenoxy radical, an optionally substituted phenylalkyl radical or an optionally substituted phenylalkoxy radical andm is 0, 1, 2 or 3,with an azole of the general formula ##STR2## in which X represents a nitrogen atom or a CH group.
    Type: Grant
    Filed: January 28, 1985
    Date of Patent: December 2, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Karl H. Buchel, Klaus Lurssen, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4623653
    Abstract: Synergistic fungicidal compositions comprising(i) a substituted 1-hydroxyethyl-triazole of the formula ##STR1## in which R.sup.1, R.sup.2, X, Y and A have various meanings, or addition products thereof with acids or metal salts, and(ii) at least one of(A) wettable sulphur,(B) a polyhalogenoalkylthio derivative,(C) a quanidine derivative,(D) an aromatic acid lactone,(E) a dithiocarbamate,(F) a benzimidazole derivative,(G) an imidazole or triazole derivative,(H) a phosphoric acid ester,(I) a tetrahydroquinoline derivative,(J) an S, N-heterocyclic compound,(K) a urea derivative,(L) a sulphonamide derivative,(M) a polyhydroxyether derivative,(N) a triazine derivative,(O) a copper-hydroxy quinoline complex,(P) an N-formul derivative,(Q) a morpholine derivative,(R) a quinoxaline derivative, and(S) a dicarboxamide derivative.
    Type: Grant
    Filed: August 27, 1984
    Date of Patent: November 18, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilhelm Brandes, Gerd Hanssler, Paul Reinecke, Hans Scheinpflug, Graham Holmwood
  • Patent number: 4622335
    Abstract: Fungicidally active novel hydroxyethylazolyl-oxime derivatives of the formula ##STR1## in which Ar is optionally substituted aryl,R.sup.1 is hydrogen or alkyl,R.sup.2 is hydrogen, alkyl, alkenyl, alkinyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl, andX is a nitrogen atom or the CH group,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: September 11, 1984
    Date of Patent: November 11, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Graham Holmwood, Paul Reinecke, Wilhelm Brandes
  • Patent number: 4596815
    Abstract: Azolylmethyl-thienyl-carbinols of the formula ##STR1## in which R.sup.1 is optionally substituted phenyl, andR.sup.2 is optionally substituted thienyl,or addition products thereof with acids or metal salts, which possess fungicidal activity.
    Type: Grant
    Filed: May 29, 1984
    Date of Patent: June 24, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Udo Kraatz, Graham Holmwood, Karl H. Buchel, Hans-Jurgen Rosslenbroich, Hans Scheinpflug
  • Patent number: 4584373
    Abstract: Combating fungi and/or regulating the growth of plants with novel aroxy-pyrimidinyl-alkanols of the formula ##STR1## in which R is optionally substituted naphthyl, or ##STR2## Y each independently is halogen, alkyl, cycloalkyl, alkoxy, halogenoalkyl, halogenoalkoxy, alkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkoxy or optionally substituted phenylalkyl,or addition products thereof with acids or metal salts.
    Type: Grant
    Filed: July 2, 1984
    Date of Patent: April 22, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Klaus Lurssen, Paul Reinecke, Wilhelm Brandes, Gerd Hanssler
  • Patent number: 4564622
    Abstract: The invention relates to 2-(4-chlorophenoxymethyl)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanol and its use for treating herpes viral infections.
    Type: Grant
    Filed: April 29, 1985
    Date of Patent: January 14, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gert Streissle, Manfred Plempel, Arnold Paessens, Graham Holmwood, Karl H. Buchel
  • Patent number: 4548945
    Abstract: Substituted 1-hydroxyethyl-triazole derivatives of the formula ##STR1## in which R represents optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl,X represents the grouping --OCH.sub.2 --, --SCH.sub.2 --, --(CH.sub.2)p-- or --CH.dbd.CH--,Y represents the grouping --CO--Y.sup.1 or an acetal or ketal derivative thereof, or the grouping --C(Y.sup.1).dbd.N--OY.sup.2,Y.sup.1 represents hydrogen, alkyl, alkenyl, alkinyl, optionally substituted cycloalkyl, optionally substituted phenyl or optionally substituted benzyl,Y.sup.2 represents hydrogen, alkyl, alkenyl, alkinyl, optionally substituted cycloalkyl or optionally substituted benzyl,Z represents halogen, alkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halogenoalkylthio andthe indices m and p represent 0, 1 or 2,or addition products thereof with acids or metal salts which possess fungicidal activity.
    Type: Grant
    Filed: September 21, 1983
    Date of Patent: October 22, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Jorg Stetter, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes, Hans Scheinpflug
  • Patent number: 4532341
    Abstract: Oxirane compounds of the formula ##STR1## in which R represents tert-butyl, iso-propyl radical, cyclopropyl, substituted cyclopropyl, cyclopentyl or substituted cyclopentyl, cyclohexyl or substituted cyclohexyl, in each case the substituent being selected from methyl, or phenyl which is optionally mono or di-substituted by identical or different substituents selected from fluorine, chlorine, methyl and trifluoromethyl,Y represents a grouping --OCH.sub.
    Type: Grant
    Filed: June 6, 1983
    Date of Patent: July 30, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Karl H. Buchel, Klaus Lurssen, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4525204
    Abstract: Pyrimidine-butanol derivatives of the general formula ##STR1## in which X represents hydrogen, halogen, alkyl or alkoxy, or represents benzyloxy which is optionally substituted by halogen andY represents hydrogen or halogenhave powerful growth-regulating properties.
    Type: Grant
    Filed: October 24, 1980
    Date of Patent: June 25, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Klaus Lurssen
  • Patent number: 4518600
    Abstract: 1-Phenoxy-2-pyridinyl(pyrimidinyl)-alkanols of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl,X represents a nitrogen atom or the CH group,Y represents halogen, alkyl, cycloalkyl, alkoxy, halogenoalkyl, alkylthio, or an optionally substituted phenyl, phenoxy, phenylalkoxy or phenylalkyl radical, andn represents 0 or an integer from 1 to 5, the Y's being selected independently of one another when n is 2, 3, 4 or 5,in the form of the free base, a salt or a metal salt complex thereof, which possess fungicidal properties.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: May 21, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Paul-Ernst Frohberger, Wilhelm Brandes, Volker Paul
  • Patent number: 4515617
    Abstract: A benzyl-pyrimidinylalkyl-ether of the formula ##STR1## in which R is alkyl, optionally substituted cycloalkyl or optionally substituted phenyl, andX.sup.1, X.sup.2 and X.sup.3 each independently is hydrogen, halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, cyano, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy,or an acid addition salt or metal salt complex thereof, which possesses fungicidal and plant growth-regulating properties. The corresponding pyrimidinyl-carbinols are also new.
    Type: Grant
    Filed: August 2, 1983
    Date of Patent: May 7, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Klaus Lurssen, Paul-Ernst Frohberger
  • Patent number: 4499281
    Abstract: A substituted triazolylmethyl-oxirane of the formula ##STR1## in which R is optionally substituted alkyl, aryl or cycloalkyl is prepared by reacting a triazolyl-ketone of the formula ##STR2## with (a) dimethyloxosulphonium methylide of the formula ##STR3## or (b) trimethylsulphonium methylsulphate of the formula[(CH.sub.3).sub.3 S].sup..sym. CH.sub.3 SO.sub.4.sup..crclbar.in the presence of a diluent.The end product can then be reacted with a phenol of the formulaR"--OHto produce known fungicidally active compounds of the formula ##STR4## in which R" is optionally substituted phenyl.
    Type: Grant
    Filed: February 26, 1982
    Date of Patent: February 12, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Erik Regel
  • Patent number: 4452625
    Abstract: A plant growth-inhibiting composition comprising ##STR1## wherein the various radicals are as defined.
    Type: Grant
    Filed: January 7, 1982
    Date of Patent: June 5, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Lurssen, Graham Holmwood, Wolfgang Kramer, Erik Regel, Wolf Reiser, Rolf Schroder
  • Patent number: 4438122
    Abstract: 1-Phenoxy-2-pyridinyl(pyrimidinyl)-alkanols of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl,X represents a nitrogen atom or the CH group,Y represents halogen, alkyl, cycloalkyl, alkoxy, halogenoalkyl, alkylthio, or an optionally substituted phenyl, phenoxy, phenylalkoxy or phenylalkyl radical, andn represents 0 or an integer from 1 to 5, the Y's being selected independently of one another when n is 2, 3, 4 or 5,in the form of the free base, a salt or a metal salt complex thereof, which possess fungicidal properties.
    Type: Grant
    Filed: June 24, 1982
    Date of Patent: March 20, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Paul-Ernst Frohberger, Wilhelm Brandes, Volker Paul