Abstract: The present invention relates to a method of determining the number of copies of one or more RNA molecules in a population of RNA molecules and a method of determining the sequence of one or more RNA molecules in a population of RNA molecules, wherein the methods include a step of converting the population of RNA molecules to a population of DNA molecules comprising one or more base conversion, by error-prone reverse transcription. The present invention also relates to a population of DNA molecules obtained or obtainable by the methods disclosed herein.

Abstract: A heat exchanger plate module comprises a pressed heat exchanger plate and a flat plate, and a heat exchanger comprises plural of the modules. The plates comprise first and second longitudinal end portions each having a fluid port, and an intermediate heat exchange portion between the first and second longitudinal end portions. The plates further include a pressed corrugated pattern with alternating tops and bottoms in the thickness direction. The pressed pattern comprises in the first and/or second longitudinal end portions, a first fluid channel pattern leading fluid flow into the fluid port and/or a second fluid channel pattern bypassing the fluid port. In the intermediate heat exchange portion, a third fluid channel pattern fluidly communicates with the first and/or second fluid channel pattern and comprises longitudinally extending wave-shaped pressed lines that form discrete longitudinal extending fluid channels, when the pressed heat exchanger plate is attached to the flat plate.

Abstract: The present invention relates to the field of allergens and more specifically to a novel isolated allergen from the species Cupressaceae shown to be a primary sensitizer for severe peach allergy mediated by the protein Pru p7. The allergen is homologous with Pru P7 in peach, a protein belonging to the Gibberelin Regulating Proteins (GRPs). The novel allergen also 5 shares high sequence homology among other species from the Cupressaceae family and there is therefore also provided additional novel allergens in two other species of the Cupressaceae family. The novel allergens find use in the in vitro diagnosis of, treatment and/or prevention of Type 1 Cupressaceace pollen allergy and Cupressaceace pollen-associated food allergies.

Abstract: The present invention concerns a valve (1) for dispensing liquid substances from a closed and airtight container (3), the valve (1) comprising a valve housing (10) with a first end (10A) configured to be detachably attached to and in fluid communication with the container and a second end (10B) at which the liquid substance is to be dispensed in a dispensing direction by means of gravity. The dispensing valve (1) is useful in dispensing and has a more reliable and/or reproducible and simpler emptying of a closed and airtight/airproof container by means of an improved changing of air with liquid substance in the container when it is being emptied/dispensed.

Abstract: The invention relates to a novel horse allergen consisting of a heterodimeric protein having a first peptide chain and a second peptide chain together having an overall sequence identity of at least 70% with the combined sequences of SEQ ID NO:3 and SEQ ID NO: 4, as well as a single chain protein having an overall sequence identity of at least 70%, such as 75%, 80%, 85%, 90%, 95%, or 98%, with the combined amino acid sequences according to SEQ ID NO: 3 and SEQ ID NO: 4. The invention further relates to the use of the protein in methods of diagnosis and therapy of Type I allergy, and kits and compositions for use in such methods.

Abstract: The flash removal unit presented herein is suitable for a friction stir welding (FSW) head and includes a blade and an annular body. The blade removes flash created by a FSW tool during FSW operations. The an annular body defines a flash capture area around the blade and is configured to at least temporarily retain the flash removed by the blade within the flash capture area. The flash removal unit may also define a flow path along which the flash can be suctioned away from the flash removal unit.

Abstract: A plate heat exchanger comprising a casing, a fluid separation device, a number of heat transfer plates that are permanently joined to each other and have central openings that form a central space in the plate stack and in which the fluid separation device is arranged, such that a first part of the central opening may act as a fluid inlet and a second part of the central opening may act as a fluid outlet for a first fluid, opposite sides of the plates act fluid entries and exits for a second fluid, wherein two end plates have central through holes the ends of the plate stack, each of the end plates being thicker than the heat transfer plates, providing increased mechanical support for the plate stack, and having a slower thermal expansion.

Abstract: A plate heat exchanger comprises a plate package of permanently connected heat exchanger plates that defines a surrounding wall. Two mounting plates are permanently connected to an end surface of the plate package, in spaced relation to each other. Each mounting plate comprises opposing flat engagement surfaces and a peripheral edge that forms a perimeter of the mounting plate. Each mounting plate is arranged with one of its engagement surfaces permanently connected to the end surface, such that the peripheral edge partially extends beyond the outer periphery of the end surface, to define a mounting flange, and partially extends across the end surface in contact with the same. The mounting plates have a decreasing thickness towards the peripheral edge in predefined intersection regions, which are located where the peripheral edge intersects with the perimeter of the surrounding wall as seen in a normal direction to the end surface.

Abstract: The invention relates to a novel horse allergen consisting of a heterodimeric protein having a first peptide chain and a second peptide chain together having an overall sequence identity of at least 70% with the combined sequences of SEQ ID NO:3 and SEQ ID NO: 4, as well as a single chain protein having an overall sequence identity of at least 70%, such as 75%, 80%, 85%, 90%, 95%, or 98%, with the combined amino acid sequences according to SEQ ID NO: 3 and SEQ ID NO: 4. The invention further relates to the use of the protein in methods of diagnosis and therapy of Type I allergy, and kits and compositions for use in such methods.

Abstract: A frame configuration (I; II; III) for a vehicle (1) includes a forward part (10; 210) and a rear part (30; 130, 160; 230), the forward and rear parts are united by a first connection part (50; 150; 250) arranged between the forward and rear parts (10; 210, 30; 130, 160; 230) including a forward interface (G1) for connection with the forward part and a rear interface (G2) for connection with the rear part. Also a vehicle with the frame configuration is disclosed.

Abstract: A plate heat exchanger comprises a plate package of permanently connected heat exchanger plates that defines a surrounding wall. Two mounting plates are permanently connected to an end surface of the plate package, in spaced relation to each other. Each mounting plate comprises opposing flat engagement surfaces and a peripheral edge that forms a perimeter of the mounting plate. Each mounting plate is arranged with one of its engagement surfaces permanently connected to the end surface, such that the peripheral edge partially extends beyond the outer periphery of the end surface, to define a mounting flange, and partially extends across the end surface in contact with the same. The mounting plates have a decreasing thickness towards the peripheral edge in predefined intersection regions, which are located where the peripheral edge intersects with the perimeter of the surrounding wall as seen in a normal direction to the end surface.

Abstract: A frame configuration (I; II; III) for a vehicle (1) includes a forward part (10; 210) and a rear part (30; 130, 160; 230), the forward and rear parts are united by a first connection part (50; 150; 250) arranged between the forward and rear parts (10; 210, 30; 130, 160; 230) including a forward interface (G1) for connection with the forward part and a rear interface (G2) for connection with the rear part. Also a vehicle with the frame configuration is disclosed.

Abstract: A plate heat exchanger includes a plurality of heat exchanger plates formed of a metal sheet and permanently joined to each other by means of a braze material to form a plate package having first plate interspaces and second plate interspaces. Each heat exchanger plate has a pattern forming a heat transfer area and a plurality of porthole areas. Each heat exchanger plate extends along a main extension plane. The areas extend, on one side of the heat exchanger plate, between a primary level at a distance from the main extension plane and a secondary level at a distance from and on an opposite side of the main extension plane. Each heat exchanger plate has a depth defined by the distance between the primary level and the secondary level. The depth is equal to or less than 1.0 mm.

Abstract: A welding device applies weld material between two work pieces such that the work pieces are connected mechanically with one another. The welding device includes a welding head and a central element. The welding head performs a welding action during transport thereof along an operating direction between the work pieces. Two primary sensor members are arranged on the central element upstream of the welding head relative to the operating direction. The sensor members register geometric properties of a spacing between the work pieces in which spacing the weld material is to be applied. Each sensor member is configured to maintain contact with a respective wall of the two work pieces adjoining the spacing while allowing variation of lateral distances between the central element and the adjoining wall. This is accomplished by the sensor members being pivotally attached to the central element via at least one pivoting axis oriented essentially perpendicular to the operating direction.

Abstract: A plate heat exchanger including a plurality of heat exchanger plates joined to each other. Each plate has a heat transfer area, a first porthole area, a second porthole area, a third porthole area and a fourth porthole area. Each porthole area surrounds a porthole having a porthole edge. Each porthole area comprises an annular flat area, a set of inner portions on the annular flat area along the porthole edge, and a set of outer portions along the annular flat area at a distance from the inner portions. The outer portions of the first porthole area have a first relative peripheral position with respect to the inner portions. The outer portions of the fourth porthole area have a second relative peripheral position with respect to the inner portions. The first relative peripheral position includes a peripheral displacement in relation to the second relative peripheral position.

Abstract: A plate heat exchanger includes a plurality of heat exchanger plates. The plates are provided beside each other and permanently joined to each other to form a plate package having first plate interspaces and second plate interspaces. Each plate has a heat transfer area and four porthole areas defined by a porthole edge. Each of the porthole areas includes an annular flat area located at one of a primary and secondary level, and a set of inner portions on the annular flat area at the other of the primary and secondary level. Each inner portion has an inner part adjoining the porthole edge and an outer segment adjoining the inner part and having an angular extension of at least 180°. The outer segment has a continuous contour and a radius R, which is allowed to vary within the range 0.8R?R?1.2R.

Abstract: A plate heat exchanger including a plurality of heat exchanger plates (1), a first end plate and a second end plate. The plates are permanently joined to each other by means of a braze material. Each heat exchanger plate has a heat transfer area and a plurality of porthole areas surrounding a respective porthole. The plate heat exchanger including a plurality of having a bottom surface turned towards the heat exchanger plates. At least one of the flat elements including an annular protrusion extending from the bottom surface and tightly abutting one of the porthole areas of the outermost heat exchanger plate.

Abstract: A welding crane (1) for welding large structures is described. The welding crane (1) comprises a base part (2) which is arranged to be positioned on a ground (3), a mast (4) with a longitudinal axis (5). The mast (4) can be arranged in at least a first position in which the longitudinal axis (5) of the mast (4) extends substantially vertically from the base part (2). A boom (6) with a longitudinal axis (7) is arranged on the mast. The boom (6) can be arranged in at least a first position in which the longitudinal axis (7) of the boom (6) is substantially perpendicular to the longitudinal axis (5) of the mast (4). The boom (6) is arranged for receiving a welding head (13). The boom (6) is rotatable in relation to the mast (4) such that the boom (6) can be arranged in a second position in which the longitudinal axis (7) of the boom (6) is substantially parallel with the longitudinal axis (5) of the mast (4).

Abstract: A method may include sending personal network connection information from a mobile device to a guest device; sending authentication credentials from the mobile device to the guest device; receiving the authentication credentials in the personal network from the guest device; authenticating the guest device based on the authentication credentials; and granting access to the guest device to content stored in the personal network for a guest session.

Abstract: A welding crane (1) for welding large structures is described. The welding crane (1) comprises a base part (2) which is arranged to be positioned on a ground (3), a mast (4) with a longitudinal axis (5). The mast (4) can be arranged in at least a first position in which the longitudinal axis (5) of the mast (4) extends substantially vertically from the base part (2). A boom (6) with a longitudinal axis (7) is arranged on the mast. The boom (6) can be arranged in at least a first position in which the longitudinal axis (7) of the boom (6) is substantially perpendicular to the longitudinal axis (5) of the mast (4). The boom (6) is arranged for receiving a welding head (13). The boom (6) is rotatable in relation to the mast (4) such that the boom (6) can be arranged in a second position in which the longitudinal axis (7) of the boom (6) is substantially parallel with the longitudinal axis (5) of the mast (4).