Abstract: The present application provides a borate ester compound suitable for being used as a proteasome inhibitor, a preparation method and use thereof, and the compound has the following structure wherein, R1, R2 is asymmetric substituent in para-position, and R1 and R2 are both selected from the group consisting of halogen; and when R1 is F, R2 is not Cl; when R1 is Cl, R2 is not Br or F; and when R1 is Br, R2 is not Cl; X1, X2 is selected from the group consisting of hydroxyl, or X1 and X2 together form a substituted or unsubstituted 4 to 10 membered ring containing 1 to 4 heteroatoms being selected from the group consisting of O, N and S.

Abstract: This application provides a data storage method which is applied to a data storage device and includes: acquiring a first user identification and first user data of a first user; determining, from at least two preset distributed hosts in different areas, a first identification distributed host corresponding to the first user identification and a first data distributed host corresponding to the first user data; sending the first user identification to the first identification distributed host, so that the first identification distributed host stores the first user identification, and generates and stores a first identity identification corresponding to the first user identification; receiving the first identity identification; and sending the first identity identification and the first user data to the first data distributed host, so that the first data distributed host stores them in an associated manner.

Abstract: A vaporizer includes a base assembly and a vaporization core. The base assembly is provided with an air inlet channel in communication with the outside. The vaporization core forms a vaporization cavity and is configured to communicate with the air inlet channel of the base assembly. The vaporization core has a vaporization surface configured to vaporize a vaporization medium and define a part of a boundary of the vaporization cavity. A tangent of the air inlet channel at a connection point in communication with the vaporization cavity and a tangent of the vaporization surface form an acute angle.

Abstract: The present invention provides aryl phosphorous oxide compounds with kinase inhibitory activity. The compounds are capable of effectively inhibiting activity of various types of EGFR drug-resistant mutants (such as EGFRdel19, EGFRdel19/T790M, EGFRdel19/C797S, EGFRT790M/L858R, EGFRL858/C797S, EGFRdel19/T790M/C797S, and EGFRL858R/T790M/C797S, and also have significant inhibitory effect on ALK fusion genes and mutants (such as L1196M), and are capable of being used for the treatment, combined treatment or prevention of various types of cancers.

Abstract: This application provides a data storage method which is applied to a data storage device and includes: acquiring a first user identification and first user data of a first user; determining, from at least two preset distributed hosts in different areas, a first identification distributed host corresponding to the first user identification and a first data distributed host corresponding to the first user data; sending the first user identification to the first identification distributed host, so that the first identification distributed host stores the first user identification, and generates and stores a first identity identification corresponding to the first user identification; receiving the first identity identification; and sending the first identity identification and the first user data to the first data distributed host, so that the first data distributed host stores them in an associated manner.

Abstract: Disclosed is a method of high-precision 3D reconstruction of existing railway track lines based on UAV multi-view images, including: acquiring initial data, acquiring a UAV image rail top centerline, calculating a rail top centerline based on a nonlinear least squares method, and calculating three-dimensional coordinates of the rail centerline. Based on the multi-view geometry principle in computer vision and photogrammetry, object space coordinates of the line can be directly calculated by using image information, which does not require outdoor workers to work online and can effectively improve the safety of railway operation line surveying and mapping. Therefore, this method has important engineering application value and application prospect.

Abstract: The present invention discloses a low cost lean production bainitic steel wheel for rail transit and a manufacturing method therefor. The steel wheel contains elements with the following weight percentages: carbon C: 0.15-0.45%, silicon Si: 1.00-2.50%, manganese Mn: 1.20-3.00%, rare earth RE: 0.001-0.040%, phosphorus P?0.020%, and sulphur S?0.020%, where the remaining is iron and unavoidable residual elements, and 3.00%?Si+Mn?5.00%. Compared with the prior art, through alloying design and a preparation process, especially a heat treatment process and technology, a rim of the wheel obtains a carbide-free bainite structure, and a web and a wheel hub obtain granular bainite, a supersaturated ferritic structure, and a small amount of pearlite. The wheel has high comprehensive mechanical properties and service performance.

Abstract: A borate compound serving as a proteasome inhibitor, a preparation method for the borate compound and uses thereof.

Abstract: The present invention provides a high strength, high toughness, heat-cracking resistant bainite steel wheel for rail transportation and a manufacturing method thereof. Components are: carbon 0.10-0.40%, silicon 1.00-2.00%, manganese 1.00-2.50%, copper 0.20-1.00%, boron 0.0001-0.035%, nickel 0.10-1.00%, phosphorus ?0.020%, and sulphur ?0.020%, where the remaining is iron and unavoidable residual elements, 1.50%?Si+Ni?3.00%, and 1.50%?Mn+Ni+Cu?3.00%. Compared with the prior art, in the present invention, by using design of the chemical compositions of steel and wheel manufacturing processes, especially a heat treatment process and technology, a rim of the wheel obtains a carbide-free bainite structure, and a web and a wheel hub obtain a metallographic structure based on granular bainite and a supersaturated ferritic structure.

Abstract: The present application provides a borate ester compound suitable for being used as a proteasome inhibitor, a preparation method and use thereof, and the compound has the following structure wherein, R1, R2 is asymmetric substituent in para-position, and R1 and R2 are both selected from the group consisting of halogen; and when R1 is F, R2 is not Cl; when R1 is Cl, R2 is not Br or F; and when R1 is Br, R2 is not Cl; X1, X2 is selected from the group consisting of hydroxyl, or X1 and X2 together form a substituted or unsubstituted 4 to 10 membered ring containing 1 to 4 heteroatoms being selected from the group consisting of O, N and S.

Abstract: A semiconductor apparatus and its manufacturing method are presented. The method entails providing a substrate structure comprising a substrate, one or more fins positioned along a first direction on the substrate, and a separation region surrounding the fins. The separation region comprises a first separation region neighboring a first side of the fins and a second separation region neighboring a second side of the fins; forming a first and a second insulation layers on the substrate structure; forming a barrier layer; performing a first etching process using the barrier layer as a mask; removing the barrier layer; performing a second etching process using the remaining second insulation layer as a mask; forming a third insulation layer on side surfaces of the remaining first and second insulation layers; and performing a third etching process using the remaining second insulation layer and the third insulation layer as a mask.

Abstract: The present disclosure relates to the field of semiconductor technologies, and discloses semiconductor apparatus and manufacturing methods for the same.

Abstract: An image processing method and an image processing system are provided. A plurality of image detections are performed on the regions, such that the detections on the image data can adequately meet the variety of needs.

Abstract: The present disclosure provides an antenna and an electronic device. The antenna includes: a radiator, a feed terminal, a capacitive circuit, a resonant circuit, and a ground terminal. The feed terminal is electrically connected to a preset connection point on the radiator via the capacitive circuit. A first end of the resonant circuit is electrically connected to the radiator, and a second end of the resonant circuit is electrically connected to the ground terminal.

Abstract: A borate compound serving as a proteasome inhibitor, a preparation method for the borate compound and uses thereof.

Abstract: The present disclosure relates to the field of semiconductor technologies, and discloses semiconductor apparatus and manufacturing methods for the same.

Abstract: The present invention provides a high strength, high toughness, heat-cracking resistant bainite steel wheel for rail transportation and a manufacturing method thereof. Components are: carbon 0.10-0.40%, silicon 1.00-2.00%, manganese 1.00-2.50%, copper 0.20-1.00%, boron 0.0001-0.035%, nickel 0.10-1.00%, phosphorus?0.020%, and sulphur?0.020%, where the remaining is iron and unavoidable residual elements, 1.50%?Si+Ni?3.00%, and 1.50%?Mn+Ni+Cu?3.00%. Compared with the prior art, in the present invention, by using design of the chemical compositions of steel and wheel manufacturing processes, especially a heat treatment process and technology, a rim of the wheel obtains a carbide-free bainite structure, and a web and a wheel hub obtain a metallographic structure based on granular bainite and a supersaturated ferritic structure.

Abstract: A semiconductor apparatus and its manufacturing method are presented. The method entails providing a substrate structure comprising a substrate, one or more fins positioned along a first direction on the substrate, and a separation region surrounding the fins. The separation region comprises a first separation region neighboring a first side of the fins and a second separation region neighboring a second side of the fins; forming a first and a second insulation layers on the substrate structure; forming a barrier layer; performing a first etching process using the barrier layer as a mask; removing the barrier layer; performing a second etching process using the remaining second insulation layer as a mask; forming a third insulation layer on side surfaces of the remaining first and second insulation layers; and performing a third etching process using the remaining second insulation layer and the third insulation layer as a mask.

Abstract: The present disclosure relates to the technical field of semiconductor processes, and discloses a semiconductor device and a manufacturing method therefor.