Patents by Inventor Gregory M. Lanza

Gregory M. Lanza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrug compositions, prodrug nanoparticles, and methods of use thereof
    Patent number: 11872313
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: January 16, 2024
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • Prodrug compositions, prodrug nanoparticles, and methods of use thereof
    Patent number: 11141379
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: October 12, 2021
    Assignee: Washington University
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • Homing agents
    Patent number: 11052163
    Abstract: The present disclosure provides peptide constructs for diagnostic imaging and therapeutic applications, using pegylated peptides which exhibit specific binding for a target molecule of interest, such as a biomarker of a disease or disorder.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: July 6, 2021
    Assignee: Washington University
    Inventors: Gregory M. Lanza, Samuel I. Achilefu, Grace Hufang Cui
  • PRODRUG COMPOSITIONS, PRODRUG NANOPARTICLES, AND METHODS OF USE THEREOF
    Publication number: 20210077400
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Application
    Filed: November 5, 2020
    Publication date: March 18, 2021
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • PRODRUG COMPOSITIONS, PRODRUG NANOPARTICLES, AND METHODS OF USE THEREOF
    Publication number: 20190192436
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • Prodrug compositions, prodrug nanoparticles, and methods of use thereof
    Patent number: 10201500
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: February 12, 2019
    Assignee: Washington University
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • HOMING AGENTS
    Publication number: 20180021462
    Abstract: The present disclosure provides peptide constructs for diagnostic imaging and therapeutic applications, using pegylated peptides which exhibit specific binding for a target molecule of interest, such as a biomarker of a disease or disorder.
    Type: Application
    Filed: September 21, 2017
    Publication date: January 25, 2018
    Applicant: Washington University
    Inventors: Gregory M. Lanza, Samuel A. Achilefu, Grace Hufang Cui
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20170367323
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: August 15, 2017
    Publication date: December 28, 2017
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Homing agents
    Patent number: 9849201
    Abstract: The present disclosure provides peptide constructs for diagnostic imaging and therapeutic applications, using pegylated peptides which exhibit specific binding for a target molecule of interest, such as a biomarker of a disease or disorder.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: December 26, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M Lanza, Samuel A. Achilefu, Grace Hufang Cui
  • Blood substitute composition and method of use
    Patent number: 9750241
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: September 5, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20170181424
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: March 16, 2017
    Publication date: June 29, 2017
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Blood substitute composition and method of use
    Patent number: 9655952
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: May 23, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20160346358
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: August 9, 2016
    Publication date: December 1, 2016
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Prodrug compositions, prodrug nanoparticles, and methods of use thereof
    Patent number: 9498439
    Abstract: Nanoparticles comprising a prodrug and prodrugs linked to phospholipids, wherein the linkages facilitate release of the prodrugs from the nanoparticles to sites within a target cell or cell membrane by fusion of the particle and the cell membrane are disclosed. Also disclosed are methods for producing and using the nanoparticles and their constituents.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: November 22, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • METHODS FOR IMPROVING MUSCLE STRENGTH
    Publication number: 20160324835
    Abstract: The present invention relates to methods for improving muscle strength and treating muscular dystrophy.
    Type: Application
    Filed: July 18, 2016
    Publication date: November 10, 2016
    Inventors: Samuel A. Wickline, Gregory M. Lanza
  • Blood substitute composition and method of use
    Patent number: 9486508
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: November 8, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
    Patent number: 9468607
    Abstract: The present invention provides nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to deliver therapeutic agents and/or imaging agents.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: October 18, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Samuel A. Wickline, Dipanjan Pan
  • PRODRUG COMPOSITIONS, PRODRUG NANOPARTICLES, AND METHODS OF USE THEREOF
    Publication number: 20160279060
    Abstract: The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
    Type: Application
    Filed: June 10, 2016
    Publication date: September 29, 2016
    Inventors: Gregory M. Lanza, Dipanjan Pan
  • Particles for imaging
    Patent number: 9446150
    Abstract: The invention encompasses particles comprising metal atoms, methods of making the particles, and methods for using the particles. In particular, the particles may be used to image biological tissues or to deliver a bioactive agent.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: September 20, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Samuel A. Wickline, Dipanjan Pan, Angana Senpan
  • Methods for improving muscle strength
    Patent number: 9415018
    Abstract: The present invention relates to methods for improving muscle strength and treating muscular dystrophy.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: August 16, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Samuel A. Wickline, Gregory M. Lanza