Abstract: Disclosed are a full-automatic high-pressure spray cleaning and rust prevention device and an application method thereof. The device comprises a cleaning platform, a center rod and a swingable clamp module; the center rod is arranged on the cleaning platform, and an upper end is fixedly provided with the swingable clamp module; the swingable clamp module comprises a worm gear and worm assembly and a clamp, and the worm gear and worm assembly is capable of driving the clamp to deflect up and down; a driving mechanism arranged in a bottom portion of the cleaning platform is in driving connection with the center rod, so that the center rod is capable of driving the swingable clamp module to realize vertical lifting motion and rotary station switching; and the cleaning platform is sequentially provided with a positioning and spraying area, an air-drying area and a rust prevention area around the center rod.

Abstract: A memory device includes a plurality of input/output (I/O) nodes, a circuit, a latch, a memory, and control logic. The plurality of I/O nodes receive a predefined data pattern. The circuit adjusts a delay for each I/O node as the predefined data pattern is received. The latch latches the data received on each I/O node. The memory stores the latched data. The control logic compares the stored latched data to an expected data pattern and sets the delay for each I/O node based on the comparison.

Abstract: This application provides a data transmission method. The method includes: An electronic device first establishes an MPTCP connection to an application server, where the MPTCP connection includes two TCP connections. Then, the electronic device receives indication information from an application server, where the indication information includes a type identifier and a parameter. When the type identifier indicates a low data transmission delay requirement, the electronic device receives, in a first time period after the electronic device receives the indication information, the data stream by using a first TCP connection. When an accumulated data amount actually received by the electronic device in the first time period is less than a product of the parameter and duration corresponding to the first time period, the electronic device receives the data stream in a second time period by using both the two TCP connections.

Abstract: A computer-implemented method of determining effects of drug combinations on treatment outcomes. A plurality of genomic and clinical variables are generated from the combination of comprehensive genomic data, EHR data, and clinical treatment data. Based on Cox Proportional Hazards model, independent risk factors, cumulative hazard-ratios, and p-values for the combination of a first drug and a second drug (or a biomarker) are calculated to determine the nature of the combination of the first drug and the second drug (or the biomarker) with respect to treating the disease.

Abstract: The present disclosure relates to a medicament for treating cholangiocarcinoma with KRAS mutations. Specifically, the present invention relates to a method of ER inhibitors for the specific treatment of cholangiocarcinoma with KRAS mutations, and to a use of ER inhibitors in the preparation of a medicament for the treatment of cholangiocarcinoma with KRAS mutations. New therapeutic regimens for patients suffering from cholangiocarcinoma with KRAS mutations are provided to improve the possibility of therapeutic benefit for patients.

Abstract: A method of instance segmentation, comprising, defining a bounding box, depth mapping the bounding box, sorting the depth map, estimating stability due to noise of the sorted depth map, detecting low frequency jumps of the sorted depth map based on the estimated stability, detecting high frequency jumps of the sorted depth map, comparing the detected low frequency jumps and the detected high frequency jumps, detecting at least one of a largest object and a closest object based on the comparison and pixel masking the at least one of the largest object and the closest object.

Abstract: A system implements a cloud-based digital platform allows developers to build new applications/services and then deploy to cloud platforms among continuous deployment, A/B test, blue/green deployment, and canary deployment. The system configures a service mesh on top of a cluster of computers. The system initializes a new service via templates that include common libraries, security scan pipeline, monitoring as code pipeline, and code coverage management for internal policy compliances, as well automated cloud resources request and provisioning. One or more proxy services, that extract data from the data sources using filters, can be executed. The system may use machine learning based models that are trained using the data extracted by the proxy service. The system allows automatic provisioning, computation orchestration, storage requests, and artificial intelligence insight feedback, as well as automated self-services to navigate complex systems and reduce on-boarding times of the platform.

Abstract: The present invention discloses a method for predicting fracture height during fracturing stimulation in multi-layer formation, comprising specific steps of: (1) acquiring basic parameters; (2) calculating a displacement discontinuity quantity of an artificial fracture; (3) calculating induced stress generated by the fracture; (4) calculating stress intensity factors at a fracture tip without considering a fracture tip plasticity; (5) calculating sizes of a plastic zone; (6) calculating stress intensity factors at the fracture tip considering the plastic zone; and (7) judging a relationship between the stress intensity factors and a fracture toughness. The present invention is suitable for multiple stratums, and the influences of parameters of tip plasticity, induced stress, crustal stress, and rock mechanics are considered so that a calculation result is more accurate and calculation efficiency is higher.

Abstract: A memory device including a memory array operatively coupled to an array data bus and a deserializer circuit operatively coupled with the array data bus. The deserializer circuit includes a first ring counter including a first set of flip-flops to sequentially output a set of rising edge clock signals based on a reference clock input and a second ring counter portion including a second set of flip-flop circuits to sequentially output a set of falling edge clock signals based on the reference clock input. A rising data circuit portion of the deserializer circuit includes a set of flip-flops that each receive a rising data portion from a respective latch circuit in response to a rising edge clock signal. A falling data circuit portion of the deserializer circuit includes a set of flip-flops that each receive a falling data portion from a respective latch circuit in response to a falling edge clock signal.

Abstract: A memory device including a memory array operatively coupled to an array data bus and a deserializer circuit operatively coupled with the array data bus. The deserializer circuit includes a first ring counter including a first set of flip-flops to sequentially output a set of rising edge clock signals based on a reference clock input and a second ring counter portion including a second set of flip-flop circuits to sequentially output a set of falling edge clock signals based on the reference clock input. A rising data circuit portion of the deserializer circuit includes a set of flip-flops that each receive a rising data portion from a respective latch circuit in response to a rising edge clock signal. A falling data circuit portion of the deserializer circuit includes a set of flip-flops that each receive a falling data portion from a respective latch circuit in response to a falling edge clock signal.

Abstract: An electrical circuit device includes a signal bus comprising a plurality of parallel signal paths and a calibration circuit, operatively coupled with the signal bus. The calibration circuit can perform operations including determining a representative duty cycle for a plurality of signals transferred via the plurality of parallel signal paths, the plurality of signals comprising a plurality of duty cycles and comparing the representative duty cycle for the plurality of signals transferred via the plurality of parallel signal paths to a reference value to determine a comparison result. The calibration circuit can perform further operations including adjusting, based on the comparison result, a trim value associated with the plurality of duty cycles of the plurality of signals to compensate for distortion in the plurality of duty cycles and calibrating the plurality of duty cycles of the plurality of signals using the adjusted trim value.

Abstract: A method of mapping and localization is disclosed that includes, reconstructing a point cloud and a camera pose based on VSLAM, synchronizing the camera pose and a GPS timestamp at a first set of GPS coordinate points and transforming the first set of GPS coordinate points corresponding to the GPS timestamp into a first set of ECEF coordinate points. The method also includes determining a translation and a rotation between the camera pose and the first set of ECEF coordinate points, transforming the point cloud and the camera pose into a second set of ECEF coordinates based on the translation and the rotation and transforming the point cloud and the camera pose into a second set of GPS coordinate points. The method further includes constructing and storing a key-frame image, a key-frame timestamp and a key-frame GPS based on the second set of GPS coordinate points.

Abstract: The present disclosure provides a group of diagnostic biomarkers usable for diagnosis of colorectal cancer or colorectal adenoma. A method for detecting colorectal cancer or colorectal adenoma using the group of diagnostic biomarkers is also provided. For example, the method provided by the present disclosure is a non-invasive approach that may utilize serum samples for detecting colorectal cancer. Moreover, the method for detecting colorectal cancer may detect colorectal cancer of different stages (e.g., pre-cancer stage, early stage, middle stage, late stage).

Abstract: An electrical circuit device includes a signal bus comprising a plurality of parallel signal paths and a calibration circuit, operatively coupled with the signal bus. The calibration circuit can perform operations including determining a representative duty cycle for a plurality of signals transferred via the plurality of parallel signal paths, the plurality of signals comprising a plurality of duty cycles and comparing the representative duty cycle for the plurality of signals transferred via the plurality of parallel signal paths to a reference value to determine a comparison result. The calibration circuit can perform further operations including adjusting, based on the comparison result, a trim value associated with the plurality of duty cycles of the plurality of signals to compensate for distortion in the plurality of duty cycles and calibrating the plurality of duty cycles of the plurality of signals using the adjusted trim value.

Abstract: A method of instance segmentation, comprising, defining a bounding box, depth mapping the bounding box, sorting the depth map, estimating stability due to noise of the sorted depth map, detecting low frequency jumps of the sorted depth map based on the estimated stability, detecting high frequency jumps of the sorted depth map, comparing the detected low frequency jumps and the detected high frequency jumps, detecting at least one of a largest object and a closest object based on the comparison and pixel masking the at least one of the largest object and the closest object.

Abstract: A method of camera localization, comprising, receiving a camera image, receiving a LiDAR point cloud, estimating an initial camera pose for the camera image, sampling an initial set of depth projections within the LiDAR point cloud, measuring a similarity of the initial camera pose to the initial set of depth projections and deriving a subsequent set of depth projections based on the measured similarity.

Abstract: An invisible orthodontic device without an occlusal surface includes a medial surface and a lateral surface. The medial surface is a side surface adjacent to the tongue, and the lateral surface is a side surface adjacent to the cheek. One end of each of the medial surface and the lateral surface is connected through a top face, and other ends thereof are in an open state and include a wearing hole. Lateral sides of the medial surface and the lateral surface are connected through a connection face. The medial surface, the lateral surface, the top face and the connection face enclose to form an accommodation groove in the middle for accommodating teeth. The wearing hole is in communication with the accommodation groove, and the invisible orthodontic device can be worn on the teeth through the wearing hole. The invisible orthodontic device includes an anterior region and a molar region.

Abstract: Related are a JAK kinase inhibitor, a preparation method for same, and applications thereof in the field of medicine, related to the field of medicinal chemistry. Provided is a novel small molecule JAK inhibitor, which has the structure as represented by formula (II). The compound provides improved efficacy and safeness in preventing or treating a JAK-related indication.

Abstract: Systems and methods for a hybrid system-on-chip usable for predicting performance and power requirements of a host server include a big cores module, including central processing units, for receiving and pre-processing performance and power metrics data of the host server and to allocate computing resources, a small cores module, including massively parallel processing units, for mapping each instance associated with host server in the performance and power metrics data to a corresponding massively parallel processing unit based on the allocated computing resources for a per-instance metrics calculation, and an artificial intelligence (AI) accelerator for calculating performance and power prediction results based on the per-instance calculations from the small cores module.