Abstract: The present disclosure discloses a fan blade structure, a fan and a fan lamp, belonging to the field of household appliances. A fan blade structure includes: an inner edge located at a windward side, where the inner edge at least partially protrudes towards a leeward side, and the inner edge extends obliquely upwards, gradually, from one end of the fan blade structure close to a rotational axis to one end of the fan blade structure facing away from the rotational axis; an outer edge located at the leeward side, where the outer edge protrudes towards the leeward side, and the outer edge extends obliquely upwards from the end of the fan blade structure close to the rotational axis to the end of the fan blade structure facing away from the rotational axis; and a cambered surface connected between the inner edge and the outer edge.

Abstract: The present disclosure provides a fan lamp, which includes: a mounting base, a suspension rod, a fan assembly, and a lamp assembly, the mounting base is fixedly installed on an installation foundation, the suspension rod is connected with the fan assembly, the fan assembly includes a motor with a fixed shaft, the suspension rod is fixedly connected with the fixed shaft of the motor through at least one connecting piece, and the suspension rod is connected with an end portion of the fixed shaft in a sleeved manner, one of the suspension rod and the fixed shaft that is arranged inside includes at least one first through-hole that penetrates a main body, and the other one of the suspension rod and the fixed shaft that is arranged outside includes at least one pair of a second through-hole and a threaded hole that are arranged on a straight line.

Abstract: Disclosed are a pyrrolidine compound as represented by formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and the use of the pharmaceutical composition as a selective estrogen receptor degrader (SERD) in the prevention or treatment of estrogen receptor-related diseases.

Abstract: The disclosure discloses a fan lamp, including a lamp panel, a lamp assembly, a fan assembly, and a motor assembly. The lamp assembly is provided on a side of the lamp panel; the fan assembly is provided on a side of the lamp panel away from the lamp assembly; and the motor assembly includes a direct current motor, and the fan assembly is configured to rotate under the driving of the direct current motor.

Abstract: A ceiling lamp and a chassis are provided. The ceiling lamp includes a chassis and a light source module; the chassis includes a surrounding wall and a partition disposed within the surrounding wall, the partition divides a region surrounded by the surrounding wall into an assembly recess with a downward opening and a wiring recess with an upward opening; part of the partition protrudes upwardly into the wiring recess and forms a light source recess with a downward opening and an upward recess bottom, and the light source module is provided in the light source recess. The chassis includes a surrounding wall and a partition disposed within the surrounding wall, the partition divides a region surrounded by the surrounding wall into an assembly recess with a downward opening and a wiring recess with an upwardly opening.

Abstract: The present application describes a substituted aryl compound used as an RAD51 inhibitor and a pharmaceutically acceptable salt thereof. The compound has the structure as represented by Formula (I) and has the substituents and structural features as described in the present application. Furthermore, the present application describes a pharmaceutical composition containing the compound as represented by Formula (I) or the pharmaceutically acceptable salt thereof, and the use of the compound as represented by Formula (I) or the pharmaceutically acceptable salt thereof and the pharmaceutical composition containing same in the preparation of a drug for preventing or treating RAD51 mediated diseases.

Abstract: A hidden fan and a fan lamp are disclosed. The hidden fan includes a turntable assembly and a plurality of fan blade assemblies arranged at the turntable assembly, the turntable assembly has a turntable and a limit wheel configured to rotate relative to the turntable, the turntable has a plurality of fan blade fixing portions, and the plurality of fan blade fixing portions are annularly arranged around a center of the turntable, at least one of the fan blade assemblies has a fan blade and a return elastic component, the fan blade has a fixed portion and a linkage portion arranged at a side of the fixed portion, the fixed portion is arranged at the corresponding fan blade fixing portion, the linkage portion is connected with the limit wheel.

Abstract: Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions that are estrogen receptor alpha dependent and/or estrogen receptor alpha mediated, including conditions characterized by excessive cellular proliferation, such as cancer.

Abstract: Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions that are estrogen receptor alpha dependent and/or estrogen receptor alpha mediated, including conditions characterized by excessive cellular proliferation, such as cancer.

Abstract: The present disclosure discloses a lens and a light source module. The lens includes a suction portion and at least two light distribution portions; each of the light distribution portions is configured to distribute light for a light emitting unit independently, and a plurality of light distribution portions are arranged around the suction portion with the suction portion as a center and are fixedly connected with the suction portion; each of the light distribution portions is provided with a light source cavity, a bonding surface and a light exiting surface, and the bonding surface and the light exiting surface face are away from each other, the light source cavity is a recess recessed in a direction from the bonding surface to the light exiting surface, the suction portion is provided with a suction surface, and the light exiting surface and the suction surface face are toward a same direction.

Abstract: The present invention relates to an indole macrocyclic derivative, a preparation method therefor and an application thereof in medicine. Specifically, the present invention relates to an indole macrocyclic derivative represented by general formula (IM), a preparation method therefor, a pharmaceutical composition containing the derivative, and a use thereof as a therapeutic agent, especially as an MCL-1 inhibitor. Each substituent of general formula (IM) is the same as those defined in the description.

Abstract: A ceiling lamp and a chassis are provided. The ceiling lamp includes a chassis and a light source module; the chassis includes a surrounding wall and a partition disposed within the surrounding wall, the partition divides a region surrounded by the surrounding wall into an assembly recess with a downward opening and a wiring recess with an upward opening; part of the partition protrudes upwardly into the wiring recess and forms a light source recess with a downward opening and an upward recess bottom, and the light source module is provided in the light source recess. The chassis includes a surrounding wall and a partition disposed within the surrounding wall, the partition divides a region surrounded by the surrounding wall into an assembly recess with a downward opening and a wiring recess with an upwardly opening.

Abstract: Disclosed are a pyrazolo-heteroaryl derivative, a preparation method and medical use thereof. In particular, this invention relates to a new pyrazolo-heteroaryl derivative as shown in the general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative and the use thereof as a therapeutic agent, in particular as a TLR7 agonist, wherein each substituent in the general formula (I) is defined in the description.

Abstract: Disclosed are a pyrazolo-heteroaryl derivative, a preparation method and medical use thereof. In particular, this invention relates to a new pyrazolo-heteroaryl derivative as shown in the general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative and the use thereof as a therapeutic agent, in particular as a TLR7 agonist, wherein each substituent in the general formula (I) is defined in the description.

Abstract: A heteroaryl-pyrazole derivative, and a preparation method therefor and a medical application thereof are described. Specifically, a new heteroaryl-pyrazole derivative as shown in formula (I), a preparation method for the derivative, a pharmaceutical composition containing the derivative, and a use of the derivative as a therapeutic agent, in particular as a TLR7 agonist, are described. The substituents in formula (I) have the same definitions as in the description.

Abstract: Disclosed are a pyridopyrimidine derivative as shown in general formula (I), a preparation method therefor and a pharmaceutical composition containing the derivative, and the use thereof as a therapeutic agent, particularly as a TLR8 agonist, wherein each substituent of general formula (I) is the same as those defined in the description.

Abstract: A hidden fan and a fan lamp are disclosed. The hidden fan includes a turntable assembly and a plurality of fan blade assemblies arranged at the turntable assembly, the turntable assembly has a turntable and a limit wheel configured to rotate relative to the turntable, the turntable has a plurality of fan blade fixing portions, and the plurality of fan blade fixing portions are annularly arranged around a center of the turntable, at least one of the fan blade assemblies has a fan blade and a return elastic component, the fan blade has a fixed portion and a linkage portion arranged at a side of the fixed portion, the fixed portion is arranged at the corresponding fan blade fixing portion, the linkage portion is connected with the limit wheel.

Abstract: Disclosed are a pyrazolo-heteroaryl derivative, a preparation method and medical use thereof. In particular, this invention relates to a new pyrazolo-heteroaryl derivative as shown in the general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative and the use thereof as a therapeutic agent, in particular as a TLR7 agonist, wherein each substituent in the general formula (I) is defined in the description.

Abstract: The invention disclosed herein relates to 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridinyl compounds and 4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridinyl compounds of Formula (A), pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of autoimmune diseases.

Abstract: The invention disclosed herein relates to 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridinyl compounds and 4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridinyl compounds of Formula (A), pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of autoimmune diseases.