Abstract: Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(?)-EGCG]. Use of PRO-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.

Abstract: Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(?)-EGCG]. Use of PRO-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.

Abstract: An ultrasound diagnosis apparatus which is connectable to a wireless probe that acquires first data by scanning an object is provided. The ultrasound diagnosis apparatus includes a controller which is configured to recognize an occurrence of a first event, to automatically terminate a first communication connection to the wireless probe via a first communication network, and to control an automatic start of a second communication connection to an external apparatus via the first communication network; and a communicator which is configured to exchange data with the wireless probe and/or with the external apparatus by using the first communication network under the control of the controller.

Abstract: A synthetic world interface may be used to model digital environments, sensors, and motions for the evaluation, development, and improvement of computer vision and speech algorithms. A synthetic data cloud service with a library of sensor primitives, motion generators, and environments with procedural and game-like capabilities, facilitates engineering design for a manufactural solution that has computer vision and speech capabilities. In some embodiments, a sensor platform simulator operates with a motion orchestrator, an environment orchestrator, an experiment generator, and an experiment runner to test various candidate hardware configurations and computer vision and speech algorithms in a virtual environment, advantageously speeding development and reducing cost. Thus, examples disclosed herein may relate to virtual reality (VR) or mixed reality (MR) implementations.

Abstract: A synthetic world interface may be used to model digital environments, sensors, and motions for the evaluation, development, and improvement of localization algorithms. A synthetic data cloud service with a library of sensor primitives, motion generators, and environments with procedural and game-like capabilities, facilitates engineering design for a manufactural solution that has localization capabilities. In some embodiments, a sensor platform simulator operates with a motion orchestrator, an environment orchestrator, an experiment generator, and an experiment runner to test various candidate hardware configurations and localization algorithms in a virtual environment, advantageously speeding development and reducing cost. Thus, examples disclosed herein may relate to virtual reality (VR) or mixed reality (MR) implementations.

Abstract: Systems and methods are disclosed for using a synthetic world interface to model environments, sensors, and platforms, such as for computer vision sensor platform design. Digital models may be passed through a simulation service to generate synthetic experiment data. Systematic sweeps of parameters for various components of the sensor or platform design under test, under multiple environmental conditions, can facilitate time- and cost-efficient engineering efforts by revealing parameter sensitivities and environmental effects for multiple proposed configurations. Searches through the generated synthetic experimental data results can permit rapid identification of desirable design configuration candidates.

Abstract: Methods, systems, and computer programs for providing an option to a player to participate in a competition game of the online game includes monitoring a game play of an online game by a player to determine the player has reached a threshold level that qualifies the player to participate in a competition game. Upon determining the player is qualified, the player is assigned to a class and a division that includes other players that are participating in the competition game. A time period for the competition game is set and the player is enabled to participate in a plurality of game sprints during the time period. Each game sprint spans a sprint time and is associated with a game sprint score. A highest game sprint score of the player is determined from amongst the plurality game sprints. The highest game sprint score is used to rank the player in the division for the competition game.

Abstract: Methods, systems, and computer programs are presented for adjusting bonus winning odds while playing an online slots game. A server is configured to provide access to remote users having user accounts for playing the online slots game over a network connection and is configured to establish a plurality of tiers for playing the online slots game that includes turns. Each tier is assigned an odds value for winning a chance to play a bonus game that is different from the online slots game. The method enables play of each turn, wherein chances to win the bonus game at each turn are based a selected tier. The method includes presenting to the graphical user interface images associated with the bonus game when a player wins the chance to play the bonus game during a turn, and presenting to the graphical user interface options to send challenge bonus game to a friend. Play by the friend of the sent challenge game adds to winnings of said bonus game to the player.

Abstract: Facilitation of monitoring and analysis of user motion is performed to facilitate detecting when a user has fallen. A device can comprise a housing configured to attach to a body part of a human, a sensor module configured to capture motion data corresponding to motion of an object to which the device is attached, and a communication module configured to communicatively couple the sensor module to another device and transmit the motion data to the other device, wherein the motion data is configured to be analyzed by the other device to determine a type of the motion of the object, and in response to a determination that the type of motion is a falling motion, the other device is configured to activate a notification mechanism to notify an entity that the human has fallen.

Abstract: Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(?)-EGCG]. Use of PRO-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.

Abstract: The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II): processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.

Abstract: The present invention relates to ionic liquids for use in chemical applications and capable of serving the dual function of solvent and liquid support. The ionic liquid lends itself to a method of synthesizing oligomers selected from the group consisting of oligopeptides, oligosaccharides and oligonucleotides, comprising contacting a first monomer unit with an ionic liquid at reaction conditions to provide an ionic liquid bound monomer unit; and contacting the ionic liquid bound monomer unit with at least one further monomer unit at reaction conditions to provide an ionic liquid bound oligomer comprising from 2 to 30 monomer units. The method lends itself to large scale manufacture of oligopeptides, oligosaccharides and oligonucleotides.

Abstract: A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (Az 1-15) and alkynes (Ac 1-17). These triazole bridged flavonoid dimers and their precursor alkyne- and azide-containing flavonoids were screened for their ability to modulate multidrug resistance (MDR) in P-gp-overexpressed cell line (LCC6MDR), MRP1-overexpressed cell line (2008/MRP1) and BCRP-overexpressed cell line (HEK293/R2 and MCF7-MX100). Generally, they displayed very promising MDR reversal activity against P-gp-, MRP1- and BCRP-mediated drug resistance. Moreover, they showed different levels of selectivity for various transporters. Overall, they can be divided into mono-selective, dual-selective and multi-selective modulators for the P-gp, MRP1 and BCRP transporters.

Abstract: Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(?)-EGCG]. Use of Pro-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.

Abstract: Provided are a method and system for implementing alarms for a medical device through a mobile device. The method includes: storing details of examination of a specimen (hereinafter, referred to as examination details) in the medical device, wherein the storing is performed by the medical device; accessing the medical device and establishing a connection with the medical device, wherein the accessing and the establishing of the connection is performed by the mobile device; reading the examination details stored in the medical device, wherein the reading is performed by the mobile device; analyzing the read examination details, wherein the analyzing is performed by the mobile device; and implementing an alarm if the result of analysis satisfies a predetermined criterion, wherein the implementing is performed by the mobile device.

Abstract: The present invention relates to ionic liquids for use in chemical applications and capable of serving the dual function of solvent and liquid support. The ionic liquid lends itself to a method of synthesizing oligomers selected from the group consisting of oligopeptides, oligosaccharides and oligonucleotides, comprising contacting a first monomer unit with an ionic liquid at reaction conditions to provide an ionic liquid bound monomer unit; and contacting the ionic liquid bound monomer unit with at least one further monomer unit at reaction conditions to provide an ionic liquid bound oligomer comprising from 2 to 30 monomer units. The method lends itself to large scale manufacture of oligopeptides, oligosaccharides and oligonucleotides.

Abstract: A stator assembly comprises a first core member and a plurality of second core members. The first core member comprises a first core member body, a plurality of cores and a plurality of receiving recesses. Each of the cores comprises a first yoke portion, a first tooth portion, a first coil and a first insulating bobbin. The second core member comprises a second yoke portion, a second tooth portion, a second coil and a second insulating bobbin. The first core member is engageable with the plurality of second core members in a manner such that the second yoke portions are fixedly received in the receiving recesses respectively with each of the second core members arranged interposed between each adjacent pair of cores so that the arc-shaped ends of the first tooth portions and the second tooth portions form an annular shape.

Abstract: Filamenting temperature-sensitive mutant Z (FtsZ) protein plays a crucial role in the bacterial cell division machinery and is a validated drug target for antibacterial agents. The present invention relates to FtsZ-interacting compounds that possess a 2,4,6-trisubstituted pyrimidine scaffold. Some of these compounds possess potent anti-staphylococcal properties and potent antibacterial activities against clinically isolated MRSA strains. Compounds have been identified to exhibit low spontaneous frequency of resistance, low toxicity as well as the ability to rescue G. mellonella larvae infected with lethal dose of the MRSA ATCC 43300 strain. Characterization by saturation transfer difference NMR, light scattering assay and GTPase hydrolysis assay with purified S. aureus FtsZ protein verified the interaction of 2,4,6-trisubstituted pyrimidine with the FtsZ protein, further confirmed by observations of iconic filamentous cell phenotype and mislocalization of the Z-ring formation.

Abstract: Methods, systems, and computer programs are presented for adjusting bonus winning odds while playing an online slots game. A server is configured to provide access to remote users having user accounts for playing the online slots game over a network connection and is configured to establish a plurality of tiers for playing the online slots game that includes turns. Each tier is assigned an odds value for winning a chance to play a bonus game that is different from the online slots game. The method enables play of each turn, wherein chances to win the bonus game at each turn are based a selected tier. The method includes presenting to the graphical user interface images associated with the bonus game when a player wins the chance to play the bonus game during a turn, and presenting to the graphical user interface options to send challenge bonus game to a friend. Play by the friend of the sent challenge game adds to winnings of said bonus game to the player.

Abstract: The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II) processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.