Abstract: The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia.

Abstract: The present invention relates to chemical compounds that can in particular be used as structural mimetics of proline-rich peptides. The compounds of the present invention are capable of selectively inhibiting ena/VASP-EVH1-mediated protein-protein interactions. The invention further relates to the use of said compounds as pharmaceutical agents and to the use of the pharmaceutical agents to treat tumor diseases. The chemical compounds of the present invention can significantly inhibit the chemotaxis and motility of invasive tumor cells and can therefore be used in the treatment and/or prevention of tumor metastases.

Abstract: A method of manufacturing a transfer assembly for transferring articles from a first moving carrier to a second moving carrier is provided. The method comprises providing a programmable motor and a motor control system. The motor control system and the programmable motor define an excitation frequency. The method comprises providing a carrier member comprising a housing comprising a wall and shifting a natural frequency of the carrier member by forming the wall with a first carbon fiber layer having a first fiber orientation extending in a first direction and with a second carbon fiber layer having a second fiber orientation extending in a second direction that is different than the first direction. The shifting the natural frequency establishes the natural frequency of the carrier member to be at least 1.1 times greater than or at least 1.1 times less than the excitation frequency.

Abstract: An apparatus for transferring one or more articles from a first carrier moving at a first speed to a second carrier moving at a second speed that is different than the first speed is provided. The apparatus comprises a programmable motor and a carrier member operably engaged with the programmable motor. The carrier member comprises a housing comprising a wall and an outer surface configured to receive the one or more articles from the first moving carrier in a receiving zone and configured to deposit the one or more articles onto the second moving carrier in an application zone. The wall comprises carbon fiber. The programmable motor is configured to move the outer surface of the housing at a third speed through the receiving zone and at a fourth speed through the application zone.

Abstract: A method of manufacturing a transfer assembly for transferring articles from a first moving carrier to a second moving carrier is provided. The method comprises providing a programmable motor and a motor control system. The motor control system and the programmable motor define an excitation frequency. The method comprises providing a carrier member comprising a housing comprising a wall and shifting a natural frequency of the carrier member by forming the wall with a first carbon fiber layer having a first fiber orientation extending in a first direction and with a second carbon fiber layer having a second fiber orientation extending in a second direction that is different than the first direction. The shifting the natural frequency establishes the natural frequency of the carrier member to be at least 1.1 times greater than or at least 1.1 times less than the excitation frequency.

Abstract: An apparatus for transferring one or more articles from a first carrier moving at a first speed to a second carrier moving at a second speed that is different than the first speed is provided. The apparatus comprises a programmable motor and a carrier member operably engaged with the programmable motor. The carrier member comprises a housing comprising a wall and an outer surface configured to receive the one or more articles from the first moving carrier in a receiving zone and configured to deposit the one or more articles onto the second moving carrier in an application zone. The wall comprises carbon fiber. The programmable motor is configured to move the outer surface of the housing at a third speed through the receiving zone and at a fourth speed through the application zone.

Abstract: A device arranges an edge protector on a package. The device includes a drive wheel for moving the device along a guiding rail from a point of departure to the package and from the package to the point of departure. A motor is carried by the device and drives the drive wheel. A clamp mount includes a movable clamping jaw and a counter bearing for taking up the edge protector in an open position of the clamping jaw and to hold it in a closed position of the clamping jaw. The motor drives the drive wheel and acts on a power transmission assembly to induce opening and closing of the clamping jaw. A device for strapping packages having the edge protector applicator includes a frame carrying a press plate above a vertically movable packing table. The press plate has running rails on which the edge protector applicator is movably mounted. The applicator device is mounted below the press plate.

Abstract: The invention relates to compounds that can be used, in particular, as structural mimetics of proline-rich peptides and are correspondingly able to bond with proline-rich-motif binding domains (PRM domains) of proteins. The invention further relates to the use of these compounds as pharmaceutically active agents, as well as the use of the pharmaceutically active agents for the treatment of bacterial, neurodegenerative and tumor diseases.

Abstract: The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia.

Abstract: The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia.

Abstract: A lifting apparatus having a tool, which is vertically displaceable by means of a motor and to which at least a first toothed wheel is coupled in terms of movement. The toothed wheel engages over the vertical path of displacement in a stationary toothed rack. The lifting gear includes a safety device having a blocking element which, in a locked position, stops the tool from moving in the direction of gravity, at least when the lifting apparatus is deenergized, wherein the blocking element stops the tool over the vertical path of displacement, at basically any level in any vertical position, and is held against a restoring force in an unblocking position with vertical movement of the tool, and the restoring force pushes the blocking element into its locked position, at least when the lifting apparatus is deenergized.

Abstract: The invention relates to compounds that can be used, in particular, as structural mimetics of proline-rich peptides and are correspondingly able to bond with proline-rich-motif binding domains (PRM domains) of proteins. The invention further relates to the use of these compounds as pharmaceutically active agents, as well as the use of the pharmaceutically active agents for the treatment of bacterial, neurodegenerative and tumor diseases.

Abstract: In the heat utilization installation (1) according to the invention several heat sources (2) are included which are provided each with a jet pump (16), (17), (18), (19). The heat sources (2) are connected to a heat carrier circuit system (7) which includes a single, central circulating pump or circulating pump unit (20). The individual jet pumps (16) to (19) are so controlled for the respective heat sources (2), the required operating temperatures with respect to temperature difference between the outlet and inlet and the flow volume are maintained or achieved. With the possibility of independent control of the flow volumes at the various heat sources (2), uniform fluid temperatures as required for a buffer store (22) or heat consumers can be maintained.

Abstract: Substituted tricyclic diproline analogues of the formula (I): wherein the variables are as defined herein. Also disclosed are methods for the production thereof, the use thereof for the induction of an alpha-helix conformation in peptides and/or proteins, pharmaceuticals containing said compounds, methods for the production of a peptide library containing said compounds, and peptide libraries containing said compounds.

Abstract: A transport unit is provided for cylindrical cargo items supported on a support surface and arranged in parallel in at least two layers. The center axes of cargo items are arranged on top of one another and extend essentially in the same vertical plane. At least one tension device extends between two layers. The tension device extends from an outside edge of a cargo item to an outside edge of an opposing cargo item in the layer. At least two stop elements are positioned on respective ends of the tension device. The stop elements are formed for engaging the cargo items and at least one of the stop elements being adjustably positionable on one end of the tension device. The stop elements being connectable by the tension device in a force transferring manner relative to the cargo items.

Abstract: A transport unit including a plate shaped transport base with cylindrical cargo objects placed there on disposed with their center axes parallel to one another and in at least one layer, wherein the center axes respectively have a distance from one another and wherein enveloping surfaces of adjacent objects are in a line contact with one another, and cargo securing devices configured as tension devices, through which the objects are secured on the base against sliding or rolling. A base which is characterized by an improved utilization of the transport volume and for which the fixation of the objects can be provided in a simply and comfortably, it is provided that tension devices engage a face of the objects and at least each object disposed at an edge of a layer is connected at the face with a tension device in a force transmitting manner.

Abstract: The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia.

Abstract: A substantially copper-free friction material for a brake pad includes a binder forming approximately 8-18% by volume, a fiber forming 5-14% by volume, at least one lubricant forming up to 6% by volume, at least one abrasive forming 10-27% by volume, at least one carbon content component forming 36-51% by volume, and at least one filler forming 6-21% by volume. The friction material can be applied to the backing plate of a brake pad.

Abstract: A lifting apparatus having a tool, which is vertically displaceable by means of a motor and to which at least a first toothed wheel is coupled in terms of movement. The toothed wheel engages over the vertical path of displacement in a stationary toothed rack. The lifting gear includes a safety device having a blocking element which, in a locked position, stops the tool from moving in the direction of gravity, at least when the lifting apparatus is deenergized, wherein the blocking element stops the tool over the vertical path of displacement, at basically any level in any vertical position, and is held against a restoring force in an unblocking position with vertical movement of the tool, and the restoring force pushes the blocking element into its locked position, at least when the lifting apparatus is deenergized.

Abstract: A propeller for a marine propulsion system is disclosed which comprises a propeller hub having a casing formed from three segments (16a, 16b, 16c), each of which has a part of an opening (28) for mounting a propeller blade (34). A locking and unlocking mechanism (51, 54, 95, 100) is provided for disengaging the propeller blades to enable pitch adjustment of the blades. A push rod (50) is connected to the mechanism (100) to cause disengagement and adjustment of the pitch of the blades. The mechanism (100) includes a claw (101) having pivotally connected fingers (95). The hub also has a slide ring (51) having a load surface (61) is provided for receiving load when the propeller blades are unlocked to enable pitch adjustment to take place.